Components:
Medically reviewed by Militian Inessa Mesropovna, PharmD. Last updated on 26.06.2023
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Top 20 medicines with the same components:
Relief of bloating, water-wt gain, headache, fever, backache & muscular aches & pains associated w/ pre-menstrual & menstrual pain & discomfort.
2 caplet 4-6 hrly. Max: 8 caplet/day.
Anemia, cardiac, pulmonary, renal & hepatic diseases.
Acetaminophen is metabolized (eliminated by conversion to other chemicals) by the liver. Therefore drugs that increase the action of liver enzymes that metabolize acetaminophen [for example, carbamazepine (Tegretol), isoniazid (INH, Nydrazid, Laniazid), rifampin (Rifamate, Rifadin, Rimactane)] reduce the levels of acetaminophen and may decrease the action of acetaminophen. Doses of acetaminophen greater than the recommended doses are toxic to the liver and may result in severe liver damage. The potential for acetaminophen to harm the liver is increased when it is combined with alcohol or drugs that also harm the liver.
Cholestyramine (Questran) reduces the effect of acetaminophen by decreasing its absorption into the body from the intestine. Therefore, acetaminophen should be administered 3 to 4 hours after cholestyramine or one hour before cholestyramine.
Acetaminophen doses greater than 2275 mg per day may increase the blood thinning effect of warfarin (Coumadin) by an unknown mechanism. Therefore, prolonged administration or large doses of acetaminophen should be avoided during warfarin therapy
Rarely, skin reactions eg urticaria & aggravation of bronchospasm.