Composición:
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Usado en tratamiento:
Revisión médica por Militian Inessa Mesropovna Última actualización de farmacia el 05.04.2022
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Los 20 mejores medicamentos con los mismos ingredientes:
POSSIBLE SIDE EFFECTS
Like all medicines, It's a medicine this can lead to adverse consequences, even if not all people suffer from them.
Since these reactions are reported voluntarily, their frequency is not exactly known:
-Allergic reactions, hypersensitivity reactions with symptoms that may be respiratory (such as wheezing), mild to moderate skin reactions, symptoms in the digestive tract and/or cardiovascular system have been reported. symptoms may include rash (rash), itching, urticaria (the appearance of reddish scars on the skin is usually itchy), rapid edema of the skin and mucous membranes (angioedema) and cardiovascular and respiratory difficulties.
If an allergic reaction occurs, you should stop treatment and contact a medical professional.
- Mild gastrointestinal reactions, such as nausea, vomiting, diarrhea, abdominal and gastrointestinal pain .
- Contact dermatitis in predisposed patients
The message on the adverse consequences of
If you are experiencing any side effects, consult your doctor or pharmacist, even if it is possible side effects that do not appear in this brochure You can also contact them directly through Spain and the drug delivery system, husband-to-man: www.notificaRAM.es. Cuba o has little impact, you can contribute to providing more information about the safety of this drug.
POSSIBLE SIDE EFFECTS
Like all medicines, It's a medicine this can lead to adverse consequences, even if not all people suffer from them.
Since these reactions are reported voluntarily, their frequency is not exactly known:
-Allergic reactions, hypersensitivity reactions with symptoms that may be respiratory (such as wheezing), mild to moderate skin reactions, symptoms in the digestive tract and/or cardiovascular system have been reported. symptoms may include rash (rash), itching, urticaria (the appearance of reddish scars on the skin is usually itchy), rapid edema of the skin and mucous membranes (angioedema) and cardiovascular and respiratory difficulties.
If an allergic reaction occurs, you should stop treatment and contact a medical professional.
- Mild gastrointestinal reactions, such as nausea, vomiting, diarrhea, abdominal and gastrointestinal pain .
- Contact dermatitis in predisposed patients
The message on the adverse consequences of
If you are experiencing any side effects, consult your doctor or pharmacist, even if it is possible side effects that do not appear in this brochure You can also contact them directly through Spain and the drug delivery system, husband-to-man: www.notificaRAM.es. Cuba o has little impact, you can contribute to providing more information about the safety of this drug.
POSSIBLE SIDE EFFECTS
Like all medicines, It's a medicine this can lead to adverse consequences, even if not all people suffer from them.
Since these reactions are reported voluntarily, their frequency is not exactly known:
-Allergic reactions, hypersensitivity reactions with symptoms that may be respiratory (such as wheezing), mild to moderate skin reactions, symptoms in the digestive tract and/or cardiovascular system have been reported. symptoms may include rash (rash), itching, urticaria (the appearance of reddish scars on the skin is usually itchy), rapid edema of the skin and mucous membranes (angioedema) and cardiovascular and respiratory difficulties.
If an allergic reaction occurs, you should stop treatment and contact a medical professional.
- Mild gastrointestinal reactions, such as nausea, vomiting, diarrhea, abdominal and gastrointestinal pain .
- Contact dermatitis in predisposed patients
The message on the adverse consequences of
If you are experiencing any side effects, consult your doctor or pharmacist, even if it is possible side effects that do not appear in this brochure You can also contact them directly through Spain and the drug delivery system, husband-to-man: www.notificaRAM.es. Cuba o has little impact, you can contribute to providing more information about the safety of this drug.
POSSIBLE SIDE EFFECTS
Like all medicines, It's a medicine this can lead to adverse consequences, even if not all people suffer from them.
Since these reactions are reported voluntarily, their frequency is not exactly known:
-Allergic reactions, hypersensitivity reactions with symptoms that may be respiratory (such as wheezing), mild to moderate skin reactions, symptoms in the digestive tract and/or cardiovascular system have been reported. symptoms may include rash (rash), itching, urticaria (the appearance of reddish scars on the skin is usually itchy), rapid edema of the skin and mucous membranes (angioedema) and cardiovascular and respiratory difficulties.
If an allergic reaction occurs, you should stop treatment and contact a medical professional.
- Mild gastrointestinal reactions, such as nausea, vomiting, diarrhea, abdominal and gastrointestinal pain .
- Contact dermatitis in predisposed patients
The message on the adverse consequences of
If you are experiencing any side effects, consult your doctor or pharmacist, even if it is possible side effects that do not appear in this brochure You can also contact them directly through Spain and the drug delivery system, husband-to-man: www.notificaRAM.es. Cuba o has little impact, you can contribute to providing more information about the safety of this drug.
POSSIBLE SIDE EFFECTS
Like all medicines, It's a medicine this can lead to adverse consequences, even if not all people suffer from them.
Since these reactions are reported voluntarily, their frequency is not exactly known:
-Allergic reactions, hypersensitivity reactions with symptoms that may be respiratory (such as wheezing), mild to moderate skin reactions, symptoms in the digestive tract and/or cardiovascular system have been reported. symptoms may include rash (rash), itching, urticaria (the appearance of reddish scars on the skin is usually itchy), rapid edema of the skin and mucous membranes (angioedema) and cardiovascular and respiratory difficulties.
If an allergic reaction occurs, you should stop treatment and contact a medical professional.
- Mild gastrointestinal reactions, such as nausea, vomiting, diarrhea, abdominal and gastrointestinal pain .
- Contact dermatitis in predisposed patients
The message on the adverse consequences of
If you are experiencing any side effects, consult your doctor or pharmacist, even if it is possible side effects that do not appear in this brochure You can also contact them directly through Spain and the drug delivery system, husband-to-man: www.notificaRAM.es. Cuba o has little impact, you can contribute to providing more information about the safety of this drug.
ADVERTENCIA
La depresión hematopoyética es la toxicidad más común con DTlC-Dome e involucra principalmente a los leucocitos y las plaquetas, aunque a veces puede ocurrir anemia. La leucopenia y la trombocitopenia pueden ser lo suficientemente graves como para causar la muerte. La posible depresión de la médula ósea requiere un control cuidadoso de los glóbulos blancos, los glóbulos rojos y los niveles de plaquetas. La toxicidad hematopoyética puede justificar la suspensión temporal o el cese del tratamiento con DTlC-Dome.
Se ha notificado toxicidad hepática acompañada de trombosis venosa hepática y necrosis hepatocelular que provoca la muerte. La incidencia de tales reacciones ha sido baja, aproximadamente el 0,01% de los pacientes tratados. Esta toxicidad se ha observado principalmente cuando Dacarbazine Hospira-Dome (dacarbazine) se ha administrado concomitantemente con otros fármacos antineoplásicos, sin embargo, también se ha notificado en algunos pacientes tratados con DTlC-Dome solos.
La anafilaxia puede ocurrir después de la administración de DTlC-Dome.
PRECAUCIONES
La hospitalización no siempre es necesaria, pero la capacidad de estudio de laboratorio adecuada debe estar disponible. La extravasación del medicamento por vía subcutánea durante la administración intravenosa puede provocar daño tisular y dolor intenso. El dolor local, la sensación de ardor y la irritación en el sitio del inyectón pueden aliviarse con paquetes calientes aplicados localmente.
La carcinogenicidad de DTlC se estudió en ratas y ratones. Las lesiones endocárdicas proliferativas, incluidos fibrosarcomas y sarcomas, fueron inducidas por DTlC en ratas. En ratones, la administración de Dacarbazine Hospira dio lugar a la inducción de angiosarcomas del bazo.
Embarazo Categoría C. Dacarbazina Hospira-Dome (dacarbazina) ha demostrado ser teratogénico en ratas cuando se administra en dosis 20 veces la dosis diaria en humanos el día 12 de gestación. DTlC cuando se administró en 10 veces la dosis diaria en humanos a ratas macho (dos veces por semana durante 9 semanas) no afectó a la libido masculina, aunque las ratas hembra apareadas en ratas macho tuvieron una mayor incidencia de reabsorción que los controles. En conejos, la dosis diaria de DTlC 7 veces la dosis diaria en humanos administrada en los días 6 a 15 de gestación dio como resultado anomalías esqueléticas fetales. No hay estudios adecuados y bien controlados en mujeres embarazadas. DTlC-Dome debe usarse durante el embarazo solo si el beneficio potencial justifica el riesgo potencial para el feto
No se sabe si este medicamento se excreta en la leche humana. Debido a que muchos fármacos se excretan en la leche humana y debido al potencial de tumorigenicidad mostrado para Dacarbazine Hospira-Dome (dacarbazine) en estudios en animales, se debe tomar una decisión si interrumpir la lactancia o interrumpir el medicamento, teniendo en cuenta la importancia del medicamento para la madre.
POSSIBLE SIDE EFFECTS
Like all medicines, It's a medicine this can lead to adverse consequences, even if not all people suffer from them.
Since these reactions are reported voluntarily, their frequency is not exactly known:
-Allergic reactions, hypersensitivity reactions with symptoms that may be respiratory (such as wheezing), mild to moderate skin reactions, symptoms in the digestive tract and/or cardiovascular system have been reported. symptoms may include rash (rash), itching, urticaria (the appearance of reddish scars on the skin is usually itchy), rapid edema of the skin and mucous membranes (angioedema) and cardiovascular and respiratory difficulties.
If an allergic reaction occurs, you should stop treatment and contact a medical professional.
- Mild gastrointestinal reactions, such as nausea, vomiting, diarrhea, abdominal and gastrointestinal pain .
- Contact dermatitis in predisposed patients
The message on the adverse consequences of
If you are experiencing any side effects, consult your doctor or pharmacist, even if it is possible side effects that do not appear in this brochure You can also contact them directly through Spain and the drug delivery system, husband-to-man: www.notificaRAM.es. Cuba o has little impact, you can contribute to providing more information about the safety of this drug.
Dar tratamiento de apoyo y controlar el recuento de células sanguíneas.
POSSIBLE SIDE EFFECTS
Like all medicines, It's a medicine this can lead to adverse consequences, even if not all people suffer from them.
Since these reactions are reported voluntarily, their frequency is not exactly known:
-Allergic reactions, hypersensitivity reactions with symptoms that may be respiratory (such as wheezing), mild to moderate skin reactions, symptoms in the digestive tract and/or cardiovascular system have been reported. symptoms may include rash (rash), itching, urticaria (the appearance of reddish scars on the skin is usually itchy), rapid edema of the skin and mucous membranes (angioedema) and cardiovascular and respiratory difficulties.
If an allergic reaction occurs, you should stop treatment and contact a medical professional.
- Mild gastrointestinal reactions, such as nausea, vomiting, diarrhea, abdominal and gastrointestinal pain .
- Contact dermatitis in predisposed patients
The message on the adverse consequences of
If you are experiencing any side effects, consult your doctor or pharmacist, even if it is possible side effects that do not appear in this brochure You can also contact them directly through Spain and the drug delivery system, husband-to-man: www.notificaRAM.es. Cuba o has little impact, you can contribute to providing more information about the safety of this drug.
POSSIBLE SIDE EFFECTS
Like all medicines, It's a medicine this can lead to adverse consequences, even if not all people suffer from them.
Since these reactions are reported voluntarily, their frequency is not exactly known:
-Allergic reactions, hypersensitivity reactions with symptoms that may be respiratory (such as wheezing), mild to moderate skin reactions, symptoms in the digestive tract and/or cardiovascular system have been reported. symptoms may include rash (rash), itching, urticaria (the appearance of reddish scars on the skin is usually itchy), rapid edema of the skin and mucous membranes (angioedema) and cardiovascular and respiratory difficulties.
If an allergic reaction occurs, you should stop treatment and contact a medical professional.
- Mild gastrointestinal reactions, such as nausea, vomiting, diarrhea, abdominal and gastrointestinal pain .
- Contact dermatitis in predisposed patients
The message on the adverse consequences of
If you are experiencing any side effects, consult your doctor or pharmacist, even if it is possible side effects that do not appear in this brochure You can also contact them directly through Spain and the drug delivery system, husband-to-man: www.notificaRAM.es. Cuba o has little impact, you can contribute to providing more information about the safety of this drug.
POSSIBLE SIDE EFFECTS
Like all medicines, It's a medicine this can lead to adverse consequences, even if not all people suffer from them.
Since these reactions are reported voluntarily, their frequency is not exactly known:
-Allergic reactions, hypersensitivity reactions with symptoms that may be respiratory (such as wheezing), mild to moderate skin reactions, symptoms in the digestive tract and/or cardiovascular system have been reported. symptoms may include rash (rash), itching, urticaria (the appearance of reddish scars on the skin is usually itchy), rapid edema of the skin and mucous membranes (angioedema) and cardiovascular and respiratory difficulties.
If an allergic reaction occurs, you should stop treatment and contact a medical professional.
- Mild gastrointestinal reactions, such as nausea, vomiting, diarrhea, abdominal and gastrointestinal pain .
- Contact dermatitis in predisposed patients
The message on the adverse consequences of
If you are experiencing any side effects, consult your doctor or pharmacist, even if it is possible side effects that do not appear in this brochure You can also contact them directly through Spain and the drug delivery system, husband-to-man: www.notificaRAM.es. Cuba o has little impact, you can contribute to providing more information about the safety of this drug.
