Orogard

Each chip contains Chlorhexidine gluconate (Orogard) gluconate 2.5 mg in a biodegradable matrix of hydrolyzed gelatin (cross-linked with glutaraldehyde).

Chlorhexidine gluconate (Orogard) also contains glycerin and purified water as excipients.

Chlorhexidine gluconate (Orogard) gluconate, an antimicrobial agent, is 1, 1'-hexamethylenebis [5-(p-chlorophenyl)biguanide] di-D-gluconate. Molecular Formula: C₂₂H₃₀Cl₂N₁₀·2C₆H₁₂O₇. Molecular Weight: 897.8.

Sodium Sodium fluoride (Orogard) is an inorganic chemical compound. A colorless solid, it is a source of the Sodium fluoride (Orogard) ion in diverse applications. Sodium Sodium fluoride (Orogard) is less expensive and less hygroscopic than the related salt potassium Sodium fluoride (Orogard).

Zinc chloride (Orogard) Capsule: Each capsule contains Zinc chloride (Orogard) sulphate monohydrate 54.93 mg, thiamine nitrate 10 mg, riboflavin 10 mg, pyridoxine hydrochloride 3 mg, vitamin B12 (coated) equivalent to cyanocobalamin 15 mcg, ascorbic acid 150 mg, folic acid 1 mg, nicotinamide 50 mg and calcium pantothenate 12.5 mg.

Zinc chloride (Orogard) Syrup: Each 5 mL contains Zinc chloride (Orogard) gluconate 34.9 mg, thiamine mononitrate 2.5 mg, riboflavin 2.5 mg, pyridoxine hydrochloride 1 mg, cyanocobalamin 3 mcg, ascorbic acid 50 mg, d-panthenol 12.5 mg and niacinamide 25 mg in a flavoured liquid glucose sorbitol syrup base.

Gluconato de clorhexidina (Orogard) ® (gluconato de clorhexidina (Orogard)

El enjuague oral USP, 0.12%) está indicado para su uso entre visitas dentales como parte de un programa profesional para el tratamiento de la gingivitis, caracterizada por enrojecimiento e hinchazón de las gingivas, incluido el sangrado gingival al sondear. El gluconato de clorhexidina (Orogard) ® no se ha probado entre pacientes con gingivitis ulcerosa necrotizante aguda (ANUG). Para pacientes que tienen gingivitis y periodontitis coexistentes, ver PRECAUCIONES

Oral

Profilaxis de caries dental

Adulto: Per loz contiene 1 mg de fluoruro de sodio (Orogard): 1 loz al día, independientemente del contenido de fluoruro de sodio (Orogard) del agua potable.

Niño: Basado en el contenido de fluoruro de sodio (Orogard) del agua potable: contenido de fluoruro de agua y sodio (Orogard) <0.3 ppm: 6 mth-3 años: 0.25 mg diarios; 3-6 años: 0.5 mg diarios; > 6 años: 1 mg al día. Contenido de fluoruro de agua y sodio (Orogard) 0.3-0.6 ppm: <3 años: No recomendado; 3-6 años: 0.25 mg diarios; > 6 años: 0.5 mg diarios. Las tabletas deben ser succionadas o masticadas antes de tragarlas.

Tópico / Cutáneo

Profilaxis de caries dental

Adulto: Como soluciones de enjuague al 0.2% o 0.05%: enjuague 10 ml una vez al día o al agua, preferiblemente al acostarse después de cepillarse los dientes. Enjuague la solución alrededor y entre los dientes durante 1 minuto y escupe después de enjuagar. Como gel que contiene 1.1% de fluoruro de sodio y sodio (Orogard): aplique una capa delgada del gel en los dientes diariamente (preferiblemente al acostarse después de cepillarse los dientes) con un cepillo de dientes o una bandeja para la boca durante al menos 1 minuto y escupe después de la aplicación. Para obtener el máximo beneficio, no coma, beba ni enjuague la boca durante al menos 30 minutos después de usar la solución de enjuague o el gel dental.

Niño: ≥6 años: como soluciones de enjuague al 0.2% o 0.05%: enjuague 10 ml una vez al día o al agua, preferiblemente al acostarse después de cepillarse los dientes. Enjuague la solución alrededor y entre los dientes durante 1 minuto y escupe después de enjuagar. Como gel que contiene 1.1% de fluoruro de sodio y sodio (Orogard): aplique una capa delgada del gel en los dientes diariamente (preferiblemente al acostarse después de cepillarse los dientes) con un cepillo de dientes o una bandeja para la boca durante al menos 1 minuto y escupe después de la aplicación. Enjuague bien la boca después de escupir el gel.

El ácido salicílico se usa para tratar muchos trastornos de la piel, como el acné, la caspa, la psoriasis, la dermatitis seborreica de la piel y el cuero cabelludo, callos, callos, verrugas comunes y verrugas plantares, dependiendo de la forma de dosificación y la fuerza de la preparación.

Gluconato de clorhexidina (Orogard) El gluconato es un enjuague bucal germicida que reduce las bacterias en la boca.

El enjuague oral con gluconato de clorhexidina (Orogard) se usa para tratar la gingivitis (hinchazón, enrojecimiento, sangrado de las encías). El gluconato de clorhexidina (Orogard) generalmente es recetado por un dentista.

El enjuague oral con gluconato de clorhexidina (Orogard) no es para tratar todo tipo de gingivitis. Use el medicamento solo para tratar la afección para la que se lo recetó su dentista. No comparta este medicamento con otra persona, incluso si tiene los mismos síntomas de encía que usted tiene.

El gluconato de clorhexidina (Orogard) también se puede usar para fines no enumerados en esta guía de medicamentos.

Fluoruro de sodio (Orogard) es una sustancia que fortalece el esmalte dental. Esto ayuda a prevenir las caries dentales.

El fluoruro de sodio (Orogard) se usa como medicamento para prevenir la caries dental en personas que tienen un bajo nivel de fluoruro de sodio (Orogard) en su agua potable. El fluoruro de sodio (Orogard) también se usa para prevenir la caries dental en personas que sufren radiación de la cabeza y / o el cuello, lo que puede causar sequedad de la boca y una mayor incidencia de caries dental.

El fluoruro de sodio (Orogard) también se puede usar para otros fines que no figuran en esta guía de medicamentos.

Cloruro de zinc (Orogard) Es un mineral natural. El cloruro de zinc (Orogard) es importante para el crecimiento y para el desarrollo y la salud de los tejidos corporales.

El sulfato de cloruro de zinc (Orogard) se usa para tratar y prevenir la deficiencia de cloruro de zinc (Orogard).

El sulfato de cloruro de zinc (Orogard) también se puede usar para fines no enumerados en esta guía de medicamentos.

One Chlorhexidine gluconate (Orogard) is inserted into a periodontal pocket with probing pocket depth (PD) 5 mm or greater. Up to 8 chips may be inserted in a single visit. Treatment is recommended to be administered once every three months in pockets with PD remaining 5 mm or greater. The periodontal pocket should be isolated and the surrounding area dried prior to chip insertion.

The Chlorhexidine gluconate (Orogard) should be grasped using forceps (such that the rounded end points away from the forceps) and inserted into the periodontal pocket to its maximum depth. If necessary, the Chlorhexidine gluconate (Orogard) can be further maneuvered into position using the tips of the forceps or a flat instrument. The Chlorhexidine gluconate (Orogard) does not need to be removed since it biodegrades completely.

In the unlikely event of Chlorhexidine gluconate (Orogard) dislodgement (in the two pivotal clinical trials, only 8 chips were reported lost), several actions are recommended, depending on the day of Chlorhexidine gluconate (Orogard) loss. If dislodgement occurs 7 days or more after placement, the dentist should consider the subject to have received a full course of treatment. If dislodgement occurs within 48 hours after placement, a new Chlorhexidine gluconate (Orogard) should be inserted. If dislodgement occurs more than 48 hours after placement, the dentist should not replace the Chlorhexidine gluconate (Orogard), but reevaluate the patient at 3 months and insert a new Chlorhexidine gluconate (Orogard) if the pocket depth has not been reduced to less than 5 mm.

How supplied

Chlorhexidine gluconate (Orogard) (Chlorhexidine gluconate (Orogard) gluconate) 2.5 mg is supplied as a small, orange-brown, rectangular chip (rounded at one end), in cartons of 20 chips (NDC 52096-001-22). Each chip is individually packed in a separate compartment of an aluminum blister pack.

Store at 20° - 25°C with excursions permitted to 15° - 30° C (59° - 86°F).

Manufactured by: Dexcel® Pharma Technologies Ltd, HaMarpeh 7 St.,Jerusalem 91237, Israel. Distributed by: Adrian Pharmaceuticals, Spring Hill, Florida 34606. Iss. 01/10

Oral

Prophylaxis of dental caries

Adult: Per loz contains 1 mg Sodium fluoride (Orogard): 1 loz daily regardless of Sodium fluoride (Orogard) content of drinking water.

Child: Based on Sodium fluoride (Orogard) content of drinking water: Water-Sodium fluoride (Orogard) content <0.3 ppm: 6 mth-3 yr: 0.25 mg daily; 3-6 yr: 0.5 mg daily; >6 yr: 1 mg daily. Water-Sodium fluoride (Orogard) content 0.3-0.6 ppm: <3 yr: Not recommended; 3-6 yr: 0.25 mg daily; >6 yr: 0.5 mg daily. Tablets should be sucked or chewed before swallowing.

Topical/Cutaneous

Prophylaxis of dental caries

Adult: As 0.2% or 0.05% rinsing solutions: Rinse 10 mL once daily or wkly, preferably at bedtime after brushing the teeth. Rinse solution around and between teeth for 1 minute and spit after rinsing. As gel containing 1.1% sodium Sodium fluoride (Orogard): Apply a thin layer of the gel to the teeth daily (preferably at bedtime after brushing the teeth) using a toothbrush or mouth tray for at least 1 minute and spit after application. For max benefit, do not eat, drink or rinse their mouth for at least 30 minutes after using the rinsing solution or dental gel.

Child: ≥6 yr: As 0.2% or 0.05% rinsing solutions: Rinse 10 mL once daily or wkly, preferably at bedtime after brushing the teeth. Rinse solution around and between teeth for 1 minute and spit after rinsing. As gel containing 1.1% sodium Sodium fluoride (Orogard): Apply a thin layer of the gel to the teeth daily (preferably at bedtime after brushing the teeth) using a toothbrush or mouth tray for at least 1 minute and spit after application. Rinse the mouth thoroughly after spitting the gel.

Dosage Forms

Excipient information presented when available (limited, particularly for generics); consult specific product labeling.

Solution,

Intravenous [preservative free]:

Generic: 1 mg/mL (10 mL)

Dosing: Adult

Parenteral nutrition, maintenance requirement:

Acute metabolic states: 4.5 to 6 mg/day

Metabolically stable: 2.5 to 5 mg/day (ASPEN [Vanek 2012])

Stable with fluid loss from small bowel: 12.2 mg Zinc chloride (Orogard)/L TPN or 17.1 mg Zinc chloride (Orogard)/kg (added to 1000 mL IV fluids) of stool or ileostomy output

Note: Clinical response from deficiency may not occur for up to 6 to 8 weeks.

Dosing: Geriatric

Refer to adult dosing.

Dosing: Pediatric

Note: Dosages may be presented in units of mcg or mg, use caution to ensure correct units. Clinical response may not occur for up to 6 to 8 weeks:

Parenteral nutrition, maintenance Zinc chloride (Orogard) requirement:

Age-directed dosing (ASPEN [Vanek 2012]):

Infants <3 months: IV: 250 mcg/kg/day elemental Zinc chloride (Orogard) as an additive to parenteral nutrition solution.

Infants ≥3 months: IV: 50 mcg/kg/day elemental Zinc chloride (Orogard) as an additive to parenteral nutrition solution.

Children: 50 mcg/kg/day elemental Zinc chloride (Orogard) as an additive to parenteral nutrition solution; maximum daily dose: 5,000 mcg/day.

Weight-directed dosing (ASPEN [Mirtallo 2004]):

Infants <10 kg: 50 to 250 mcg/kg/day elemental Zinc chloride (Orogard) as an additive to parenteral nutrition solution.

Children 10 to 40 kg: 50 to 125 mcg/kg/day elemental Zinc chloride (Orogard) as an additive to parenteral nutrition solution; maximum daily dose: 5,000 mcg/day.

Children and Adolescents >40 kg: 2,000 to 5,000 mcg/day elemental Zinc chloride (Orogard) as an additive to parenteral nutrition solution.

See also:
What is the most important information I should know about Chlorhexidine gluconate (Orogard)?

You should not use this medication if you are allergic to Chlorhexidine gluconate (Orogard) gluconate.

If you have periodontal disease, you may need special treatments while you are using Chlorhexidine gluconate (Orogard) gluconate.

Chlorhexidine gluconate (Orogard) gluconate oral rinse is not for treating all types of gingivitis. Use the medication only to treat the condition your dentist prescribed it for. Do not share this medication with another person, even if they have the same gum symptoms you have.

Do not give this medication to a child or teenager without a doctor's advice.

Do not add water to Chlorhexidine gluconate (Orogard) gluconate oral rinse. Do not rinse your mouth with water or other mouthwashes right after using Chlorhexidine gluconate (Orogard) gluconate.

Avoid eating, drinking, or brushing your teeth just after using this medication.

Do not use any other mouthwash unless your doctor has told you to.

Chlorhexidine gluconate (Orogard) gluconate can stain teeth, dentures, tooth restorations, your tongue, or the inside of your mouth. Talk with your dentist about ways to remove staining from these surfaces. Stains may be harder to remove from false teeth that have scratches in their surfaces.

Visit your dentist at least every 6 months for preventive tooth and gum care.

See also:
What is the most important information I should know about Sodium fluoride (Orogard)?

ReNaf Sodium fluoride (Orogard) Chewable Tablets 1.0 mg are contraindicated when the Sodium fluoride (Orogard) content of drinking water is 0.3 ppm F- or more and should not be administered to children under age 6 years. ReNaf Sodium fluoride (Orogard) Chewable Tablets 0.5 mg are contraindicated when the Sodium fluoride (Orogard) content of drinking water is more than 0.6 ppm F- and should not be administered to children underage 6 when the Sodium fluoride (Orogard) content of drinking water is 0.3 ppm F- or more or to children under age 3 years. ReNaf Sodium fluoride (Orogard) Chewable Tablets 0.25 mg are contraindicated when the Sodium fluoride (Orogard) content of drinking water is more than 0.6 ppm F- and should not be administered to children under age 3 years when the Sodium fluoride (Orogard) content of drinking water is 0.3 ppm F- or more. Do not administer any strength of ReNaf Sodium fluoride (Orogard) Chewable Tablets to children under age 6 months. ReNaf Sodium fluoride (Orogard) Chewable Tablets are not indicated for use in adults.

See also:
What is the most important information I should know about Zinc chloride (Orogard)?

Less common or rare

Skin irritation not present before use of salicylic acid (moderate or severe)

Frequency not known

Dryness and peeling of skin

flushing

redness of skin

unusually warm skin

Symptoms of salicylic acid poisoning

Confusion

diarrhea

dizziness

fast or deep breathing

headache (severe or continuing)

hearing loss

lightheadedness

nausea

rapid breathing

ringing or buzzing in ears (continuing)

severe drowsiness

stomach pain

vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

-Skin irritation not present before use of salicylic acid (mild) -stinging

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Rinse your mouth with Chlorhexidine gluconate (Orogard) gluconate twice daily after brushing your teeth.

Measure your dose using the cup provided with the medication. Swish the medicine in your mouth for at least 30 seconds, then spit it out. Do not swallow the mouthwash.

Do not add water to the oral rinse. Do not rinse your mouth with water or other mouthwashes right after using Chlorhexidine gluconate (Orogard) gluconate.

Chlorhexidine gluconate (Orogard) gluconate may leave an unpleasant taste in your mouth. Do not rinse your mouth to remove this taste after using the medication. You may rinse the medicine away and reduce its effectiveness.

Use this medication for the full prescribed length of time. Your symptoms may improve before your gingivitis is completely cleared. Chlorhexidine gluconate (Orogard) gluconate will not treat a viral or fungal infection such as cold sores, canker sores, or oral thrush (yeast infection).

Visit your dentist at least every 6 months for preventive tooth and gum care.

Store Chlorhexidine gluconate (Orogard) gluconate at room temperature away from moisture and heat.

Use sodium Sodium fluoride (Orogard) drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take sodium Sodium fluoride (Orogard) drops by mouth with or without food. Do not eat or drink dairy products within 1 hour before or 2 hours after taking sodium Sodium fluoride (Orogard) drops.
• Do not take an antacid that has aluminum, calcium, or magnesium in it for several hours after you take sodium Sodium fluoride (Orogard) drops.
• Use the dropper that comes with sodium Sodium fluoride (Orogard) drops to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.
• Certain brands of sodium Sodium fluoride (Orogard) drops should be mixed in juice or water before you take it. Contact your doctor or pharmacist if you are unsure if you should mix sodium Sodium fluoride (Orogard) drops in juice or water.
• Certain brands of sodium Sodium fluoride (Orogard) drops should be taken at bedtime after you brush your teeth unless your doctor tells you otherwise. Contact your doctor or pharmacist if you are unsure when to take sodium Sodium fluoride (Orogard) drops.
• If you miss a dose of sodium Sodium fluoride (Orogard) drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use sodium Sodium fluoride (Orogard) drops.

Use: Labeled Indications

Gingivitis:

Oral rinse: Antimicrobial dental rinse for gingivitis treatment

Periodontitis: Periodontal chip: Adjunctive therapy to scaling and root planning procedures to reduce pocket depth in patients with periodontitis

Off Label Uses

Medication-related osteonecrosis of the jaw (MRONJ), adjunctive therapy:

Oral rinse:

Based on a position paper by the American Association of Maxillofacial Surgeons (AAOMS), Chlorhexidine gluconate (Orogard) gluconate oral rinse is an effective and recommended adjunctive treatment strategy in the management of medication-related osteonecrosis of the jaw (MRONJ) (stage 1 and above [eg, patients with exposed and necrotic bone or fistulae that probes to bone]).

Oropharyngeal decontamination to reduce the risk of ventilator-associated or hospital-acquired pneumonia, Cardiac surgical patients:

Oral rinse:

Data from a prospective, randomized, double-blind, placebo-control trial and a prospective, randomized, case-controlled trial in patients undergoing coronary artery bypass grafting, valve, or other open heart surgical procedures who received Chlorhexidine gluconate (Orogard) gluconate 0.12% oral rinse during the perioperative period showed a decreased rate in hospital-acquired pneumonia. However, the trials used in both meta-analyses were heterogeneous and included patients in a variety of settings (eg, cardiothoracic, general ICU, mixed medical-surgical ICU, trauma ICU). The trials also displayed significant variability with Chlorhexidine gluconate (Orogard) treatment regimens. Chlorhexidine gluconate (Orogard) concentration varied from 0.12%, 0.2%, or 2% across studies. Frequency of administration, Chlorhexidine gluconate (Orogard) dosage form (oral rinse, gel, paste, foam), and technique of application also varied across studies. In the US, Chlorhexidine gluconate (Orogard) gluconate for use in the oral cavity is commercially available only as 0.12% solution. Additional trials may be necessary to further define the role of Chlorhexidine gluconate (Orogard) gluconate oral rinse in this condition.

This medication is used to prevent cavities. It makes teeth stronger and more resistant to decay caused by acid and bacteria. Talk to your dentist or doctor about the benefits and risks of this product.

This medication is not recommended for use in infants less than 6 months of age.

This medication is not recommended for use in areas where the Sodium fluoride (Orogard) content in the water supply is greater than 0.6 parts per million. See Notes section for more information.

How to use Sodium fluoride (Orogard)

Take this medication by mouth, usually once daily as directed by your doctor/dentist.

The dosage is based on your age and the Sodium fluoride (Orogard) content in your water supply.

If you are using the liquid form of this medication, measure the dose carefully using the specially marked medicine dropper that is provided. Drops may be swallowed directly, added to a small amount of juice, or mixed with a small amount of food such as applesauce. Do not mix with food containing milk or other dairy products.

If you are using the chewable form of this medication, chew or dissolve it in the mouth before swallowing so that the teeth will also absorb the Sodium fluoride (Orogard). If you are using the lozenge, place the lozenge in your mouth and allow it to dissolve. Take the chewable medication or lozenge at bedtime after brushing your teeth or as directed by your doctor/dentist. For best results, do not rinse your mouth, eat, or drink for 30 minutes after taking these forms of the medication.

Take this medication 1 hour apart from products that contain calcium, aluminum, or magnesium. Some examples include dairy products (such as milk, yogurt), antacids, laxatives, and vitamins/minerals. These products can bind with Sodium fluoride (Orogard), preventing its full absorption.

Use this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time each day.

Use: Labeled Indications

Trace element added to parenteral nutrition (PN) to prevent deficiency

See also:
What other drugs will affect Chlorhexidine gluconate (Orogard)?

Chlorhexidine gluconate (Orogard) is incompatible with the soap, and detergents containing anionic group (saponins, sodium lauryl sulfate, sodium carboxymethyl cellulose).

Chlorhexidine gluconate (Orogard) Pharmaniaga is compatible with any medication containing cationic group (cetrimonium bromide, benzalkonium chloride).

See also:
What other drugs will affect Sodium fluoride (Orogard)?

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

Before using this medication, tell your doctor/dentist or pharmacist of all prescription and nonprescription/herbal products you may use.

Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

See also:
What other drugs will affect Zinc chloride (Orogard)?

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to salicylic acid or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Young children may be at increased risk of unwanted effects because of increased absorption of salicylic acid through the skin. Also, young children may be more likely to get skin irritation from salicylic acid. Salicylic acid should not be applied to large areas of the body, used for long periods of time, or used under occlusive dressing (air-tight covering, such as kitchen plastic wrap) in infants and children. Salicylic acid should not be used in children younger than 2 years of age.

Geriatric

Elderly people are more likely to have age-related blood vessel disease. This may increase the chance of problems during treatment with salicylic acid.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

See also:
What are the possible side effects of Chlorhexidine gluconate (Orogard)?

The most common side effects associated with Chlorhexidine gluconate (Orogard) gluconate oral rinses are (1) an increase in staining of teeth and other oral surfaces, (2) an increase in calculus formation; and (3) an alteration in taste perception; see WARNINGS and PRECAUTIONS.

Oral irritation and local allergy-type symptoms have been spontaneously reported as side effects associated with the use of Chlorhexidine gluconate (Orogard) gluconate rinse.

The following oral mucosal side effects were reported during placebo-controlled adult clinical trials: aphthous ulcer, grossly obvious gingivitis, trauma, ulceration, erythema, desquamation, coated tongue, keratinization, geographic tongue, mucocele, and short frenum. Each occurred at a frequency of less than 1.0%.

Among post marketing reports, the most frequently reported oral mucosal symptoms associated with Chlorhexidine gluconate (Orogard) gluconate oral rinse are stomatitis, gingivitis, glossitis, ulcer, dry mouth, hypesthesia, glossal edema, and paresthesia.

Minor irritation and superficial desquamation of the oral mucosa have been noted in patients using Chlorhexidine gluconate (Orogard) gluconate oral rinse.

There have been cases of parotid gland swelling and inflammation of the salivary glands (sialadenitis) reported in patients using Chlorhexidine gluconate (Orogard) gluconate oral rinse.

See also:
What are the possible side effects of Sodium fluoride (Orogard)?

Applies to Sodium fluoride (Orogard) topical: cream, gel/jelly, liquid, paste, solution, suspension, tablet chewable

Along with its needed effects, Sodium fluoride (Orogard) topical (the active ingredient contained in Sodium fluoride (Orogard)) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking Sodium fluoride (Orogard) topical:

Sodium Sodium fluoride (Orogard) in drinking water or taken as a supplement does not usually cause any side effects. However, taking an overdose of Sodium fluoride (Orogard) may cause serious problems.

• Sores in the mouth and on the lips (rare)

Stop taking Sodium fluoride (Orogard) topical and get emergency help immediately if any of the following effects occur:

• Black, tarry stools
• bloody vomit
• diarrhea
• drowsiness
• faintness
• increased watering of the mouth
• nausea or vomiting
• shallow breathing
• stomach cramps or pain
• tremors
• unusual excitement
• watery eyes
• weakness

Check with your doctor as soon as possible if any of the following side effects occur while taking Sodium fluoride (Orogard) topical:

• Pain and aching of bones
• stiffness
• white, brown, or black discoloration of the teeth—occurs only during periods of tooth development in children

See also:
What are the possible side effects of Zinc chloride (Orogard)?

Using salicylic acid with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acenocoumarol

Anisindione

Ardeparin

Certoparin

Dalteparin

Danaparoid

Dicumarol

Enoxaparin

Nadroparin

Parnaparin

Phenindione

Phenprocoumon

Probenecid

Reviparin

Tamarind

Tinzaparin

Warfarin