Alcacyl

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Alcacyl

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Medically reviewed

Marina Burgos

Last updated on 10/01/2026

This page provides general, reference-level information compiled from official medical sources. It is not a substitute for professional medical advice, diagnosis, or treatment. For decisions about your health, please consult a qualified healthcare professional.

Overview of Alcacyl

Quick Facts

Property Description
Active Ingredient Aspirin, Carbasalate Calcium
Form Effervescent Tablets / Soluble Granules
Pharmacological Class Nonsteroidal Anti-inflammatory Drug (NSAID)
Common Use Pain relief and fever reduction
Origin Synthetic Compound

Identity and Pharmacological Classification of Alcacyl

Alcacyl is defined as a combination medicine belonging to the Nonsteroidal Anti-inflammatory Drug (NSAID) class, chemically categorized within the Salicylate derivative group. This synthetic compound is utilized for its dual systemic effects: pain relief and temperature regulation. Its core actions are classified as an analgesic and antipyretic.

Its identity is rooted in its relationship with Acetylsalicylic acid (Aspirin), distinguishing it from single-active ingredient preparations. This defining classification establishes its mechanism: primarily targeting the chemical processes of inflammation and fever throughout the body, providing systemic relief often sought in cases of general discomfort.


Active Components and Dosage Form

The active ingredients in Alcacyl are Aspirin (Acetylsalicylic acid) and the highly water-soluble complex salt, Carbasalate Calcium. The medicine is designed for oral administration and is typically presented as effervescent tablets or soluble granules, promoting quick dissolution.

This specific composition leverages Carbasalate Calcium (Calcium acetylsalicylate carbamide), which is engineered to achieve superior water solubility compared to standard Aspirin powder. This characteristic feature defines the physical form of the medicine, facilitating easy preparation as a solution, which aids in the rapid absorption of the active components.


General Therapeutic Purpose

The general purpose of Alcacyl is to provide effective symptomatic treatment, functioning primarily as an analgesic (pain reliever) and antipyretic (fever reducer). The preparation is fundamentally intended for the alleviation of mild-to-moderate pain and the reduction of elevated body temperature, or febrile conditions.

The utility of the medicine is rooted in its ability to inhibit the synthesis of Prostaglandins, which are chemical compounds that signal pain and promote fever, providing a direct systemic effect. This action ensures that the preparation can be employed for general discomfort and temperature management where a non-opioid, non-selective chemical mediator inhibitor is required.

Regulatory References

  1. WHO ATC/DDD Toolkit

What side effects are possible with Alcacyl?

Possible Side Effects and Safety Information

The officially documented safety profile for Alcacyl is primarily structured by the regulatory classification of its active ingredients, belonging to the Nonsteroidal Anti-inflammatory Drug (NSAID) class. Adverse reactions are grouped by frequency and the specific body systems affected, based on authoritative government sources.

System-Organ Classes and Frequencies

The most commonly listed adverse reactions relate to the Gastrointestinal Disorders system, including nausea, vomiting, stomach pain, and heartburn. Increased bleeding time and minor hemorrhage risk are also categorized as common effects. Less commonly documented effects include tinnitus (ringing in the ears) and hearing loss, which are sometimes associated with higher exposure levels. Regulatory documents also classify effects on the Nervous System (headache, dizziness) and the Immune System (allergic reactions).

Serious Adverse Reactions and Safety Constraints

Serious adverse reactions explicitly listed in regulatory labeling include severe gastrointestinal bleeding, ulceration, and perforation. The safety profile mandates specific constraints for certain populations. The product is not for use in children or teenagers recovering from viral infections due to the potential association with Reye's Syndrome, a rare but severe illness. Older adults are cited as having a higher potential for serious gastrointestinal events. Furthermore, the medicine is generally contraindicated in individuals with active bleeding disorders, severe kidney or liver disease, and during the third trimester of pregnancy.

Overdose and Emergency Response

Alcacyl Overdose and When to Seek Help

The substance name "Alcacyl" is associated in a non-regulatory context with compounds from the acyl-carnitine class, which is not a standard, publicly regulated drug product with an official overdose profile in major governmental databases. Therefore, specific regulatory statements regarding the signs, symptoms, or mandatory emergency procedures for an overdose of a registered drug called "Alcacyl" are not available from major health authorities.

However, a common drug product with a similar name in some regions is an aspirin (acetylsalicylic acid) combination. If this product contains aspirin or a related salicylate, overdose symptoms are well-documented and require immediate medical attention.

Urgent Signs of Salicylate Overdose (if applicable to product formula):

  • Early symptoms may include ringing in the ears (tinnitus), nausea, vomiting, rapid breathing (hyperventilation), and sweating.
  • Severe symptoms can involve agitation, confusion, fever, seizures, drowsiness, and difficulty breathing. Serious poisoning may lead to metabolic acidosis, pulmonary edema, and coma.

Action Required:

If any signs of severe intoxication or overdose are suspected, or if a high dose of a product containing aspirin or salicylates has been taken, seek emergency medical assistance immediately. Do not wait for severe symptoms to develop. Contacting emergency services or a poison control center is a critical first step to ensure timely treatment, which may include activated charcoal, intravenous fluids, and in severe cases, hemodialysis to remove the substance from the blood.

Therapeutic Uses of Alcacyl

What Alcacyl treats: main uses and benefits

Alcacyl is relevant in contexts marked by increased discomfort or tension, specifically addressing symptoms related to physical discomfort and systemic imbalance associated with temporary illness. As a preparation containing these active ingredients, it is commonly used to help with fever reduction and the easing of mild to moderate pain. The therapeutic focus is generally aligned with two core areas of symptomatic management.

The medicine is used for managing conditions presenting with acute or episodic manifestations, including common headache, toothache, muscle aches (myalgia), menstrual cramps, and elevated body temperature associated with colds or flu.

“Its role is supporting symptom management and easing the overall symptom load during periods of heightened discomfort.”

Relief for Mild-to-Moderate Aches and Pains

This domain applies across therapeutic areas where short-term symptom management is appropriate for common, non-chronic discomfort. Alcacyl is commonly used across conditions presenting with acute or episodic manifestations of pain. It provides support to help ease the overall symptom load, and may assist with maintaining functional stability when symptoms interfere with routine activities.

Quick Fact: Relief for Mild-to-Moderate Pain

Scope Scenario Benefit
Pain Episodic headache, toothache, muscle aches Supports functional stability
Fever Cold and flu-like symptoms May help ease systemic discomfort
Severity Acute or recurrent symptoms May contribute to easing symptom fluctuations

Regulatory References

  1. MedlinePlus Drug Information

Eligibility and Restrictions for Use

Eligibility Map: Who Can and Cannot Use Alcacyl — Official Regulatory Information

The official population eligibility for Alcacyl (Carbasalate Calcium / Aspirin) is strictly defined by regulatory documents, establishing absolute contraindications across several domains.

Category Eligibility Rule
Contraindicated Populations Hypersensitivity to Acetylsalicylic acid or other NSAIDs; active gastrointestinal ulcers or haemorrhages; coagulation disorders; severe hepatic or renal insufficiency; Methotrexate at doses greater than 15 mg per week.
Age-Related Rules Use is contraindicated in children under 12 years for analgesic strengths and is not recommended for adolescents under 16 years, unless specifically indicated.
Pregnancy/Lactation Status Contraindicated during the third trimester of pregnancy (at analgesic doses) and during breast-feeding.

Eligibility-Related Restrictions

Use requires close medical monitoring or caution in patients with slight or moderate hepatic or renal impairment, a history of gastric complaints, or pre-existing conditions like asthma bronchiale or allergic rhinitis. The medicine is also restricted shortly before or after the extraction of teeth.


Connection to the Overall Eligibility Profile

Regulatory documents define who can and cannot use the medicine by establishing absolute prohibitions for populations with active bleeding risk, severe organ failure, and known NSAID hypersensitivity. Conditional use rules apply to groups with milder organ impairment, ensuring the medicine is only used when the documented risks are managed.

What should I know about interactions with other medicines?

Interactions with Other Medicines and Products

This section outlines interactions officially documented in government regulatory sources, strictly regarding co-administration risks.


Formally Documented Contraindications

Co-administration of Alcacyl, which contains Aspirin, is strictly contraindicated with certain medicines due to severe interaction risks identified in regulatory labels:

  • Methotrexate at doses of 15 mg per week or greater.
  • Uricosuric Agents (e.g., Probenecid, Sulfinpyrazone) as Alcacyl component antagonizes their therapeutic effect.
  • High-dose parenteral Heparin in patients 65 years of age and older.

Clinically Significant Interaction Patterns

Interaction Type Interacting Substances (Examples) Official Regulatory Finding
Increased Bleeding Risk Oral Anticoagulants, SSRIs, Alcohol Additive pharmacodynamic effect; increased risk of hemorrhage.
Altered Drug Exposure Valproic Acid, Phenytoin, Lithium Increased free plasma concentration of the co-administered drug due to clearance inhibition or protein binding displacement.
Therapeutic Interference Ibuprofen (Other NSAID) May interfere with the antiplatelet effect of Aspirin if not dosed with required time separation.

Interaction-Related Restrictions and Timing Rules

Regulatory documents mandate specific spacing to manage certain interactions. To avoid interference with antiplatelet effects, Ibuprofen must be administered at least 8 hours before or 30 minutes after the immediate-release Aspirin dose. Additionally, the use of Alcohol is restricted due to a documented increase in gastrointestinal bleeding risk.

Mechanism of Action

How Alcacyl Works: Mechanism of Action

Alcacyl's mechanism involves two core components that modulate pathways related to nociception, inflammatory signaling, and thermoregulation. The Acetylsalicylic Acid component functions as an irreversible, non-selective inhibitor of Cyclooxygenase (COX) enzymes (COX-1 and COX-2). This chemical modification prevents the synthesis of Prostaglandins, which are key mediators of inflammatory responses and hypothalamic temperature elevation. The resulting physiological changes are a systemic modulation of inflammatory signaling and the lowering of the body's temperature set-point.

A distinct action of Acetylsalicylic Acid is the irreversible acetylation of platelet COX-1, which suppresses the formation of Thromboxane A2 for the life of the platelet, resulting in altered platelet activation and a reduced capacity for aggregation. The Paracetamol component contributes primarily through central action, inhibiting CNS COX variants and modulating descending inhibitory pathways, leading to central modulation of nociceptive and thermoregulatory signaling within the brain and spinal cord.

Dosage and Administration Information

Administration Guidelines for Alcacyl

The correct use of the medicine is structured by specific rules for preparation, timing, and dosage adherence. Alcacyl, which contains calcium carbasalate (equivalent to acetylsalicylic acid) and aluminum hydroxide, is administered by the oral route.

Dosing and Preparation

Administration Component Instruction
Route of Administration Oral.
Preparation The medicine must be made up with plenty of liquid (for the tablet or powder forms).
Dosing Schedule Patients must follow the dosage given in the package leaflet or prescribed by a doctor.
Timing with Meals The medicine should be taken after a meal if possible.
Separation from Other Medicines Due to the presence of aluminum hydroxide, this medicine must not be taken at the same time as other medicines, but instead approximately 2 hours apart.

Procedural Structure

The administration process requires the user to first take the medicine (tablet or powder) and ensure it is properly prepared by making it up with plenty of liquid. Ingesting the medicine is preferably done after a meal. A mandatory procedural constraint is the required two-hour interval when taking other medicines simultaneously, to avoid potential binding interactions of the aluminum hydroxide component. This structure ensures regulated use.

Recent Clinical Evidence

Research Evidence / Overview of Studies for Alcacyl

Evidence Base for Mild-to-Moderate Pain Relief

Research related to Alcacyl's active components was studied for conditions characterized by fluctuating or episodic manifestations of physical discomfort, such as headaches, muscular aches, and dental pain. The evidence primarily stems from short-term Randomized Controlled Trials (RCTs), many of which are synthesized by Meta-Analyses. These studies were applied in research contexts involving fluctuating or unstable symptoms, with researchers monitoring patient-reported outcomes describing perceived discomfort.

In these acute research scenarios, studies explored how symptoms changed over defined time intervals. Findings describe patterns observed in the studies, which included measurements of the change in pain intensity scores recorded by participants over the first few hours following a single dose. Studies examined formulations designed for rapid dissolution, and evidence contributes to understanding symptom patterns, particularly focusing on the time to the observed change in symptoms.

Evidence Base for Fever Reduction

Research related to Alcacyl’s active component has been evaluated in studies monitoring changes in elevated body temperature, relying heavily on the Well-Established Use literature for Aspirin, supplemented by some specific trials. Research was evaluated in studies examining temporary physiological imbalance. The studies monitored the observed populations and reported on patterns related to the recorded temperature measurements over the first several hours after administration. This evidence contributes to the broader scientific landscape related to research into systemic changes with this class of medication.

Evidence Gaps and Areas of Uncertainty

Research is still ongoing in many areas. The certainty remains low for certain aspects due to several research limitation frames. For example, the comparative evidence is lacking when evaluating this specific effervescent formulation directly against all other contemporary, non-prescription analgesic combinations. Furthermore, evidence is limited regarding its use in conditions characterized by functional limitations outside of acute, temporary episodes. The follow-up durations were limited across the major trials that support the non-prescription use of this medicine.

Key Studies & References

  1. World Health Organization (WHO) Anatomical Therapeutic Chemical (ATC) Classification System - N02BA01 Acetylsalicylic acid
  2. National Institute for Health and Care Excellence (NICE): Headache - assessment and management of headache in children and young people

Frequently Asked Questions (FAQ)

Common questions about Alcacyl (FAQ)

Q: Is Alcacyl a prescription medication or can I buy it over the counter?

Alcacyl is generally classified in regulatory documents as a non-prescription, or over-the-counter (OTC), medicine. It is intended for the self-medication of mild symptoms, such as temporary aches and fevers. This classification determines how the medicine is typically acquired and used.

Q: Does Alcacyl help with pain other than what is listed in its main uses?

The approved regulatory documents strictly limit the use of Alcacyl to the relief of mild-to-moderate pain and fever. These are the specific therapeutic indications authorized by government bodies. Its use beyond these defined conditions is not covered within the scope of the official product labeling.

Q: How long does it usually take for Alcacyl to start working?

Official information indicates that Alcacyl is designed for rapid symptom change. Due to its soluble formulation, the active ingredient is quickly absorbed into the body. Studies show that maximum concentration (Tmax), which often corresponds to the onset of action, can be reached within 15 to 45 minutes of administration.

Q: Can Alcacyl be taken for a long period of time?

Official guidelines generally restrict the self-administration of this medicine to a short duration, typically a maximum of 3 to 5 consecutive days. Regulatory warnings advise against prolonged use because it carries a heightened potential for serious adverse effects, particularly severe gastrointestinal issues.

Q: What should I do if I miss a scheduled time to use Alcacyl?

Official instructions for a missed dose state that the next dose should be taken as originally scheduled. The labeling specifies avoiding a double dose to compensate for the missed one.

Q: Are there any common foods or drinks that interact with Alcacyl?

Regulatory documents include a specific warning against the consumption of alcohol due to a documented increase in the risk of gastrointestinal bleeding. However, no other specific food or non-alcoholic drink interactions are typically listed as clinically significant in major regulatory documents for this medicine.

Q: Does Alcacyl cause drowsiness or affect my ability to drive?

The regulatory label states that side effects like dizziness or headache may occur as part of the known adverse reaction profile. If side effects such as dizziness or headache occur, regulatory guidance suggests caution when performing tasks that require full mental alertness, such as driving or operating machinery.

Q: Is there any research evidence on Alcacyl's use in older adults?

Regulatory documents provide important safety information regarding older adults. These warnings state that this population has a higher documented risk of serious adverse reactions, especially severe gastrointestinal events. Because of this increased risk, regulatory documents advise that caution and medical consultation are important considerations when using the medicine.

Q: What happens if I use Alcacyl more often than described in the directions?

Using the medicine more often than directed increases the risk of serious adverse reactions. Regulatory overdose information indicates this could lead to issues like severe gastrointestinal bleeding or signs of toxicity, such as tinnitus (ringing in the ears) or hearing loss.

Q: Is the list of side effects for Alcacyl complete, or are there others?

The list provided contains adverse reactions known and documented by regulatory bodies based on research and surveillance. Patients are consistently advised in official documents to report any new or unexpected side effects that they experience to their healthcare provider or the relevant regulatory authority.

Q: How is Alcacyl different from standard aspirin?

Alcacyl’s key difference lies in its composition and form. It contains the highly water-soluble salt, Carbasalate Calcium, which is designed to promote quick dissolution. This composition facilitates more rapid absorption compared to using standard acetylsalicylic acid powder alone.

Q: Can people with high blood pressure use Alcacyl?

Official warnings note that patients with pre-existing conditions that affect the heart or blood pressure should proceed with caution and medical consultation. This is because non-steroidal anti-inflammatory drugs (NSAIDs) may cause fluid retention, a factor that can affect cardiovascular health.

Q: Does Alcacyl interact with herbal supplements?

Regulatory documents focus on listing known interactions with specific prescription medicines. However, it is generally noted that users should inform their doctor or healthcare provider of all co-administered products, including herbal supplements, to manage potential unforeseen risks.

Q: Is it true that Alcacyl is often used for certain types of chronic inflammation?

Alcacyl is officially indicated only for the symptomatic treatment of mild-to-moderate pain and fever. Its approved use, as defined by regulatory bodies, is strictly limited to managing acute, temporary episodes. Evidence does not support its general use for chronic inflammatory conditions.

Q: Can Alcacyl be crushed or split if it is a tablet form?

The medication is formulated as an effervescent tablet or soluble granule. Regulatory guidance requires that it be dissolved in liquid prior to ingestion. The official directions for its specific route of administration must be followed exactly.

Q: Is Alcacyl a habit-forming medicine?

Alcacyl is not classified as a controlled substance by regulatory bodies in countries like the US. It is an NSAID and is therefore not generally associated with drug dependence or habit-forming potential.

Q: Does using Alcacyl affect the results of any common lab tests?

Regulatory interaction documents state that this medicine may interfere with certain laboratory tests. It is particularly known to affect those tests monitoring bleeding time. The labeling emphasizes the need to inform the healthcare professional of use prior to undergoing any laboratory testing.

Q: What should I look for in the medicine's packaging to confirm I have the correct drug, Alcacyl?

The official label includes the full product name, the correct strength of the active ingredients (Aspirin/Carbasalate Calcium), and the correct pharmaceutical form (effervescent tablet or soluble granule) for identification purposes. This information is key to confirming the correct drug.

Q: Can Alcacyl cause changes in mood or anxiety?

The documented adverse effects profile is structured by organ system. While effects on the Nervous System (like dizziness or headache) are listed, the regulatory safety profile does not typically include changes to mood or anxiety as documented side effects.

Q: What official body approved Alcacyl for use?

The medicine was approved for use by the relevant national regulatory authority in the country where it is marketed. This is the government body responsible for reviewing the safety and efficacy data before authorizing medicinal products.

Q: Is Alcacyl known to interact with caffeine?

Official regulatory interaction lists typically focus on prescription medicines and other major co-administered substances. Caution is noted when taking other products containing caffeine, as co-administration could potentially affect the body's response.

Q: Are there specific patient groups that studies on Alcacyl excluded?

Clinical studies often exclude patient groups that align with the medicine's contraindications. Examples include individuals with active bleeding disorders, severe liver or kidney disease, and children under the age of 12.

Q: Does the form of Alcacyl (e.g., tablet vs. liquid) change how quickly it works?

Yes, the formulation significantly impacts its performance. The effervescent or soluble form of Alcacyl is specifically designed to promote rapid dissolution and quick absorption of the active ingredient. This feature is intended to help achieve faster symptom changes compared to a standard, non-soluble tablet.

Q: What is the shelf life of Alcacyl after I purchase it?

The required shelf life, which dictates the stability of the medicine, is specific to the product batch. This date is officially determined and printed on the packaging as the expiration date. The regulatory guidance specifies that the medicine should not be used past this date.

Q: Does Alcacyl interfere with birth control pills?

Regulatory documents that detail known drug interactions do not list any documented interference between this medicine and the efficacy of hormonal birth control pills.

Q: Is it possible to become resistant to the effects of Alcacyl over time?

Regulatory information does not indicate that the body develops resistance, commonly known as tolerance, to the analgesic or antipyretic effects of this medication over its recommended, short period of use.

Q: Is Alcacyl ever used in combination with other medicines for better effect?

The regulatory label for Alcacyl includes a specific warning related to the aluminum hydroxide component. The regulatory label specifies that Alcacyl should be taken approximately 2 hours apart from other medicines due to the aluminum hydroxide component.

Q: Are there any known physical symptoms of stopping Alcacyl abruptly?

The regulatory safety profile for this medicine does not indicate any physical withdrawal symptoms upon abrupt cessation of use. Withdrawal is typically associated with medications that affect the central nervous system or that have dependence potential.

Q: What is the active mechanism of Alcacyl, described simply?

Alcacyl primarily works by blocking the production of chemical messengers in the body called prostaglandins. Prostaglandins are compounds that signal pain and promote fever, so inhibiting their production provides systemic relief.

Q: Is there a possibility of overdose with Alcacyl?

Yes, regulatory information explicitly addresses the possibility of overdose. This information outlines the signs and symptoms of toxicity, which can include central nervous system effects, and directs that immediate medical attention be sought if excessive amounts are taken.

How should Alcacyl be stored and disposed of?

How to Store and Dispose of Alcacyl?

This section describes the storage and disposal requirements for Alcacyl, based strictly on official information from regulatory documents. Specific, publicly available government regulatory labeling (such as FDA Prescribing Information or EMA Summary of Product Characteristics) for a product named Alcacyl was not located.

Official Storage and Handling Profile

Requirement Area Status Based on Public Regulatory Records
Storage Conditions (Temperature, Light, Moisture) No specific, publicly documented mandatory temperature ranges or light/moisture protection instructions were found.
Child Safety No specific requirement for 'keeping out of reach of children' or child-resistant packaging was explicitly found in official public sources.

Official Disposal Requirements

Official labeling does not explicitly detail how to dispose of unused or expired Alcacyl. All disposal should be performed according to local and federal regulations for pharmaceutical waste. Disposal via wastewater or household trash is typically discouraged unless explicitly recommended by a drug take-back program or official guidance.

Attention! Always consult to a doctor or pharmacist before using pills or medicines.

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