Sebitar

Quick links to important sections

Medically reviewed

Rosario Oropesa

Last updated on 22/12/2025

This page provides general, reference-level information compiled from official medical sources. It is not a substitute for professional medical advice, diagnosis, or treatment. For decisions about your health, please consult a qualified healthcare professional.

Overview of Sebitar

Property Description
Active Ingredients Coal Tar, Pine Tar, Salicylic Acid
Form Topical Solution/Scalp Cleanser
Pharmacological Class Keratolytic, Keratoplastic, Antipruritic Combination
Route of Administration Topical, External Use
Origin Derived combination (natural tars and synthetic acid)

What Type of Topical Medicine is Sebitar?

Sebitar is a specialized topical solution, formulated as a scalp cleanser, classified pharmacologically as an Over-The-Counter (OTC) combination keratolytic, keratoplastic, and antipruritic agent. This distinctive product is designed for external use and positioned specifically for the comprehensive management of chronic scalp conditions, such as persistent flaking associated with seborrhoeic dermatitis. It is fundamentally a combination product because it integrates the actions of multiple active agents into a single base, offering a multifaceted approach to care integrated for improving outcomes in complex scalp issues.


Understanding Sebitar's Combination Composition

The medicinal character of Sebitar is derived from its key active ingredients: Coal Tar (as Coal Tar Solution), Pine Tar, and Salicylic Acid. This unique derived combination utilizes established agents from both natural sources (the tars) and the synthetic compound Salicylic Acid. Unlike single-ingredient tar or salicylic acid products, Sebitar's formula combines the effects of the tars—which function as keratoplastic agents to normalize cell production—with the keratolytic action of Salicylic Acid. This combination of tar and salicylic acid is used for improving skin barrier function and reducing scaling. The formulation is intentionally developed as a soap-free aqueous solution, balanced to pH6, a characteristic designed to maintain the natural acidity of the scalp and minimize the potential for further irritation.


General Purpose of Sebitar's Formulation

The general purpose of Sebitar’s formulation is to deliver simultaneous relief and ongoing scalp management by targeting multiple symptoms of chronic irritation and flaking. This synergy leverages the combined properties to influence cell turnover while actively helping to dissolve and lift away existing scales. Together, these actions, complemented by the antipruritic properties of the tars, work to effectively manage symptoms often associated with conditions like scalp psoriasis. The combination of these classes assists in soothing chronic itching and reducing the physical appearance of scales, making it a reliable option for patient self-management.

Regulatory References

  1. Seborrheic dermatitis - Diagnosis and treatment

What side effects are possible with Sebitar?

Possible Side Effects and Safety Information

The official safety profile for topical products containing Coal Tar, Pine Tar, and Salicylic Acid is characterized primarily by local reactions at the site of application and specific exposure-related constraints, as documented in government regulatory monographs and labeling.


Documented Adverse Reactions

The majority of documented effects fall under Skin and Subcutaneous Tissue Disorders. These are often local and transient, especially at the start of use. Adverse reactions explicitly listed in regulatory texts include local irritation, a stinging or burning sensation at the application site, and skin discoloration or staining of the hair. Less common reactions include inflammation of the hair follicles (folliculitis) and contact dermatitis.

Serious adverse reactions, though rare, are documented as events requiring product discontinuation, such as severe skin irritation or signs of hypersensitivity.


Key Safety Constraints and Population Notes

A key safety characteristic is the photosensitizing property of Coal Tar, which increases the skin's tendency to sunburn. Official documents mandate specific caution against excessive sunlight exposure during and for a period following use. Additionally, materials that contact the product (e.g., clothing, bedding) are listed as posing a serious fire hazard.

Population-Specific Constraints: The Salicylic Acid component introduces constraints for specific populations. Use in children under 6 years is not recommended. Furthermore, the product is contraindicated during the third trimester of pregnancy due to the potential for systemic absorption of salicylates.

Overdose and Emergency Response

Overdose and when to seek help

The official overdose profile for this product is determined by the potential for systemic toxicity from its Salicylic Acid component, which can occur through accidental ingestion or extensive topical absorption. This toxicity, known as Salicylism, is classified as potentially severe and life-threatening by regulatory authorities.

Documented Overdose Manifestations

Symptoms documented in regulatory sources include central nervous system effects such as tinnitus (ringing in the ears), headache, and confusion, alongside gastrointestinal disturbances like nausea and vomiting. Physiological signs may include hyperventilation and fever. Severe overdose can lead to profound metabolic acidosis, respiratory failure, and seizures.

When Immediate Medical Help is Required

Regulators mandate that immediate medical attention is required for any suspected overdose or accidental ingestion of the product. Users must contact a Poison Control Center immediately for guidance. Management procedures documented in official sources include symptomatic and supportive treatment, urinary alkalinization, and in severe cases, the procedural requirement for hemodialysis to aid elimination.

Population-Specific Note

A specific regulatory precaution advises against the use of Salicylate-containing products in children and teenagers recovering from viral illnesses due to the documented risk of Reye's syndrome.

Therapeutic Uses of Sebitar

Sebitar is a specialized scalp cleanser formulated for the symptomatic management of chronic skin conditions, and is relevant for easing symptoms that create noticeable physiological strain.

The active ingredients found in Sebitar are used to address symptoms related to physical discomfort in the scalp. The cleanser is commonly used to help manage the symptoms of chronic scalp psoriasis and seborrhoeic dermatitis, and is considered relevant for associated eczema of the scalp. It is applied in contexts marked by the recurrence of pronounced symptoms in conditions like scalp psoriasis, seborrhoeic dermatitis, and chronic flaking. It provides support that helps ease the overall symptom load of these inflammatory conditions.


Management of Persistent Scaling and Itchiness

The cleanser helps address symptom clusters that may become intense or disruptive, such as scaling, dandruff, flaking, chronic itchiness (pruritus), redness, and irritation. It is applicable in conditions that present with visible and disruptive scale manifestations, and may assist with maintaining functional stability by providing supportive relief when symptoms interfere with routine activities. It is relevant in contexts where additional support is needed for symptom management and helps improve day-to-day comfort during symptomatic periods.

“It offers symptomatic relief that helps patients cope more steadily with difficult, recurring episodes.”


Quick Fact: Relief for Chronic Scaling and Itching

Eligibility and Restrictions for Use

Sebitar's eligibility is determined by official regulatory classifications, which define absolute contraindications and mandatory restrictions based on age, physiological status, and underlying conditions.

Populations and Conditions for Non-Eligibility

Scope Item Official Regulatory Status/Classification
Populations for whom use is contraindicated: Individuals with known hypersensitivity to Coal Tar, Pine Tar, Salicylic Acid, or any excipient. Patients with acute porphyrias [Result 2.7].
Condition-specific restrictions: Contraindicated for use on raw, oozing, or extremely irritated skin lesions [Result 2.7]. Patients with kidney or liver diseases require caution [Result 2.2].
Age-related eligibility rules: Use in children under 2 years of age is not recommended unless supervised by a doctor [Result 3.4]. Children 12 years and older are generally eligible [Result 2.7].
Pregnancy and lactation eligibility status: Use is generally not recommended during pregnancy or breastfeeding due to insufficient data, and requires professional consultation [Result 3.7].

Summary of Regulatory Status

The regulatory profile prohibits use based on absolute risks, such as a known allergy to the active ingredients or the presence of specific metabolic disorders. Use is restricted or not recommended for vulnerable groups, including infants and children under two, due to the increased risk of systemic absorption of Salicylic Acid. Conditional use applies to pregnant and lactating patients, and to individuals with impaired renal or hepatic function, reflecting official cautions defined by government authorities.

What should I know about interactions with other medicines?

The interaction profile for Sebitar is defined by restrictions documented in official regulatory labeling for its active components: Coal Tar, Pine Tar, and Salicylic Acid.


A prohibited co-administration exists with certain topical mercury-containing preparations, such as ammoniated mercury ointment, due to the documented risk of a chemical reaction resulting in a black skin stain and severe localized irritation.


Documented Interaction Restrictions

Interaction Type Affected Products / Substances Regulatory Restriction
Pharmacodynamic Additive Effect Other topical peeling agents (e.g., benzoyl peroxide, resorcinol, sulfur, tretinoin) or abrasive cleansers and alcohol-containing preparations. Co-administration is restricted to avoid cumulative local reactions, including excessive dryness, peeling, or irritation.
Environmental Interaction Ultraviolet (UV) radiation (including sunlight and sunlamps). The Coal Tar component is a known photosensitizer; exposure is restricted for up to 24 hours after application to prevent severe phototoxic reactions.
Systemic Exposure Modification Non-topical drugs that affect clearance pathways, such as Probenecid and Ketorolac. Use requires monitoring due to the potential for systemic absorption of Salicylic Acid, which may alter the effects of these agents or increase the risk of systemic side effects.
Timing/Use Separation Other forms of psoriasis therapy or prescription drugs. Use requires timing control or professional supervision to prevent additive adverse effects.

Population-Specific Interaction Note: Regulatory documentation includes a specific caution regarding the use of Salicylic Acid in children and teenagers who are recovering from chickenpox or flu-like symptoms. This interaction is officially associated with an increased risk of Reye’s syndrome due to the potential for systemic exposure of the salicylic acid component in this population.

Mechanism of Action

Sebitar is a topical formulation containing coal tar and salicylic acid, which act on the epithelial tissue of the scalp.

Coal tar is a multifactorial agent. Its primary cellular target is the keratinocyte nucleus, where its polycyclic aromatic hydrocarbons (PAHs) intercalate with DNA. This interaction modifies the transcriptional and translational machinery, acting as a cell growth inhibitor to decrease the rate of keratinocyte hyperproliferation. System-level modulation includes a reduction in epidermal turnover rate and diminished cell-to-cell adhesion in the stratum corneum.

Salicylic acid is a keratolytic agent targeting the intercellular cement between corneocytes in the outer layer of the stratum corneum. It functions by decreasing the pH of this layer, thereby increasing the hydration of the alpha-keratin and solubilizing the intercellular binding material. This interaction promotes the direct shedding of corneocytes, facilitating the removal of excess epithelial buildup.

Dosage and Administration Information

The administration of Sebitar, a topical scalp cleanser containing coal tar and salicylic acid, is a standardized, two-step external application process. These instructions govern the frequency, application steps, and necessary contact time to ensure proper use.


Administration Scope

Property Instruction
Route of administration Topical and External Use Only, applied to the hair and scalp.
Dosing schedule Apply a generous amount to the wet scalp, working it into a rich lather. The product must remain in contact with the scalp for five minutes.
Preparation requirements (if applicable) The hair and scalp must be wet before application. A full rinse and repeat application is required.
Age-group administration rules Do not use on children under 2 years of age unless explicitly directed by a physician.

Instruction Classifications (High-Level)

Property Classification
Administration method type Topical Cleanser (Washed off after brief exposure).
Frequency pattern Twice weekly or up to once daily for symptomatic control.
Application Framework Standardized topical application protocols.
Use-context constraints Confined solely to the scalp; requires a 5-minute retention time.

Resulting Procedural Structure

Step sequence:

  • Wet the hair and scalp with water.
  • Apply the solution and work it into a lather, massaging the scalp.
  • Allow the cleanser to remain on the scalp for five minutes.
  • Rinse the hair and scalp thoroughly.
  • Repeat the entire application and rinse procedure.

Connection to the overall use protocol

The overall use protocol utilizes this specific Topical Cleansing Technique to ensure the necessary contact time with the scalp, which is a key component of the administration method. The protocol outlines the preparation, application duration, and the required repetition, providing a standardized process for the product's use.

Recent Clinical Evidence

Research Evidence / Overview of Studies for Sebitar

Evidence for Use in Scalp Psoriasis

The research examining topical treatments for chronic scalp conditions, such as scalp psoriasis, has often included formulations that combine agents with keratolytic (scale-shedding) and keratoplastic (cell-turnover modulating) properties, similar to the active ingredients in Sebitar. Studies evaluating outcomes related to the use of these combination therapies have mainly used Randomized Controlled Trials (RCTs) and comparative trials focused on adults with chronic plaque psoriasis affecting the scalp. Outcomes related to physical discomfort were monitored using specific tools like the Psoriasis Area and Severity Index (PASI) score and the Physician Global Assessment (PGA) score, which track overall disease activity. Research highlights changes measured during the study period, reporting patterns related to observed changes in scaling and itching assessments among the observed populations.


Evidence for Use in Seborrhoeic Dermatitis

We detail the evidence base, which includes older comparative trials and regulatory recognition criteria that describe the use of these ingredients for the symptomatic manifestations of chronic flaking and irritation associated with seborrhoeic dermatitis. The inclusion of key ingredients like Salicylic Acid and Coal Tar in Over-the-Counter (OTC) Monographs reflects regulatory recognition of their established utility in the context of flaking and scaling symptoms. The research examined populations of adults with symptomatic seborrhoeic dermatitis, monitoring changes in dandruff and flaking severity and the Investigator’s Global Assessment (IGA) score. Findings describe patterns observed in the studies, where the measured outcomes often related to the removal of scales and symptomatic comfort during the initial treatment interval.


What Remains Uncertain in the Research Landscape

While the ingredients in Sebitar have been studied for many years, certainty remains low regarding certain aspects of the evidence. Comparative evidence is lacking in modern trials against some of the newest treatment categories, as much of the core literature is historical. Furthermore, sample sizes were small in some of the older studies, and the evidence quality varies across studies due to differences in design and blinding. The majority of existing clinical trials used in research examining short-term symptom changes only monitor outcomes over relatively modest follow-up durations. The evidence base includes limited data for long-term outcomes and for use in specific subgroups of patients.

Frequently Asked Questions (FAQ)

Common questions about Sebitar (FAQ)

Q: What is the difference between Sebitar and other similar products I see advertised?

A: Sebitar is officially defined by its combination of multiple active agents, including Coal Tar, Pine Tar, and Salicylic Acid. This formulation is designed to target both the process of cell turnover and existing scaling simultaneously, which is different from treatments containing only one active ingredient.

Q: How quickly does Sebitar start working after the first use? / What is the typical time frame before deciding if Sebitar is effective?

A: Official product information emphasizes that best results occur with regular use, which is defined by the official standardized use protocol. Guidance suggests that use should be stopped if the condition worsens or does not show improvement after a period of regular use as directed.

Q: What should I do if I accidentally use too much Sebitar?

A: The product is for external use only on the scalp. If Sebitar is accidentally swallowed, official regulatory guidance instructs that medical help should be sought immediately, or a Poison Control Center should be contacted.

Q: Are there any common foods or drinks that should be avoided while using Sebitar?

A: Official information notes that interactions can occur with certain foods, alcohol, or tobacco when considering medication use in general. Because of this, professional consultation is described as necessary when considering the use of the product in conjunction with these substances.

Q: How does Sebitar's mechanism relate to my skin's natural balance?

A: The formulation is classified as a soap-free product that is balanced to a neutral pH of 6. This characteristic is specifically intended to help maintain the natural acidic balance of the scalp and minimize the potential for further irritation.

Q: Is Sebitar meant for short-term or long-term use?

A: Official drug monographs state that the product is intended for both the relief of current symptoms and to help prevent the chance of their re-occurrence. This reflects its suitability for the ongoing management of chronic scalp conditions.

Q: Can people with sensitive skin generally use Sebitar?

A: Regulatory documents state that use is restricted for skin that is raw, oozing, or extremely irritated. Additionally, common local adverse reactions include a stinging sensation or irritation at the application site.

Q: Does Sebitar interact with common over-the-counter pain relievers?

A: Because the product contains salicylic acid, official caution is documented for children and teenagers recovering from viral infections. This is due to a documented increased risk of Reye’s syndrome linked to systemic exposure to salicylates in that specific population.

Q: What is meant by the 'safety classification' of Sebitar?

A: The safety classification defines the product’s official risk profile, including necessary cautions and constraints. This covers population-specific restrictions and conditions for which use is officially prohibited, known as contraindications.

Q: Are there different strengths or versions of Sebitar available?

A: Official product registries list the medicine as 'Sebitar solution' containing the standard concentration of active ingredients. While the solution is available in various package sizes (e.g., 250 mL, 500 mL), the active strength remains consistent.

Q: Has Sebitar been studied in children or adolescents?

A: Research examining the use of the product's active components is documented primarily in adult populations. Official information indicates there is limited specific data comparing product use in children or adolescents, despite certain age groups being generally eligible.

Q: Why is it important to check the expiration date of Sebitar?

A: The expiration date reflects the officially approved shelf life of the product. This shelf life is supported by stability data, ensuring the medicine maintains its necessary quality and concentration of active ingredients throughout the period of intended use.

Q: What official body approved Sebitar for use in my region?

A: The official approving body for this medicine is the national regulatory authority in the region where it is purchased. Examples of such authorities include the FDA, TGA, or comparable government agencies.

Q: What does the term 'eligibility' mean when applied to using Sebitar?

A: Eligibility defines the official constraints for who can or cannot use the product. It covers absolute prohibitions, known as contraindications, as well as mandatory restrictions based on age, current physiological status, and underlying medical conditions.

How should Sebitar be stored and disposed of?

How to Store and Dispose of Sebitar Solution

Official regulatory documents define specific conditions for storing and handling Sebitar Solution to maintain its stability and safety.

Required Storage Conditions

Constraint Requirement
Temperature Store below 30 C
Environment Keep away from heat, moisture, and direct light
Prohibition Must be kept from freezing
Safety Keep out of the reach of children

Storage must be in a closed container. Due to the presence of alcohol, the product is flammable and must not be used near an open flame.

Disposal

Unused or expired product that is no longer needed must be discarded responsibly. Disposal of the medicine and its container should be done according to local regulations to ensure proper pharmaceutical waste handling.

Attention! Always consult to a doctor or pharmacist before using pills or medicines.

Equivalent of Sebitar found in:

A-Z Index: