Components:
Treatment option:
Medically reviewed by Kovalenko Svetlana Olegovna, PharmD. Last updated on 03.04.2022
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Treatment of diseases of the female genitals, accompanied by a violation of the normal microflora:
non-specific colpitis (as an independent remedy or after the end of the course of antibacterial therapy),
vaginal dysbiosis, including bacterial vaginosis (as an independent remedy or in complex therapy),
subacute and chronic stages of inflammatory processes of the female genital area (after the end of the course of antibacterial therapy for the purpose of rehabilitation),
hormone-dependent colpitis, including senile colpitis (as an independent remedy or against the background of specific hormone therapy),
preparation for planned gynecological operations to prevent postoperative infectious complications,
prenatal training of pregnant women at risk for the development of inflammatory diseases for the prevention and treatment of vaginal dysbiosis,
as an auxiliary agent in combination and after specific antimicrobial, antiviral and immunomodulatory therapy in the treatment of urogenital infections and sexually transmitted diseases (gonorrhea, urogenital chlamydia, urogenital herpes, etc.).
Intravaginal.
In the treatment of senile vaginitis of hormonal nature and vaginal dysbiosis - 1 supp. 2 times a day for 5-10 days. In case of violation of the purity of the vaginal secretions in pregnant women up to III-IV degree, the drug is used 1 supp. 1-2 times a day for 5-10 or more days until the purity of the vaginal secretions is restored to I-II degree and the clinical symptoms disappear.
For the prevention of purulent-septic complications apply 1 supp. 1-2 times a day for 5-10 days before the intended operation or delivery.
For the purpose of rehabilitation therapy after the use of antibiotics apply 1 supp. 1-2 times a day for 10 days. The course is repeated as prescribed by a doctor in 10-20 days.
Not installed. It is not recommended for vulvovaginal candidiasis.
Not installed.
Acylact has a high antagonistic activity against pathogenic and conditionally pathogenic microbes, including staphylococci, enteropathogenic escherichia coli, proteus, which determines the corrective effect of the drug in violations of the bacteriocenosis of the genitals in women.
- Other antimicrobial, antiparasitic and anthelmintic agents
At a temperature of 2-10 °C.
Keep out of reach of children.
The shelf life of the drug Atsilakt1 год.Do not use after the expiration date indicated on the package.
Instructions for medical useAtsilakt
Instructions for medical use-RU no. R N000283/01
Last modified date: 15.06.2017
Dosage form
Vaginal suppositories.
Composition
Composition per 1 suppository (1 dose).
Active Component:
- Atsilakt, substance-powder containing live cells of Lactobacillus acidophilus at least 107-3-8 %.
Components of the protective drying medium (sucrose-gelatin-milk):
- sucrose - 0.7 - 0.75 %,
- gelatin - 0.12 - 0.13 %
- skimmed milk (obrat) - 1,2-1,3 %.
Excipients:
- confectionery fat or imported solid fat - 75-80 %
- solid petroleum paraffin-5-10%
- emulsifier T-2 -5-10%.
Description of the dosage form
Suppositories from yellowish-gray to light beige color, cone-shaped or cylindrical shape with a specific smell of fat, color heterogeneity in the form of inclusions or "marbling", darkening of light brown color at the cone - shaped end of the suppository is allowed.
Pharmacotherapeutic group: eubiotic.
Characteristics
Acylact is a microbial mass of live antagonistically active lactobacilli of acidophilic strains of Lactobacillus acidophilus 100a, NK 1 To 3 Sh 24 , lyophilized in a culture medium with the addition of a protective (sucrose-gelatin-milk) drying medium, formed in a suppository.
Pharmacological (immuno-biological) properties
Acylact has a high antagonistic activity against pathogenic and opportunistic microbes, including Staphylococcus spp., Escherichia coli, Proteus spp., which determines the corrective effect of the drug in disorders of the vaginal microbiocenosis. In candidiasis, Acylact is not recommended, since in some cases, the pH of the vagina is shifted to the acidic side, which contributes to the growth of fungi.
Indications
- colpitis caused by opportunistic pathogens. It is prescribed as an independent remedy or after the end of the course of antibacterial therapy,
- vaginal dysbiosis, including bacterial vaginosis. It is prescribed as an independent remedy or in complex therapy,
- - senile colpitis of a hormonal nature. It is prescribed against the background of specific hormone therapy,
- subacute and chronic infectious diseases of the vagina. It is prescribed after the end of the course of antibacterial therapy for the purpose of rehabilitation,
- for the prevention of postoperative infectious complications in preparation for planned gynecological operations, in cases where antibiotic prophylaxis is not used, or after its completion, since antimicrobial chemotherapeutic agents will neutralize the effect of acidophilic lactobacilli,
- prenatal preparation of pregnant women at risk for the development of inflammatory diseases in order to prevent and treat vaginal dysbiosis,
- as an auxiliary agent in combination with specific antimicrobial, antiviral and immunomodulatory therapy in the treatment of urogenital infections and sexually transmitted diseases (gonorrhea, urogenital chlamydia, urogenital herpes, etc.).
It is possible to combine the use of suppositories and one of the oral forms of Acylact on the recommendation of a doctor.
Contraindications
Hypersensitivity to the components of the drug. It is not recommended for vulvovaginal candidiasis.
Use during pregnancy and lactation
Lactobacilli are representatives of the normal human microflora. Preparations made on their basis can be used during pregnancy and lactation.
Method of administration and dosage
Before intravaginal administration, the packaging material is removed from the suppository.
- In the treatment of colpitis caused by conditionally pathogenic microorganisms, Acylact is prescribed 1 suppository 2 times a day for 5-10 days.
- In the treatment of vaginal dysbiosis, including bacterial vaginosis, Acylact is prescribed 1 suppository 2 times a day for 5-10 days.
- In the treatment of senile colpitis of a hormonal nature, Acylact is prescribed 1 suppository 2 times a day for 5-10 days against the background of specific hormone therapy.
- In the treatment of subacute and chronic infectious diseases of the vagina, for the purpose of rehabilitation after the end of the course of antibacterial therapy, Acylact is used 1 suppository 1-2 times a day for 10 days. The course is repeated as prescribed by a doctor in 10-20 days.
- To prevent postoperative infectious complications in preparation for planned gynecological operations, Acylact is used 1 suppository 1-2 times a day for 5-10 days before the intended operation or delivery.
- During the prenatal preparation of pregnant women of the "Risk Group" in case of violation of the purity of the vaginal secretions to the III - IV degree, Acylact is used 1 suppository 1-2 times a day for 5 -10 or more days under the control of restoring the purity of the vaginal secretions to the I - II degree and the disappearance of clinical symptoms.
- As an auxiliary agent for the treatment of urogenital infections, Acylact is used for 1 suppository 1-2. times a day for 10 days.
Side effects
May cause allergic reactions.
Overdose
Not identified.
Interaction
The use of Acylact may be combined with the simultaneous administration of antimicrobial, antiviral and immunomodulatory therapy.
It is not recommended to combine with the simultaneous local administration of antibacterial drugs.
Special instructions
Special instructions.
Acylact does not affect the performance of activities that require special attention and quick reactions (driving vehicles, machinery, etc.).)
Unsuitable for the use of the drug:
- the integrity of the packaging of which is violated,'
- without marking,
- with altered physical properties (discoloration, appearance of rancid fat smell, deformity of the suppository),
- with an expired expiration date.
Release form
Vaginal suppositories. 5 suppositories in a cell contour package made of PVC film/PE or PVC, or EP-73S, or imported for suppository containers:
2 cell contour packages in a pack with Instructions for use.
Storage conditions
Storage conditions.
The drug is stored in accordance with SP 3.3.2.1248-03 at a temperature not exceeding 10 ° C out of the reach of children.
Transportation conditions.
The drug is transported in accordance with SP 3.3.2.1248-03 at a temperature not exceeding 10 ° C.
Expiration date
1 year.
Conditions of supply of pharmacies
Without a prescription.
Ацилакт - инструкция по медицинскому применению - РУ № Р N000411/01 от 2018-04-09
Ацилакт - инструкция по медицинскому применению - РУ № Р N000411/01 от 2006-03-10
Vaginal suppositories | 1 supp. |
live individuals of acidophilic lactobacilli | at least 107 |
suppository base: solid fat, paraffin, emulsifier |
in a contour cell pack of 5 pcs. , in a pack of cardboard 2 packs or in a contour cell pack of 10 pcs., in a pack of cardboard 1 pack.
Before intravaginal administration, the packaging material is removed from the suppository. It is recommended the combined use of suppositories and one of oral forms of atsilakt. The use of suppositories can be combined with the simultaneous administration of antimicrobial, antiviral and immunomodulatory therapy. However, it is not recommended to combine with the simultaneous local administration of antibacterial drugs.
G01AX14 Lactobacilli
- A54 Gonococcal infection
- A56 Other sexually transmitted chlamydia diseases
- A60 Anogenital herpes virus infection [herpes simplex]
- N73. 9 Inflammatory diseases of the female pelvic organs, unspecified
- N74. 3 Gonococcal inflammatory diseases of the female pelvic organs (A54. 2 )
- N74. 4 Inflammatory diseases of the female pelvic organs caused by chlamydia (A56. 1 )
- N76 Other inflammatory diseases of the vagina and vulva
- N89. 8 Other non-inflammatory diseases of the vagina
- N95. 2 Postmenopausal atrophic vaginitis
- Z100* CLASS XXII Surgical Practice
- Z34 Monitoring the course of normal pregnancy
- Z98. 8 Other specified post-surgical conditions
Suppositories are white, yellowish-gray or light beige, torpedo-shaped, cone-shaped or cylindrical in shape with a specific smell of confectionery fat, color heterogeneity in the form of inclusions or "marbling"is allowed.