Tusco

The d-isomer of the codeine analog of levorphanol. Tusco shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (receptors, N-methyl-D-aspartate) and acts as a non-competitive channel blocker. It is one of the widely used antitussives, and is also used to study the involvement of glutamate receptors in neurotoxicity.

se usa para tratar síntomas causados por el resfriado común, la gripe, las alergias, la fiebre del heno u otras enfermedades respiratorias (p. ej., sinusitis, bronquitis). Tusco es un supresor de la tos que afecta a cierta parte del cerebro (centro de la tos), lo que reduce la necesidad de toser. Los descongestionantes ayudan a aliviar los síntomas cutáneos congestionados. Los antihistamínicos alivian los ojos llorosos, picazón en los ojos / nariz / garganta, secreción nasal y estornudos.

Tusco es un supresor de la tos. Afecta las señales en el cerebro que desencadenan el reflejo de la tos.

Tusco se usa para tratar la tos.

Tusco no tratará una tos causada por fumar, asma o enfisema.

Tusco también se puede usar para fines no enumerados en esta guía de medicamentos.

Formas de dosificación

Información excipiente presentada cuando esté disponible (limitada, particularmente para genéricos); consultar etiquetado específico del producto. [DSC] = Producto descontinuado

Cápsula,

Oral, como bromhidrato:

Tos Robafen: 15 mg [contiene fcf azul brillante (fd & c blue # 1), fd & c red # 40]

Robitussin Lingering CoughGels: 15 mg [contiene fcf azul brillante (fd & c azul # 1), fd & c rojo # 40, polietilenglicol, propilenglicol]

Gel,

Oral, como bromhidrato:

Tos ElixSure: 7,5 mg / 5 ml (120 ml) [sin alcohol; contiene carbómero 934p, propilenglicol, propilparabeno; sabor a chicle]

Líquido,

Oral, como bromhidrato:

Tos de Buckleys: 12.5 mg / 5 ml (118 ml) [sin alcohol, sin azúcar; contiene butilparabeno, mentol, propilparabeno, sacarina sódica]

Fórmula de tos de Little Colds: 7.5 mg / ml (30 ml) [sin alcohol, sin colorantes, sin sacarina; contiene benzoato de sodio; sabor a uva]

PediaCare Childrens Long-Act: 7.5 mg / 5 ml (118 ml) [contiene fcf azul brillante (fd & c blue # 1), sacarina sódica, benzoato de sodio]

Robitussin Lingering LA Tos: 15 mg / 5 ml (118 ml [DSC]) [contiene alcohol, usp, fd & c red # 40, mentol, sacarina sódica, benzoato de sodio]

Tusco: 10 mg / 5 ml (480 ml [DSC], 3780 ml [DSC]) [sin alcohol, sin colorantes, sin fructosa, sin sodio, sin sorbitol, sin azúcar]

Tos triamínica de acción prolongada: 7,5 mg / 5 ml (118 ml) [sin alcohol, sin colorantes, sin pseudoefedrina; contiene ácido benzoico, propilenglicol]

Lozenge, Boca / Garganta, como bromhidrato :

Hold: 5 mg (10 ea)

Hold: 5 mg (10 ea) [sabor a cereza]

Supresor de la tos tropical: 7,5 mg (1 ea [DSC])

Strip ,

Oral, como bromhidrato:

Tos triamínica de acción prolongada: 7,5 mg (14 ea, 16 ea) [contiene alcohol, usp, fd & c rojo # 40; sabor a cereza]

Tos triamínica de acción prolongada: 7,5 mg (14 ea) [contiene alcohol, usp, fd & c rojo # 40, alcohol isopropílico]

Suspensión Lanzamiento Extendido,

Oral:

Tos DM: Tusco polistirex [equivalente a Tusco 30 mg / 5 ml] (89 ml) [sin alcohol; contiene fd & c amarillo # 10 lago de aluminio, metilparabeno, polisorbato 80, propilparabeno, metabisulfito de sodio; sabor a naranja]

Tusco: Tusco polistirex [equivalente a Tusco 30 mg / 5 ml] (89 ml, 148 ml) [sin alcohol; contiene azul brillante fcf (fd & c azul # 1), edta disódico, metilparabeno, polietilenglicol, polisorbato 80, propilenglicol, propilpar

Tusco: Tusco polistirex [equivalente a Tusco 30 mg / 5 ml] (89 ml, 148 ml) [sin alcohol; contiene edetato disódico, fd & c amarillo # 6 (amarillo al atardecer), metilparabeno, polietilenglicol, polisorbato 80, propilenglicol

Tosco Niños: Tusco polistirex [equivalente a Tusco 30 mg / 5 ml] (89 ml, 148 ml) [sin alcohol; contiene fcf azul brillante (fd & c blue # 1), edetato disódico, metilparabeno, polietilenglicol, polisorbato 80, propilenglicol

Tosco Childrens: Tusco polistirex [equivalente a Tusco 30 mg / 5 ml] (89 ml, 148 ml) [sin alcohol; contiene edetato disódico, fd & c amarillo # 6 (amarillo al atardecer), metilparabeno, polietilenglicol, polisorbato 80, propilenglicol

GoodSense Cough DM: Tusco polistirex [equivalente a Tusco 30 mg / 5 ml] (148 ml) [sin alcohol, sin gluten; contiene fd & c amarillo # 10 lago de aluminio, metilparabeno, polisorbato 80, propilparabeno, metabisulfito de sodio]

GoodSense Cough DM Childrens: Tusco polistirex [equivalente a Tusco 30 mg / 5 ml] (89 ml, 148 ml) [sin alcohol, sin gluten; contiene fd & c amarillo # 10 lago de aluminio, metilparabeno, polisorbato 80, propilparabeno, metabisulfito de sodio]

Robitussin 12 Hour Cough: Tusco polistirex [equivalente a Tusco 30 mg / 5 ml] (89 ml) [sin alcohol; contiene fcf azul brillante (fd & c azul # 1), metilparabeno, polisorbato 80, propilparabeno, metabisulfito de sodio]

Robitussin 12 Hour Cough: Tusco polistirex [equivalente a Tusco 30 mg / 5 ml] (89 ml) [sin alcohol; contiene fd & c amarillo # 10 (amarillo de quinolina), metilparabeno, polisorbato 80, propilparabeno, metabisulfito de sodio]

Robitussin 12 horas tos

Niño: Tusco polistirex [equivalente a Tusco 30 mg / 5 ml] (89 ml) [sin alcohol; contiene azul brillante fcf (fd & c azul # 1), metilparabeno, polisorbato 80, propilparabeno, metabisulfito de sodio]

Genérico: Tusco polistirex [equivalente a Tusco 30 mg / 5 ml] (89 ml)

Jarabe,

Oral, como bromhidrato:

Creomulsión

Adulto: 20 mg / 15 ml (118 ml [DSC])

Creomulsión para niños: 5 mg / 5 ml (118 ml [DSC]) [sabor a cereza]

Robitussin Childrens Cough LA: 7.5 mg / 5 ml (118 ml) [sin alcohol; contiene fd & c red # 40, propilenglicol, sacarina sódica, benzoato de sodio; sabor a ponche de frutas]

Silphen DM Cough: 10 mg / 5 ml (118 ml) [contiene alcohol, usp; sabor a fresa]

Tos triamínica de acción prolongada: 7,5 mg / 5 ml (118 ml [DSC]) [sin alcohol, sin colorantes; contiene ácido benzoico, edetato disódico, propilenglicol]

Dosificación: Adulto

Supresor de la tos:

Oral: 10 a 20 mg cada 4 horas

Dosificación: geriátrica

Consulte la dosificación de adultos.

Dosificación: pediátrica

Nota: Seguridad y eficacia para el uso de productos para la tos y el resfriado en bebés y niños pequeños limitados; AAP advierte contra el uso de estos productos para enfermedades respiratorias en bebés y niños pequeños (AAP 2018; FDA 2017).

Supresor de la tos:

Oral:

Jarabe oral (liberación inmediata) :

Niños de 2 a <6 años: 5 mg cada 4 horas según sea necesario; No exceda de 6 dosis en 24 horas.

Niños de 6 a <12 años: 10 mg cada 4 horas según sea necesario; No exceda de 6 dosis en 24 horas.

Niños ≥12 años y adolescentes: 20 mg cada 4 horas según sea necesario; No exceda de 6 dosis en 24 horas.

Líquido de acción prolongada: niños ≥12 años y adolescentes: 30 mg cada 6 a 8 horas según sea necesario; No exceda 4 dosis en 24 horas.

Cápsula oral: niños ≥12 años y adolescentes: 30 mg cada 6 a 8 horas según sea necesario; No exceda 4 dosis en 24 horas.

Suspensión de liberación prolongada (Tusco polistirex) :

Niños de 4 a <6 años: 15 mg cada 12 horas según sea necesario; No exceda los 30 mg en 24 horas.

Niños de 6 a <12 años: 30 mg cada 12 horas según sea necesario; no exceda de 60 mg en 24 horas.

Niños ≥12 años y adolescentes: 60 mg cada 12 horas según sea necesario; No exceda 120 mg en 24 horas.

Ver también:
¿Cuál es la información más importante que debo saber sobre Tusco??

No use Tusco si ha usado un inhibidor de la MAO como isocarboxazida (Marplan), fenelzina (Nardil), rasagilina (Azilect), selegilina (Eldepryl, Emsam) o tranilcipromina (Parnate) en los últimos 14 días. Pueden producirse efectos secundarios graves y potencialmente mortales si toma Tusco antes de que el inhibidor de la MAO se haya despejado de su cuerpo.

No use ningún otro medicamento de venta libre para la tos, el resfriado o la alergia sin consultar primero a su médico o farmacéutico. Si toma ciertos productos juntos, puede tomar accidentalmente demasiado de uno o más tipos de medicamentos. Lea la etiqueta de cualquier otro medicamento que esté usando para ver si contiene Dextrometorfano.

Use Tusco orally disintegrating strips as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Tusco orally disintegrating strips by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
• Do not remove the strip from the pouch until you are ready to take Tusco orally disintegrating strips. Be sure that your hands are dry when you touch the strip.
• Remove the strip from the pouch and place it onto the tongue. The strip dissolves quickly and can be swallowed with saliva. It may be taken with or without water.
• Use the strip right away after you open the pouch. Do not store it for future use.
• If you miss a dose of Tusco orally disintegrating strips and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Tusco orally disintegrating strips.

This medication is used for temporary relief of coughs without phlegm that are caused by certain infections of the air passages (e.g., sinusitis, common cold). This product should not usually be used for an ongoing cough from smoking or long-term breathing problems (e.g., chronic bronchitis, emphysema) unless directed by your doctor. This product contains Dextromethorphan. It is a cough suppressant that works by decreasing the feeling of needing to cough.

Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Therefore, do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. Ask your doctor or pharmacist for more details about using your product safely.

These products do not cure or shorten the length of the common cold and may cause serious side effects. To decrease the risk for serious side effects, carefully follow all dosage directions. Do not use this product to make a child sleepy. Do not give other cough-and-cold medication that might contain the same or similar ingredients. Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray).

How to use Tusco

Take this medication by mouth, usually every 4 to 12 hours as needed or as directed by your doctor. If stomach upset occurs, take with food or milk. Use a medication-measuring device to measure your dose of liquid medication. Do not use a household spoon because you may not get the correct dose. If you are taking a suspension, shake the product well before measuring out your dose.

Dosage is based on the product you are taking and your age, medical condition, and response to treatment. If you are using this medication for self-treatment (without a prescription from your doctor), follow the specific dosing instructions on the packaging to find the correct dose for your age.

If your doctor directs you to take this medication daily, take it regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

Improper use of this medication (abuse) may result in serious harm (e.g., brain damage, seizure, death). Do not increase your dose, take it more frequently, or use it for a longer time than prescribed. Properly stop the medication when so directed.

Tell your doctor if your symptoms persist or worsen after more than 1 week or if you also have fever, chills, headache, or rash. These may be signs of a more serious condition.

See also:
What other drugs will affect Tusco?

MAO inhibitors (including furazolidone, procarbazine, selegiline) when administered simultaneous with Tusco may cause adrenergic crisis, collapse, coma, dizziness, agitation, increased blood pressure, hyperpyrexia, intracranial hemorrhage, lethargy, nausea, cramps, tremor. In combination with tricyclic antidepressants (amitriptyline, etc.) Tusco Lafayette Pharmaceutical Laboratory may appeal serotonin syndrome and possible subsequent death. Amiodarone, fluoxetine, quinidine, inhibiting system cytochrome P450, may increase the drug concentration in the blood. Tobacco smoke can lead to increased secretion of glands in the background of inhibition of cough reflex. Some inhibitors of CYP450 (such as quinidine) increase and extended effects of this medicine.

See also:
What are the possible side effects of Tusco?

Applies to Tusco: oral capsule, oral capsule liquid filled, oral elixir, oral liquid, oral lozenge/troche, oral solution, oral suspension, oral suspension extended release, oral syrup, oral tablet

In addition to its needed effects, some unwanted effects may be caused by Tusco (the active ingredient contained in Tusco HBr Adult Formula). In the event that any of these side effects do occur, they may require medical attention.

Severity: Moderate

If any of the following side effects occur while taking Tusco, check with your doctor or nurse as soon as possible:

Symptoms of overdose:

• Blurred vision
• confusion
• difficulty in urination
• drowsiness or dizziness
• nausea or vomiting (severe)
• shakiness and unsteady walk
• slowed breathing
• unusual excitement, nervousness, restlessness, or irritability (severe)

Minor Side Effects

Some of the side effects that can occur with Tusco may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common or rare:

• Confusion
• constipation
• dizziness (mild)
• drowsiness (mild)
• headache
• nausea or vomiting
• stomach pain