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Components:
Docusate
Method of action:
Laxative
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Medically reviewed by Fedorchenko Olga Valeryevna, Pharmacy-Provisor. Last updated on 2019.12.06

Name of the medicinal product

Klyx

Qualitative and quantitative composition

Docusate

Therapeutic indications

The information provided in Therapeutic indications of Klyx is based on data of another medicine with exactly the same composition as the Klyx of the medicine (Docusate). Be careful and be sure to specify the information on the section Therapeutic indications in the instructions to the drug Klyx directly from the package or from the pharmacist at the pharmacy.
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a) To prevent and treat chronic constipation.

(i) to soften hard, dry stools in order to ease defaecation and reduce straining at stool; and

(ii) in the presence of haemorrhoids and anal fissure, to prevent hard, dry stools and reduce straining.

b) As an adjunct in abdominal radiological procedures.

Dosage (Posology) and method of administration

The information provided in Dosage (Posology) and method of administration of Klyx is based on data of another medicine with exactly the same composition as the Klyx of the medicine (Docusate). Be careful and be sure to specify the information on the section Dosage (Posology) and method of administration in the instructions to the drug Klyx directly from the package or from the pharmacist at the pharmacy.
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Route of administration: Oral

Adults and elderly:

Up to 500 mg should be taken daily in divided doses. Treatment should be commenced with large doses, which should be decreased as the condition of the patient improves.

For use with barium meals:

400 mg to be taken with the meal.

Children under 12 years:

Not recommended.

Contraindications

The information provided in Contraindications of Klyx is based on data of another medicine with exactly the same composition as the Klyx of the medicine (Docusate). Be careful and be sure to specify the information on the section Contraindications in the instructions to the drug Klyx directly from the package or from the pharmacist at the pharmacy.
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These capsules should not be administered when abdominal pain, nausea, vomiting or intestinal obstruction is present.

This product should not be given to patients with a known hypersensitivity to Klyx capsules or any of the components.

Patients with rare hereditary problems of fructose intolerance should not take this medicine.

Special warnings and precautions for use

The information provided in Special warnings and precautions for use of Klyx is based on data of another medicine with exactly the same composition as the Klyx of the medicine (Docusate). Be careful and be sure to specify the information on the section Special warnings and precautions for use in the instructions to the drug Klyx directly from the package or from the pharmacist at the pharmacy.
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Organic disorders should be excluded prior to the administration of any laxative.

The treatment of constipation with any medicinal product is only adjuvant to a healthy lifestyle and diet, for example:

- Increased intake of fluids and dietary fibre.

- Advice on appropriate physical activity

If laxatives are needed every day, or if there is persistent abdominal pain, consult your doctor.

Contains sorbitol: do not use this medicine if you are intolerant to small quantities of sugar (sorbitol, fructose).

Contains colouring E110 which may cause allergic reactions.

Effects on ability to drive and use machines

The information provided in Effects on ability to drive and use machines of Klyx is based on data of another medicine with exactly the same composition as the Klyx of the medicine (Docusate). Be careful and be sure to specify the information on the section Effects on ability to drive and use machines in the instructions to the drug Klyx directly from the package or from the pharmacist at the pharmacy.
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None known

Undesirable effects

The information provided in Undesirable effects of Klyx is based on data of another medicine with exactly the same composition as the Klyx of the medicine (Docusate). Be careful and be sure to specify the information on the section Undesirable effects in the instructions to the drug Klyx directly from the package or from the pharmacist at the pharmacy.
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Rarely, these capsules can cause diarrhoea, nausea, abdominal cramps or skin rash.

Reporting of suspected adverse reactions

Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system listed below.

The Yellow Card Scheme

Website: www.mhra.gov.uk/yellowcard

By reporting side effects, you can help provide more information on the safety of this medicine.

Overdose

The information provided in Overdose of Klyx is based on data of another medicine with exactly the same composition as the Klyx of the medicine (Docusate). Be careful and be sure to specify the information on the section Overdose in the instructions to the drug Klyx directly from the package or from the pharmacist at the pharmacy.
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In rare cases of overdose, excessive loss of water and electrolytes should be treated by encouraging the patient to drink plenty of fluid. Electrolyte loss should be replenished where appropriate.

Pharmacodynamic properties

The information provided in Pharmacodynamic properties of Klyx is based on data of another medicine with exactly the same composition as the Klyx of the medicine (Docusate). Be careful and be sure to specify the information on the section Pharmacodynamic properties in the instructions to the drug Klyx directly from the package or from the pharmacist at the pharmacy.
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ATC code: A06A02 Laxatives, softeners, emollients

Docusate sodium is an anionic wetting agent, which acts as a faecal softener by lowering the surface tension and allowing penetration of accumulated hard dry faeces by water and salts.

Docusate Sodium also possesses stimulant activity.

Pharmacokinetic properties

The information provided in Pharmacokinetic properties of Klyx is based on data of another medicine with exactly the same composition as the Klyx of the medicine (Docusate). Be careful and be sure to specify the information on the section Pharmacokinetic properties in the instructions to the drug Klyx directly from the package or from the pharmacist at the pharmacy.
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Docusate sodium exerts its clinical effect in the gastrointestinal tract. There is some evidence that docusate sodium is absorbed and is excreted in the bile. There is also evidence that docusate sodium is capable of enhancing absorption of certain compounds administered concomitantly.

Preclinical safety data

The information provided in Preclinical safety data of Klyx is based on data of another medicine with exactly the same composition as the Klyx of the medicine (Docusate). Be careful and be sure to specify the information on the section Preclinical safety data in the instructions to the drug Klyx directly from the package or from the pharmacist at the pharmacy.
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None stated

Incompatibilities

The information provided in Incompatibilities of Klyx is based on data of another medicine with exactly the same composition as the Klyx of the medicine (Docusate). Be careful and be sure to specify the information on the section Incompatibilities in the instructions to the drug Klyx directly from the package or from the pharmacist at the pharmacy.
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None

Special precautions for disposal and other handling

The information provided in Special precautions for disposal and other handling of Klyx is based on data of another medicine with exactly the same composition as the Klyx of the medicine (Docusate). Be careful and be sure to specify the information on the section Special precautions for disposal and other handling in the instructions to the drug Klyx directly from the package or from the pharmacist at the pharmacy.
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None

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