Components:
Method of action:
Medically reviewed by Militian Inessa Mesropovna, PharmD. Last updated on 20.03.2022
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Top 20 medicines with the same components:
treatment of non-inflammatory keratopathy, including corneal dystrophy, recurrent erosions, corneal lesions when wearing contact lenses,
as an auxiliary therapy to stimulate the healing process of the cornea and conjunctiva in their injuries and burns (chemical and thermal),
as an adjunct therapy in the treatment of infectious corneal lesions of bacterial, viral or fungal origin.
Conjunctivally. In the lower conjunctival sac of the affected eye, 1 drop 4 times a day, as well as 1 drop before bedtime.
Individual hypersensitivity to any of the components of the drug.
With caution: pregnancy, breast-feeding period (no clinical data available).
On the part of the visual organ: itching, hyperemia, conjunctival edema, pain, sensation of a foreign body in the eye, increased lacrimation, transient blurred vision.
On the part of the immune system: very rarely — allergic reactions (itching, skin rashes).
There are no data on drug overdose.
The active ingredient of the drug Korneregel is dexpanthenol / panthenol-a precursor of pantothenic acid, which, thus, has all the same biological properties as D-pantothenic acid, which, having turned into coenzyme A in the human body, participates in many metabolic processes. The data obtained in animal experiments indicate an increase in fibroblast proliferation and the presence of a regenerating effect. When used externally, dexpanthenol is able to fill the increased need for damaged skin or mucous membranes in pantothenic acid. The eye gel has a high viscosity, which allows you to achieve long-term contact of dexpanthenol with the surface of the eye mucosa
To increase the duration of contact of an aqueous solution of dexpanthenol with the corneal epithelium, the preparation Korneregel contains a carbomer, which, due to its high molecular weight, does not penetrate into the tissues of the eyeball and is not absorbed into the systemic bloodstream.
- Tissue repair stimulator [Vitamins and vitamin-like agents]
- Tissue Repair Stimulator [Regenerants and Reparants]
- Tissue Repair Stimulator [Ophthalmic Agents]
Cases of incompatibility with other drugs are unknown.
In cases where additional local therapy with eye drops/ointments is performed, the interval between the administration of Korneregel and other ophthalmic drugs should be at least 15 minutes.
Due to its physical properties, the drug Korneregel can prolong the residence time of other ophthalmic drugs in the eye and thereby enhance their effect. Therefore, the Korneregel should be used last.
In a place protected from light, at a temperature not exceeding 25 °C.
Keep out of reach of children.
Shelf life of the drug Korneregel2 года. После вскрытия флакона препарат следует использовать в течение 6 нед.Do not use after the expiration date indicated on the package.
Eye Gel | 1 g |
active substance: | |
dexpanthenol | 50 mg |
excipients: cetrimide-0.1 mg, disodium edetate-0.1 mg, carbomer-0.1 mg, sodium hydroxide-1.01 mg, water for injection-945.79 mg |
Eye gel, 5%. 5 or 10 g each in a tube with a nozzle head and a screw-on cap made of PVP. 1 tube in a cardboard pack.
There are no data on the effects of oral pantothenic acid on the course of pregnancy and fetal development or the health of the newborn. However, it is known that when taken orally, pantothenic acid, into which dexpanthenol is metabolized, freely penetrates the placenta and is excreted through breast milk in proportion to the amount of the drug taken.
Since there are no data on the concentration of dexpanthenol (pantothenic acid) in the blood plasma after topical application in the form of an eye gel, the use of Korneregel during pregnancy and/or breastfeeding is possible only after consulting a doctor, when the expected benefit to the mother exceeds the potential risk to the fetus and/or child.
Without a prescription.
Korneregel should not be used as a monotherapy for infectious corneal lesions of bacterial, viral or fungal origin.
The preservative cetrimide, which is part of the drug, with prolonged or too frequent use can cause local eye irritation, allergic reactions (burning, redness, feeling of a foreign body in the eye) and damage to the corneal epithelium.
During treatment with Korneregel, it is not recommended to wear contact lenses due to possible incompatibility of the drug with the lens material. However, if contact lenses are still indicated, they should be removed before using Korneregel and put on again no earlier than 15 minutes after instillation of the drug.
Do not touch the tip of the pipette tube to the eye.
The tube must be closed after each use.
If there is no improvement in the condition, there are signs of eye irritation, stop using the drug and seek medical advice.
Influence on the ability to drive vehicles and complex mechanisms. After instillation of the drug, a thin film forms on the cornea, which can cause short-term blurred vision, thereby reducing the reaction rate. Therefore, the management of vehicles and mechanisms should begin when the clarity of vision is restored.
S01XA12 Dexpanthenol
- H16 Keratitis
- H16. 0 Corneal ulcer
- H18. 4 Corneal degeneration
- H18. 9 Corneal disease, unspecified
- H19. 2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere
- S05 Eye and socket injury
- T26 Thermal and chemical burns limited to the area of the eye and its appendage
- Z97. 3 Availability of glasses and contact lenses
Transparent or slightly opalescent, colorless to easily flowable gel.