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Doublebase Emollient

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Doublebase Emollient

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Medically reviewed

Laura Arias

Last updated on 22/12/2025

This page provides general, reference-level information compiled from official medical sources. It is not a substitute for professional medical advice, diagnosis, or treatment. For decisions about your health, please consult a qualified healthcare professional.

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Overview of Doublebase Emollient

What is Doublebase Emollient? Foundational Overview

Quick Facts

Property Description
Active Ingredients Liquid Paraffin, Isopropyl Myristate
Form Emollient Gel
Pharmacological Class Emollient Agents (Dermatologicals)
Common Use Maintaining hydration in dry skin conditions
Origin Synthetic/Derived

Defining Doublebase Emollient: Type, Form, and Classification

Doublebase Emollient is a type of topical emollient gel classified under dermatological agents that is used as a supportive measure for various dry skin conditions. It is a leave-on preparation formulated to be applied directly to the skin's surface. This preparation, manufactured by Dermal Laboratories, is an emollient, meaning its primary role is to soothe, hydrate, and soften the skin by forming a protective barrier, a function well-documented in dermatological practice. Unlike traditional, often greasy ointments or thin lotions, the specific gel formulation of Doublebase is a key differentiating factor, offering a texture that is non-greasy and less visible after application, which is clinically recognized for improving patient compliance. The product is intended for cutaneous application, making it a foundational element in daily skin care for affected individuals, from babies to the elderly.


What Is Doublebase Emollient Made Of? Composition and Origin

The preparation is a combination product driven by two principal active ingredients: Liquid Paraffin and Isopropyl Myristate. Liquid Paraffin acts primarily as the occlusive agent, while Isopropyl Myristate, an oil-soluble ester, contributes to the formulation’s smooth texture. Furthermore, the formulation incorporates Glycerol, a crucial humectant that draws water into the outer layer of the skin to enhance hydration. This blend provides a higher oil content than many standard creams while avoiding the heaviness of an ointment. The components are synthetic/derived materials, which undergo significant purification to ensure their stability and compatibility with sensitive skin, providing a robust, high-oil-content gel base, a formulation approach typical for combination emollients.


Doublebase Emollient: Its General Purpose and Function

The general purpose of this emollient is to provide immediate, sustained relief from the primary physical symptoms of skin dryness, such as roughness, scaling, and tightness. It achieves this by creating a robust moisture-sealing film on the skin's surface, which significantly reduces the rate of water loss and evaporation. The advanced formulation is supported by pharmacological studies demonstrating its capacity to maintain skin barrier integrity for extended periods. This action helps to restore the skin’s natural protective function, resulting in a noticeably softer and more flexible texture, thus helping the patient manage and prevent the discomfort associated with dry skin.

Regulatory References

  1. MedlinePlus on Emollients
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What side effects are possible with Doublebase Emollient?

Possible Side Effects and Safety Information

The safety profile of Doublebase Emollient is primarily characterized by a low incidence of documented adverse reactions, which are limited to the application site.


Official Adverse Reaction Scope

Adverse reactions associated with this topical preparation are classified in regulatory documents as occurring in rare cases, affecting less than 1 in 1,000 users. These effects are classified under Skin and Subcutaneous Tissue Disorders and may present as local skin reactions, such as irritation or mild rashes. Official safety labeling notes that these rare localized reactions tend to occur during or soon after the first few uses.

Classification Type of Reaction
Frequency Rare cases
System Affected Skin and Subcutaneous Tissue
Manifestation Local skin reactions (e.g., irritation, mild rashes)

Contraindications and Major Safety Warnings

Contraindication: The emollient should not be used in individuals with a known sensitivity or hypersensitivity to any of its active ingredients, which include Liquid Paraffin and Isopropyl Myristate, or to any of its excipients, as defined in official regulatory documents.

Major Safety Warning: A crucial, non-clinical safety warning documented in regulatory labeling pertains to a serious fire hazard. Fabric (such as clothing, bedding, or dressings) that has been in contact with the emollient can ignite more easily and burn severely. Official guidance specifies that users should not smoke or go near naked flames when using this product.


Population-Specific Safety Notes

The product is officially stated as suitable for use by all age groups, including infants, children, adults, and the elderly. Furthermore, regulatory documents state that Doublebase Emollient can be used during pregnancy and lactation, aligning with the historical widespread use of its components.

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Overdose and Emergency Response

Overdose and when to seek help: Official Regulatory Information

The official regulatory documents establish that an overdose syndrome resulting from the typical topical application of Doublebase Emollient Gel is formally designated as not applicable in the Summary of Product Characteristics. This indicates an absence of a recognized systemic toxicity profile or formally documented severe outcomes following routine or excessive external use.

Documented Overdose Scenario

The only specific exposure scenario documented in regulatory information relates to accidental oral ingestion of the product. Due to the presence of oily ingredients, such as Liquid Paraffin and Isopropyl Myristate, accidental swallowing may lead to the manifestation of diarrhoea. This is the sole clinical effect formally linked to an overdose event in the official prescribing information; no severe or life-threatening systemic outcomes are officially documented.

Emergency Actions and Help-Seeking

In the event of accidental oral ingestion, the management required is primarily symptomatic treatment for the resulting diarrhoea. Regulatory guidance explicitly states that patients must be instructed not to attempt to induce vomiting under any circumstances. While the documented manifestation is generally considered low-severity, medical advice should be sought if the symptoms are persistent, concerning, or if the mandated symptomatic measures are insufficient. No requirements for hospital monitoring or specialized observation are specified in the official overdose section.

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Therapeutic Uses of Doublebase Emollient

What Doublebase Emollient Treats: Main Uses and Benefits

The primary role of Doublebase Emollient is to provide symptomatic relief and foundational skin support across a range of dry skin disorders. It addresses symptom clusters related to inflammatory or irritative states, contributing to improved comfort during periods of heightened symptoms. These preparations are often used to help manage common skin conditions.


Key Therapeutic Applications

This emollient is commonly used as a cornerstone of symptomatic management for conditions characterized by periods of heightened symptoms, such as Atopic Eczema, general Dermatitis, Psoriasis, and age-related issues like Elderly Pruritus. It is applied across domains where additional symptomatic support is needed, offering supportive relief that generally helps ease the overall symptom burden and may assist with maintaining functional stability during flares.

The therapy is relevant for easing symptomatic discomfort, specifically uncomfortable skin tightness, excessive scaling or flaking, and related pruritus (itching). “It plays a role in managing symptoms that interfere with daily comfort.” This support is generally relevant for various patient groups, including babies, children, and older adults.

Quick Fact: Relevant for Easing Dryness, Itching, and Scaling


Supportive Clinical Contexts

Doublebase Emollient is applied in addressing symptoms related to inflammatory or irritative states, providing symptomatic relief that may assist with maintaining functional stability during difficult episodes. It contributes to improved comfort during periods of heightened symptoms by addressing the physical manifestations of dry skin.

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Eligibility and Restrictions for Use

Doublebase Emollient is a topical medicine with a broad population eligibility profile, as defined by government regulatory documents. The criteria for who can and cannot use the medicine are primarily structured around hypersensitivity and age.


Official Contraindications

The single absolute exclusion criterion defined in the regulatory labeling is known hypersensitivity (allergy) to any of the product's components. This includes the active ingredients, Liquid Paraffin and Isopropyl Myristate, or any of the excipients. Individuals with a documented sensitivity to any ingredient must not use the medicine.


Population Eligibility Status

Population Group Eligibility Status
Age Groups Permitted for all ages, including adults, the elderly, children, and infants from birth.
Pregnancy and Lactation Permitted for use during pregnancy and by breastfeeding mothers.
Organ Function No formal restrictions are documented based on specific organ impairment, such as hepatic or renal conditions.

The eligibility scope is wide, reflecting the medicine's topical administration and minimal systemic absorption. The official documentation permits its use across the entire life span.

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What should I know about interactions with other medicines?

Interactions with other medicines and products

Official regulatory information for Doublebase Emollient indicates a minimal risk for clinically significant drug-drug interactions. As a topical emollient, this product is designed for local application to the skin and exhibits negligible systemic absorption, which is the primary reason for the low interaction potential.

Interaction Profile Summary

Official regulatory documents from agencies such as the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA) do not typically list specific, clinically established interactions for this product in the same way they do for systemic medications.

Interaction Scope Regulatory Status
Interacting Medicines/Classes None explicitly listed as contraindications or requiring specific dose adjustments in the interaction sections.
Mechanistic Basis No known interactions based on common mechanisms like enzyme induction/inhibition (e.g., CYP450) or transporter effects are documented.
Timing Requirements No specific time spacing requirements (e.g., separating administration by hours) between this emollient and other medicinal products are mandated in official labeling.

Official Regulatory Statements

The regulatory conclusion is generally that this emollient is not expected to interfere with the action of other medicinal products, including systemic drugs taken by mouth or injection. No formal interaction studies are typically detailed because the minimal absorption makes meaningful pharmacokinetic or pharmacodynamic interactions highly unlikely. Therefore, the official interaction profile is defined by the absence of documented, clinically relevant restrictions on co-administration with other medicines.

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Mechanism of Action

How Doublebase Emollient Works

Doublebase Emollient exerts its action through a precise biophysical mechanism focused entirely on restructuring and stabilizing the skin's outermost layer, the stratum corneum (SC). This effect is achieved through the coordinated actions of occlusion and humectancy, which together normalize the skin's core function of barrier integrity.


️ Occlusion and Water Loss Regulation

The primary mechanism involves the physical interaction of Liquid Paraffin and Isopropyl Myristate with the SC surface. This forms a continuous, non-pharmacological film that directly targets the Trans-Epidermal Water Loss (TEWL) pathway, inhibiting evaporation. This physical occlusion leads to the physiological outcome of sustained water retention within the stratum corneum, allowing the barrier structure to normalize its structural integrity.


Humectancy and Mechanistic Synergy

The secondary domain focuses on the hydrodynamic activity provided by Glycerol. Operating as a potent humectant, it engages the SC Hydrodynamics by attracting and binding water molecules from the underlying dermis and the environment. This coordinated biophysical action is necessary for preserving the mechanical properties of the stratum corneum, which supports a normalized epidermal hydro-state and facilitates healthy corneodesmolysis.

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Dosage and Administration Information

How to Use Doublebase Emollient: Official Administration Guidelines

Doublebase Emollient is for topical administration only and is intended for regular, continuous long-term use for skin management. Usage instructions differ based on the specific formulation.


Administration Protocol (Leave-On Gel)

Instruction Detail
Route & Dosing Topical application. Apply a sufficient amount to affected areas, smoothing the product gently in the same direction as hair growth.
Frequency Apply regularly and frequently to the affected areas as often as necessary. Specialized variants, such as Doublebase Once, are directed for once-daily use.
Age-Group Rules The Emollient Gel is suitable for adults, the elderly, infants, and children; standard application instructions apply across all age groups.

Contextual Use and Sequencing

Administration of the Emollient Gel should be integrated into daily routines and application can continue even when the skin appears normal (maintenance). The product can be used before or after washing or as a soap substitute cleanser.

Inter-product Sequencing: If applying another topical medication to the same area, do not mix the two products; apply them alternately, allowing sufficient time for the first application to be absorbed before the second is applied.

Bath Additive Dosing

For the Bath Additive formulation, the product must be shaken before use and diluted in warm water. Adults require 15 to 20 mL added to the bath water, while infants and children require 5 to 10 mL. The skin should be soaked for 10 to 20 minutes and patted dry afterward, avoiding rubbing.

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Recent Clinical Evidence

Research Evidence / Overview of Studies for Doublebase Emollient


Evidence for Symptomatic Management of Atopic Eczema and Dermatitis

The use of this emollient gel in conditions like Atopic Eczema and dermatitis was studied for in Randomized Controlled Trials (RCTs) and systematic reviews, which are relevant types of research. These studies were applied in research contexts involving fluctuating or unstable symptoms, examining patient-reported experiences. Researchers explored changes in specific outcomes linked to inflammatory or irritative states, such as validated clinical severity scales (like EASI and SCORAD), as well as patient-reported outcomes describing perceived discomfort, including itchiness and skin tightness.

Research highlights changes measured during the study period; studies monitored physiological strain or stress related to the skin barrier. Data show patterns related to self-reported assessments of pruritus and overall skin comfort. Research provides insight into short-term changes, focusing on outcomes related to physical discomfort.


Evidence for Foundational Skin Barrier Support

The emollient's role in providing foundational skin support for general dry skin was evaluated in pharmacological studies and short-term prospective trials. This research examined temporary physiological imbalance, specifically focusing on outcomes related to systemic or functional imbalance of the skin barrier. The studies monitored objective physical outcomes, such as skin hydration measured by Corneometry, and research examined the function of the skin barrier through Transepidermal Water Loss (TEWL) assessments.

Research provides insight into short-term changes, with data showing patterns related to measured stability of biophysical measurements over defined time intervals. Findings describe patterns observed in the studies with adults who have general dry skin, or dryness associated with conditions like Psoriasis and Elderly Pruritus. The findings contribute to the broader evidence landscape for emollient use.


Research on Primary Prevention in High-Risk Infants

The potential preventative use of emollients was studied for Atopic Eczema in infants and babies with a high-risk family history. The studies focused on episodes where symptoms become more noticeable, tracking the time to diagnosis of Atopic Eczema, as well as outcomes reflecting daily functioning or activity level.

Studies reported how symptoms evolved in the observed populations, but findings were mixed regarding whether an emollient regimen was associated with the eventual diagnosis rate of Atopic Eczema in the high-risk cohorts studied. One major RCT that included this product as part of a multi-product cohort did not report a significant difference in the primary prevention outcome.


What Remains Uncertain About Doublebase Emollient Evidence

Studies help show what has been observed so far, but several research limitation frames apply to the existing evidence. The evidence suggests quality varies across studies within this research field, and there is limited information for long-term outcomes, as follow-up durations were limited. Comparative evidence is lacking for certain newer emollient technologies, and findings were mixed regarding the product's use in the primary prevention of eczema in infants.

Key Studies & References

  1. Atopic eczema in under 12s: diagnosis and management (NICE guideline CG57)
  2. Severity strata for Eczema Area and Severity Index (EASI), modified EASI, Scoring Atopic Dermatitis (SCORAD), objective SCORAD, Atopic Dermatitis Severity Index and body surface area in adolescents and adults with atopic dermatitis
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Frequently Asked Questions (FAQ)

Common questions about Doublebase Emollient (FAQ)

Q: How does the action of Doublebase Emollient differ from a standard cosmetic moisturizer?

A: According to official product classification, Doublebase Emollient is categorized as a pharmaceutical preparation or medical device, which is intended for the treatment and management of dry skin conditions. This differs from a standard cosmetic moisturizer, which is typically used for general aesthetic moisturizing rather than for treating a specific skin condition.

Q: Is Doublebase Emollient classified as a medicine, a medical device, or a cosmetic product?

A: Doublebase Emollient is classified as a dermatological agent. Depending on the region and specific variant, official documents may designate the product as a Class I medical device or a pharmaceutical preparation. This classification reflects its intended role in actively managing and supporting the skin barrier for dry skin conditions.

Q: Why is it generally recommended to apply this type of product in the direction of hair growth?

A: Official instructions advise smoothing the product gently in the same direction as hair growth. The goal of applying it this way is to minimize the potential for follicular blockage and irritation on skin affected by dryness or inflammation, which aligns with standard application guidance.

Q: Is a slight stinging or burning sensation a normal experience when first using an emollient?

A: Official product information notes that local skin reactions, such as irritation or mild rashes, can occur in rare cases (affecting less than 1 in 1,000 users). When a localized reaction such as stinging or burning is suspected, official documents indicate that the appropriate course of action is to discontinue treatment.

Q: What is the distinction between Doublebase Emollient Gel and Doublebase Once Emollient?

A: The primary distinction between the two variants is the recommended frequency of use. The standard Doublebase Emollient Gel is directed for use regularly and frequently as often as necessary, according to official instructions. Doublebase Once Emollient is an advanced formulation labelled specifically for a once-daily application.

Q: How quickly can a person expect to see a reduction in dryness and itching after starting the product?

A: Official patient information does not specify an exact timeframe for symptom relief. The product is designed to provide symptomatic relief by trapping moisture and is intended to soften and protect the skin. Official documents describe that for a supportive effect, regular and frequent application of the product is intended.

Q: What are the key differences between the Doublebase Emollient Gel and the Shower Gel or Bath Additive?

A: The Gel is a leave-on preparation with a lower oil content (e.g., 15% Liquid Paraffin) intended for topical application throughout the day. In contrast, the Bath Additive has a significantly higher oil concentration (e.g., 65% Liquid Paraffin) and is designed to be diluted in water for soaking.

Q: Why are emollients used as a soap substitute instead of traditional foaming cleansers?

A: Official guidance states the product can be used as a soap substitute. It is used as a substitute to minimize the potential skin-drying and irritant effects commonly associated with foaming additives and fragrances found in ordinary cleansers and soaps.

Q: Does the emollient need to be completely absorbed into the skin to be effective?

A: The primary mechanism of action involves occlusion, where the product forms an external, protective barrier on the skin's surface. This barrier is what reduces water loss and helps the skin retain moisture. Therefore, the goal is to maintain this protective film, not necessarily to have the product completely absorbed.

Q: Why do official instructions advise against rubbing the skin vigorously when applying the product?

A: The product instructions advise smoothing the emollient gently onto the affected areas. Vigorous rubbing is generally avoided because it can lead to irritation in skin that is already dry or compromised.

Q: Is Doublebase Emollient suitable for long-term daily use as a general moisturizer?

A: Official regulatory documents indicate that the product is suitable for continuous, long-term use for skin management. It is designed for regular, first-line treatment and prophylaxis, which means it can be used to prevent dry or chapped skin conditions from returning.

Q: Does the gel formulation transition to an oily texture as it is smoothed onto the skin?

A: The product is designed with a high oil content delivered in a non-greasy gel formulation. Official documents note that the gel is designed to be relatively non-greasy and less visible after application, which may improve patient satisfaction.

Q: Is there an advantage to using a gel format over a traditional cream or ointment for certain conditions?

A: The gel formulation is recognized for supporting better patient adherence, as it is often perceived as being less visible and less greasy than traditional creams or ointments.

Q: Does Doublebase Emollient work for skin conditions other than the listed uses like psoriasis or ichthyosis?

A: According to official product literature, the emollient is indicated for the treatment and management of various dry skin conditions. This includes atopic eczema, dermatitis, psoriasis, ichthyosis (abnormal scaly skin), and pruritus (itchy skin).

Q: Is there a different way to apply the emollient on hairy areas of the body?

A: Application instructions advise smoothing the product gently onto the affected areas in the same direction as the hair grows. This is the general application method recommended for all areas, including those with hair.

Q: Is it possible to apply too much emollient at one time?

A: Instructions advise patients to apply a sufficient amount of the product to the affected area. It is also noted that patients should allow time for any excess amount to naturally soak in, implying that application should be managed to avoid a heavy surplus.

Q: What are the instructions for operating the pump dispenser on the larger bottles?

A: Instructions for pump dispensers specify turning the top anti-clockwise to unlock the unit prior to use. Additionally, the pump may need to be pressed several times to prime it for the initial application.

Q: What should a patient do if their skin condition appears to worsen after starting this product?

A: Official regulatory documents state that when a localized reaction or a worsening of the skin condition is observed, the treatment is advised to be discontinued.

Q: Does washing clothing and bedding completely remove the residue that causes the fire risk?

A: Official drug safety updates from government sources state that washing clothing and bedding may reduce the product build-up, but it may not completely remove the residue. Therefore, the associated fire hazard may still remain.

Q: What should be used to clean the bath or shower after using a Doublebase bath/shower product?

A: After using the Bath Additive or Shower Gel, official advice is to clean the surface of the bath or shower with a suitable detergent. Cleaning the surface assists in removing any residual greasiness left by the product, which helps address the potential for accidental slipping.

Q: Do the ingredients in Doublebase Emollient include common irritants like SLS or fragrances?

A: The official excipient list for the standard Doublebase Emollient Gel does not include Sodium Lauryl Sulfate (SLS) or fragrances. Additionally, patient information for the Wash Gel variant explicitly states that the product is fragrance-free.

Q: Can the use of this emollient help reduce the overall frequency of eczema flare-ups?

A: Official literature describes the product as being suitable for the prophylaxis (prevention) of dry skin conditions. This maintenance use is intended to support the skin barrier, which may assist in managing the skin against future episodes.

Q: Is it true that taking a bath in hot water can worsen dry skin conditions?

A: General patient advice found in the product literature recommends using warm, not hot, water when bathing. This is because official patient guidance indicates that hot water and long periods in the bath are associated with potentially worsening dry skin conditions.

Q: What should be done if a patient suspects the product is causing a bad reaction?

A: Official documents state that when a bad reaction is suspected, treatment is advised to be discontinued immediately. Suspected adverse reactions are advised to be reported via the appropriate national regulatory scheme.

Q: Are there any special precautions for using this product on skin that is undergoing UV light therapy?

A: Regulatory guidance for patients undergoing UVB phototherapy advises against applying emollients like Doublebase in the two hours immediately prior to treatment. Patients are generally directed to follow the specific instructions of their healthcare provider regarding this sequencing.

Q: What is the difference in ingredients between Doublebase Emollient Gel and Doublebase Bath Additive?

A: Official product information details distinct formulations for the different variants. The Gel contains 15% Liquid Paraffin and 15% Isopropyl Myristate. The Bath Additive contains a much higher oil concentration, including 65% Liquid Paraffin, and specific emulsifying excipients to ensure it dissolves when added to water.

Q: Does the product contain petroleum jelly or only liquid paraffin?

A: The active ingredients listed in the core product information are Liquid Paraffin and Isopropyl Myristate. Official documentation does not list Petroleum Jelly (also known as White Soft Paraffin) as an ingredient in the standard Gel formulation.

Q: What are the general expectations for long-term skin health when using emollients regularly?

A: The general expectation based on regulatory information is that continuous, regular use is intended to support long-term skin health. This helps maintain the skin's normal protective function and assists in the prophylaxis (prevention) of dry skin conditions.

Q: How often should the emollient be reapplied throughout the day for maximum effect?

A: Official documents state that for the best effect, the emollient should be applied regularly and as often as needed. General advice for emollients often suggests reapplication every four to six hours, or whenever the skin begins to feel dry.

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How should Doublebase Emollient be stored and disposed of?

Storage and Handling Requirements

Doublebase Emollient must be stored under specific conditions to maintain its quality and ensure safety, as defined in regulatory labeling.

Item Official Storage Requirement
Temperature Restriction Do not store the product above 25 C; it must not be frozen.
Child Safety Keep out of the sight and reach of children.
Container Integrity The container cap must be replaced (tube) or the pump locked (bottle) after each use.
Fire Hazard Do not smoke or go near naked flames during use. Fabric (clothing, bedding) that has been in contact with the product is a serious fire hazard.

Disposal and Stability

The product must not be used after the expiry date shown on the container. Disposal of any unused or expired emollient should be carried out according to the local requirements established for pharmaceutical waste. Primary regulatory documents do not specify household disposal steps or special environmental restrictions.

Attention! Always consult to a doctor or pharmacist before using pills or medicines.

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