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Medically reviewed by Fedorchenko Olga Valeryevna, PharmD. Last updated on 30.04.2022
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indicated in the forms of: cervico-vaginitis and vulvo-vaginitis caused by Trichomonas vaginalis, even if it is associated with Candida albicans, Gardnerella vaginalis or other sensitive bacteria. It should emphasize that trichomoniasis is one of the pathologies most frequently transmitted sexually. meet frequently mixed infections: Trichomonas vaginalis + germs, Trichomonas vaginalis + Candida, Candida + germs. Bacterial vaginosis is now established as one of the predominant causes of infectious vaginitis, the incidence of this condition is evaluated around 30%, with variations depending on different populations. Such diseases of female genitalia are frequently astimptomatice or reduced or ignored symptoms and may predispose mind, if not treated properly and radical, and metaplasia in chronic cervico-vaginal epithelium. It is also quite frequent, especially after anti-infection treatment, incidence of breakthrough fungal variable depending on the type of medicine used.
Restoration Therapy, Vaginal Discharge of Unknown Origin, Mild to Intermediate Vaginal Infections: 1-2 vaginal tablets daily for 6-12 days.
The vaginal tablets should be inserted deeply into the vagina in the evenings before bedtime. This is best performed in a reclining position with the legs slightly bent.
Treatment should be interrupted during menstruation and resumed afterwards.
Atrophic Vaginitis: 1 vaginal tablet daily is recommended for 6-12 days, followed by a maintenance dose of 1 vaginal tablet at 1-2 days/week.
Hypersensitivity to Lactobacillus acidophilus and estriol or to any of the excipients of Meclon 1000.
Malignant changes (estrogen-dependent tumours) in the breast, uterus or vagina; endometriosis (suspected or manifested); vaginal haemorrhaging of unknown origin.
Young girls who have not reached sexual maturity.
Lactobacillus acidophilus is sensitive to various anti-infective agents (local or systemic). Simultaneous treatment of such agents may lead to a reduction in the efficacy of Meclon 1000.
Patients should be advised to inform the physician or pharmacist if they are taking or have recently taken any other medications including those not prescribed.
Incompatibilities: Not applicable.
General Disorders and Administration Site Conditions: A mild stinging or burning (1.6%) may be experienced shortly after the administration of Meclon 1000. In rare cases, intolerability reactions eg, redness and itching have been reported. In one case, hypersensitivity to the lactobacillus lyophilisate contained in Meclon 1000 was observed.
If Meclon 1000 is accidentally administered orally, no adverse effects are to be expected.
Each vaginal tablet contains viable Lactobacillus acidophilus 100 million and estriol 0.03 mg.
Meclon 1000 also contains the following excipients: Lactose, anhydrous disodium phosphate, microcrystalline cellulose, sodium starch glycolate and magnesium stearate.