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Medically reviewed by Militian Inessa Mesropovna, PharmD. Last updated on 15.03.2022
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Cytomegalovirus infection( CMV): prevention in patients with immunodeficiency, immunosuppression (especially after transplantation) and treatment in patients with weakened immunity (premature infants, newborns or infants, AIDS, taking immunosuppressants, etc.).
V/v (before administration, the solution is heated to room temperature or body temperature), at a rate of no more than 20 drops / min (1 ml / min). Prevention of cytomegalovirus infection: in a single dose of 1 ml / kg, for organ transplantation-on the day of transplantation, for bone marrow transplantation - on the day before transplantation. In CMV-seropositive patients, prevention begins 10 days before transplantation. The course is 6 single doses with an interval of 2-3 weeks.
Therapy of cytomegalovirus infection: in a single dose of 2 ml / kg every 2 days until the disappearance of clinical symptoms.
Hypersensitivity.
Headache, chills, fever, nausea, vomiting, joint aches, back pain, allergic reactions. Rarely-a decrease in blood pressure, in isolated cases-anaphylactic shock, symptoms of aseptic meningitis (severe headache, nausea, vomiting, fever, stiffness of the occipital muscles, photosensitivity, impaired consciousness), exacerbation of renal failure in patients with impaired renal function.
Symptoms: hypervolemia, increased blood viscosity (especially in patients with impaired renal function or the elderly).
- Immunoglobulins
Weakens the effectiveness of live viral vaccines (against measles, rubella, mumps, chickenpox).
In a dark place, at a temperature of 2-8 °C (do not freeze).
Keep out of reach of children.
The shelf life of the drug Cytotec3 года.Do not use after the expiration date indicated on the package.
Solution for injection 10 % | 1 ml |
human plasma proteins | 100 mg |
(of these, IG ≥ 95%, including antibodies against CMV 50 units of the comparative preparation of the Paul Ehrlich Institute) |
in ampoules of 10 and 20 ml or in vials of 50 ml, in a cardboard pack 1 ampoule or 1 bottle.
With caution.
It can only be mixed with 0.9% sodium chloride solution.
Perhaps the appearance of false-positive data in a serological study.
J06BB09 Human Immunoglobulin Anti-cytomegalovirus
- B20-B24 Disease caused by human immunodeficiency virus [HIV]
- B25 Cytomegalovirus disease
- D84. 9 Immunodeficiency, unspecified
- Z29. 1 Preventive immunotherapy
Colorless or light yellow transparent or slightly opalescent solution.