Components:
Medically reviewed by Oliinyk Elizabeth Ivanovna, PharmD. Last updated on 26.06.2023

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It is indicated for the treatment of intestinal parasitosis caused by the presence of acute or chronic intestinal amebiasis caused by Enterobius vermicularis (pinworm), Ascaris lumbricoides (worms), Trichuris trichiura (whipworm), Necator americanus, Ancylostoma duodenale (hookworm), Strongyloides stercoralis, Taenia solium, Taenia saginata (tapeworm) and Hymenolepis nana.
In patients living in endemic areas, regular treatment with Vermox-plus ® (3-4 times per year) can significantly reduce re-infection with a high level of clinical significance.
Amebicide, intraluminal parasite.
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For Mebendazole (Vermox-plus), the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to Mebendazole (Vermox-plus) or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Concomitant treatment with cimetidine may inhibit the metabolism of Mebendazole (Vermox-plus) in the liver, resulting in increased plasma concentrations, especially in prolonged treatments. Therefore, we recommend the determination of these concentrations to allow dose adjustments. Avoid concomitant use of metronidazole or Vermox-plus ® and alcohol.
Vermox-plus ® is generally well tolerated at the recommended dose. However, patients with high parasite load have expressed diarrhea or abdominal pain when treated with Vermox-plus ®.Post-marketing experience: Within each system, the adverse reactions are classified according to the report of frequency, using the following:
Very common (> 1 / 10).
Common (> 1 / 100, <1 / 10).
Uncommon (> 1 / 1, 000, <1 / 100).
Rare (> 1 / 10, 000, <1 / 1, 000).
Very rare (<1 / 10, 000) including isolated reports.
Lymphatic and blood:
Very rare: neutropenia (with prolonged use persistently higher dose than recommended).
Immune system:
Very rare: hypersensitivity reactions including anaphylactic and anaphylactoid reaction.
Nervous system:
Very rare: convulsions in children.
Gastrointestinal System:
Very rare: abdominal pain, diarrhea (these symptoms are also the result of intestinal infection by itself).
Hepatobiliary disorders:
Very rare: hepatitis and abnormal liver function tests (with longer use persistently higher dose than recommended).
Subcutaneous tissue and skin:
Very rare: toxic epidermal necrolysis, Stevens-Johnson syndrome, rash, angioedema, urticaria, rash.
Kidney and urinary system:
Very rare: Glomerulonephritis (with prolonged use persistently higher dose than recommended)
Has been associated with the use of Quinfamide (Vermox-plus) headache, nausea, bloating and abdominal pain.
Most of the time these effects have been mild and transient.