Componentes:
Método de ação:
Opção de tratamento:
Medicamente revisado por Fedorchenko Olga Valeryevna, Farmácia Última atualização em 03.04.2022
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20 principais medicamentos com os mesmos componentes:
20 principais medicamentos com os mesmos tratamentos:
Levomycetin liniment is a broad spectrum bacteriostatic antibiotic. It is active against a wide range of Gram-negative and Gram-positive organisms, including Salmonella typhi, Haemophilus influenzae, Neisseria meningitidis, Streptococcus pneumoniae and Bacteroides fragilis. It has antirickettsial and antichlamydial activity. It is indicated for the topical treatment of superficial ocular infections caused by pathogens which are sensitive to it.
Levomycetin liniment is indicated in adults and children.
Posology
Adults (and the elderly) and children
One or two drops applied to each affected eye up to six times daily or more frequently if required. (Severe infections may require one to two drops every fifteen to twenty minutes initially, reducing the frequency of instillation gradually as the infection is controlled).
Paediatric population
Dosage adjustment may be necessary in newborn infants because of reduced systemic elimination due to immature metabolism and the risk of dose-related adverse effects. The maximum duration of treatment is 10-14 days.
Method of administration
For topical ocular use.
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- Mielossupressão durante exposição prévia ao linimento de levomicetina.
- História pessoal ou familiar conhecida de discrasias sanguíneas, incluindo anemia aplástica
Levomycetin liniment is absorbed systemically from the eye and toxicity has been reported following chronic exposure.
Bone marrow hypoplasia, including aplastic anaemia and death, has been reported following topical use of Levomycetin liniment. Whilst the hazard is a rare one, it should be borne in mind when assessing the benefits expected from the use of the compound.
Where Levomycetin liniment eye drops are used on a long term or intermittent basis, it may be advisable to perform a routine blood profile before therapy and at appropriate intervals thereafter to detect any haemopoietic abnormalities.
In severe infections topical use of Levomycetin liniment should be supplemented with appropriate systemic treatment.
Prolonged use should be avoided as it may increase the likelihood of sensitisation and the emergence of resistant organisms.
If any new infection appears during the treatment, the antibiotic should be discontinued and appropriate measures taken. Levomycetin liniment should be reserved for use only in infections for which it is specifically indicated.
Levomycetin liniment Eye Drops does not provide adequate coverage against Pseudomonas aeruginosa and Serratia marcescens.
Do not use for more than 5 days without consulting a doctor.
Medical advice should be sought if there is no improvement in the condition after 2 days or if symptoms worsen at any time.
Patients should be referred to their doctor if any of the following apply:
- Disturbed vision
- Severe pain within the eye
- Photophobia
- Eye inflammation associated with a rash on the scalp or face
- The eye looks cloudy
- The pupil looks unusual
- Suspected foreign body in the eye
Patients should also be referred to their doctor if any of the following in his/her medical history apply:
- Previous conjunctivitis in the recent past
- Glaucoma
- Dry eye syndrome
- Eye surgery or laser treatment in the last 6 months
- Eye injury
- Current use of other eye drops or eye ointment
- Contact lens use
Soft contact lenses should not be worn during treatment with Levomycetin liniment eye drops due to absorption of the preservative onto the lens which may cause damage to the lens. It is recommended that all types of contact lenses be avoided during ocular infections.
The packaging will convey the following information:
- If symptoms do not improve within 48 hours talk to your doctor
- Seek further immediate medical advice at any time if symptoms worsen
- Do not use if you are allergic to Levomycetin liniment or any of the ingredients
Phenylmercuric nitrate is irritating to the skin. Topical application to eyes has been associated with mercurialentis and atypical band keratopathy.
O uso de colírios pode causar desfoque transitório da visão. Os pacientes não devem dirigir ou operar máquinas perigosas, a menos que a visão seja clara.
Afecções oculares:
Irritação transitória, queimação, picada e reações de sensibilidade, como prurido e dermatite.
Distúrbios do sistema imunológico:
Reações de hipersensibilidade, incluindo angioedema, anafilaxia, urticária, febre, dermatite vesicular e maculopapular.
Doenças do sangue e do sistema linfático :
Depressão da medula óssea e anemia raramente aplástica foram relatadas após o uso tópico de linimento de levomicetina. Embora o risco seja raro, deve-se ter em mente ao avaliar os benefícios esperados com o uso deste composto.
Relato de suspeitas de reações adversas :
A notificação de suspeitas de reações adversas após a autorização do medicamento é importante. Permite a monitorização contínua da relação benefício / risco do medicamento. Solicita-se aos profissionais de saúde que relatem qualquer suspeita de reação adversa via esquema de cartão amarelo em www.mhra.gov.uk/yellowcard.
É improvável que a ingestão acidental de gotas cause toxicidade sistêmica devido ao baixo teor de antibióticos no produto. Se ocorrer irritação, dor, inchaço, lacrimação ou fotofobia após contato visual indesejado, os olhos expostos devem ser irrigados por pelo menos 15 minutos. Se os sintomas persistirem após isso, um exame oftalmológico deve ser considerado.
Grupo farmacoterapêutico: Antibióticos
Código ATC: S01AA01
O linimento da levomicetina é um antibiótico de amplo espectro com atividade bacteriostática e é eficaz contra uma ampla gama de organismos gram-negativos e gram-positivos, incluindo Haemophilus influenzae, Streptococcus pneumoniae, Staphylococcus aureus, Streptococcus viridans, Moraxella species e Enterobacteriaceae, os principais patógenos bacteria responsáveis por agudos. O linimento da levomicetina exerce seu efeito antibacteriano ao ligar reversivelmente aos ribossomos bacterianos, inibindo assim a síntese de proteínas bacterianas.
Evidence suggests that Levomycetin liniment is absorbed systemically via topical ocular administration. Any Levomycetin liniment that is absorbed will be widely distributed in the body tissues and fluids. It is found in cerebrospinal fluid, is secreted in saliva, with the highest concentrations occurring in the kidneys and liver.
Levomycetin liniment also diffuses across the placenta into the foetal circulation and into breast milk.
Levomycetin liniment is excreted chiefly in the urine as the glucuronide with small amounts being excreted via the bile and faeces. It has a reported half life of 1.5 to 5 hours which is increased in patients with liver impairment and neonates to between 24 and 28 hours in the latter.
Não há dados adicionais relevantes para o prescritor.
Nenhum conhecido
No special requirements.
However, we will provide data for each active ingredient