Vilco

Topical/Cutaneous

As antiseptic and disinfectant

Adult: As soln: Cleansing of skin, mucous membrane and wounds: 0.01-0.1%. Irrigation of deep wounds: 0.005%. Irrigation of bladder and urethra: 0.005-0.02%. Retention lavage of the bladder: 0.0025-0.005%. Disinfection and storage of surgical instruments: 0.13%; may be used w/ Na nitrite to avoid corrosion. As preservative: 0.01%-0.02% (ophth preparation); 0.002-0.2% (nasal and otic preparation). As shampoo: Seborrhoeic dermatitis: 0.2-0.5%. As cream: Napkin rash and other dermatoses: 0.13%. As vaginal douche: 0.02-0.05%. Refer to product information for specific directions for use.

Supplemental Glycine (Vilco) may have antispastic activity. Very early findings suggest it may also have antipsychotic activity as well as antioxidant and anti-inflammatory activities.

for the treatment of mild to moderate infections caused by susceptible strains of the designated microorganisms in the conditions as listed below:

Adults (Filmtab Tablets and Granules for

Oral Suspension)

Pharyngitis/Tonsillitis due to Streptococcus pyogenes (The usual drug of choice in the treatment and prevention of streptococcal infections and the prophylaxis of rheumatic fever is penicillin administered by either the intramuscular or the oral route. Clarithromycin is generally effective in the eradication of S. pyogenes from the nasopharynx; however, data establishing the efficacy of clarithromycin in the subsequent prevention of rheumatic fever are not available at present).

Acute maxillary sinusitis due to Haemophilus influenzae, Moraxella catarrhalis, or Streptococcus pneumoniae.

Acute bacterial exacerbation of chronic bronchitis due to Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis, or Streptococcus pneumoniae.

Community-Acquired Pneumonia due to Haemophilus influenzae, Mycoplasma pneumoniae, Streptococcus pneumoniae, or Chlamydia pneumoniae (TWAR).

Uncomplicated skin and skin structure infections due to Staphylococcus aureus, or Streptococcus pyogenes (Abscesses usually require surgical drainage).

Disseminated mycobacterial infections due to Mycobacterium avium, or Mycobacterium intracellulare

(clarithromycin) Filmtab tablets in combination with amoxicillin and PREVACID (lansoprazole) or PRILOSEC (omeprazole) Delayed-Release Capsules, as triple therapy, are indicated for the treatment of patients with H. pylori infection and duodenal ulcer disease (active or five-year history of duodenal ulcer) to eradicate H. pylori.

Filmtab tablets in combination with PRILOSEC (omeprazole) capsules or TRITEC (ranitidine bismuth citrate) tablets are also indicated for the treatment of patients with an active duodenal ulcer associated with H. pylori infection. However, regimens which contain clarithromycin as the single antimicrobial agent are more likely to be associated with the development of clarithromycin resistance among patients who fail therapy. Clarithromycin-containing regimens should not be used in patients with known or suspected clarithromycin resistant isolates because the efficacy of treatment is reduced in this setting.

In patients who fail therapy, susceptibility testing should be done if possible. If resistance to clarithromycin is demonstrated, a non-clarithromycin-containing therapy is recommended. (For information on development of resistance see Microbiology section.) The eradication of H. pylori has been demonstrated to reduce the risk of duodenal ulcer recurrence.

Children (Filmtab Tablets and Granules for

Oral Suspension)

Pharyngitis/Tonsillitis due to Streptococcus pyogenes.

Community-Acquired Pneumonia due to Mycoplasma pneumoniae, Streptococcus pneumoniae, or Chlamydia pneumoniae (TWAR)

Acute maxillary sinusitis due to Haemophilus influenzae, Moraxella catarrhalis, or Streptococcus pneumoniae

Acute otitis media due to Haemophilus influenzae, Moraxella catarrhalis, or Streptococcus pneumoniae

NOTE: For information on otitis media, see Clinical Studies - Otitis Media.

Uncomplicated skin and skin structure infections due to Staphylococcus aureus, or Streptococcus pyogenes (Abscesses usually require surgical drainage.)

Disseminated mycobacterial infections due to Mycobacterium avium, or Mycobacterium intracellulare

Adults (Filmtab Tablets)

Filmtab (clarithromycin extended-release tablets) are indicated for the treatment of adults with mild to moderate infection caused by susceptible strains of the designated microorganisms in the conditions listed below:

Acute maxillary sinusitis due to Haemophilus influenzae, Moraxella catarrhalis, or Streptococcus pneumoniae

Acute bacterial exacerbation of chronic bronchitis due to Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis, or Streptococcus pneumoniae

Community-Acquired Pneumonia due to Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis, Streptococcus pneumoniae, Chlamydia pneumoniae (TWAR), or Mycoplasma pneumoniae

Treating cold sores and fever blisters. It may also be used for other conditions as determined by your doctor.

Benzalkonium Chloride (Vilco) is a topical antiseptic. It works by killing sensitive germs.

Acetaminophen is a pain reliever and fever reducer.

Chlorpheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Oxymetazoline (Vilco) (Acetaminophen, chlorpheniramine, and pseudoephedrine) is a combination medicine used to treat headache, fever, body aches, runny or stuffy nose, sneezing, itching, watery eyes, and sinus congestion caused by allergies, the common cold, or the flu.

Oxymetazoline (Vilco) may also be used for purposes not listed in this medication guide.

Topical/Cutaneous

As antiseptic and disinfectant

Adult: As soln: Cleansing of skin, mucous membrane and wounds: 0.01-0.1%. Irrigation of deep wounds: 0.005%. Irrigation of bladder and urethra: 0.005-0.02%. Retention lavage of the bladder: 0.0025-0.005%. Disinfection and storage of surgical instruments: 0.13%; may be used w/ Na nitrite to avoid corrosion. As preservative: 0.01%-0.02% (ophth preparation); 0.002-0.2% (nasal and otic preparation). As shampoo: Seborrhoeic dermatitis: 0.2-0.5%. As cream: Napkin rash and other dermatoses: 0.13%. As vaginal douche: 0.02-0.05%. Refer to product information for specific directions for use.

As required for irrigation.

1.5% Glycine (Vilco) Irrigation USP should be administered only by the appropriate transurethraI urologic instrumentation.

It has been reported that absorption is significantly increased if the container is higher than 60 cm (24") above the patient.

This drug product should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.

Adult & children >6 year Use Oxymetazoline (Vilco) 0.05%, 1-6 year Use Oxymetazoline (Vilco) 0.025%. Infant <1 year & neonate Use Oxymetazoline (Vilco) 0.01%. Instil 1-2 drops or spray 1-2 puffs into each nostril 2-3 times daily.

Duration of Treatment: Unless specifically prescribed by the physician, Oxymetazoline (Vilco) should be used only be used for short periods of time [Oxymetazoline (Vilco) nasal drops 0.025%, 0.05% and nasal spray 0.05% (up to 10 days) and nasal drops 0.01% (5-7 days)].

Administration: Intranasal.

0.01% Nasal Drops: To facilitate and ensure correct dosing, Oxymetazoline (Vilco) for infants is equipped with a metering pipette. The figures next to the graduation marks indicate the quantity of liquid drawn up in drops. If 1 drop is to be applied, for instance, the solution should be drawn up until the level of the liquid is at mark 1. This ensures that the precise quantity required is then instilled into the nose.

The Following Procedure Has Also Proven Efficient: Depending on the age of the infant, drip 1 or 2 drops of the 0.01% solution onto cotton wool to wipe out the nostrils. The action of Oxymetazoline (Vilco) sets in within a few min, but may take up to 20 min for an observed effect.

See also:
What is the most important information I should know about Benzalkonium Chloride (Vilco)?

Use in occlusive dressings, casts and anal or vaginal packs.

Glycine (Vilco) supplementation is contraindicated in those hypersensitive to any component of the preparation. It is also contraindicated in those who are anuric (some Glycine (Vilco) gets converted to ammonia).

See also:
What is the most important information I should know about Oxymetazoline (Vilco)?

Oxymetazoline (Vilco) should not be given to patients who are hypersensitive to erythromycin, sulfonamides, or any component of the formulation, who have hepatic dysfunction, and porphyria. It is containdicated in infants of less than 2 months of age.

Oxymetazoline (Vilco) can not be used concurrently with pimozide or cisapride.

Use Benzalkonium Chloride (Vilco) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Benzalkonium Chloride (Vilco) is for external use only. Do not get it in your eyes or nose.
• Wash the affected area with warm water and a washcloth to remove any cosmetics (eg, lipstick), lotions, ointments, or other lip preparations.
• Prepare Benzalkonium Chloride (Vilco) for use according to the directions on the label.
• Apply the medicine by rubbing the affected area firmly with the applicator tip. Be careful not to damage the skin. Throw the applicator away after use.
• Wash your hands immediately after using Benzalkonium Chloride (Vilco).
• Do not brush your teeth or drink soft drinks or fruit juices for at least 1 hour after you use Benzalkonium Chloride (Vilco).
• If your symptoms get better but return later, you may use another dose. Do not use more than 3 times per day.
• If you miss a dose of Benzalkonium Chloride (Vilco), use it as soon as you remember. Continue to use it as directed by your doctor or on the package label.

Ask your health care provider any questions you may have about how to use Benzalkonium Chloride (Vilco).

Use Oxymetazoline (Vilco) drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• If you wear contact lenses, remove them before using Oxymetazoline (Vilco) drops.
• To use Oxymetazoline (Vilco) drops, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye and continue to apply pressure for 1 to 2 minutes after using the medicine. Do not blink. Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them. To prevent germs from entering your medicine, do not touch the applicator tip to any surface, including your eye. Keep the container tightly closed.
• If you miss a dose of Oxymetazoline (Vilco) drops and are using it regularly, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Oxymetazoline (Vilco) drops.

Bladder irrigation, ear, eye, nose and throat irrigation, gingivitis, perodontal diseases, preoperative disinfection of unbroken skin, stomatitis, thrush, tonsillitis, urethral irrigation.

Glycine (Vilco) is possibly effective for treating schizophrenia and ischemic stroke; treating leg ulcers when used with other conventional medicines. It may also be used as an adjuvant therapy for memory enhancement, benign prostatic hypertrophy (BPH), liver protection, cancer prevention and others.

This medication is used for temporary relief of congestion in the nose caused by various conditions including the common cold, sinusitis, hay fever, and allergies. It works by narrowing the blood vessels in the nose area, reducing swelling and congestion.

OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.

This drug may also be used to relieve "plugged ears" and to reduce swelling in the nose before certain surgery or procedures.

How to use Oxymetazoline (Vilco) nasal

Use this medication in the nose as directed. Follow all directions on the product package, or use as directed by your doctor. If you are uncertain about any of the information, consult your doctor or pharmacist.

Gently blow your nose before using this drug. Use your finger to close the nostril on the side not receiving the medication. While keeping your head upright, place the spray tip into the open nostril. Spray the medication into the open nostril as you breathe in through your nose. Sniff hard a few times to be sure the medication reaches deep into the nose. Repeat these steps for the other nostril if needed.

Avoid spraying the medication into your eyes or onto the middle of the inside of your nose (nasal septum).

Rinse the spray tip with hot water or wipe with a clean tissue after each use. Make sure that water does not get inside the container. Replace cap after each use.

This medication provides only temporary relief. Do not use more often, use more sprays, or use longer than directed because doing so may increase the risk of side effects. Also, do not use this medication for more than 3 days or it may cause a condition called rebound congestion. Symptoms of rebound congestion include long-term redness and swelling inside the nose and increased runny nose. If this occurs, stop using this medication and consult your doctor or pharmacist.

Inform your doctor if your condition worsens or persists after 3 days.

See also:
What other drugs will affect Benzalkonium Chloride (Vilco)?

Increased risk of corneal toxicity when used as preservative in anaesthetic eye drops.

Data is temporarily not available

See also:
What other drugs will affect Oxymetazoline (Vilco)?

No interactions with tricyclic antidepressants (TCAs) or monoamine oxidase inhibitors (MAOIs) of the tranylcypromine type have been reported in the recommended dosage of Oxymetazoline (Vilco). Overdosage or swallowing of Oxymetazoline (Vilco) and use of TCAs or MAOIs simultaneously or immediately prior to administration of Oxymetazoline (Vilco) can lead to an increase in blood pressure.

See also:
What are the possible side effects of Benzalkonium Chloride (Vilco)?

Paralysis of respiratory muscle, Allergic contact dermatitis, Apprehension, Collapse, Coma, Convulsion, Cyanosis (bluish discoloration of the skin), Death, Shortness of breath, Muscle weakness, Restlessness, Vomiting

Adverse reactions may include fluid and electrolyte disorders such as acidosis, electrolyte loss, marked diuresis, urinary retention, edema and dehydration; cardiovascular/pulmonary disorders such as pulmonary congestion, hypotension, tachycardia, angina-like pain and thrombophlebitis; other possible reactions include visual disturbances, convulsions, nausea, vomiting, diarrhea, vertigo and urticaria.

Literature includes reports on hyponatremia, hyperammonemia, transient blindness, coma (immediate or delayed), and digitalis toxicity in digitalized patients.

If an adverse reaction occurs, discontinue the irrigant and reevaluate the clinical status of the patient.

See also:
What are the possible side effects of Oxymetazoline (Vilco)?

Applies to Oxymetazoline (Vilco) nasal: nasal solution, nasal spray

In addition to its needed effects, some unwanted effects may be caused by Oxymetazoline (Vilco) nasal (the active ingredient contained in Oxymetazoline (Vilco)). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking Oxymetazoline (Vilco) nasal:

• Blurred vision
• fast, irregular, or pounding heartbeat
• headache, dizziness, drowsiness, or lightheadedness
• high blood pressure
• increase in runny or stuffy nose
• nervousness
• trembling
• trouble in sleeping
• weakness

Minor Side Effects

Some of the side effects that can occur with Oxymetazoline (Vilco) nasal may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

• Burning, dryness, or stinging inside of nose
• sneezing

A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.

A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter. [PubChem]

Each mL of Oxymetazoline (Vilco) 0.05% nasal spray also contains phenylmercuric acetate and Oxymetazoline (Vilco) as preservatives and aminoacetic acid, sorbitol, hydrochloric acid and purified water as other inactive ingredients.