Components:
Method of action:
Treatment option:
Medically reviewed by Fedorchenko Olga Valeryevna, PharmD. Last updated on 26.06.2023
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Absorption
The mean absorption of calcitriol is estimated at around 10%. Following absorption, both unchanged calcitriol and metabolites have been demonstrated in plasma. The effect of the metabolites on calcium homeostasis is negligible. In most patients, circulating levels of exogenous calcitriol are below the level of detection (2pg/ml).
Distribution
In clinical trials, no relevant increase in plasma calcitriol levels after treatment of large body surface areas of up to 6000 cm2 (35% body surface area) was noted.
Liquid paraffin, white soft paraffin and alpha- tocopherol.
There are no relevant data on the compatibility of Silkis with other medicinal products.).
In the absence of compatibility studies, this medicinal product must not be mixed with other medicinal products.
3 years
Shelf life after first opening: 8 weeks.
No special precautions for storage.
The product is packaged in collapsible aluminium tubes coated internally with an epoxy - phenolic resin and fitted with a white high density polyethylene or polypropylene screw cap.
Tubes contain either 15, 30 or 100g of ointment.
Not all pack sizes may be marketed.
Dispose of the medication in accordance with local regulations for medical waste.
Galderma (UK) Limited
Meridien House
69-71 Clarendon Road
Watford
Herts
WD17 1DS
UK
PL 10590/0047
10.07.1995 / 09.02.2004
April 2017
