Components:

Dextromethorphan Hbr, Idoxuridine, Oxomemazine, Sodium Benzoate

Medically reviewed by Fedorchenko Olga Valeryevna, PharmD. Last updated on 26.06.2023

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Top 20 medicines with the same components:

Toxil

Name of the medicinal product

Toxil

Qualitative and quantitative composition

An analog of deoxyuridine that inhibits viral DNA synthesis. The drug is used as an antiviral agent. [PubChem]

Therapeutic indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.

Ophthalmic

Herpes simplex keratitis

Adult: As 0.1% soln: Instill 1 drop in the affected eye(s) every hr. Taper to every 2 hr or 4 times daily. Continue treatment for at least 7 days.

Topical/Cutaneous

Cutaneous herpes simplex and herpes zoster

Adult: As 5% preparation: Paint onto the lesions 4 times daily for 4 days.

Dosage (Posology) and method of administration

Ophthalmic

Herpes simplex keratitis

Adult: As 0.1% soln: Instill 1 drop in the affected eye(s) every hr. Taper to every 2 hr or 4 times daily. Continue treatment for at least 7 days.

Topical/Cutaneous

Cutaneous herpes simplex and herpes zoster

Adult: As 5% preparation: Paint onto the lesions 4 times daily for 4 days.

Contraindications

Patients at risk of developing resp failure. During an acute attack. Patients receiving MAOI or for 2 wk after discontinuing them. Persistent or chronic cough.

Special warnings and precautions for use

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Toxil is used to treat viral infections (keratitis) in the eye caused by herpes simplex.

Interaction with other medicinal products and other forms of interaction

Other medicines - Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary.

When you are using Toxil, it is especially important that your health care professional know if you are using the following: Eye product containing boric acid. Boric acid may interact with the Toxil preparation causing a gritty substance to form or may interact with the preservative in the Toxil preparation causing a toxic effect in the eye.

Undesirable effects

Acute ocular irritation including burning, corneal stippling, vascularization, and clouding has been reported. Following prolonged use of Toxil, ocular irritation characterized by follicular conjunctivitis, blepharitis with punctal swelling, bulbar conjunctival hyperemia, and corneal epithelial staining has also been reported. In either case, the drug should be discontinued.

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