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Smofkabiven

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Name of the medicinal product
Therapeutic indications
Dosage (Posology) and method of administration
Contraindications
Interaction with other medicinal products and other forms of interaction
Undesirable effects

Components:

Alanine, Arginine, Glycine, Histidine, Methionine, Mg, Nitrogen, Olive Oil, Soya Oil, Taurine, Threonine, Tryptophan, Tyrosine, Lysine, Isoleucine, Leucine, Lysine Acetate, Phenylalanine, Valine, Proline, Serine, Fish Oil, Medium-chain Triglycerides, Lipids, Ca, Zn, Amino Acids, Zn Sulfate Heptahydrate, K, Kcl, Cl, Acetate, Glucose, Sulphate, Phosphate, Glucose Monohydrate, Mg Sulfate Heptahydrate, Se, Refined Olive Oil, Combinations, Na Glycerophosphate Hydrate, Na Acetate Trihydrate, Huile Poisson, Refined Soya Bean Oil, Total:, Cacl2 Dihydrate

Medically reviewed by Oliinyk Elizabeth Ivanovna, PharmD. Last updated on 26.03.2022

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Name of the medicinal product
Smofkabiven
Therapeutic indications
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.

Parenteral nutrition for adults when oral or enteral nutrition is impossible, insufficient or contraindicated.

Dosage (Posology) and method of administration

Individualized dosage. IV infusion into central vein SmofKabiven Central 13-31 mL/kg body wt/day. Max: 35 mL/kg body wt/day. Infusion rate should not exceed 2 mL/kg body wt/hr for 14-24 hr. IV infusion into peripheral/central vein SmofKabiven Peripheral 20-40 mL/kg body wt/day. Max: 40 mL/kg body wt/day. Infusion rate should not exceed 3 mL/kg body wt/hr for 14-24 hr.

Contraindications

Hypersensitivity to fish, egg, soya or peanut protein. Severe hyperlipidemia, hepatic or renal (w/o access to hemofiltration or dialysis) insufficiency & blood coagulation disorders. Congenital errors of amino acid metabolism. Acute shock, uncontrolled hyperglycemia, pathologically elevated serum electrolyte levels. Acute pulmonary edema, hyperhydration, decompensated cardiac insufficiency, hemophagocytotic syndrome. Unstable conditions eg severe post-traumatic conditions, uncompensated DM, acute MI, stroke, embolism, metabolic acidosis, severe sepsis, hypotonic dehydration, hyperosmolar coma. Infant & childn ≤11 yr.


Interaction with other medicinal products and other forms of interaction

Insulin, heparin.

Undesirable effects

Slight increase in body temp. Thrombophlebitis (SmofKabiven Peripheral).

References:

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