Components:
Medically reviewed by Oliinyk Elizabeth Ivanovna, PharmD. Last updated on 26.06.2023
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Top 20 medicines with the same components:
Each film-coated tablet contains Aceclofenac (Panama Plus) 100 mg, Paracetamol (Panama Plus) 500 mg.
Oral
Pain and inflammation
Adult: Each tablet contains Aceclofenac (Panama Plus) 100 mg and Paracetamol (Panama Plus) 500 mg: 1 tablet in the morning and 1 tablet in the evening. Max: 2 tablets/day.
Oral
Pain and inflammation
Adult: Each tablet contains Aceclofenac (Panama Plus) 100 mg and Paracetamol (Panama Plus) 500 mg: 1 tablet in the morning and 1 tablet in the evening. Max: 2 tablets/day.
Panama Plus is contraindicated in the following situations: Patients sensitive to Aceclofenac (Panama Plus), Paracetamol (Panama Plus) or to any of the excipients of the product. Patients in whom aspirin or other Non-Steroidal Anti-Inflammatory Drug, precipitate attacks of bronchospasm, acute rhinitis or urticaria or patients hypersensitive to drugs. Patients with active or suspected peptic ulcer or gastrointestinal bleeding or bleeding disorders. Patients with severe heart failure, hypertension, hepatic or renal insufficiency. Third trimester of pregnancy.
Paracetamol (Panama Plus): Reduced absorption of cholestyramine within 1 hr of administration.
Accelerated absorption with metoclopramide.
Increased risk of liver damage in chronic alcoholics. Increased risk of toxicity with high doses or long term administration of barbiturates, carbamazepine, hydantoins, isoniazid, rifampicin and sulfinpyrazone.
Aceclofenac (Panama Plus): May increase the plasma concentrations of lithium and digoxin.
Increased nephrotoxicity with diuretics. Serum-potassium should be monitored when used with potassium-sparing diuretics. May enhance activity of anticoagulants. May increase plasma methotrexate levels leading to toxicity if administered within 2-4 hours of methotrexate administration. Risk of convulsions with quinolones. Potentially fatal.
Paracetamol (Panama Plus): Nausea, allergic reactions, skin rashes, acute renal tubular necrosis. Aceclofenac (Panama Plus): Diarrhoea, headache, vertigo, dizzies, nervousness, tinnitus, depression, drowsiness, insomnia; fever, angioedema, bronchospasm, rashes; blood dyscrasias.
Potentially Fatal: Paracetamol (Panama Plus): Very rare, blood dyscrasias (eg, thrombocytopaenia, leucopaenia, neutropaenia, agranulocytosis); liver damage. Aceclofenac (Panama Plus): Severe GI bleeding; nephrotoxicity.