Sudafed PSE

Cold and influenza symptoms; rhinitis; sinusitis

Naproxen (Sudafed PSE) is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Naproxen (Sudafed PSE) works by reducing hormones that cause inflammation and pain in the body.

Pseudoephedrine (Sudafed PSE) is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of Sudafed PSE (Sudafed PSE) is used to treat stuffy nose, sinus congestion, cough, and pain or fever caused by the common cold or flu.

Sudafed PSE (Sudafed PSE) may also be used for purposes other than those listed in this medication guide.

Usual Adult Dose for Nasal Congestion:

Extended-release: Naproxen (Sudafed PSE) 220 mg-Pseudoephedrine (Sudafed PSE) 120 mg orally every 12 hours.

Usual Adult Dose for Analgesic/Antipyretic:

Extended-release: Naproxen (Sudafed PSE) 220 mg-Pseudoephedrine (Sudafed PSE) 120 mg orally every 12 hours.

Usual Pediatric Dose for Nasal Congestion:

12 years or older:

Extended-release: Naproxen (Sudafed PSE) 220 mg-Pseudoephedrine (Sudafed PSE) 120 mg orally every 12 hours.

Usual Pediatric Dose for Analgesic/Antipyretic:

12 years or older:

Extended-release: Naproxen (Sudafed PSE) 220 mg-Pseudoephedrine (Sudafed PSE) 120 mg orally every 12 hours.

See also:
What is the most important information I should know about Sudafed PSE?

Hypersensitivity to aspirin or NSAIDs. Acute GI ulceration or bleeding.

Use Sudafed PSE as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Sudafed PSE by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation. Taking it with food may not lower the risk of stomach or bowel problems (eg, bleeding, ulcers). Talk with your doctor or pharmacist if you have persistent stomach upset.
• Take Sudafed PSE with a full glass of water (8 oz/240 mL) as directed by your doctor.
• Swallow Sudafed PSE whole. Do not break, crush, or chew before swallowing.
• If you take antacids, cholestyramine, or sucralfate, ask your doctor or pharmacist how to take them with Sudafed PSE.
• If you miss a dose of Sudafed PSE and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Sudafed PSE.

See also:
What other drugs will affect Sudafed PSE?

Probenecid, hydantoins, ?-blockers, frusemide, anticoagulants, sulfonylureas, methotrexate.

See also:
What are the possible side effects of Sudafed PSE?

Applies to Naproxen (Sudafed PSE) / Pseudoephedrine (Sudafed PSE): tablets

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; excitability; gas; heartburn; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur while taking Naproxen (Sudafed PSE) / Pseudoephedrine (Sudafed PSE):

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; wheezing); bloody or black, tarry stools; change in the amount of urine produced; chest pain; confusion; dark urine; depression; fainting; fast or irregular heartbeat; fever, chills, or persistent sore throat; hallucinations; loss of appetite; mood or mental changes; numbness of an arm or leg; 1-sided weakness; pale stools; persistent trouble sleeping; red, swollen, blistered, or peeling skin; restlessness; ringing in the ears or hearing changes; seizures; severe dizziness, light-headedness, or headache; severe drowsiness; severe or persistent stomach pain or nausea; severe vomiting; shortness of breath; sudden or unexplained weight gain; swelling of the hands, legs, or feet; tremor; unusual bruising or bleeding; unusual joint or muscle pain; unusual tiredness or weakness; vision or speech changes; vomit that looks like coffee grounds; yellowing of skin or eyes.