Vitalux-S

A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, Vitamin C (Vitalux-S), functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C (Vitalux-S) is considered an antioxidant.

A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Vitamin E (Vitalux-S)&

Zinc (Vitalux-S) Capsule: Each capsule contains Zinc (Vitalux-S) sulphate monohydrate 54.93 mg, thiamine nitrate 10 mg, riboflavin 10 mg, pyridoxine hydrochloride 3 mg, vitamin B12 (coated) equivalent to cyanocobalamin 15 mcg, ascorbic acid 150 mg, folic acid 1 mg, nicotinamide 50 mg and calcium pantothenate 12.5 mg.

Zinc (Vitalux-S) Syrup: Each 5 mL contains Zinc (Vitalux-S) gluconate 34.9 mg, thiamine mononitrate 2.5 mg, riboflavin 2.5 mg, pyridoxine hydrochloride 1 mg, cyanocobalamin 3 mcg, ascorbic acid 50 mg, d-panthenol 12.5 mg and niacinamide 25 mg in a flavoured liquid glucose sorbitol syrup base.

Vit & mineral deficiencies during recovery, pregnancy, breastfeeding & elderly.

For systemic use of All Natural Source Juicy Orange Vitamin C (Vitalux-S): prevention and treatment of hypo- and avitaminosis of Vitamin C (Vitalux-S); providing increased need for Vitamin C (Vitalux-S) during growth, pregnancy, lactation, with heavy loads, fatigue and during recovery after prolonged severe illness; in winter with an increased risk of infectious diseases.

For intravaginal use: chronic or recurrent vaginitis (bacterial vaginosis, nonspecific vaginitis) caused by the anaerobic flora (due to changes in pH of the vagina) in order to normalize disturbed vaginal microflora.

Oral

Vitamin E (Vitalux-S) deficiency

Adult: 40-50 mg of d-α tocopherol daily.

Child: Neonate: 10 mg/kg once daily; 1 mth-18 yr: 2-10 mg/kg/day, up to 20 mg/kg.

Oral

Supplementation in cystic fibrosis

Adult: 100-200 mg daily of dl-α-tocoferil acetate or 67-135 mg daily of d-α-tocopherol.

Child: As α- tocopheryl acetate: 1 mth-1 yr 50 mg once daily; 1-12 yr 100 mg once daily; 12-18 yr 200 mg once daily. Dose to be adjusted as needed.

Oral

Abetalipoproteinaemia

Adult: 50-100 mg/kg daily of dl-α-tocoferil acetate or about 33-67 mg/kg daily of d-α-tocopherol.

Child: Neonate: 100 mg/kg once daily; 1 mth-18 yr: 50-100 mg/kg once daily.

Patients with deficiency of B-complex vitamins, Zinc (Vitalux-S) and Zinc (Vitalux-S) or where supplementation of these vitamins and Zinc (Vitalux-S) can be beneficial. Such patients and conditions include: Patients who are on prolonged antibiotic therapy; those who are suffering from infection, injuries, burns, fever, illness; patients with diarrhoea and GI disorders; patients who have undergone surgical operations; patients on diet restrictions eg, in diabetes, anorexia and alcoholism and in elderly persons; pregnant and lactating women due to increased nutritional needs.

Treating vitamin A deficiency. It may also be used for other conditions as determined by your doctor.

Beta-Carotene (Vitalux-S) is a precursor to vitamin A, a fat-soluble vitamin.

• Beta-Carotene (Vitalux-S) may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Beta-Carotene (Vitalux-S). Use a sunscreen or protective clothing if you must be outside for a prolonged period.
• Your skin may turn slightly yellow while you are taking Beta-Carotene (Vitalux-S). This is harmless and not a cause for concern.
• Do not take large doses of vitamins (megadoses or megavitamin therapy) while taking Beta-Carotene (Vitalux-S) unless directed by your doctor.
• PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Beta-Carotene (Vitalux-S) during pregnancy. If you are or will be breast feeding while you are using Beta-Carotene (Vitalux-S), check with your doctor or pharmacist to discuss the risks to your baby.

Ascorbic acid (Vitamin C (Vitalux-S)) occurs naturally in foods such as citrus fruit, tomatoes, potatoes, and leafy vegetables. Vitamin C (Vitalux-S) is important for bones and connective tissues, muscles, and blood vessels. Vitamin C (Vitalux-S) also helps the body absorb iron, which is needed for red blood cell production.

Ascorbic acid is used to treat and prevent Vitamin C (Vitalux-S) deficiency.

Ascorbic acid may also be used for purposes not listed in this medication guide.

Vitamin E (Vitalux-S) is an antioxidant that occurs naturally in foods such as nuts, seeds, and leafy green vegetables. Vitamin E (Vitalux-S) is a fat-soluble vitamin important for many processes in the body.

Vitamin E (Vitalux-S) is used to treat or prevent Vitamin E (Vitalux-S) deficiency. People with certain diseases may need extra Vitamin E (Vitalux-S).

Vitamin E (Vitalux-S) may also be used for purposes not listed in this medication guide.

Zinc (Vitalux-S) is a naturally occurring mineral. Zinc (Vitalux-S) is important for growth and for the development and health of body tissues.

Zinc (Vitalux-S) sulfate is used to treat and to prevent Zinc (Vitalux-S) deficiency.

Zinc (Vitalux-S) sulfate may also be used for purposes not listed in this medication guide.

1 caplet daily.

This medication administered orally, IM, IV, intravaginally.

For the prevention of deficiency conditions All Natural Source Juicy Orange Vitamin C (Vitalux-S) dose is 25-75 mg / day, for the treatment - 250 mg / day or more in divided doses.

For intravaginal used ascorbic acid drugs in appropriate dosage forms.

Usual Adult Dose for Vitamin E (Vitalux-S) Deficiency

Treatment: 60 to 75 units orally once daily.

Prevention: 30 units orally once daily.

Usual Adult Dose for Tardive Dyskinesia

600 to 1600 units orally per day.

Usual Adult Dose for Sickle Cell Anemia

450 units orally per day.

Usual Adult Dose for Alzheimer's Disease

1000 units orally twice daily.

Usual Adult Dose for Dietary Supplement

Oral liquid formulation (Vitamin E (Vitalux-S)): 200 units (10 mL) orally once daily.

Usual Pediatric Dose for Vitamin E (Vitalux-S) Deficiency

1 unit/kg/day orally of water-miscible Vitamin E (Vitalux-S).

Usual Pediatric Dose for Retinopathy Prophylaxis

Prevention of retinopathy of prematurity or Bronchopulmonary dysplasia (BPD) secondary to oxygen therapy: 15 to 30 units/kg/day to maintain plasma levels between 1.5 to 2 mcg/mL (may need as high as 100 units/kg/day). Note: AAP considers this use investigational and routine use is not recommended.

Usual Pediatric Dose for Cystic Fibrosis

100 to 400 units/day orally.

Usual Pediatric Dose for Dietary Supplement

Dosing: 1 unit Vitamin E (Vitalux-S) = 1 mg dl-alpha-tocopherol acetate.

Oral:

Adequate Intake (AI):

1 to less than 6 months: 4 units daily

6 to less than 12 months: 5 units daily

Recommended Daily Allowance (RDA):

1 to 3 years: 6 units daily

4 to 8 years: 7 units daily

9 to 13 years: 11 units daily

13 years and Older: 15 units daily

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Although no longer available in the U.S., Vitamin E (Vitalux-S) injectable administered intravenously to premature infants may result in a potentially fatal syndrome consisting of thrombocytopenia, hepatomegaly, splenomegaly, ascites, and renal, hepatic, and pulmonary dysfunction.

Oral administration of large doses (200 mg per day) of a hyperosmolar Vitamin E (Vitalux-S) preparation to low-birthweight infants has been associated with the development of necrotizing enterocolitis.

Dialysis

Data not available

Other Comments

The oral liquid formulation (Vitamin E (Vitalux-S) [R]) is intended to enhance absorption in patients with conditions associated with malabsorption (e.g., Crohn's disease, ulcerative colitis ) or for patients who have difficulty swallowing capsules.

The oral liquid formulation (Vitamin E (Vitalux-S) [R]) may be taken directly or mixed with water or other beverage. It must be shaken well prior to each use and refrigerated after opening.

Zinc (Vitalux-S) 1 mg/mL (Zinc (Vitalux-S) Chloride Injection, USP) contains 1 mg Zinc (Vitalux-S)/mL and is administered intravenously only after dilution. The additive should be diluted prior to administration in a volume of fluid not less than 100 mL. For the metabolically stable adult receiving TPN, the suggested intravenous dosage is 2.5 to 4 mg Zinc (Vitalux-S)/day (2.5 to 4 mL/day). An additional 2 mg Zinc (Vitalux-S)/day (2 mL/day) is suggested for acute catabolic states. For the stable adult with fluid loss from the small bowel, an additional 12.2 mg Zinc (Vitalux-S)/liter of small bowel fluid lost (12.2 mL/liter of small bowel fluid lost), or an additional 17.1 mg Zinc (Vitalux-S)/kg of stool or ileostomy output (17.1 mL/kg of stool or ileostomy output) is recommended. Frequent monitoring of Zinc (Vitalux-S) blood levels is suggested for patients receiving more than the usual maintenance dosage level of Zinc (Vitalux-S).

For full term infants and children up to 5 years of age, 100 mcg Zinc (Vitalux-S)/kg/day

(0.1 mL/kg/day) is recommended. For premature infants (birth weight less than 1500 g) up to 3 kg in body weight, 300 mcg Zinc (Vitalux-S)/kg/day (0.3 mL/kg/day) is suggested.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. See PRECAUTIONS.

How supplied

Zinc (Vitalux-S) 1 mg/mL (Zinc (Vitalux-S) Chloride Injection, USP) is supplied in 10 mL Plastic Vials (List No. 4090).

Store at 20 to 25°C (68 to 77°F).

HOSPIRA, INC., LAKE FOREST, IL 60045 USA. Revised: October, 2004

See also:
What is the most important information I should know about Vitamin C (Vitalux-S)?

AV-block II and III degree, sinoatrial block, SSS, bradycardia (HR < 40 bpm), hypotension (in case of myocardial infarction, systolic blood pressure less than 100 mm Hg), cardiogenic shock, congestive heart failure IIB-III stages, acute heart failure, Prinzmetal's angina, lactation, concomitant use of MAO inhibitors, hypersensitivity to atenolol.

See also:
What is the most important information I should know about Vitamin E (Vitalux-S)?

Hypersensitivity to Vitamin E (Vitalux-S) or any component of the formulation

See also:
What is the most important information I should know about Zinc (Vitalux-S)?

Hypersensitivity to any of the ingredients of Zinc (Vitalux-S).

Use Beta-Carotene (Vitalux-S) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Beta-Carotene (Vitalux-S) with food or milk.
• If you are unable to swallow a capsule, you may open it and mix the contents with orange juice or tomato juice. Drink the mixture immediately.
• Take Beta-Carotene (Vitalux-S) regularly to receive the most benefit from it. Taking Beta-Carotene (Vitalux-S) at the same time each day will help you remember to take it.
• If you miss a dose of Beta-Carotene (Vitalux-S), take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Beta-Carotene (Vitalux-S).

Ascorbic acid (Vitamin C (Vitalux-S)) is used to prevent or treat low levels of Vitamin C (Vitalux-S) in people who do not get enough of the vitamin from their diets. Most people who eat a normal diet do not need extra ascorbic acid. Low levels of Vitamin C (Vitalux-S) can result in a condition called scurvy. Scurvy may cause symptoms such as rash, muscle weakness, joint pain, tiredness, or tooth loss.

Vitamin C (Vitalux-S) plays an important role in the body. It is needed to maintain the health of skin, cartilage, teeth, bone, and blood vessels. It is also used to protect your body's cells from damage. It is known as an antioxidant.

OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.

This vitamin may also be used with other vitamins for a certain eye condition (macular degeneration).

How to use Vitamin C (Vitalux-S)

Take this vitamin by mouth with or without food, usually 1 to 2 times daily. Follow all directions on the product package, or take as directed by your doctor.

If you are taking the extended-release capsules, swallow them whole. Do not crush or chew extended-release capsules or tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing. Take this product with a full glass of water (8 ounces/240 milliliters) unless your doctor directs you otherwise.

If you are taking the wafers or chewable tablets, chew them thoroughly and then swallow. If you are taking the lozenges, place the lozenge in your mouth and allow it to slowly dissolve.

If you are taking the powder, mix it thoroughly in the proper amount of liquid and stir well. Drink all of the liquid right away. Do not prepare a supply for future use. If you are using the liquid form of this vitamin, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

Dosage is based on your medical condition and response to treatment.

Use this vitamin regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

If you think you may have a serious medical problem, seek immediate medical attention.

This supplement is used to prevent or treat a lack of Vitamin E (Vitalux-S) in the body. A low body level of Vitamin E (Vitalux-S) is rare. Most people who eat a normal diet do not need extra Vitamin E (Vitalux-S). However, Vitamin E (Vitalux-S) supplements are used in premature newborns and in people who have problems absorbing enough Vitamin E (Vitalux-S) from their diets. Vitamin E (Vitalux-S) is important in protecting your body's cells from damage. It is known as an antioxidant.

How to use Natural Vitamin E (Vitalux-S)

Take this product by mouth as directed. Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.

If you are using a liquid form of this product, carefully measure your dose using a medication-measuring device or spoon. Do not use a household spoon because you may not get the correct dose. If your liquid form is a suspension, shake the bottle well before each dose.

Dosage is based on your medical condition and response to treatment. Do not increase your dose or take it more often than recommended. Taking too much Vitamin E (Vitalux-S) may increase your risk of side effects.

High doses of Vitamin E (Vitalux-S) (400 units or more per day) may increase the chance of rare but very serious side effects. There is no proof that high doses of Vitamin E (Vitalux-S) help to prevent or treat heart disease. There is very little evidence that it helps prevent or treat Alzheimer's disease. In some people, taking these high doses may even be harmful. Talk to your doctor or pharmacist and discuss the risks and benefits before taking Vitamin E (Vitalux-S) supplements.

If your doctor prescribes this product for Vitamin E (Vitalux-S) deficiency, use it regularly to get the most benefit from it. To help you remember, take it at the same time each day. You should see improvement of symptoms such as numbness/tingling of the hands/feet and weakness. If your condition persists or worsens, or if you think you may have a serious medical problem, seek immediate medical attention.

Reduce levodopa effects; increase Fe absorption.

See also:
What other drugs will affect Vitamin C (Vitalux-S)?

In an application with barbiturates, primidone increases the excretion of ascorbic acid in the urine.

With the simultaneous use of oral contraceptives reduces the concentration of ascorbic acid in blood plasma.

In an application of All Natural Source Juicy Orange Vitamin C (Vitalux-S) with iron preparations ascorbic acid, due to its regenerative properties, transforms ferric iron in the bivalent, which improves its absorption.

Ascorbic acid in high doses can decrease urine pH that while the application reduces the tubular reabsorption of amphetamine and tricyclic antidepressants.

With the simultaneous use of aspirin reduces the absorption of ascorbic acid by about a third.

All Natural Source Juicy Orange Vitamin C (Vitalux-S) in an application with warfarin may decrease effects of warfarin.

With the simultaneous application of ascorbic acid increases the excretion of iron in patients receiving deferoxamine. In the application of ascorbic acid at a dose of 500 mg / day possibly left ventricular dysfunction.

In an application with tetracycline is increased excretion of ascorbic acid in the urine.

There is a described case of reducing the concentration of fluphenazine in plasma in patients treated with ascorbic acid 500 mg 2 times / day.

May increase the concentration of ethinyl estradiol in the blood plasma in its simultaneous application in the oral contraceptives.

See also:
What other drugs will affect Vitamin E (Vitalux-S)?

Agents with Antiplatelet Properties (e.g., P2Y12 inhibitors, NSAIDs, SSRIs, etc.): Vitamin E (Vitalux-S) (Systemic) may enhance the antiplatelet effect of Agents with Antiplatelet Properties. Monitor therapy

Anticoagulants: Vitamin E (Vitalux-S) (Systemic) may enhance the anticoagulant effect of Anticoagulants. Monitor therapy

CycloSPORINE (Systemic): Vitamin E (Vitalux-S) (Systemic) may decrease the serum concentration of CycloSPORINE (Systemic). Monitor therapy

Ibrutinib: Vitamin E (Vitalux-S) (Systemic) may enhance the antiplatelet effect of Ibrutinib. Monitor therapy

Orlistat: May decrease the serum concentration of Vitamins (Fat Soluble). Management: Administer oral fat soluble vitamins at least 2 hours before or after the administration of orlistat. Similar precautions do not apply to parenterally administered fat soluble vitamins. Consider therapy modification

Tipranavir: May enhance the adverse/toxic effect of Vitamin E (Vitalux-S) (Systemic). Management: Patients taking tipranavir oral solution are advised to avoid taking additional Vitamin E (Vitalux-S), beyond the amounts contained in a multivitamin product. This interaction does not apply to tipranavir capsules. Consider therapy modification

See also:
What other drugs will affect Zinc (Vitalux-S)?

Pyridoxine reduces the effects of levodopa (but this does not occur if a dopa decarboxylase is also given); decreases serum concentrations of phenobarbitone. Concurrent administration of drugs eg, isoniazid, penicillamine and oral contraceptives increase the requirement for pyridoxine.

Absorption of cyanocobalamin from the GIT may be reduced by neomycin, aminosalicylic acid, histamine H₂-receptor antagonists and colchicine. Serum concentrations may be decreased by concurrent administration of oral contraceptives. Many of these interactions are unlikely to be of clinical significance but should be taken into account when performing assays for blood concentrations.

Parenteral chloramphenicol may attenuate the effect of vitamin B12 in anaemia.

Folate deficiency states may be produced by a number of drugs including antiepileptics, oral contraceptives, antituberculous drugs, alcohol and folic acid antagonists eg, aminopterin, methotrexate, pyrimethamine, trimethoprim and sulphonamides; folic acid may decrease serum-phenytoin concentrations.

There may be an increased risk of myopathy or rhabdomyolysis when nicotinic acid is used concurrently with statins. Nicotinamide may increase the requirements for insulin or oral hypoglycaemics.

Ascorbic acid may increase the absorption of iron-deficiency states.

Ascorbic acid is often given in addition to desferrioxamine to patients with iron overload (thalassemia) to achieve better iron excretion. However, early on in treatment when there is excess tissue iron, there is some evidence that ascorbic acid may worsen the iron toxicity, particularly to the heart. Thus, ascorbic acid should not be given for the first month after starting desferrioxamine treatment.

The absorption of Zinc (Vitalux-S) may be reduced by iron supplements, penicillamine, phosphorus-containing preparations and tetracyclines. Zinc (Vitalux-S) supplements reduce the absorption of copper, ciprofloxacin, iron, norfloxacin, penicillamine and tetracyclines.

See also:
What are the possible side effects of Beta-Carotene (Vitalux-S)?

Beta-Carotene (Vitalux-S) is generally well tolerated with a very low risk of toxicity. In contrast with vitamin A (excess intake of which may cause liver damage or birth defects), it is virtually impossible to overdose with Beta-Carotene (Vitalux-S), as the body eliminates any of the latter substance which is surplus to requirements. No adverse effects have been reported in pregnant or lactating women taking up to 50,000IU/day, and intakes up to 1000mg/Kg body weight given to rats showed no long term toxic effects. Very high intake of Beta-Carotene (Vitalux-S) (more than 100,000IU/day) may cause areas of the skin to take on an orange tone, which is harmless. Patients with diabetes, renal or liver disease, or with hyperthyroidism should take Beta-Carotene (Vitalux-S) with caution.

See also:
What are the possible side effects of Vitamin C (Vitalux-S)?

Applies to ascorbic acid: oral capsule, oral capsule extended release, oral capsule liquid filled, oral granule, oral liquid, oral lozenge/troche, oral powder, oral powder for solution, oral powder for suspension, oral solution, oral syrup, oral tablet, oral tablet chewable, oral tablet extended release, oral wafer

As well as its needed effects, ascorbic acid (the active ingredient contained in Vitamin C (Vitalux-S)) may cause unwanted side effects that require medical attention.

Severity: Moderate

If any of the following side effects occur while taking ascorbic acid, check with your doctor or nurse as soon as possible:

Less common or rare: - with high doses

• Side or lower back pain

Minor Side Effects

Some ascorbic acid side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Less common or rare: - with high doses

• Diarrhea
• dizziness or faintness (with the injection only)
• flushing or redness of skin
• headache
• increase in urination (mild)
• nausea or vomiting
• stomach cramps

See also:
What are the possible side effects of Vitamin E (Vitalux-S)?

Applies to Vitamin E (Vitalux-S): oral capsule, oral capsule liquid filled, oral liquid, oral powder for solution, oral solution, oral tablet, oral tablet chewable

In addition to its needed effects, some unwanted effects may be caused by Vitamin E (Vitalux-S) (the active ingredient contained in Centrum Singles-Vitamin E (Vitalux-S)). In the event that any of these side effects do occur, they may require medical attention.

Severity: Moderate

If any of the following side effects occur while taking Vitamin E (Vitalux-S), check with your doctor or nurse as soon as possible:

With doses greater than 400 Units a day and long-term use

• Blurred vision
• diarrhea
• dizziness
• headache
• nausea or stomach cramps
• unusual tiredness or weakness

See also:
What are the possible side effects of Zinc (Vitalux-S)?

Applies to Zinc (Vitalux-S) sulfate: capsules, tablets

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur while taking Zinc (Vitalux-S) sulfate (the active ingredient contained in Zinc (Vitalux-S))

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe vomiting; unusual restlessness; very dry mouth, eyes, or skin.