Components:
Medically reviewed by Fedorchenko Olga Valeryevna, PharmD. Last updated on 26.06.2023

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Top 20 medicines with the same components:
Each tablet contains Aceclofenac (Aceclofenac 100MG + Paracetamol (Aceclofenac 100MG + PARACETAMOL 325MG + CHLORZOXAZONE 250MG TABLET) 325MG + Chlorzoxazone (Aceclofenac 100MG + Paracetamol (Aceclofenac 100MG + PARACETAMOL 325MG + CHLORZOXAZONE 250MG TABLET) 325MG + CHLORZOXAZONE 250MG TABLET) 250MG TABLET) 100 mg, Chlorzoxazone (Aceclofenac 100MG + Paracetamol (Aceclofenac 100MG + PARACETAMOL 325MG + CHLORZOXAZONE 250MG TABLET) 325MG + CHLORZOXAZONE 250MG TABLET) 500 mg and acetaminophen 375 mg.
Acute painful inflammatory conditions, which may include skeletal muscle spasm and pain associated with sprains, strains and other traumatic muscle injuries; myalgias; arthritis; low back pain; tension headache; tooth extraction; torticollis; fibrositis; spondylitis; cervical root and disc syndromes; postsurgical pain.
Usual Dose: Twice daily, orally.
Children: There are no clinical data on the use of Aceclofenac (Aceclofenac 100MG + Paracetamol (Aceclofenac 100MG + PARACETAMOL 325MG + CHLORZOXAZONE 250MG TABLET) 325MG + Chlorzoxazone (Aceclofenac 100MG + Paracetamol (Aceclofenac 100MG + PARACETAMOL 325MG + CHLORZOXAZONE 250MG TABLET) 325MG + CHLORZOXAZONE 250MG TABLET) 250MG TABLET) in children.
Renal Insufficiency: There is no evidence that the dosage of Aceclofenac (Aceclofenac 100MG + Paracetamol (Aceclofenac 100MG + PARACETAMOL 325MG + CHLORZOXAZONE 250MG TABLET) 325MG + Chlorzoxazone (Aceclofenac 100MG + Paracetamol (Aceclofenac 100MG + PARACETAMOL 325MG + CHLORZOXAZONE 250MG TABLET) 325MG + CHLORZOXAZONE 250MG TABLET) 250MG TABLET) needs to be modified in patients with mild renal impairment, but as with other NSAID, caution should be exercised.
Hepatic Insufficiency: There is some evidence that the dose of Aceclofenac (Aceclofenac 100MG + Paracetamol (Aceclofenac 100MG + PARACETAMOL 325MG + CHLORZOXAZONE 250MG TABLET) 325MG + Chlorzoxazone (Aceclofenac 100MG + Paracetamol (Aceclofenac 100MG + PARACETAMOL 325MG + CHLORZOXAZONE 250MG TABLET) 325MG + CHLORZOXAZONE 250MG TABLET) 250MG TABLET) should be reduced in patients with hepatic impairment and it is suggested that an initial dose of 100 mg be used.
Hypersensitivity to Aceclofenac (Aceclofenac 100MG + Paracetamol (Aceclofenac 100MG + PARACETAMOL 325MG + CHLORZOXAZONE 250MG TABLET) 325MG + Chlorzoxazone (Aceclofenac 100MG + Paracetamol (Aceclofenac 100MG + PARACETAMOL 325MG + CHLORZOXAZONE 250MG TABLET) 325MG + CHLORZOXAZONE 250MG TABLET) 250MG TABLET), Chlorzoxazone (Aceclofenac 100MG + Paracetamol (Aceclofenac 100MG + PARACETAMOL 325MG + CHLORZOXAZONE 250MG TABLET) 325MG + CHLORZOXAZONE 250MG TABLET), acetaminophen or any of the components; severe heart failure; severely impaired hepatic or renal function; and acute porphyria. Aceclofenac (Aceclofenac 100MG + Paracetamol (Aceclofenac 100MG + PARACETAMOL 325MG + CHLORZOXAZONE 250MG TABLET) 325MG + Chlorzoxazone (Aceclofenac 100MG + Paracetamol (Aceclofenac 100MG + PARACETAMOL 325MG + CHLORZOXAZONE 250MG TABLET) 325MG + CHLORZOXAZONE 250MG TABLET) 250MG TABLET) should not be administered to patients with active peptic ulcer or GI bleeding. Aceclofenac (Aceclofenac 100MG + Paracetamol (Aceclofenac 100MG + PARACETAMOL 325MG + CHLORZOXAZONE 250MG TABLET) 325MG + Chlorzoxazone (Aceclofenac 100MG + Paracetamol (Aceclofenac 100MG + PARACETAMOL 325MG + CHLORZOXAZONE 250MG TABLET) 325MG + CHLORZOXAZONE 250MG TABLET) 250MG TABLET) should not be prescribed during pregnancy, unless there are compelling reasons for doing so. The lowest effective dosage should be used.
Drug interactions associated with Zifam Aceclofenac 100MG + PARACETAMOL 325MG + CHLORZOXAZONE 250MG TABLET are similar to those observed with other NSAIDs. Aceclofenac (Aceclofenac 100MG + Paracetamol (Aceclofenac 100MG + PARACETAMOL 325MG + CHLORZOXAZONE 250MG TABLET) 325MG + Chlorzoxazone (Aceclofenac 100MG + Paracetamol (Aceclofenac 100MG + PARACETAMOL 325MG + CHLORZOXAZONE 250MG TABLET) 325MG + CHLORZOXAZONE 250MG TABLET) 250MG TABLET) increase plasma concentration of lithium, digoxin and methotrexate, increase activity of anticoagulants, inhibit the activity of diuretics, enhance cyclosporin nephrotoxicity and precipitate convulsions when co-administered with quinolones. The co-administration of Aceclofenac (Aceclofenac 100MG + Paracetamol (Aceclofenac 100MG + PARACETAMOL 325MG + CHLORZOXAZONE 250MG TABLET) 325MG + Chlorzoxazone (Aceclofenac 100MG + Paracetamol (Aceclofenac 100MG + PARACETAMOL 325MG + CHLORZOXAZONE 250MG TABLET) 325MG + CHLORZOXAZONE 250MG TABLET) 250MG TABLET) with other NSAIDS or corticosteroids may result in increased frequency of adverse events. Potential hepatotoxicity of acetaminophen may be increased by large doses or long-term administration of barbiturates, carbamazepine, hydantoin, isoniazid, rifampin and sulfopyrazone.
GI effects.