Zest-M

Pernicious anaemia, peripheral neuritis especially diabetic and alcoholic polyneuritis, trigeminal neuritis, vomiting of pregnancy, vitamin B complex deficiency, anorexia, agranulocytosis, radiation sickness, coeliac and idiopathic, steatorrhoea which are usually accompanied by malabsorption of vitamin B 12 and during administration of broad-spectrum antibiotics.

Oral

Alcoholic neuropathy; Diabetic neuropathy

Adult: 100 mg 4 times daily.

do not use in the treatment of leber disease or tobaco intoxication.

Beri Beri, Wenicke-korsakoff syndrome. diabetic neuropathy.

none known

anaphylactic reactions rarely, severe cases can cause death, urine yellow colouration,peripheral neuropathy in case of prolonged useage, arrythmias,

Zest-M (rINN, or S-benzoylthiamine O-monophoshate) is a synthetic S-acyl derivative of thiamine (vitamine B1). After absorption, Zest-M can be dephosphorylated by cells bearing an ecto-alkaline phosphatase to the lipid-soluble S-benzoylthiamine. Zest-M should not be confused with allithiamine, a naturally occurring thiamine disulfide derivative with a distinct pharmacological profile.