Benol

Benol

Nifuroxazide

Diarrhea (acute and chronic) caused by Gram-positive (staphylococci and streptococci), as well as some Gram-negative (Salmonella, Shigella, Klebsiella, Escherichia coli) bacteria, diarrhea with food intoxication, appendicitis, chronic autoimmune gastritis, diarrhea caused by antibiotic therapy, changes in the natural bacterial flora of the large intestine of various etiologies, diseases accompanied by diarrhea.

Toxic diarrhea caused by Gram-negative bacteria (Salmonella, Shigella, Klebsiella, Escherichia coli) in children older than 2 months.

Inside. Tablets: adults and children over 6 years — 2 tablets (200 mg) 4 times a day every 6 hours. The course is 6 days.

Suspension: adults and children over 6 years - 5 ml (1 scoop) 4 times a day every 6 hours, children 2-6 months-2.5 ml 2 times a day or 5 ml 2 times a day, from 6 months to 6 years — 5 ml 3 times a day every 8 hours.

In the case of diarrhea associated with sepsis, Nifuroxazide can not be used as a single drug, because it is not absorbed from the intestine and its effect is limited to the gastrointestinal tract.

Hypersensitivity (including to derivatives of 5-nitrofuran), in children — prematurity and age less than 2 months.

Allergic reactions (rash, urticaria, Quincke's edema, anaphylactic shock), nausea, vomiting.

Signs of overdose in humans are unknown. In case of overdose, gastric lavage and symptomatic therapy are recommended.

It is effective against Gram-positive (staphylococci, streptococci) and some Gram-negative (Salmonella, Shigella, Klebsiella, Escherichia coli) bacteria, does not affect the composition of the normal microflora of the large intestine. Presumably inhibits the activity of dehydrogenases and protein synthesis in bacterial cells. It does not cause drug-resistant strains, as well as cross-resistance with other antibacterial drugs. The effectiveness of the action does not depend on the pH in the intestinal lumen, on the sensitivity of microorganisms to antibiotics. The drug acts exclusively in the intestinal lumen, since it is practically not absorbed from the digestive tract

After ingestion, it is practically not absorbed from the gastrointestinal tract into the circulatory system and does not have a general effect on the body. It is excreted in the feces.

• Other synthetic antibacterial agents

Since the drug is not absorbed from the gastrointestinal tract, the possibility of interaction with other drugs is unlikely.