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Acido-Git Maalox

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Acido-Git Maalox

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Treatment option:

Medically reviewed

Rosario Oropesa

Last updated on 22/12/2025

This page provides general, reference-level information compiled from official medical sources. It is not a substitute for professional medical advice, diagnosis, or treatment. For decisions about your health, please consult a qualified healthcare professional.

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Overview of Acido-Git Maalox

Property Description
Active Ingredient(s) Aluminium Hydroxide, Magnesium Hydroxide
Form(s) Oral Suspension, Chewable Tablets
Pharmacological Class Antacid (Aluminum and magnesium containing)
Common Use Symptomatic relief of Gastric Hyperacidity
Origin Inorganic mineral-based compound

What Type of Medicine is Acido-Git Maalox ?

Acido-Git Maalox is an over-the-counter (OTC) medicine and a widely recognized combination product that belongs to the antacid pharmacological class. This grouping is clinically recognized for providing effective relief from issues caused by excessive acid in the stomach (gastric hyperacidity). Its formulation is supported by pharmacological studies demonstrating the efficacy of aluminum and magnesium salts in acid neutralization. This medicine provides relief by quickly neutralizing stomach acid, serving a critical role in treating common episodes of acute acid indigestion.


Composition and Form: The Mineral-Based Antacid Combination

The active components of this formulation are two distinct inorganic mineral-based salts: Aluminium Hydroxide and Magnesium Hydroxide. The medicine is a defining example of this combination, often available alongside common counterparts such as Alamag. These two active ingredients are formulated for the oral route of administration and are supplied as a liquid oral suspension or in the form of chewable tablets, offering patient choice in administration. The product is defined as a combination because it intentionally includes both aluminium salts and magnesium salts. This precise co-formulation is crucial for mitigating the specific gastrointestinal effects that are often associated with the individual use of either of these minerals, thereby significantly improving patient tolerance during episodes of sour stomach.


How Does Acido-Git Maalox Provide Relief?

Relief is achieved through the fundamental chemical process of acid neutralization, a localized buffering action that occurs immediately upon contact with stomach contents. The basic mineral salts react directly with the highly acidic hydrochloric acid in the gastric fluid, converting it into harmless substances such as water and salts. The mechanism relies on a dual kinetic profile: Magnesium Hydroxide acts quickly to provide rapid-onset relief, while the Aluminium Hydroxide component offers a more sustained buffering effect, collectively managing the discomfort associated with heartburn and sour stomach.

Regulatory References

  1. MedlinePlus
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What side effects are possible with Acido-Git Maalox ?

Possible Side Effects and Safety Information

The safety profile of Acido-Git Maalox, a combination of Aluminium Hydroxide and Magnesium Hydroxide, is defined by effects classified within Gastrointestinal Disorders and systemic Metabolism and Nutrition Disorders, according to official regulatory documentation. The co-formulation is designed to manage the common and expected adverse reactions associated with the individual components.


Regulatory Classification of Adverse Reactions

The most frequently reported effects are concentrated in the gastrointestinal system and are typically classified as common in official labels:

  • Diarrhea: Primarily linked to the Magnesium Hydroxide component.
  • Constipation: Primarily linked to the Aluminium Hydroxide component.

Less frequently, or with chronic use, effects are classified in the Metabolism and Nutrition Disorders system, including hypophosphatemia (low phosphate levels) and hypermagnesemia (elevated blood magnesium).


Serious Safety Considerations and Limitations

Serious adverse reactions are typically associated with long-term or high-dose use. Chronic use of aluminum-containing antacids can lead to severe hypophosphatemia, and in rare cases, Aluminum Intoxication (neurotoxicity/encephalopathy).

Population-Specific Constraint: Regulatory authorities emphasize a critical safety constraint for patients with severe renal impairment (kidney disease). Since both active minerals are primarily cleared by the kidneys, impaired function increases the risk of systemic accumulation, leading to toxicity like hypermagnesemia. Use is generally restricted or contraindicated in this population.

Interaction-Related Safety: The product is officially documented to carry a high-level risk of reducing the absorption of many other concurrently administered oral medications by altering gastric pH, which is a key safety limitation when considering overall medication use.

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Overdose and Emergency Response

Overdose and When to Seek Help

The official regulatory documents specify distinct clinical manifestations and serious risks associated with an overdose of the Aluminium Hydroxide and Magnesium Hydroxide combination.

Documented Overdose Manifestations

Acute overdose commonly presents with gastrointestinal symptoms including abdominal pain, vomiting, and diarrhoea. In high-risk individuals, large doses may lead to or aggravate more severe complications such as intestinal obstruction or ileus, which is a regulatory concern for elderly patients.

When Urgent Medical Help is Required

You must seek immediate medical attention if any severe or adverse reaction occurs or if an overdose is suspected. Regulators mandate contacting a doctor or going to a hospital straight away if symptoms suggest blockage of the bowel (ileus). Urgent care is also required if the patient has a known renal function deficiency, as this condition significantly increases the risk of systemic toxicity, necessitating specific emergency procedures.

Serious and Population-Specific Risks

Prolonged use or high doses, particularly in individuals with existing renal impairment, carry the risk of systemic toxicity, including hypermagnesemia, hyperaluminemia, and hypophosphatemia. In cases of severe toxicity, management protocols specified in regulatory documents include rehydration, forced diuresis, and the administration of intravenous Calcium Gluconate. For patients with impaired renal function, procedures such as haemodialysis or peritoneal dialysis are necessary to eliminate the absorbed ions.

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Therapeutic Uses of Acido-Git Maalox

Acido-Git Maalox may be used to provide temporary relief from symptoms associated with excess stomach acid. This medication may assist in managing discomfort in the upper digestive tract, addressing symptoms that include heartburn, acid reflux, and stomach ache. It may also be used in cases of mild esophagitis.

This medication is sometimes used as part of a regimen to alleviate symptoms associated with clinical scenarios such as flare-ups of chronic gastritis, duodenal or gastric ulcers, and hiatal hernia. The goal of using this medication is to help reduce the discomfort and irritation associated with stomach acid.

Quick Fact: Relief for Stomach Acid Symptoms
Targeted Use: Relief from discomfort and irritation caused by excess stomach acid.
Common Symptoms: Heartburn, acid reflux, and stomach ache.
Associated Conditions: May be used for symptom management in mild esophagitis, gastritis, and peptic ulcer disease.
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Eligibility and Restrictions for Use

Population Eligibility: Who Can and Cannot Use Acido-Git Maalox?

The eligibility for using Acido-Git Maalox (Aluminium Hydroxide and Magnesium Hydroxide) is strictly defined by regulatory criteria, focusing on absolute contraindications and use restrictions based on age and health status.

Contraindications and Prohibited Use

Contraindications prohibit use for certain patient groups. These include individuals with severe renal impairment or kidney failure, patients with hypophosphatemia (abnormally low phosphate levels), and those who are severely debilitated. Use is also strictly prohibited for patients with a known hypersensitivity to the active ingredients and those with hereditary fructose intolerance.

Conditional and Restricted Use

Population Group Regulatory Status and Limitation
Pediatric (Under 14 years) Not recommended; use in infants under two years is associated with risk of phosphate depletion and hypermagnesemia.
Older Adults (Geriatric) Use is permitted but requires caution due to a higher risk of complications, such as intestinal obstruction.
Pregnancy Not recommended during the first trimester due to limited data. Compatible with breastfeeding due to limited maternal absorption.
Renal Impairment Contraindicated in severe form; prolonged use must be avoided in all other cases of kidney impairment.

Eligibility is permitted for adults who do not possess any of the listed contraindications or health restrictions.

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What should I know about interactions with other medicines?

Interactions with other medicines and products

The interaction profile for Acido-Git Maalox, which contains Aluminium Hydroxide and Magnesium Hydroxide, is primarily defined by its effects on the absorption of other orally administered medicines. The official regulatory documents state that the antacid components interfere with absorption through physicochemical binding and chelation, leading to a reduction in the systemic exposure ( AUC and C max) of numerous co-administered drugs.


Absorption Interference and Timing Rules

This effect necessitates a mandatory timing constraint for nearly all oral medications. Regulatory information requires that the antacid must be administered 2 hours before or 2 hours after other oral medicines to avoid clinically significant impairment of their absorption. Specific drugs noted to have reduced exposure include Tetracyclines, Fluoroquinolone antibiotics, Digoxin, Levothyroxine, and Iron Salts. The FDA label specifically documents a 31% decrease in C max for Febuxostat when co-administered.


Restrictions and Population-Specific Cautions

Regulatory documents impose specific restrictions based on potential toxicity. Due to the risk of Hypermagnesemia and Hyperaluminemia, co-administration with other Magnesium-containing preparations is warned against. Furthermore, the combination with Citrates (found in juices and some drug formulations) is formally advised to be avoided in patients with renal impairment as citrates enhance the absorption of aluminum, increasing systemic toxicity risk in this population. A pharmacodynamic interaction is also noted where urine alkalinization may increase the excretion of Salicylates.

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Mechanism of Action

How Acido-Git Maalox Works

Acido-Git Maalox functions as a combination of aluminum hydroxide [ Al( OH)3] and magnesium hydroxide [ Mg( OH)2], both classified as non-systemic bases. The mechanism of action is confined to the gastric lumen, involving an acid-base neutralization reaction with hydrochloric acid ( HCl).

Magnesium hydroxide acts as a rapidly-dissociating base that buffers hydrogen ions ( H^+), forming water and a magnesium salt, thereby elevating the pH of the stomach contents. This shift in pH modulates the concentration gradient of H^+ ions at the mucosal interface.

Aluminum hydroxide contributes to the neutralization reaction but also exhibits a secondary cascade by binding to dietary phosphate ions ( PO4^3-). This interaction results in the formation of insoluble aluminum phosphate [ AlPO4] within the gastrointestinal tract, modulating the intestinal absorption of phosphate. The systemic consequence of the combined action is the reduction of free gastric acid available for diffusion and exposure to the upper gastrointestinal epithelium.

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Dosage and Administration Information

Acido-Git Maalox is strictly intended for oral administration and is supplied in two official forms: an oral suspension and chewable tablets. The approved administration protocol establishes a precise dosing schedule for adults and adolescents aged 12 years and older. The standard single liquid dose is 10 mL to 20 mL (equivalent to 2 to 4 teaspoonfuls), with administration permitted up to four times a day.

Doses are generally recommended to be spaced throughout the day and are often taken between meals and at bedtime. For the liquid suspension, ensuring the product is shaken well before use and measured with an accurate dosing device are required steps for proper administration. The dosage schedule is subject to specific limits regarding the total duration of use. Specifically, the maximum daily dose must not be used continuously for a period exceeding two weeks unless specifically directed by a healthcare provider.

Furthermore, there are specific parameters for certain populations: use in children under 12 years of age requires professional consultation, and administration to patients with known kidney disease is strongly cautioned against due to the risk of mineral accumulation. These instructions define the standardized, short-term usage pattern.

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Recent Clinical Evidence

Research Evidence / Overview of Studies for Acido-Git Maalox


Evidence for Symptomatic Relief of Acute Heartburn and Indigestion

The primary evidence for this antacid combination focuses on its studied use for symptomatic relief. Research examined how symptoms change over time in conditions characterized by acute or disruptive episodes, such as heartburn and gastric hyperacidity. This field of study primarily consists of short-term Randomized Controlled Trials (RCTs) and is supported by comprehensive Systematic Reviews that analyze the established antacid class.

In these trials, research examined outcomes related to physical discomfort, monitoring changes in symptom intensity following administration of the medicine. Findings describe patterns observed in the studies where patient-reported outcomes describing perceived discomfort were measured during the observed time intervals. Regulatory reviews describe a consensus supporting the use of this drug class for the management of symptoms associated with excess stomach acid.


Evidence Base for Use in Duodenal Ulcer Symptom Management

The evidence base for this antacid combination in studies related to duodenal ulcers is derived from historical Controlled Clinical Trials and older Randomized Controlled Trials. Research examined outcomes related to ulcer healing in adult patients presenting with cycles of stability and flare-ups, specifically those with endoscopically confirmed Duodenal Ulcer.

Older controlled trials reported the measured rates of ulcer healing over defined time intervals, such as approximately four weeks. Additionally, studies monitored how symptoms were reported in the observed populations, and research described observed symptomatic patterns.


Research Focus on Special Populations

Research was conducted in certain patient groups where symptoms may vary in intensity. Specifically, the antacid combination was studied for use in women experiencing heartburn symptoms during pregnancy. Findings for this subgroup are important to understanding symptom patterns, but evidence is limited and heterogeneous, as data for certain groups remain insufficient.


Key Limitations and Areas for Future Research

The research base for this combination is focused on acute, short-term outcomes. Follow-up durations were limited, often extending only for one to two weeks, restricting insights into long-term outcomes and chronic symptom management. Comparative evidence exploring the outcomes of this antacid against modern, longer-acting acid-reducing medicines over intermediate periods is lacking, and the existing evidence highlights what is still uncertain regarding outcomes related to systemic or functional imbalance over extended periods.

Key Studies & References

  1. DailyMed Label: MAXIMUM STRENGTH ANTACID- aluminum hydroxide, magnesium hydroxide, simethicone liquid (Representative product monograph)
  2. Healing of Duodenal Ulcer with an Antacid Regimen (Key historical RCT showing antacid efficacy in ulcer healing)
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Frequently Asked Questions (FAQ)

Common questions about Acido-Git Maalox (FAQ)


Q: How quickly does Acido-Git Maalox start to work after taking it?

Official information describes this class of medicine as working by directly neutralizing acid on contact inside the stomach. Because of the quick acid-base reaction, the magnesium component is known to provide a rapid onset of acid-buffering relief.


Q: How long does the effect of Acido-Git Maalox usually last?

The combination of aluminum and magnesium salts is intended to offer a sustained buffering action in the stomach contents. This combined action helps to provide relief that continues for a defined period, though this timeframe is often short compared to other acid-reducing medicines.


Q: Is Acido-Git Maalox the same as just 'Maalox'?

The drug Acido-Git Maalox contains the active ingredients commonly found in many Maalox products, specifically Aluminum Hydroxide and Magnesium Hydroxide. 'Maalox' is a recognized brand name for products in this antacid class, but the exact formulation and strength may vary between products carrying similar names.


Q: What kind of stomach issues is Acido-Git Maalox usually taken for?

According to official documentation, the medicine is indicated for the relief of symptoms associated with acid indigestion and sour stomach. This includes relief from heartburn and general upset stomach caused by excess gastric acid.


Q: Is Acido-Git Maalox available over the counter?

Yes, official regulatory documents classify this medicine as a Human OTC Drug, meaning it is generally available to purchase Over-the-Counter without requiring a prescription.


Q: Is it normal to feel a chalky taste after taking Acido-Git Maalox?

While a specific 'chalky taste' is not listed as an adverse reaction, this product is a mineral-based formulation. It is common for such chewable tablets or suspensions to leave a distinctive, residue-like taste in the mouth immediately after they are taken.


Q: Is it okay to take Acido-Git Maalox if I'm taking vitamins or supplements?

Official information states that the antacid should be administered 2 hours before or 2 hours after taking nearly all other oral medicines, including most supplements, to reduce this potential interference. Official documentation notes the antacid can interfere with supplements like Iron Salts.


Q: Are there any specific foods or drinks to avoid when using Acido-Git Maalox?

Official warnings indicate that patients with renal impairment (kidney problems) should avoid co-administration with Citrates. Citrates are substances found in certain food, drinks, and drug formulations, and they can increase the absorption of aluminum, which is a safety constraint for this population.


Q: Is Acido-Git Maalox suitable for use during pregnancy?

Official regulatory information states that the medicine is not recommended during the first trimester of pregnancy due to limited available data. The use of this medicine during pregnancy is a decision that involves evaluating individual patient factors and should be discussed with a healthcare provider.


Q: Can Acido-Git Maalox be given to children?

Regulatory instructions advise that the use of this medicine in children under 12 years of age requires a professional consultation. Its use in infants under two years is associated with specific risks and is not recommended.


Q: Are there different forms of Acido-Git Maalox, like liquid or tablets?

Yes, according to official product information, the medicine is officially supplied in two forms: an oral suspension (liquid) and chewable tablets.


Q: Can people with high blood pressure use Acido-Git Maalox?

Official labeling contains the sodium content for the formulation in the 'Other Information' section. Patients with conditions, such as high blood pressure, that require sodium restriction should note the specific sodium content found on the product label.


Q: Why do some people experience gas after taking antacids like Acido-Git Maalox?

Gas and bloating are common symptoms associated with gastric hyperacidity. Some commercial formulations containing aluminum and magnesium hydroxide also include the anti-gas agent Simethicone, indicating that pressure and bloating (often referred to as gas) are among the symptoms this product is intended to relieve.


Q: Can Acido-Git Maalox be taken at the same time as pain relievers?

Regulatory requirements dictate that the antacid should be taken 2 hours before or 2 hours after nearly all other oral medicines, including most pain relievers. This timing constraint helps to prevent the antacid from interfering with the absorption of the other medicine.


Q: Does Acido-Git Maalox interact with alcohol?

Regulatory information highlights that the combination of antacids and certain pain relievers (Salicylates) with alcohol may increase the risk of gastric irritation and bleeding, which is a safety constraint to consider.


Q: Are there any known allergic reactions associated with Acido-Git Maalox?

Official product information states that use is strictly prohibited for patients with a known hypersensitivity to the active ingredients. While rare, allergic reactions, which could include symptoms like hives or swelling, are possible adverse events.


Q: Is it possible to take too much Acido-Git Maalox?

Yes. Official instructions state that the patient should not exceed the maximum daily dosage in a 24-hour period. High-dose or chronic use increases the risk of toxicity, such as Hypermagnesemia (too much magnesium) and Hypophosphatemia (too little phosphate) in the blood.


Q: How long does Acido-Git Maalox stay in the body?

The medicine's primary action is localized to the gastrointestinal tract. Regulatory documents emphasize that for patients with severe renal impairment (kidney disease), the body cannot clear the absorbed minerals effectively, increasing the risk of accumulation and toxicity over time.


Q: What are the key findings from clinical studies on Acido-Git Maalox?

Studies examined outcomes related to symptom relief for heartburn and gastric hyperacidity. Research described patterns where patient-reported outcomes of discomfort were measured following administration of the medicine, supporting its use for acute symptomatic relief.


Q: Is Acido-Git Maalox mainly for symptom relief or actual healing?

The medicine's primary studied use is for symptomatic relief of acute episodes of acid indigestion and heartburn. While older controlled trials examined its role in duodenal ulcer healing, its modern research focus is on managing symptoms associated with excess stomach acid.


Q: Can Acido-Git Maalox be used for indigestion caused by spicy food?

The medicine is indicated for relief of symptoms associated with acid indigestion and sour stomach. These are general terms that may cover discomfort resulting from common triggers, such as the consumption of spicy or rich foods.


Q: Does Acido-Git Maalox have any sugar or artificial sweeteners?

Patients with dietary restrictions should consult the specific product label, as official documentation for various formulations lists inactive ingredients, including sweeteners like saccharin sodium, sucrose, or glucose.


Q: Is Acido-Git Maalox known to affect iron absorption?

Yes, official documents explicitly list Iron Salts among the medications whose systemic exposure is reduced by the antacid. This is because the antacid components interfere with absorption through a process known as physicochemical binding.


Q: Can I crush or chew the Acido-Git Maalox tablets?

The product is supplied as an oral suspension and as chewable tablets. The official directions for the tablet form specify that they are designed to be chewed thoroughly before swallowing.


Q: Does Acido-Git Maalox have a generic version available?

Yes. The active ingredients, Aluminum Hydroxide and Magnesium Hydroxide, are available in a variety of generic and store-brand formulations which are widely marketed as antacids.

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How should Acido-Git Maalox be stored and disposed of?

Storage and Disposal Requirements

Official regulatory labeling dictates precise storage conditions for Acido-Git Maalox (Aluminum Hydroxide/Magnesium Hydroxide) to maintain its stability. The medicine must be stored at Controlled Room Temperature, defined as 20°C to 25°C (68°F to 77°F), and protected from excess heat and moisture. For the liquid suspension, it is mandatory to protect from freezing.

Containers must be kept tightly closed and stored in their original packaging. All forms of the product must be kept out of reach of children.

Disposal instructions advise discarding unused or expired product properly, often through designated medicine take-back programs. The medicine should not be flushed down the toilet or poured down a sink.

Attention! Always consult to a doctor or pharmacist before using pills or medicines.

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