Cortafriol Complex

this medicine is indicated for symptomatic control of all allergic conditions responsive to antihistamines, including hay fever, vasomotor rhinitis, urticaria, angioneurotic oedema, food allergy, drug and serum reactions, insect bites.

Also indicated for the symptomatic relief of itch associated with chickenpox in addition to that it ca treat the allergic cough.

Adult & childn >12 yr 2 tab every 6 hr. Max 8 tab/day.

this medicine is contraindicated in individuals with known hypersensitivity to Paracetamol (Cortafriol Complex) or any other constituents of the product.

this medicine is contraindicated in patients with severe hypertension or coronary artery disease.

this medicine is contraindicated in patients who are taking or have taken monoamine oxidase inhibitors within the preceding two weeks. The concomitant use of Pseudoephedrine (Cortafriol Complex) and this type of product may occasionally cause a rise in blood pressure.

Not to be used in children under the age of 12 years.

Concomitant use of this medicine with tricyclic antidepressants, sympathomimetic agents (such as decongestants, appetite suppressants and amfetamine-like psychostimulants) or with monoamine oxidase inhibitors, which interfere with the catabolism of sympathomimetic amines, may occasionally cause a rise in blood pressure.

Because of the Pseudoephedrine (Cortafriol Complex) content, this medicine may partially reverse the hypotensive action of drugs which interfere with sympathetic activity including bretylium, betanidine, guanethidine, debrisoquine, methyldopa, alpha- and beta-adrenergic blocking agents.

The use of drugs which induce hepatic microsomal enzymes, such as anticonvulsants and oral contraceptive steroids, may increase the extent of metabolism of Paracetamol (Cortafriol Complex), resulting in reduced plasma concentrations of the drug and a faster elimination rate.

The speed of absorption of Paracetamol (Cortafriol Complex) may be increased by metoclopramide or domperidone and absorption reduced by colestyramine.

The anticoagulant effect of warfarin and other coumarins may be enhanced by prolonged regular use of Paracetamol (Cortafriol Complex) with increased risk of bleeding; occasional doses have no significant effect.

Pseudoephedrine (Cortafriol Complex)

Serious side effects associated with the use of Pseudoephedrine (Cortafriol Complex) are extremely rare. Symptoms of central nervous system excitation may occur, including sleep disturbance and, rarely, hallucinations.

Skin rashes, with or without irritation, have occasionally been reported with Pseudoephedrine (Cortafriol Complex).

Urinary retention has been reported occasionally in men receiving Pseudoephedrine (Cortafriol Complex): prostatic enlargement could have been an important predisposing factor.

Paracetamol (Cortafriol Complex)

Adverse effects of Paracetamol (Cortafriol Complex) are rare but hypersensitivity including skin rash may occur. There have been reports of blood dyscrasias including thrombocytopenia and agranulocytosis, but these were not necessarily causality related to Paracetamol (Cortafriol Complex).