Triderm

Cream : homogeneous, soft consistency, white or almost white, not containing visible particles.

Ointment: homogeneous translucent, from white to light yellow, soft consistency, not containing foreign inclusions.

Dermatoses complicated by infections caused by drug-sensitive pathogens, or if infections are suspected, such as:

simple and allergic dermatitis ;

atopic dermatitis (including.h. diffuse neurodermatitis) ;

limited neurodermatitis ;

eczema ;

dermatomycosis (dermatophytia, candidiasis, multi-colored lichen), especially when localized in the inguinal region and large skin folds ;

simple chronic lichen (limited neurodermatitis).

Outwardly.

The ointment or cream should be applied in a thin layer on the entire affected surface of the skin and the surrounding tissue 2 times a day (morning and night). To ensure the effectiveness of treatment, the drug must be used regularly. The duration of the therapy depends on the size and localization of the lesion, as well as the patient's reaction.

If clinical improvement has not occurred after 3-4 weeks of treatment, this may serve as a reason to clarify the diagnosis.

hypersensitivity to any of the components of the drug ;

skin tuberculosis;

skin manifestations of syphilis ;

chickenpox ;

simple herpes ;

skin post-excinal reactions ;

open wounds (for ointment for external use) ;

childhood up to 2 years.

With caution : pregnancy (especially in the I trimester); childhood (> 2 years); long-term treatment; use in large areas of the skin or in case of violation of the integrity of the skin; use of occlusion dressings (especially in children).

The use of the drug Triderm^® during pregnancy is possible only when the intended benefit for the mother exceeds the potential risk for the fetus. Pregnant women should not be used in large areas of the skin or for a long period of time.

It is not known whether the components of the drug with breast milk are distinguished. Therefore, when prescribing the drug Triderm^® during lactation, the issue of stopping breastfeeding should be resolved.

Very rarely when using the Triderm drug^® a sense of burning, erythema, exudation, impaired pigmentation and itching are noted.

encountered in the use of local SCS (especially occlusion dressings) : burning sensation, itching, dry skin, folliculitis, hypertrikhosis, acne, hypopigmentation, period dermatitis, allergic contact dermatitis, skin maceration, the development of secondary infection, skin atrophy, stria, sweating.

Gentamicin-conditioned : transient skin irritation (erite, itching), usually not requiring termination of treatment.

Shredded with clotrimazol : erythema, tingling sensation, the appearance of blisters, peeling, local swelling, itching, urticaria, skin irritation.

Symptoms : with prolonged use of local SCS in high doses, it is possible to suppress the function of adrenal glands with the development of secondary adrenal failure and symptoms of hypercorticism, including Kushing's syndrome.

An overdose of clotrimazole at its local use does not lead to any symptoms.

With a single overdose, gentamicin does not expect any symptoms. Long-term treatment with gentamicin in elevated doses can lead to an increase in insensitive flora.

Treatment: symptomatic. Acute symptoms of hypercorticism are usually reversible. If necessary, correct electrolyte imbalance. In the case of chronic SCS toxicity, a gradual abolition of the SCS is recommended.

Combined drug for outdoor use.

Maz and Triderm cream^® combine the anti-inflammatory, anti-usual, anti-allergic and anti-exudative effects of SCS of beta metamethasone with the antifungal activity of clotrimazole and the wide antibacterial effect of sulfate gentamicin.

Clotrimazole has an antifungal effect due to impaired synthesis of ergosterin, which is an integral part of the cell membrane of mushrooms. Active in relation Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, Microsporum canis, Candida albicans, Malassezia furfur (Pityrosporum orbiculare).

Gentamicin is an antibiotic of a wide range of actions from the group of aminoglycosides. It acts bactericidal and provides highly effective local treatment of primary and secondary bacterial skin infections. Active in relation to gram-negative bacteria : Pseudomonas aeruginosa, Enterobacter aerogenes, Escherichia coli, Proteus vulgaris, Klebsiella pneumoniae; gram-positive bacteria : Staphylococcus aureus (coagulasopositive, coagulazonetic and some strains producing penicillinase).

• Anti-inflammatory, antibacterial, antifungal agent [Glucocorticosteroids in combinations]

Any interaction of the Triderm drug^® with other drugs not registered.

Keep out of the reach of children.

outdoor cream 0.05% + 0.1% + 1% - 3 years.

ointment for external use 0.5 mg / g + 1 mg / g + 10 mg / g - 2 years.

Do not apply after the expiration date indicated on the package.

Outdoor cream, 0.05% + 0.1% + 1%. On 15 or 30 g of cream in a tube of aluminum, coated with epoxy varnish and stoned membrane and PE-screw cap. On 1 tube placed in a cardboard pack.

Ointment for external use, 0.5 mg / g + 1 mg / g + 10 mg / g. For 15 or 30 g of ointment in the tube of aluminum, processed with epoxy varnish and closed membrane. The tube is additionally closed by a screwing PE-cap with a membrane punch. On 1 tube placed in a cardboard pack.

Uncounter.

The drug Triderm^® not intended for use in ophthalmology.

The continued local use of antibiotics can sometimes lead to an increase in resistant microflora. In this case, as well as with the development of irritation, sensitization or superinfection against the background of treatment with the Triderm drug^® treatment should be discontinued and appropriate therapy should be prescribed. Cross-allergic reactions with aminoglycoside antibiotics were observed.

Any side effects encountered in the use of system SCS, including the oppression of the function of the crust of adrenal glands, can also be noted with the local use of SCS, especially in children.

System absorption of SCS or gentamicin for local use will be higher if treatment is carried out on large areas of the skin or when using occlusion dressings, especially with prolonged treatment or violation of the integrity of the skin. Gentamicin should be avoided for open wounds and damaged skin. Otherwise, side effects characteristic of gentamicin during its system application are possible. Appropriate precautions should be followed in such cases, especially in the treatment of children.

With prolonged use of the drug, its abolition is recommended to be carried out gradually.

Use in pediatrics

Cream. Children are prescribed the drug only for strict indications and under medical supervision, t.to. systemic side effects associated with the use of local corticosteroids can develop more often than in adult patients. Such side effects include: suppression of the function of the hypothalamo-hypophisar-obstrenal system; Kushing's syndrome; growth delay; deceleration of weight gain; increase in HF, manifested by swelling of relatives, headache, two-way edema of the optic nerve disc.

Ointment. Children are prescribed the drug only for strict indications and under medical supervision, t.to. the development of systemic side effects associated with beta metamethasone is possible. When using the Triderm drug^®, like many other drugs for local use based on SCS, on extensive surfaces and / or with occlusion dressing, it is possible to suppress the function of the hypothalamo-hypophysar-on-beam system, a decrease in the excretion of growth hormone, as well as an increase in HF can be observed.

Impact on the ability to drive vehicles and work with mechanisms. No effect of the Triderm drug was revealed^® on the ability to drive vehicles and work with mechanisms.

• B35 Dermatophytia
• B35.3 Mycosis of feet
• B35.6 Fake epidermophytia
• B36.0 Multi-colored lichen
• B37 Candidosis
• B49 Mycosis unspecified
• L20 Atopic dermatitis
• L20.8 Other atopic dermatitis
• L23 Allergic contact dermatitis
• L28.0 Simple chronic lichen
• L30.3 Infectious dermatitis
• L30.9 Unspecified dermatitis
• L98.9 Damage to the skin and subcutaneous tissue is unspecified