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Medically reviewed by Oliinyk Elizabeth Ivanovna, PharmD. Last updated on 26.06.2023

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this medicine is indicated for symptomatic control of all allergic conditions responsive to antihistamines, including hay fever, vasomotor rhinitis, urticaria, angioneurotic oedema, food allergy, drug and serum reactions, insect bites.
Also indicated for the symptomatic relief of itch associated with chickenpox in addition to that it ca treat the allergic cough.
Relieving symptoms such as pain and sinus congestion due to colds, upper respiratory infections, and allergies. It may also used for other conditions as determined by your doctor.
Histiacil T is an analgesic and decongestant combination. The analgesic works in the brain to help decrease pain. The decongestant works by constricting blood vessels and reducing swelling in the nasal passages, which decreases stuffiness.
Adult & childn >12 yr 1-2 caplets 4-6 hrly. Max: 8 caplets/day.
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What is the most important information I should know about Histiacil T?
this medicine is contraindicated in individuals with known hypersensitivity to Paracetamol (Histiacil T) or any other constituents of the product.
this medicine is contraindicated in patients with severe hypertension or coronary artery disease.
this medicine is contraindicated in patients who are taking or have taken monoamine oxidase inhibitors within the preceding two weeks. The concomitant use of Pseudoephedrine (Histiacil T) and this type of product may occasionally cause a rise in blood pressure.
Not to be used in children under the age of 12 years.
Use Histiacil T as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Histiacil T may be taken with or without food.
- If you miss a dose of Histiacil T, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Histiacil T.
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What other drugs will affect Histiacil T?
Due to Paracetamol (Histiacil T).
Para Clinical trials: taking the dose of Paracetamol (Histiacil T) uric acid in the blood using the method fosfowolframaat and glycemiebepaling with the glucose oxidase-peroxidase distort.
Oral anticoagulants: the weak link between Paracetamol (Histiacil T) and protein makes its possible association with anti-coagulants. The intake of more than 2 g Paracetamol (Histiacil T) per day over a long period, however the risk of bleeding and requires regular monitoring of the International Normalized Ratio (INR).
Diflunisal: the simultaneous use of diflunisal and Paracetamol (Histiacil T) may increase of 50% cause of the Nazi plasma concentrations of Paracetamol (Histiacil T). Since this involves an increased risk of hepatotoxicity, caution is advised.
Due to pseudo-ephedrine.
MAO inhibitors: drugs with sympathomimetic effects, such as pseudo-ephedrine, causing a release of norepinephrine. By concomitant use of drugs with an MAOI effect increases the amount of nor-epinephrine are present near the nerve receptors by inhibiting the breakdown of catecholamines. The result is a clear increase of the sympathomimetic effect, with a risk of severe hypertension with fever, headache and tachycardia.
Tricyclic antidepressants: risk of hypertension, tachycardia and cardiac arrhythmias.
Guanethidine or related products: elimination of the antihypertensive effect of guanethidine by displacement of the binding sites on neurons. Medicines to avoid an indirect sympathomimetic or other antihypertensives.
Halogenated inhalation anesthetics: a risk for perioperative hypertension uppercut. With a planned surgery is appropriate treatment several days before surgery to stop.
Aluminum: the absorption of Pseudoephedrine (Histiacil T) can be increased with concomitant administration of a gel based on aluminum.
Metmorfine: risk of hyperglycaemia. The glucose must be monitored regularly in case of association with pseudo-ephedrine.
Trazodone: after taking 2 doses of Pseudoephedrine (Histiacil T), confusion, anxiety, panic, depersonalization seen in one patient treated with 250 mg / day trazodone.
Dihydro-ergotamine, linezolid, methyldopa: risk for hypertension.
Sodium: risk reduction in renal excretion of Pseudoephedrine (Histiacil T), depending on urinary pH.
In case of overdose, to alcohol, barbiturates, phenytoin, carbamazepine isoniazid and increase the risk of liver damage.
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What are the possible side effects of Histiacil T?
Applies to acetaminophen / Pseudoephedrine (Histiacil T): capsules, tablets
Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.
Seek medical attention right away if any of these SEVERE side effects occur while taking acetaminophen / Pseudoephedrine (Histiacil T):
Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; mood or mental changes; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; stomach pain; tremor; vision changes; yellowing of skin or eyes.