Composition:
Application:
Utilisé dans le traitement:
Examiné médicalement par Fedorchenko Olga Valeryevna, Pharmacie Dernière mise à jour le 13.03.2022
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Adco-Dapamax hemihydrate tablets are indicated for the oral treatment of essential hypertension.
Adco-Dapamax hemihydrate tablets may be used as sole therapy or combined with other antihypertensive agents.
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Posology
Adults
The dosage is one tablet, containing 2.5 mg Adco-Dapamax hemihydrate, daily to be taken in the morning.
Patients with renal failure
In severe renal failure (creatinine clearance below 30 ml/min), treatment is contraindicated. Thiazide and related diuretics are fully effective only when renal function is normal or only minimally impaired.
Older people
In the older people, the plasma creatinine must be adjusted in relation to age, weight and gender. Older people can be treated with Adco-Dapamax when renal function is normal or only minimally impaired.
Patients with hepatic impairment
In severe hepatic impairment, treatment is contraindicated.
Paediatric population
Adco-Dapamax is not recommended for use in children and adolescents due to a lack of data on safety and efficacy.
The action of Adco-Dapamax is progressive and the reduction in blood pressure may continue and not reach a maximum until several months after the start of therapy. A larger dose than 2.5 mg Adco-Dapamax daily is not recommended as there is no appreciable additional antihypertensive effect but a diuretic effect may become apparent.
If a single daily tablet of Adco-Dapamax does not achieve a sufficient reduction in blood pressure, another antihypertensive agent may be added; those which have been used in combination with Adco-Dapamax include beta-blockers, ACE inhibitors, methyldopa, clonidine and other adrenergic blocking agents. The co-administration of Adco-Dapamax with diuretics may cause hypokalaemia and, therefore, is not recommended.
There is no evidence of rebound hypertension on withdrawal of Adco-Dapamax.
Method of administration
Adco-Dapamax tablets are for oral administration only.