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Medically reviewed by Militian Inessa Mesropovna, PharmD. Last updated on 26.06.2023

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A histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during pregnancy and radiation sickness. [PubChem]
Siguran is an antihistamine and anticholinergic. It works by blocking a chemical messenger in the brain, which helps to reduce or prevent vomiting.
Siguran is used to treat or prevent nausea, vomiting, and dizziness caused by motion sickness. It is also used for vertigo (or dizziness) caused by certain inner ear problems.
Siguran is an antihistamine that reduces the effects of natural chemical histamine in the body.
Siguran is used to treat or prevent nausea, vomiting, and dizziness caused by motion sickness. Siguran is also used to treat symptoms of vertigo (dizziness or spinning sensation) caused by disease that affects your inner ear.
Siguran may also be used for purposes not listed in this medication guide.
Usual Adult Dose for Nausea/Vomiting:
25 to 50 mg orally once a day as needed.
Usual Adult Dose for Vertigo:
25 mg orally 1 to 4 times a day or 50 mg orally twice a day.
Usual Adult Dose for Motion Sickness:
25 to 50 mg orally once a day as needed. Siguran should be administered one hour prior to travel and continued for the duration of exposure.
Do not exceed 50 mg in 24 hours.
Usual Pediatric Dose for Nausea/Vomiting:
> 12 years: 25 to 50 mg orally once a day as needed.
Usual Pediatric Dose for Vertigo:
> 12 years: 25 mg orally 1 to 4 times a day or 50 mg orally twice a day.
Usual Pediatric Dose for Motion Sickness:
> 12 years: 25 to 50 mg orally once a day as needed. Siguran should be administered one hour prior to travel and continued for the duration of exposure.
Do not exceed 50 mg in 24 hours.
See also:
What is the most important information I should know about Siguran?
You should not take this medication if you are allergic to Siguran.
Before taking Siguran, tell your doctor if you have asthma or other breathing disorder, glaucoma, an enlarged prostate, or problems with urination.
Use Siguran chewable tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Siguran chewable tablets by mouth with or without food.
- Siguran chewable tablets may be chewed or swallowed whole.
- For prevention of motion sickness, take Siguran chewable tablets at least 1 hour before activity or travel.
- Use Siguran chewable tablets exactly as directed on the package, unless instructed differently by your doctor. Follow any warnings and precautions on the label.
- If you miss a dose of Siguran chewable tablets and you are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Siguran chewable tablets.
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.Siguran is an antihistamine that is used to prevent and treat nausea, vomiting, and dizziness caused by motion sickness. It may also be used to reduce dizziness and loss of balance (vertigo) caused by inner ear problems.
How to use Siguran
Follow all directions on the product package. If your doctor has prescribed this medication, take it as directed. If you are uncertain about any of the information, consult your doctor or pharmacist.
Take this medication by mouth with or without food. The chewable tablets should be chewed thoroughly before being swallowed.
The dosage is based on your medical condition and response to treatment. Do not increase your dose or take this medication more often than directed.
To prevent motion sickness, take the first dose one hour before starting activity such as travel.
Tell your doctor if your condition does not improve or if it worsens.
See also:
What other drugs will affect Siguran?
There may be other drugs that can interact with Siguran. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
See also:
What are the possible side effects of Siguran?
Applies to Siguran: oral capsule, oral tablet, oral tablet chewable
In addition to its needed effects, some unwanted effects may be caused by Siguran (the active ingredient contained in Siguran). In the event that any of these side effects do occur, they may require medical attention.
Major Side Effects
You should check with your doctor immediately if any of these side effects occur when taking Siguran:
Incidence not known:
- Cough
- difficulty swallowing
- dizziness
- drowsiness
- fast heartbeat
- hives
- itching
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- shortness of breath
- skin rash
- tightness in the chest
- unusual tiredness or weakness
Minor Side Effects
Some of the side effects that can occur with Siguran may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:
Rare
- Blurred vision
- Dry mouth
- headache