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Medically reviewed by Fedorchenko Olga Valeryevna, PharmD. Last updated on 26.06.2023

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Bepanthen ointment is a derivative of a B complex vitamin called pantothenic acid and the injection is a sterile, nonpyrogenic, aqueous solution. The injection is indicated for use as a gastrointestinal stimulant. Additionally, Bepanthen ointment is available in combination as a hair tonic to improve scalp health and hair growth, as a cream to calm redness and irritation of the skin, and as an anti-aging cream. This drug is not currently FDA approved for the aformentioned indications; however, it is currently approved for use in multivitamin infusion products
Coenzyme A (metabolite of Bepanthen ointment) is important for deep penetrating moisturizer; stimulates epithelization; has wound healing effect; has an anti-inflammatory effect.
Only the D-Panthenol is the provitamin of D-Pantothenic acid (vitamin B5), not the L-Panthenol.
A cream with Bepanthen ointment regularly applied to the skin improves the moisture content of dry skin significantly.
A cream with 5% Bepanthen ointment accelerates the healing of superficial wounds by approximately 30%.
An ointment with Bepanthen ointment prevents erythema due to UV light.
Bepanthen ointment ointment also protects the lips against solar herpes, Sun burns, mild burns, skin irritations, dry or cracked skin, cosmetic or shaving rashes, post chemical peeling treatment, post laser resurfacing treatment ( 11th -15th day).
Bepanthen ointment is effective for preventing / treating nappy dermatitis in infants.
Relieving dry skin, preventing and treating sore nipples during breast-feeding, and promoting healing of burns and poorly-healing wounds. It may also be used for other conditions as determined by your doctor.
Bepanthen ointment cream is an emollient. The exact way Bepanthen ointment cream works is unknown.
Prevention of post-operative adynamic ileus: 250 mg (1 mL) or 500 mg (2 mL) intramuscularly. Repeat in 2 hours and then every 6 hours until all danger of adynamic ileus has passed.
Treatment of adynamic ileus: 500 mg (2 mL) intramuscularly. Repeat in 2 hours and then every 6 hours as needed.
Intravenous administration: Bepanthen ointment Injection 2 mL (500 mg) may be mixed with bulk I.V. solutions such as glucose or Lactated Ringer’s and slowly infused intravenously.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.
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What is the most important information I should know about Bepanthen ointment?
There are no known contraindications to the use of Bepanthen ointment Injection.
Use Bepanthen ointment cream as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Bepanthen ointment cream is for external use only.
- Apply Bepanthen ointment cream directly to the affected areas once or twice daily, or as directed by your health care provider.
- Wash and completely dry the affected area. Gently rub the medicine in until it is evenly distributed. Wash your hands immediately after using Bepanthen ointment cream, unless your hands are part of the treated area.
- If you miss a dose of Bepanthen ointment cream, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Bepanthen ointment cream.
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.This medication is used as a moisturizer to treat or prevent dry, rough, scaly, itchy skin and minor skin irritations (e.g., diaper rash, skin burns from radiation therapy). Emollients are substances that soften and moisturize the skin and decrease itching and flaking. Some products (e.g., zinc oxide, white petrolatum) are used mostly to protect the skin against irritation (e.g., from wetness).
Dry skin is caused by a loss of water in the upper layer of the skin. Emollients/moisturizers work by forming an oily layer on the top of the skin that traps water in the skin. Petrolatum, lanolin, mineral oil and dimethicone are common emollients. Humectants, including glycerin, lecithin, and propylene glycol, draw water into the outer layer of skin. Many products also have ingredients that soften the horny substance (keratin) that holds the top layer of skin cells together (e.g., urea, alpha hydroxy acids such as lactic/citric/glycolic acid, and allantoin). This helps the dead skin cells fall off, helps the skin keep in more water, and leaves the skin feeling smoother and softer.
How to use Bepanthen ointment topical
Use this product as directed. Some products require priming before use. Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.
Some products need to be shaken before use. Check the label to see if you should shake the bottle well before using. Apply to the affected areas of the skin as needed or as directed on the label or by your doctor. How often you apply the medication will depend on the product and your skin condition. To treat dry hands, you may need to use the product every time you wash your hands, applying it throughout the day.
If you are using this product to help treat diaper rash, clean the diaper area well before use and allow the area to dry before applying the product.
If you are using this product to help treat radiation skin burns, check with radiation personnel to see if your brand can be applied before radiation therapy.
Follow all the directions on the label for proper use. Apply to the skin only. Avoid sensitive areas such as your eyes, inside your mouth/nose, and the vaginal/groin area, unless the label or your doctor directs you otherwise. Check the label for directions about any areas or types of skin where you should not apply the product (e.g., on the face, any areas of broken/chapped/cut/irritated/scraped skin, or on a recently shaved area of the skin). Consult your doctor or pharmacist for more details.
Use this medication regularly to get the most benefit from it. Most moisturizers need water to work well. Apply the product after bathing/showering while the skin is still damp. For very dry skin, your doctor may instruct you to soak the area before using the product. Long, hot, or frequent bathing/washing can worsen dry skin.
If your condition persists or worsens, or if you think you may have a serious medical problem, seek immediate medical attention.
If you are using this product under your doctor's direction, your doctor or pharmacist may already be aware of possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.
If your doctor has directed you to use this product, or if you use any prescription product on the skin, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, including other skin care products.
Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
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What are the possible side effects of Bepanthen ointment?
There have been a few reports of allergic reactions and single reports of several other adverse events in association with the administration of Bepanthen ointment. A causal relationship is uncertain. One patient experienced itching, tingling, difficulty in breathing. Another patient had red patches of skin. Two patients had generalized dermatitis and one patient urticaria.
One patient experienced temporary respiratory difficulty following administration of Bepanthen ointment injection 5 minutes after succinylcholine was discontinued.
One patient experienced a noticeable but slight drop in blood pressure after administration of Bepanthen ointment while in the recovery room.
One patient experienced intestinal colic one-half hour after the drug was administered.
Two patients vomited following administration and two patients had diarrhea 10 days post-surgery and after Bepanthen ointment Injection.
One elderly patient became agitated after administration of the drug.