Componentes:
Método de ação:
Opção de tratamento:
Medicamente revisado por Oliinyk Elizabeth Ivanovna, Farmácia Última atualização em 28.03.2022
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20 principais medicamentos com os mesmos componentes:
20 principais medicamentos com os mesmos tratamentos:
- Hypertension
- Chronic stable angina pectoris
- Vasospastic (Prinzmetal's) angina
Posology
Adults
For both hypertension and angina the usual initial dose is 5 mg Adipin once daily which may be increased to a maximum dose of 10 mg depending on the individual patient's response.
In hypertensive patients, Adipin has been used in combination with a thiazide diuretic, alpha blocker, beta blocker, or an angiotensin converting enzyme inhibitor. For angina, Adipin may be used as monotherapy or in combination with other antianginal medicinal products in patients with angina that is refractory to nitrates and/or to adequate doses of beta blockers.
No dose adjustment of Adipin is required upon concomitant administration of thiazide diuretics, beta blockers, and angiotensin-converting enzyme inhibitors.
Paediatric population
Use in children and adolescents (less than 18 years of age)
Not recommended.
Special populations
Use in the elderly
Adipin, used at similar doses in elderly or younger patients, is equally well tolerated. Therefore normal dosage regimens are recommended in the elderly, but increase of the dosage should take palce with care.
Patients with hepatic impairment
Dosage recommendations have not been established in patients with mild to moderate hepatic impairment; therefore dose selection should be cautious and should start at the lower end of the dosing range. The pharmacokinetics of Adipin have not been studied in severe hepatic impairment. Adipin should be initiated at the lowest dose and titrated slowly in patients with severe hepatic impairment.
Patients with renal impairment
Changes in Adipin plasma concentrations are not correlated with degree of renal impairment, therefore the normal dosage is recommended. Adipin is not dialysable.
Method of administration
Tablet for oral administration.