Components:
Medically reviewed by Kovalenko Svetlana Olegovna, PharmD. Last updated on 26.06.2023
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Top 20 medicines with the same components:
Akf-PLUS
Each film-coated tablet contains Aceclofenac (Acf-PLUS) 100 mg, Paracetamol (Acf-PLUS) 500 mg.
An indication is a term used to refer to a list of conditions, symptoms, or diseases for which a medication is prescribed or used by a patient. For example, acetaminophen or paracetamol (Acp-PLUS) is used by the patient for fever, or the doctor prescribes it for headaches or body aches. Now fever, headache, and body aches are indications for the use of Paracetamol (Acp-PLUS). The patient should be aware of the indications of medications used for common conditions, because they can be taken without a prescription at the pharmacy.
Oral
Pain and inflammation
Adult: Each tablet contains Aceclofenac (Acf-PLUS) 100 mg and Paracetamol (Acf-PLUS) 500 mg: 1 tablet in the morning and 1 tablet in the evening. Maximum: 2 tablets per day.
Oral
Pain and inflammation
Adult: Each tablet contains Aceclofenac (Acf-PLUS) 100 mg and Paracetamol (Acf-PLUS) 500 mg: 1 tablet in the morning and 1 tablet in the evening. Maximum: 2 tablets per day.
Akf-PLUS it is contraindicated in the following situations: Patients who are sensitive to Aceclofenac (Acf-PLUS), Paracetamol (Acf-PLUS) or to any of the excipients of the drug. Patients in whom aspirin or other non-steroidal anti-inflammatory drugs cause attacks of bronchospasm, acute rhinitis or urticaria, or patients with hypersensitivity to drugs. Patients with active or suspected peptic ulcer disease, gastrointestinal bleeding, or blood clotting disorders. Patients with severe heart failure, hypertension, hepatic or renal insufficiency. Third trimester of pregnancy.
Paracetamol (Acf-PLUS): Decrease in the absorption of cholestyramine within 1 h after administration.
Increased risk of liver damage in chronic alcoholics. Increased risk of toxicity with high doses or prolonged use of barbiturates, carbamazepine, hydantoin, isoniazid, rifampicin, and sulfinpyrazone.
Aceclofenac (Acf-PLUS): It is possible to increase the concentration of lithium and digoxin in the blood plasma.
Increased nephrotoxicity when using diuretics. When using potassium-sparing diuretics, the level of potassium in the blood serum should be monitored. May increase the activity of anticoagulants. May increase the level of methotrexate in the blood plasma, which leads to toxicity when administered within 2-4 hours after administration of methotrexate. Risk of seizures when taking quinolones. Potentially fatal.
Paracetamol (Acp-PLUS): Nausea, allergic reactions, skin rash, acute renal tubule necrosis. Aceclofenac (Acf-PLUS): Diarrhea, headache, dizziness, nervousness, tinnitus, depression, drowsiness, insomnia, fever, angioedema, bronchospasm, rash, blood dyscrasia.
Potentially Fatal: Paracetamol (Acp-PLUS): Very rare, blood dyscrasia (e.g., thrombocytopenia, leukopenia, neutropenia, agranulocytosis), liver damage. Aceclofenac (Acf-PLUS): Severe gastrointestinal bleeding, nephrotoxicity.