Unibrom

Unibrom is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool to optimize surgical outcomes.

Unibrom™ (Unibrom ophthalmic solution) 0.07% is indicated for the treatment of postoperative inflammation and reduction of ocular pain in patients who have undergone cataract surgery.

Unibrom (Unibrom) is a non-steroidal anti-inflammatory drug (NSAID).

Unibrom is used to treat swelling and pain caused by cataract surgery.

Unibrom may also be used for purposes not listed in this medication guide.

Recommended Dosing

For the treatment of postoperative inflammation in patients who have undergone cataract extraction, one drop of Unibrom (Unibrom ophthalmic solution) ophthalmic solution should be applied to the affected eye(s) once daily beginning 1 day prior to cataract surgery, continued on the day of surgery, and through the first 14 days of the postoperative period.

Use with Other

Topical Ophthalmic Medications

Unibrom (Unibrom ophthalmic solution) ophthalmic solution may be administered in conjunction with other topical ophthalmic medications such as alpha-agonists, beta-blockers, carbonic anhydrase inhibitors, cycloplegics, and mydriatics. Drops should be administered at least 5 minutes apart.

How supplied

Dosage Forms And Strengths

Topical ophthalmic solution

Unibrom (Unibrom ophthalmic solution) 0.09% is supplied in a white LDPE plastic squeeze bottle with a 15 mm LDPE white dropper-tip and 15 mm polypropylene gray cap as follows:

1.7 ml in 7.5 ml container (NDC 67425-999- 17)

Storage

Store at 155° - 255°C (595° - 77°F).

Manufactured for: ISTA Pharmaceuticals, Inc. Irvine, CA 92618. Manufactured By: Bausch & Lomb Incorporated Tampa, FL 33637. Under license from: Senju Pharmaceuticals Co., Ltd. Osaka, Japan 541-0046. Revised: 9/2010

See also:
What is the most important information I should know about Unibrom?

You should not use this medication if you are allergic to Unibrom.

Before using Unibrom ophthalmic, tell your doctor if you have asthma, diabetes, arthritis, dry eye syndrome, a bleeding disorder, if you have had more than one eye surgery recently, or if you have an allergy to sulfites, aspirin, or other non-steroidal anti-inflammatory drugs (NSAIDs).

The Unibrom brand of Unibrom ophthalmic is usually given as 1 drop in each affected eye once daily for 14 days, starting 1 day before your surgery. The Unibrom brand of Unibrom ophthalmic is usually given as 1 drop in each affected eye twice daily for 14 days, starting 24 hours after your surgery.

Follow your doctor's dosing instructions very carefully. Do not use this medication for more than the number of days your doctor has recommended. Using a steroid eye drop too long can increase your risk of serious side effects that may damage your vision.

Stop using Unibrom ophthalmic and call your doctor at once if you have any change in your vision, eye redness or bleeding, eye pain or swelling, severe eye discomfort, increased tears, increased sensitivity to light, feeling like something is in your eye, or slow healing after your eye surgery.

Do not use this medication while wearing contact lenses.

Use Unibrom as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• To use Unibrom, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Do not blink. Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
• To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including your eye. Keep the container tightly closed.
• If you will be using Unibrom to treat both eyes after surgery, do not use the same bottle for both eyes. Doing so may increase the risk of passing an infection from one eye to the other.
• Soft contact lenses may absorb a chemical in Unibrom. Remove contact lenses before you use Unibrom. Ask your doctor how to use your contact lenses while using Unibrom.
• If you are using another medicine that you put in your eye, use Unibrom at least 5 minutes before or after using the other medicine.
• If you miss a dose of Unibrom, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Unibrom.

Unibrom is used in adults after a cataract surgery to reduce eye pain and swelling (inflammation).

See also:
What other drugs will affect Unibrom?

This medication Displaces from its association with blood proteins other drugs; reduces the effectiveness of antihypertensive drugs. Compared to other NSAIDs and corticosteroids Unibrom increases the risk of ulcerogenic action. This drug increases the risk of hyperkalemia when combined with potassium-sparing potassium-based diuretics and other drugs; increases the concentration of phenytoin and lithium in the blood. Anticoagulants increase the risk of bleeding. Aspirin reduces the concentration of piroxicam in the blood up to 80% of the original.

See also:
What are the possible side effects of Unibrom?

Applies to Unibrom ophthalmic: ophthalmic solution

In addition to its needed effects, some unwanted effects may be caused by Unibrom ophthalmic (the active ingredient contained in Unibrom). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking Unibrom ophthalmic:

More common:

• Blurred vision
• change in color vision
• decreased vision or other changes in vision
• difficulty seeing at night
• eye pain
• red, sore eyes
• sensitivity to light
• tearing

Minor Side Effects

Some of the side effects that can occur with Unibrom ophthalmic may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:

• Abnormal sensation in the eye
• burning or stinging of the eye
• feeling of having something in the eye
• headache
• itching of the eyes