Components:
Medically reviewed by Fedorchenko Olga Valeryevna, PharmD. Last updated on 26.06.2023

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Top 20 medicines with the same components:
Oral
Motion sickness
Adult: 25-50 mg 1 hr before travelling and repeat 24 hrly if needed.
Child:
Oral
Vertigo and vestibular disorders
Adult: 25-100 mg daily in divided doses. Discontinue if there is no response after 1-2 wk of treatment.
Child:
How should I use Meclizine Hydrochloride Epic?

Use Meclizine Hydrochloride Epic as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Meclizine Hydrochloride Epic by mouth with or without food.
- For prevention of motion sickness, take Meclizine Hydrochloride Epic at least 1 hour before activity or travel.
- Use Meclizine Hydrochloride Epic exactly as directed on the package, unless instructed differently by your doctor. If you are taking Meclizine Hydrochloride Epic without a prescription, follow any warnings and precautions on the label.
- If you miss a dose of Meclizine Hydrochloride Epic and are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Meclizine Hydrochloride Epic.
Meclizine Hydrochloride Epic description
A histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during pregnancy and radiation sickness.
Meclizine Hydrochloride Epic dosage
Vertigo
For the control of vertigo associated with diseases affecting the vestibular system, the recommended dose is 25 to 100 mg daily, in divided dosage, depending upon clinical response.
Motion Sickness
The initial dose of 25 to 50 mg of Meclizine Hydrochloride Epic should be taken one hour prior to embarkation for protection against motion sickness. Thereafter, the dose may be repeated every 24 hours for the duration of the journey.
How supplied
Meclizine Hydrochloride Epic®: 12.5 mg tablets: Bottles of 100 (NDC 0049-2100-66)
Meclizine Hydrochloride Epic®/25: 25 mg tablets: Bottles of 100 (NDC 0049-2110-66)
Meclizine Hydrochloride Epic®/50: 50 mg tablets: Bottles of 100 (NDC 0049-2140-66)
Distributed by: Roerig Division of Pfizer Inc, NY, NY 10017. October 2012
Meclizine Hydrochloride Epic interactions
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What other drugs will affect Meclizine Hydrochloride Epic?
The following drug interactions and/or related problems have been selected on the basis of their potential clinical significance (possible mechanism in parentheses where appropriate)—not necessarily inclusive (» = major clinical significance):
Note: Combinations containing any of the following medications, depending on the amount present, may also interact with this medication.
Alcohol or
CNS depression–producing medications, other (concurrent use may potentiate the CNS depressant effects of either these medications or buclizine)
Anticholinergics or other medications with anticholinergic activity (concurrent use with buclizine may potentiate anticholinergic effects)
Apomorphine (prior administration of buclizine may decrease the emetic response to apomorphine)
Meclizine Hydrochloride Epic side effects
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What are the possible side effects of Meclizine Hydrochloride Epic?
Applies to meclizine: oral capsule, oral tablet, oral tablet chewable
In addition to its needed effects, some unwanted effects may be caused by meclizine (the active ingredient contained in Meclizine Hydrochloride Epic). In the event that any of these side effects do occur, they may require medical attention.
Major Side Effects
You should check with your doctor immediately if any of these side effects occur when taking meclizine:
Incidence not known:
- Cough
- difficulty swallowing
- dizziness
- drowsiness
- fast heartbeat
- hives
- itching
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- shortness of breath
- skin rash
- tightness in the chest
- unusual tiredness or weakness
Minor Side Effects
Some of the side effects that can occur with meclizine may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:
Rare
- Blurred vision
- Dry mouth
- headache
Meclizine Hydrochloride Epic (meclizine) is an antihistamine that reduces the effects of natural chemical histamine in the body.
Meclizine Hydrochloride Epic is used to treat or prevent nausea, vomiting, and dizziness caused by motion sickness. It is also used to treat symptoms of vertigo (dizziness or spinning sensation) caused by disease that affects your inner ear.
Meclizine Hydrochloride Epic may also be used for purposes not listed in this medication guide.
See also:
What is the most important information I should know about Meclizine Hydrochloride Epic?
Meclizine Hydrochloride Epic hydrochloride is contraindicated in individuals who have shown a previous hypersensitivity to it.