Components:
Medically reviewed by Militian Inessa Mesropovna, PharmD. Last updated on 16.04.2022
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Top 20 medicines with the same components:
Treatment of short-term insomnia; induction of preanesthetic sedation.
Hypersensitivity to barbiturates; history of addiction to sedative-hypnotic drugs; history of porphyria; severe liver impairment; respiratory disease with dyspnea; nephrosis.
Alcohol, CNS depressants
Depressant effects of these drugs may be enhanced.
Anticoagulants, beta-blockers, calcium channel blockers (eg, Verapamil), theophyllines
Activity of these drugs may be reduced.
Anticonvulsants
Serum concentrations of carbamazepine, valproic acid and succinimides may be reduced. Valproic acid may increase barbiturate serum levels.
Corticosteroids
Effectiveness may be reduced.
Estrogens, estrogen-containing oral contraceptives
Effectiveness may be reduced.
Cardiovascular
Bradycardia; hypotension; syncope.
CNS
Drowsiness; agitation; confusion; headache; hyperkinesia; ataxia; CNS depression; paradoxical excitement; nightmares; psychiatric disturbances; hallucinations; insomnia; dizziness.
GI
Nausea; vomiting; constipation.
Hematologic
Blood dyscrasias (agranulocytosis, thrombocytopenia).
Hepatic
Liver damage.
Respiratory
Hypoventilation; apnea; laryngospasm; bronchospasm.
Miscellaneous
Hypersensitivity reactions (eg, angioedema, rashes, exfoliative dermatitis); fever; injection site reactions (eg, local pain, thrombophlebitis).