Components:
Method of action:
Treatment option:
Medically reviewed by Kovalenko Svetlana Olegovna, PharmD. Last updated on 24.03.2022
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Top 20 medicines with the same components:
Pain syndrome of various etiologies:
headache,
migraine pain,
toothache,
neuralgia,
myalgia,
algodismenorrhea,
postoperative pain,
renal and biliary colic (in combination with antispasmodics),
feverish conditions in infectious and inflammatory diseases.
Inside, adults — 1 table. 2-3 times a day after meals. The maximum single dose is 1 g (2 tablets), the daily dose is 3 g (6 tablets). With prolonged (more than a week) use of the drug, it is necessary to monitor the picture of peripheral blood and the functional state of the liver.
Children are prescribed 5-10 mg/kg of body weight 3-4 times a day for no more than 3 days (after grinding the tablet).
Do not use (without consulting a doctor) for more than 3 days when prescribed as an antipyretic and more than 5 days when prescribed as an analgesic.
hypersensitivity to pyrazolones derivatives (phenylbutazone, tribuson),
bronchial asthma,
diseases accompanied by bronchospasm,
"aspirin asthma»,
suppression of hematopoiesis (agranulocytosis, neutropenia, leukopenia),
severe hepatic or renal impairment,
diseases of the blood,
hereditary hemolytic anemia associated with glucose-6-phosphate dehydrogenase deficiency,
pregnancy (especially in the first trimester and in the last 6 weeks),
lactation period.
With caution — infancy (up to 3 months).
Allergic reactions: skin rash, Quincke's edema, rarely-anaphylactic shock, toxic epidermal necrolysis (Lyell's syndrome), in rare cases — Stevens-Johnson syndrome.
With prolonged use, leukopenia, thrombocytopenia, agranulocytosis may occur.
With a tendency to bronchospasm, it is possible to provoke an attack, reduce blood pressure.
Possible renal dysfunction, oliguria, anuria, proteinuria, interstitial nephritis, urine staining in red due to the release of a metabolite.
All side (unusual) effects, including those not mentioned above, should be reported to the attending physician and stop taking the drug.
Symptoms: with prolonged use of the drug (more than 7 days) in large doses — nausea, vomiting, gastralgia, oliguria, hypothermia, decreased blood pressure, tachycardia, shortness of breath, tinnitus, drowsiness, delirium, impaired consciousness, agranulocytosis, hemorrhagic syndrome, acute renal and/or liver failure, convulsions, paralysis of the respiratory muscles.
Treatment: induce vomiting, do gastric lavage, take saline laxatives, activated charcoal. In the conditions of a medical institution — forced diuresis, hemodialysis, with the development of convulsive syndrome-intravenous administration of diazepam and barbiturates.
Metamizole sodium is a pyrazolone derivative. It has analgesic, antipyretic and weak anti-inflammatory effects, the mechanism of which is associated with the inhibition of the synthesis of PG. Pharmacological action develops in 20-40 minutes after taking the drug and reaches a maximum in 2 hours.
- NSAIDs-Pyrazolones
The simultaneous use of Analgin with other non-narcotic analgesics can lead to a mutual increase in toxic effects.
Tricyclic antidepressants, oral contraceptives, and allopurinol disrupt the metabolism of metamizole in the liver and increase its toxicity.
Barbiturates and phenylbutazone weaken the effect of analgin.
Analgin enhances the effects of alcoholic beverages.
Radiopaque substances, colloidal blood substitutes and penicillin should not be used during treatment with metamizole.
Metamizole, displacing oral hypoglycemic drugs, indirect anticoagulants, corticosteroids and indomethacin from the protein bond, increases their activity.
Simultaneous use of Analgin with cyclosporine reduces the level of the latter in the blood. Thiamazole and sarcolysin increase the risk of developing leukopenia. The effect is enhanced by codeine, propranolol (slows down inactivation).
Sedatives and tranquilizers enhance the analgesic effect of analgin.
In a dry, dark place.
Keep out of reach of children.
Shelf life of the drug Analgin5 лет.Do not use after the expiration date indicated on the package.
Instructions for medical use Анальгин - инструкция по медицинскому применению - РУ № ЛСР-007019/08 от 2008-09-02Анальгин - инструкция по медицинскому применению - РУ № ЛС-002585 от 2011-12-29
Анальгин - инструкция по медицинскому применению - РУ № Р N001942/01 от 2006-12-08
Анальгин - инструкция по медицинскому применению - РУ № Р N003134/01 от 2009-07-15
Анальгин - инструкция по медицинскому применению - РУ № Р N001051/02 от 2016-08-22
Анальгин - инструкция по медицинскому применению - РУ № ЛС-002585 от 2006-12-29
Анальгин - инструкция по медицинскому применению - РУ № Р N001942/01 от 2017-07-27
Анальгин - инструкция по медицинскому применению - РУ № Р N001286/02 от 2009-02-05
Анальгин - инструкция по медицинскому применению - РУ № Р N001051/01 от 2018-01-18
Анальгин - инструкция по медицинскому применению - РУ № ЛС-000487 от 2015-05-07
Анальгин - инструкция по медицинскому применению - РУ № Р N001780/02 от 2008-11-20
Анальгин - инструкция по медицинскому применению - РУ № Р N001286/01 от 2008-11-18
Анальгин - инструкция по медицинскому применению - РУ № Р N000597/01 от 2012-02-29
Анальгин - инструкция по медицинскому применению - РУ № Р N003281/01 от 2009-04-07
Анальгин - инструкция по медицинскому применению - РУ № ЛС-000487 от 2010-05-31
Анальгин - инструкция по медицинскому применению - РУ № Р N001780/01 от 2015-08-12
Pills | 1 table. |
active substance | |
metamizole sodium (analgin) | 0.5 g |
excipients: potato starch, sugar, calcium stearate, talc |
in a contour cell-free or cell-free package of 10 pcs. , in a pack of cardboard 1, 2, 3 or 5 packages.
Contraindicated during pregnancy (especially in the first trimester and in the last 6 weeks). Breastfeeding should be discontinued for the duration of treatment.
In patients suffering from bronchial asthma and pollinosis, it is possible to develop hypersensitivity reactions.
With prolonged use (more than 7 days), it is necessary to monitor the picture of peripheral blood.
Do not use to relieve acute abdominal pain (until the causes are clarified).
In the treatment of children under 5 years of age and patients receiving cytostatic agents, the use of metamizole sodium should be carried out only under the supervision of a doctor.
Special care is required when prescribing to patients who abuse alcoholic beverages.
Children under 2 years of age are recommended to use children's dosage forms.
Children and adolescents under 18 years of age should only be used as prescribed by a doctor.
N02BB02 Metamizole sodium
- G43 Migraine
- K08. 8. 0* Toothache
- K82. 8. 0 * Dyskinesia of the gallbladder and bile ducts
- M79. 1 Myalgia
- M79. 2 Neuralgia and neuritis, unspecified
- N23 Renal colic, unspecified
- N94. 0 Pain in the middle of the menstrual cycle
- N94. 6 Dysmenorrhea, unspecified
- R50 Fever of unknown origin
- R51 Headache
- R52. 9 Pain, unspecified
- Z100* CLASS XXII Surgical Practice
Tablets of white or slightly yellowish color, flat-cylindrical, with a risk and a chamfer, a bitter taste.