Acton Prolongatum

Infantile spasm, bronchial asthma, rheumatoid arthritis, multiple sclerosis, myasthenia gravis, lupus erythematosus disseminatus, ulcerative colitis, chronic active liver disease, hay fever & severe dermatitis.

Long term treatment - 15-30IU (0.25-0.5ml) SC every 2 days for protracted treatment. If no effect, increase dose to 60IU (1ml) per day or every 2 days. Severe dermatological disorders: 60IU or more daily. Short term treatment: Daily doses upto 120IU (2ml) for intensive treatment (eg. multiple sclerosis, myasthenia gravis & ulcerative colitis). Infantile spasm: 20IU IM daily for 2 weeks. If no response, 30-40IU IM for additional 4 weeks.

Acton Prolongatum is contraindicated in patients with scleroderma, osteoporosis, systemic fungal infections, ocular herpes simplex, recent surgery, history of or the presence of a peptic ulcer, congestive heart failure, hypertension, or sensitivity to proteins of porcine origin.

Acton Prolongatum may accentuate the electrolyte loss associated with diuretic therapy.

Applies to Acton Prolongatum: injection gel/jelly

In addition to its needed effects, some unwanted effects may be caused by Acton Prolongatum (the active ingredient contained in Acton Prolongatum). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking Acton Prolongatum:

More common:

• Backache
• blurred vision
• body aches or pain
• chest pain
• cough
• difficulty with breathing
• dizziness
• ear congestion
• earache
• facial hair growth in females
• fever or chills
• fractures
• full or round face, neck, or trunk
• headache
• increased thirst or urination
• irritability
• loss of sexual desire or ability
• loss of voice
• menstrual irregularities
• muscle wasting
• nasal congestion
• nervousness
• pounding in the ears
• redness or swelling in the ear
• runny nose
• shortness of breath
• slow or fast heartbeat
• sneezing
• sore throat
• tightness in the chest
• troubled breathing
• unusual tiredness or weakness
• wheezing
• white patches in the mouth or throat or on the tongue
• white patches with diaper rash

• Convulsions (seizures)

• Accumulation of pus
• bruising
• bulging soft spot on the head of an infant
• change in the ability to see colors, especially blue or yellow
• cold, clammy skin
• confusion
• decreased range of motion
• decreased urine output
• dilated neck veins
• extreme fatigue
• eyeballs bulge out of eye sockets
• fast, weak pulse
• full or bloated feeling
• heartburn
• insomnia
• irregular breathing
• irregular heartbeat
• joint pain
• large, flat, blue, or purplish patches in the skin
• lightheadedness
• limp
• loss of appetite
• nausea and vomiting
• pressure in the stomach
• severe headache
• small red or purple spots on the skin
• sweating
• swelling of abdominal or stomach area
• swelling of the face, fingers, feet, or lower legs
• swollen, red, or tender area of infection
• trouble healing
• weight gain
• wheezing

• Bloating
• chills
• confusion
• constipation
• coughing up blood
• darkened urine
• fast heartbeat
• fever
• headache
• headache, sudden and severe
• increased sweating
• indigestion
• loss of appetite
• pain in the muscles
• pains in the stomach, side, or abdomen, possibly radiating to the back
• redness of the face
• skin rash
• unusual weight loss
• weakness
• yellow eyes or skin

• Decreased carbohydrate tolerance
• hypokalemic alkalosis
• reversible brain shrinkage

Minor Side Effects

Some of the side effects that can occur with Acton Prolongatum may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:

• Blemishes on the skin
• diarrhea
• pimples

• Increased or decreased appetite

• Increased hair growth, especially on the face
• menstrual changes
• muscle weakness

• Feeling of constant movement of self or surroundings
• sensation of spinning
• thinning of the skin

Acton Prolongatum (Acton Prolongatum or adrenocorticotropic hormone) is a polypeptide hormone produced and secreted by the pituitary gland. It is an important player in the hypothalamic-pituitary-adrenal axis.