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Medically reviewed by Fedorchenko Olga Valeryevna, PharmD. Last updated on 2020-03-24
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Inside, swallowing whole and washing down with a sufficient amount of liquid.
The dosage regimen should be selected individually, changing it taking into account the patient's condition and his reaction to the drug. For example, it is possible to redistribute the dose of the drug: an increase in the evening and a decrease in the daytime, or the appointment of the entire daily dose in the afternoon in 1 reception.
After a significant reduction in the severity of symptoms, it is possible to reduce the dose of the drug. However, if the patient's condition worsens against the background of a dose reduction, you should immediately increase the dose of the drug to the initial level. The goal of treatment is to achieve a therapeutic effect with the use of the minimum effective dose of the drug. This is especially important in adolescents and elderly patients with unstable autonomic nervous system, in the treatment of which undesirable side effects are more often noted.
The maximum daily dose of the drug is 150 mg.
The drug Ludiomil® prescribe 25 mg 1-3 times a day or at a dose of 25-75 mg 1 time a day, depending on the severity of symptoms and the effect of treatment. If necessary, the daily dose can be gradually increased to a maximum of 150 mg, in one or several doses, depending on the tolerability and clinical effect. Efficacy and safety of treatment with Ludiomil® children and adolescents (under 18 years of age) not installed. The use of the drug Ludiomil® it is not recommended for this age group.
In elderly patients, the drug is recommended to be prescribed in smaller doses. At the beginning of treatment, the drug Ludiomil® apply at a dose of 10 mg 3 times a day or 25 mg 1 time a day. If necessary, the daily dose of the drug Ludiomil® you can slowly and gradually increase to 25 mg 3 times a day or to 75 mg 1 time a day, depending on the tolerability and clinical effect.
V/v, in the form of infusions (in the case of insufficient effect when taking the drug orally or in the case of refractory to oral therapy depression).
The dosage regimen should be selected individually, changing it taking into account the patient's condition and his reaction to the drug.
The recommended daily dose is from 25 to 100 mg.
To prepare an infusion solution from 25 to 50 mg (the contents of 1-2 amp. — 5-10 ml of concentrate), 250 ml of an isotonic solution of sodium chloride or glucose is diluted. The duration of infusions is from 1.5 to 2 hours.
In cases where a higher dose is required from 75 to 150 mg (contents 3-6 amp.), the volume of the dilution solution should be 500 ml, and the duration of infusions - from 2 to 3 hours.
As soon as there is a clear positive dynamics of symptoms (usually within 1-2 weeks), you should switch to the appointment of the drug inside.
In patients over 60 years of age, as a rule, the recommended dose for starting therapy is the contents of 1 amp. (25 mg), diluted with 250 ml of saline or glucose solution, administered as infusions for 1.5 to 2 hours. If necessary, depending on the tolerability of the drug Ludiomil® and the patient's response to treatment, the daily dose can be gradually increased to the content of 2 or 3 amp. (i.e. 50 or 75 mg), diluted from 250 to 500 ml of saline or glucose solution, administered as infusions for 2 to 3 hours.
Do not abruptly cancel the drug or sharply reduce the dose due to possible side effects.
The daily dose is 25-75 mg (can be taken once or in 3 doses). The maximum dose is 150 mg (outpatient), or 225 mg (inpatient). Depending on the clinical effect, the initial dose can be increased by 25 mg every 2 weeks. After the disappearance of the depressive syndrome, the dose is reduced to a maintenance dose of 25-50 mg per day.