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Medically reviewed by Kovalenko Svetlana Olegovna, PharmD. Last updated on 28.03.2022
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Urispas 200mg® (Urispas 200mg HCl) is indicated for symptomatic relief of dysuria, urgency, nocturia, suprapubic pain, frequency and incontinence as may occur in cystitis, prostatitis, urethritis, urethrocystitis/urethrotrigonitis. Urispas 200mg® is not indicated for definitive treatment, but is compatible with drugs used for the treatment of urinary tract infections.
Urispas 200mg reduces muscle spasms of the bladder and urinary tract.
Urispas 200mg is used to treat bladder symptoms such as frequent or urgent urination, increased night-time urination, bladder pain, and incontinence (urine leakage). These bladder symptoms are often caused by overactive bladder, prostate enlargement, bladder infections, or irritation of the urethra.
Urispas 200mg will not treat a bacterial or fungal bladder infection. Infections must be treated with an antibiotic.
Urispas 200mg may also be used for other purposes not listed in this medication guide.
Usual Adult Dose for Urinary Incontinence
100 to 200 mg orally 3 to 4 times daily. As symptoms improve dose may be reduced.
Usual Adult Dose for Urinary Frequency
100 to 200 mg orally 3 to 4 times daily. As symptoms improve dose may be reduced.
Usual Adult Dose for Dysuria
100 to 200 mg orally 3 to 4 times daily. As symptoms improve dose may be reduced.
Usual Pediatric Dose for Urinary Incontinence
Greater than 12 years: 100 to 200 mg orally 3 to 4 times daily. As symptoms improve dose may be reduced.
Usual Pediatric Dose for Urinary Frequency
Greater than 12 years: 100 to 200 mg orally 3 to 4 times daily. As symptoms improve dose may be reduced.
Usual Pediatric Dose for Dysuria
Greater than 12 years: 100 to 200 mg orally 3 to 4 times daily. As symptoms improve dose may be reduced.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
The use of Urispas 200mg is contraindicated in patients with lower urinary or gastrointestinal (GI) obstructions. Such conditions may include pyloric or duodenal obstruction, or ileus, achalasia, GI hemorrhage, or urologic obstructions.
Urispas 200mg exerts weak anticholinergic effects and should be administered cautiously in patients with glaucoma.
Urispas 200mg may cause drowsiness and blurred vision.
The safety and efficacy in children below the age of 12 years have not been determined.
Dialysis
Data not available
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What is the most important information I should know about Urispas 200mg?
You should not use this medication if you are allergic to Urispas 200mg, or if you have untreated or uncontrolled narrow-angle glaucoma, a blockage in your digestive tract (stomach or intestines), or if you are unable to urinate.
Before using Urispas 200mg, tell your doctor if you have glaucoma or urinary problems.
Urispas 200mg can cause drowsiness or blurred vision. Be careful if you drive or do anything that requires you to be alert and able to see clearly.
There may be other medicines that can interact with Urispas 200mg. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.
Stop using this medication and call your doctor if you have serious side effects such as hot and dry skin, confusion, pounding heartbeats, fluttering in your chest, or if you stop urinating.
Use Urispas 200mg as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Urispas 200mg may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
- If you miss a dose of Urispas 200mg, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Urispas 200mg.
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.Urispas 200mg it belongs to a group of medicines which relieve and prevent muscle spasms. Urispas 200mg is used to treat bladder symptoms such as frequent or urgent urination, increased night-time urination, bladder pain, and incontinence (urine leakage). These bladder symptoms are often caused by overactive bladder, prostate enlargement, bladder infections or irritation of the urethra. It can also be used to relieve painful urination, excessive urination at night and the inability to control urine flow that occurs after surgery, cystoscopy or catheterisation.
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What other drugs will affect Urispas 200mg?
Acetylcholinesterase Inhibitors: May diminish the therapeutic effect of Anticholinergic Agents. Anticholinergic Agents may diminish the therapeutic effect of Acetylcholinesterase Inhibitors. Monitor therapy
Aclidinium: May enhance the anticholinergic effect of Anticholinergic Agents. Avoid combination
Amantadine: May enhance the anticholinergic effect of Anticholinergic Agents. Monitor therapy
Anticholinergic Agents: May enhance the adverse/toxic effect of other Anticholinergic Agents. Monitor therapy
Botulinum Toxin-Containing Products: May enhance the anticholinergic effect of Anticholinergic Agents. Monitor therapy
Cannabinoid-Containing Products: Anticholinergic Agents may enhance the tachycardic effect of Cannabinoid-Containing Products. Exceptions: Cannabidiol. Monitor therapy
Chloral Betaine: May enhance the adverse/toxic effect of Anticholinergic Agents. Monitor therapy
Cimetropium: Anticholinergic Agents may enhance the anticholinergic effect of Cimetropium. Avoid combination
CloZAPine: Anticholinergic Agents may enhance the constipating effect of CloZAPine. Management: Consider alternatives to this combination whenever possible. If combined, monitor closely for signs and symptoms of gastrointestinal hypomotility and consider prophylactic laxative treatment. Consider therapy modification
Eluxadoline: Anticholinergic Agents may enhance the constipating effect of Eluxadoline. Avoid combination
Gastrointestinal Agents (Prokinetic): Anticholinergic Agents may diminish the therapeutic effect of Gastrointestinal Agents (Prokinetic). Monitor therapy
Glucagon: Anticholinergic Agents may enhance the adverse/toxic effect of Glucagon. Specifically, the risk of gastrointestinal adverse effects may be increased. Monitor therapy
Glycopyrrolate (Oral Inhalation): Anticholinergic Agents may enhance the anticholinergic effect of Glycopyrrolate (Oral Inhalation). Avoid combination
Glycopyrronium (Topical): May enhance the anticholinergic effect of Anticholinergic Agents. Avoid combination
Ipratropium (Oral Inhalation): May enhance the anticholinergic effect of Anticholinergic Agents. Avoid combination
Itopride: Anticholinergic Agents may diminish the therapeutic effect of Itopride. Monitor therapy
Levosulpiride: Anticholinergic Agents may diminish the therapeutic effect of Levosulpiride. Avoid combination
Mianserin: May enhance the anticholinergic effect of Anticholinergic Agents. Monitor therapy
Mirabegron: Anticholinergic Agents may enhance the adverse/toxic effect of Mirabegron. Monitor therapy
Nitroglycerin: Anticholinergic Agents may decrease the absorption of Nitroglycerin. Specifically, anticholinergic agents may decrease the dissolution of sublingual nitroglycerin tablets, possibly impairing or slowing nitroglycerin absorption. Monitor therapy
Opioid Agonists: Anticholinergic Agents may enhance the adverse/toxic effect of Opioid Agonists. Specifically, the risk for constipation and urinary retention may be increased with this combination. Monitor therapy
Oxatomide: May enhance the anticholinergic effect of Anticholinergic Agents. Avoid combination
Potassium Chloride: Anticholinergic Agents may enhance the ulcerogenic effect of Potassium Chloride. Management: Patients on drugs with substantial anticholinergic effects should avoid using any solid oral dosage form of potassium chloride. Avoid combination
Potassium Citrate: Anticholinergic Agents may enhance the ulcerogenic effect of Potassium Citrate. Avoid combination
Pramlintide: May enhance the anticholinergic effect of Anticholinergic Agents. These effects are specific to the GI tract. Avoid combination
Ramosetron: Anticholinergic Agents may enhance the constipating effect of Ramosetron. Monitor therapy
Revefenacin: Anticholinergic Agents may enhance the anticholinergic effect of Revefenacin. Avoid combination
Secretin: Anticholinergic Agents may diminish the therapeutic effect of Secretin. Management: Avoid concomitant use of anticholinergic agents and secretin. Discontinue anticholinergic agents at least 5 half-lives prior to administration of secretin. Consider therapy modification
Thiazide and Thiazide-Like Diuretics: Anticholinergic Agents may increase the serum concentration of Thiazide and Thiazide-Like Diuretics. Monitor therapy
Tiotropium: Anticholinergic Agents may enhance the anticholinergic effect of Tiotropium. Avoid combination
Topiramate: Anticholinergic Agents may enhance the adverse/toxic effect of Topiramate. Monitor therapy
Umeclidinium: May enhance the anticholinergic effect of Anticholinergic Agents. Avoid combination
See also:
What are the possible side effects of Urispas 200mg?
Applies to Urispas 200mg: oral tablet
As well as its needed effects, Urispas 200mg (the active ingredient contained in Urispas 200mg) may cause unwanted side effects that require medical attention.
Severity: Moderate
If any of the following side effects occur while taking Urispas 200mg, check with your doctor or nurse as soon as possible:
Rare
- Confusion
- eye pain
- skin rash or hives
- sore throat and fever
- Clumsiness or unsteadiness
- dizziness (severe)
- drowsiness (severe)
- fever
- flushing or redness of face
- hallucinations (seeing, hearing, or feeling things that are not there)
- shortness of breath or troubled breathing
- unusual excitement, nervousness, restlessness, or irritability
Minor Side Effects
Some Urispas 200mg side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:
More common:
- Drowsiness
- dryness of mouth and throat
- Blurred vision
- constipation
- difficult urination
- difficulty concentrating
- dizziness
- fast heartbeat
- headache
- increased sensitivity of eyes to light
- increased sweating
- nausea or vomiting
- nervousness
- stomach pain
A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem]
However, we will provide data for each active ingredient