Cherifer

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Medically reviewed

Marina Burgos

Last updated on 22/12/2025

This page provides general, reference-level information compiled from official medical sources. It is not a substitute for professional medical advice, diagnosis, or treatment. For decisions about your health, please consult a qualified healthcare professional.

Overview of Cherifer

The Cherifer product family is a specialized multivitamin preparation primarily categorized as a nutritional supplement, available as an Oral Solution (Syrup or Drops) or a Capsule. It is manufactured by Gruppo Medica, Inc. in the Philippines, and is generally regarded as an Over-the-Counter (OTC) product.

Property Description
Active ingredient Chlorella Growth Factor (CGF), Cyanocobalamin, Lysine, Taurine, Vitamins, Minerals
Form Oral Solution (Syrup, Drops), Capsule
Pharmacological class Multivitamins with Minerals (MIMS)
Common use Addressing nutritional deficiencies; supporting physical growth and development
Origin Derived (CGF from Chlorella), Synthetic/Natural (Vitamins, Amino Acids)

What Type of Preparation is Cherifer? (Defining Identity and Class)

Cherifer is a multicomponent nutritional supplement administered orally, positioning it within the pharmaceutical class of multivitamins with minerals. This classification indicates its intended role is to complement dietary intake, not to function as a therapeutic drug for disease treatment. The foundation of the preparation is its spectrum of essential nutrients, including the B-complex vitamins and minerals. For example, Cyanocobalamin, a synthetic form of Vitamin B12 found in the preparation, is specifically used to prevent or correct B12 deficiencies. This confirms the product’s foundational utility in ensuring the body has the necessary cofactors for vital metabolic processes.


Composition and The Role of Chlorella Growth Factor (CGF)

The product’s core composition is a differentiating factor, combining common micronutrients with specialty components, including amino acids like Lysine and Taurine, often alongside Elemental Zinc. The distinguishing element is the Chlorella Growth Factor (CGF), a derived biological substance rich in nucleotides and essential proteins harvested from the Chlorella microalgae. Chlorella extracts have been noted for the ability to promote the growth and proliferation of mammalian cells in laboratory settings. This indicates the component is utilized to provide concentrated biological resources necessary for cellular repair and rapid growth and development. The availability in different flavors, such as orange flavor, is a practical feature designed to enhance patient acceptance in the target child and adolescent population.


General Purpose: Supporting Growth and Nutritional Status

The overarching function of the Cherifer line is to address potential nutritional deficiencies in children and adolescents during their peak growth periods, which is its core market positioning. The strategic combination of B-vitamins supports optimized energy metabolism, while the CGF and amino acids provide the building blocks for tissue building and physical development. The final product is consistently aimed at improving the user's overall nutritional status, thereby establishing a robust foundation for achieving their full growth and developmental capacity.

Regulatory References

  1. NIH Cyanocobalamin Information
  2. NIH Chlorella Research

What side effects are possible with Cherifer?

The safety profile for this multicomponent nutritional supplement is based on the official regulatory documentation for its constituent parts, primarily Vitamins, Minerals, and Amino Acids.

Common and System-Based Adverse Reactions

Adverse reactions that are frequently documented for oral multivitamin and mineral preparations primarily involve the Gastrointestinal System. These commonly observed effects may include nausea, diarrhea, constipation, or stomach upset. Dermatological (skin) reactions, such as itching or a rash, are classified as uncommon reactions associated with some B-vitamin components.

Serious Adverse Reactions and Population Constraints

Serious adverse reactions are rare, but the official labeling for components like Cyanocobalamin (Vitamin B12) documents the potential for severe hypersensitivity reactions, including anaphylaxis, especially associated with non-oral administration routes. Furthermore, the use of this component is not recommended for individuals with a known hypersensitivity to Cobalt or Vitamin B12, or for patients with Leber's disease (hereditary optic atrophy), as noted in regulatory documents.

Safety Limitations and Monitoring

Regulatory safety information outlines specific limitations on use. High doses of Vitamin B12 may mask a previously unrecognized folate deficiency, and the initiation of treatment for severe deficiency states is associated with risks of cardiovascular events, such as pulmonary edema, reported early in treatment. The product, as a nutritional supplement, is not intended to treat, diagnose, prevent, or cure disease, a fundamental regulatory classification.

Overdose and Emergency Response

The official regulatory overdose profile for this multivitamin preparation with minerals is based on the documented risk of acute mineral toxicity, particularly from the iron component. Over-ingestion presents a documented risk of severe, systemic toxicity.

Documented Overdose Manifestations

Initial presentations frequently involve severe gastrointestinal symptoms, including vomiting, diarrhea, and abdominal pain, which may progress to bloody stool or hematemesis. Systemic signs can include hypotension, tachycardia, and signs of circulatory collapse, metabolic acidosis, and potential hepatic injury. The regulatory information states that overdose of iron-containing products may be fatal, necessitating immediate attention.

Required Emergency Actions

Regulatory instructions mandate that patients or caregivers seek immediate medical attention or contact a Poison Control Center upon any suspicion of overdose. This urgency is emphasized because accidental ingestion carries a documented risk of fatal toxicity in young children. Officially described management includes symptomatic and supportive treatment, gastric decontamination, and the use of the chelating agent Deferoxamine for severe systemic iron poisoning, often requiring continuous monitoring of vital signs and serum iron levels in a hospital setting.

Therapeutic Uses of Cherifer

What Cherifer Treats: Main Uses and Benefits


The preparation, generally categorized as a multivitamin nutritional supplement, offers supportive benefit across key developmental and nutritional domains. It is relevant in clinical scenarios where the patient’s primary need is focused on enhancing nutritional status and supporting physical growth, rather than treating acute, specific diseases. Multivitamin/mineral supplements are utilized to help provide recommended nutrients when intake from food alone is inadequate, which may occur during periods of poor appetite.

Therapeutic Scope and Benefits

The supplement is generally applied in situations involving inadequate dietary intake and is commonly used to help address potential nutritional deficiencies. It is relevant for managing symptomatic manifestations of nutritional gaps, such as general weakness and non-pathological fatigue, while also supporting body tissues and development.

Common usage contexts include peak growth periods in children and adolescents, managing poor eating habits (such as with picky eaters), and providing support during periods of heightened nutritional demand, like convalescence after an illness. Components are included to support the body’s nutritional requirements for tissue development and growth. This use offers supportive benefit that contributes to general well-being.

“The purpose of the supplement is to complement the diet, helping to maintain functional stability when nutrient intake is low.”


Quick Fact: Support for Low Vitality The preparation contributes micronutrients that support the body during periods of low energy, which may help patients cope more steadily with temporary fatigue related to nutritional status.

Eligibility and Restrictions for Use

The eligibility for Cherifer is strictly defined by its regulatory classification as a nutritional supplement and the population restrictions documented in its official label. The product is primarily intended for use by children and adolescents.


Populations Who Must Not Use Cherifer

Use is contraindicated and absolutely prohibited for individuals with hypersensitivity to any component of the formulation. The product is also contraindicated in patients with severe renal impairment and those with pre-existing hypervitaminosis A (an excess of Vitamin A). Furthermore, the supplement is not indicated for use by women who are pregnant or breastfeeding.


Eligibility Restrictions and Age Rules

Use is not recommended for infants and toddlers under the age of two or three years, depending on the specific formulation variant. The label advises special caution for patients with pre-existing hepatic disorders or certain metabolic diseases/imbalances. These restrictions define the specific population for whom use is permissible according to the national regulatory authority.

What should I know about interactions with other medicines?

Interactions with other medicines and products

The official interaction profile for this multivitamin and mineral preparation is based on the documented effects of its core components, primarily Zinc and Cyanocobalamin, as established in government regulatory literature. These interactions are classified as clinically significant due to the risk of reduced substance exposure.

Exposure-Modifying Interactions

Co-administration with certain medicines may reduce the absorption or serum concentration of the supplement's components.

  • Acid-Reducing Agents and Metformin: Long-term use of Proton Pump Inhibitors (PPIs), H2 Receptor Antagonists, and the diabetes medication Metformin is formally documented to reduce the absorption or serum levels of the Cyanocobalamin (Vitamin B12) component.
  • Antibiotics: Oral co-administration with Tetracycline and Quinolone antibiotics results in a mutual reduction of absorption of both the antibiotic and the Zinc component due to chelation.
  • Pharmacodynamic Considerations: The Lysine component is associated with a potential for additive effects when co-administered with Aminoglycoside antibiotics.

Interaction-Related Restrictions

Official regulatory guidance requires a mandatory time separation between this supplement and specific antibiotic classes. The Zinc component must be administered at least two hours before, or four to six hours after, oral Tetracycline or Quinolone antibiotics to mitigate the mutual reduction of exposure. Furthermore, the official profile notes that high-calcium or high-phosphorus foods, as well as large amounts of alcohol, may inhibit the absorption of key micronutrient components. Specific caution regarding the Cyanocobalamin component is officially noted for patients with Leber's hereditary optic neuropathy and those with impaired kidney function.

Mechanism of Action

Anabolic Precursor Supply and Cellular Growth

The mechanism of Cherifer involves Nutrient/Precursor Supply. Chlorella Growth Factor (CGF) provides nucleic acids and peptides, while Lysine contributes an essential amino acid. These precursors are utilized by ribosomes to accelerate protein synthesis and cellular proliferation, which are the fundamental mechanisms driving an enhanced rate of bone and muscle tissue accretion in rapidly developing tissues.


Metabolic Efficiency and Neuro-Visual Modulation

B-complex vitamins act as coenzymes for various metabolic enzymes, optimizing the conversion of dietary macronutrients into usable ATP energy. This key mechanism facilitates improved energy substrate utilization and influences processes related to appetite regulation. Concurrently, Taurine functions as a neuro-modulator, stabilizing neuronal cell membranes and regulating Ca^2+ levels essential for nervous system development. Vitamin A supports the function of rhodopsin in the retina, facilitating retinal signal transduction.

Dosage and Administration Information

How to Use Cherifer: Official Administration Guidelines

Cherifer is registered as a multicomponent nutritional supplement, and its administration is standardized according to specific label instructions concerning the route, frequency, and dose stratification. The preparation is solely for oral route administration, available as an oral solution (syrup) or a capsule.

Administration follows a daily frequency, with the regimen explicitly stratified by the user’s age group. For children, the dose is defined by specific volumes of the oral solution (e.g., 5 mL to 15 mL) or a corresponding capsule count, where the amount increases with age to match the varying nutritional requirements. Adult-specific formulations are typically taken as one capsule once daily.

Administration Conditions and Duration

To ensure proper consumption, administration is tied to mealtimes. The capsule form is typically directed to be taken with meals, while the oral solution is typically taken after meals. Furthermore, the liquid solution requires the bottle to be shaken well immediately before the required dose is measured and administered.

The product is generally intended for continuous use over an extended course (e.g., 30–60 days) to address nutritional gaps over time, rather than for acute use. A key administrative constraint is that the maximum daily dose specified for the corresponding age group must not be exceeded.

Recent Clinical Evidence

Research Evidence: Overview of Studies for Cherifer

This section provides an objective overview of the scientific evidence that exists for the primary components and intended uses of the nutritional supplement Cherifer. This summary is based on authoritative and peer-reviewed sources and describes the types of studies conducted and the parameters they measured, focusing on what research has explored so far and where scientific uncertainty remains.


Evidence for Use in Supporting Physical Growth and Development

Research exploring the components' use in physical growth has included short-term component-specific trials and foundational biological studies. These studies were applied in research contexts examining how physical parameters change over time, primarily in populations of healthy children and adolescents. Researchers monitored anthropometric outcomes (like height and weight) and other indicators of growth during defined time intervals.

Studies related to the Chlorella Growth Factor (CGF) and Lysine components report how growth parameters evolved in the observed populations. Findings describe patterns observed in studies where certain components was associated with changes in nutritional indicators. Research on the CGF component is largely foundational, meaning it often relies on pre-clinical (laboratory) or animal models to describe patterns related to cellular proliferation and growth markers.


Evidence for Addressing Dietary Gaps and Nutritional Status

Cherifer, classified as a multivitamin with minerals, was studied for its role in addressing dietary gaps. The evidence largely consists of research on the individual vitamins and minerals (such as B-complex vitamins, Iron, and Zinc) found in the product. The evidence includes systematic reviews and meta-analyses, which are high-level forms of research. Studies monitored the essential nutrients' established utility in the body.

Studies monitored changes in biochemical markers, such as serum levels of specific micronutrients (like Vitamin B12 and Zinc), in individuals with inadequate dietary intake. Research highlights changes measured during the study period, reporting that studies examined whether administering these nutrients was associated with patterns related to functional stability when nutrient consumption is low.


Evidence in Special Populations and Research Gaps

Studies have primarily monitored the preparation's components in healthy children and adolescents or general adult populations. Data for certain groups, such as those with significant chronic conditions or other special nutritional needs, remain insufficient. Evidence quality varies across studies, with some findings being mixed, especially those related to the physical growth outcomes.

A key research gap is the limited number of large-scale, long-term, randomized controlled trials that rigorously examined the combined effect of all the specific ingredients (CGF, Lysine, Vitamins, and Minerals) together in the final Cherifer product. Long-term effects and durability of outcomes are not fully established.

Key Studies & References

  1. NIH Books: Cyanocobalamin (Vitamin B12)
  2. Chlorella and Human Health: The Review of the Data from the Human Clinical Trials

Frequently Asked Questions (FAQ)

Common questions about Cherifer (FAQ)

Q: What is the main reason healthcare professionals recommend Cherifer?

A: Official product information describes the preparation's function as providing essential nutrients to address nutritional deficiencies. The product is officially described as providing essential vitamins, minerals, and growth factors intended to support physical development during peak periods.


Q: How long does it usually take for a person to notice the effects of Cherifer?

A: According to the official product information, the supplement is intended for continuous use over an extended course, typically 30 to 60 days. The continuous use period is described as a strategy for addressing potential nutritional gaps over time, rather than seeking immediate or acute effects.


Q: What are the most common things people say they experience when taking Cherifer?

A: Official documents describe the preparation's function as providing nutritional support intended to influence processes related to appetite, vision, metabolism, and physical development. The focus of the product is on nutritional benefits rather than immediate sensations.


Q: Can Cherifer be taken by people with certain food allergies?

A: The official product labeling states that the use of Cherifer is contraindicated and should be avoided by individuals with a known hypersensitivity or allergy to any component contained in the formulation. Individuals with known allergies may wish to review the full ingredient list.


Q: Does Cherifer interact with common over-the-counter cold and flu medications?

A: The official interaction profile lists specific types of medicines, such as Acid-Reducing Agents (like antacids) and certain Antibiotics, that may reduce the absorption of the supplement’s components. The official product profile details specific interactions, and non-listed cold or flu medicines are not featured in the documented warnings.


Q: Can Cherifer be taken with food, or does it need to be taken on an empty stomach?

A: Official administration instructions specify that the capsule form is typically directed to be taken with meals. Conversely, the oral solution (syrup or drops) is generally instructed to be taken after meals.


Q: Can individuals with specific health conditions, like diabetes, use Cherifer?

A: Official labeling advises that special caution should be exercised for patients with pre-existing hepatic disorders or certain metabolic diseases/imbalances. Official guidance notes that individuals with metabolic diseases or imbalances typically require a discussion with a healthcare provider regarding the product's suitability.


Q: Can Cherifer be taken alongside herbal supplements?

A: Regulatory guidance describes the importance of informing a healthcare professional before combining the supplement with other vitamins, minerals, or herbal supplements. This is noted to avoid potential combined effects or unintended reductions in absorption.


Q: What is the overall safety profile of Chlorella Growth Factor as an ingredient?

A: The preparation's official safety profile is described based on the documented effects of its constituent parts. Common adverse reactions documented for multivitamin preparations, such as nausea, diarrhea, or stomach upset, align with the known effects sometimes associated with the Chlorella Growth Factor component.


Q: Does Cherifer affect appetite?

A: The product's intended function, as officially described, is to influence the body’s processes related to appetite. This is one of the functions listed for the nutritional preparation.


Q: Is there a difference in ingredients between Cherifer capsules and Cherifer syrup/drops?

A: Yes, regulatory documentation shows that different product forms, such as the syrup, drops, or specific capsule lines, contain variations in their component list. These variations may include different amounts of vitamins or the presence of additional ingredients like Zinc or Ginseng.


Q: Is there a maximum recommended period for taking Cherifer?

A: Official labeling for certain formulations notes that the duration of continuous use should not exceed three months without a medical re-evaluation. The product is intended for extended, rather than indefinite, use to address nutritional gaps.


Q: Does taking Cherifer require any special diet or lifestyle changes?

A: The official product profile notes that consumption of high-calcium or high-phosphorus foods, as well as large amounts of alcohol, may inhibit the absorption of key micronutrient components. These factors are points for consideration during the period of use.


Q: What should a person do if they suspect a mild side effect from Cherifer?

A: Official labeling states that if persistent adverse reactions occur, discontinuing use of the supplement is advised. This action is generally followed by consulting a healthcare provider for further guidance.


Q: Are there any specific components in Cherifer that are known to cause bright yellow urine?

A: Multivitamin preparations contain B-complex vitamins, and specific components like Riboflavin (Vitamin B2) are commonly known to cause a harmless change in urine color. This change is an expected pattern that may cause the urine to appear bright yellow or orange.


Q: Does Cherifer contain B vitamins?

A: Yes, the product is classified as a multivitamin preparation and includes a spectrum of B-complex vitamins. These include essential nutrients such as Thiamine (B1), Riboflavin (B2), Pyridoxine (B6), and Cyanocobalamin (B12).


Q: Can Cherifer be mixed with juice or milk?

A: Official administration instructions for specific oral solutions, such as infant drop formulations, describe the product as being permitted to be mixed with milk, fruit juices, or other liquids prior to administration to aid consumption.


Q: Is Cherifer commonly used in specific non-US countries?

A: Official documents indicate that the product's origin is the Philippines, where it is widely marketed and used. Regulatory documents indicate its origin, and the product is listed by retailers in various international markets.


Q: Why is Cherifer often discussed in online forums related to growth and development?

A: The supplement is officially classified and positioned for its role in addressing nutritional deficiencies and supporting physical growth and development in the target population. This official positioning naturally leads to public discussions related to these topics.

How should Cherifer be stored and disposed of?

The official regulatory guidelines for Cherifer address environmental stability, child safety, and proper discarding procedures.

Storage Conditions

The product must be stored at controlled room temperature, maintaining conditions that do not exceed 30 C. To preserve the potency of its vitamin components, the container must be protected from direct heat and sunlight, and freezing is prohibited. The container must be kept tightly closed to prevent exposure to moisture and air.

Child Safety and Disposal

Cherifer must be kept out of the reach and sight of children to prevent accidental ingestion. Disposal must follow regulatory pharmaceutical waste guidelines. The preferred method is using a drug take-back program. If this is unavailable, the product must be mixed with an undesirable substance, placed in a sealed container, and discarded in the household trash. It is explicitly required not to flush the product down the toilet or pour it down the drain.

Attention! Always consult to a doctor or pharmacist before using pills or medicines.

Equivalent of Cherifer found in:

A-Z Index: