Pamprin

Fast & effective relief of period pain.

Acetaminophen (Pamprin) is a pain reliever and fever reducer.

Pamabrom (Pamprin) is a diuretic (water pill).

Pyrilamine (Pamprin) is an antihistamine that reduces the effects of natural chemical histamine in the body.

Acetaminophen (Pamprin), Pamabrom (Pamprin), and Pyrilamine (Pamprin) is a combination medicine used to treat the symptoms of premenstrual syndrome (PMS), such as tension, bloating, water weight gain, headache, muscle pain, cramps, and irritability.

Acetaminophen (Pamprin), Pamabrom (Pamprin), and Pyrilamine (Pamprin) may also be used for purposes not listed in this medication guide.

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What is the most important information I should know about Pamprin?

Anemia, cardiac, pulmonary, renal & hepatic diseases.

Use Acetaminophen (Pamprin)/Pamabrom (Pamprin)/Pyrilamine (Pamprin) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Acetaminophen (Pamprin)/Pamabrom (Pamprin)/Pyrilamine (Pamprin) by mouth with or without food.
• If you miss a dose of Acetaminophen (Pamprin)/Pamabrom (Pamprin)/Pyrilamine (Pamprin) and you are taking it regularly, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Acetaminophen (Pamprin)/Pamabrom (Pamprin)/Pyrilamine (Pamprin).

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What other drugs will affect Pamprin?

Acetaminophen (Pamprin) is metabolized (eliminated by conversion to other chemicals) by the liver. Therefore drugs that increase the action of liver enzymes that metabolize Acetaminophen (Pamprin) [for example, carbamazepine (Tegretol), isoniazid (INH, Nydrazid, Laniazid), rifampin (Rifamate, Rifadin, Rimactane)] reduce the levels of Acetaminophen (Pamprin) and may decrease the action of Acetaminophen (Pamprin). Doses of Acetaminophen (Pamprin) greater than the recommended doses are toxic to the liver and may result in severe liver damage. The potential for Acetaminophen (Pamprin) to harm the liver is increased when it is combined with alcohol or drugs that also harm the liver.

Cholestyramine (Questran) reduces the effect of Acetaminophen (Pamprin) by decreasing its absorption into the body from the intestine. Therefore, Acetaminophen (Pamprin) should be administered 3 to 4 hours after cholestyramine or one hour before cholestyramine.

Acetaminophen (Pamprin) doses greater than 2275 mg per day may increase the blood thinning effect of warfarin (Coumadin) by an unknown mechanism. Therefore, prolonged administration or large doses of Acetaminophen (Pamprin) should be avoided during warfarin therapy

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What are the possible side effects of Pamprin?

Rarely, skin reactions eg urticaria & aggravation of bronchospasm.