Sanor

A water-soluble benzodiazepine derivative effective in the treatment of anxiety. It has also muscle relaxant and anticonvulsant actions. [PubChem]

Sanor dipotassium tablets, USP are indicated for the management of anxiety disorders or for the short-term relief of the symptoms of anxiety. Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic.

Sanor dipotassium tablets, USP are indicated as adjunctive therapy in the management of partial seizures.

The effectiveness of Sanor dipotassium tablets, USP in long-term management of anxiety, that is, more than 4 months, has not been assessed by systematic clinical studies. Long-term studies in epileptic patients, however, have shown continued therapeutic activity. The physician should reassess periodically the usefulness of the drug for the individual patient.

Sanor dipotassium tablets, USP are indicated for the symptomatic relief of acute alcohol withdrawal.

Sanor is used to relieve symptoms of anxiety and alcohol withdrawal. Sanor may also be used to treat partial seizures.

Sanor is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

Sanor is available only with your doctor's prescription.

For the symptomatic relief of anxiety

Sanor T-TAB tablets are administered orally in divided doses. The usual daily dose is 30 mg. The dose should be adjusted gradually within the range of 15 to 60 mg daily in accordance with the response of the patient. In elderly or debilitated patients it is advisable to initiate treatment at a daily dose of 7.5 to 15 mg.

Sanor tablets may also be administered in a single dose daily at bedtime; the recommended initial dose is 15 mg. After the initial dose, the response of the patient may require adjustment of subsequent dosage. Lower doses may be indicated in the elderly patient. Drowsiness may occur at the initiation of treatment and with dosage increment.

For the symptomatic relief of acute alcohol withdrawal:

The following dosage schedule is recommended:

Thereafter, gradually reduce the daily dose to 7.5 to 15 mg. Discontinue drug therapy as soon as patient's condition is stable.

The maximum recommended total daily dose is 90 mg. Avoid excessive reductions in the total amount of drug administered on successive days.

As an Adjunct to Antiepileptic Drugs

In order to minimize drowsiness, the recommended initial dosages and dosage increments should not be exceeded.

Adults

The maximum recommended initial dose in patients over 12 years old is 7.5 mg three times a day. Dosage should be increased by no more than 7.5 mg every week and should not exceed 90 mg/day.

Children (9-12 years)

The maximum recommended initial dose is 7.5 mg two times a day. Dosage should be increased by no more than 7.5 mg every week and should not exceed 60 mg/day.

How supplied

Sanor 3.75 mg scored T-TAB tablets are supplied as blue-colored tablets bearing the letters OV, the distinctive T shape and a two-digit designation, 31: Bottles of 100 (NDC 55292-301-01).

7.5 mg scored T-TAB tablets are supplied as peach-colored tablets bearing the letters OV, the distinctive T shape and a two-digit designation, 32: Bottles of 100 (NDC 55292-302-01).

15 mg scored T-TAB tablets are supplied as lavender-colored tablets bearing the letters OV, the distinctive T shape and a two-digit designation, 33: Bottles of 100 (NDC 55292-303-01).

Recommended storage: Protect from moisture. Keep bottle tightly closed. Store at 20-25°C (68-77°F). See USP controlled room temperature. Dispense in a USP tight, light-resistant container.

Manufactured by: AbbVie LTD, Barceloneta, PR 00617. For: Recordati Rare Diseases Inc., Lebanon, NJ 08833, U.S.A. Revised: February 2013.

See also:
What is the most important information I should know about Sanor?

Hypersensitivity to Sanor or any component of the formulation; acute narrow-angle glaucoma

Documentation of allergenic cross-reactivity for benzodiazepines is limited. However, because of similarities in chemical structure and/or pharmacologic actions, the possibility of cross-sensitivity cannot be ruled out with certainty.

Canadian labeling: Additional contraindications (not in US labeling): Myasthenia gravis.

Use Sanor as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Sanor by mouth with or without food.
• If you also take clozapine, do not take it within 2 hours before or after taking Sanor. These doses must be separated. Check with your doctor if you have questions.
• Do not suddenly stop taking Sanor. You may have an increased risk of serious side effects.
• If you miss a dose of Sanor and are using it regularly, take it as soon as possible. If you do not remember until later, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Sanor.

Use: Labeled Indications

Alcohol withdrawal: Symptomatic relief of acute alcohol withdrawal.

Anxiety disorders: Management of anxiety disorders and short-term relief of the symptoms of anxiety.

Partial seizures: Adjunct therapy in the management of partial seizures.

See also:
What other drugs will affect Sanor?

If Sanor is to be combined with other drugs acting on the central nervous system, careful consideration should be given to the pharmacology of the agents to be employed. Animal experience indicates that Sanor dipotassium prolongs the sleeping time after hexobarbital or after ethyl alcohol, increases the inhibitory effects of chlorpromazine, but does not exhibit monoamine oxidase inhibition. Clinical studies have shown increased sedation with concurrent hypnotic medications. The actions of the benzodiazepines may be potentiated by barbiturates, narcotics, phenothiazines, monoamine oxidase inhibitors or other antidepressants.

If Sanor tablets are used to treat anxiety associated with somatic disease states, careful attention must be paid to possible drug interaction with concomitant medication.

In bioavailability studies with normal subjects, the concurrent administration of antacids at therapeutic levels did not significantly influence the bioavailability of Sanor tablets.

See also:
What are the possible side effects of Sanor?

Applies to Sanor: oral capsule, oral tablet, oral tablet extended release

In addition to its needed effects, some unwanted effects may be caused by Sanor. In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking Sanor:

Less common:

• Bladder pain
• bloody or cloudy urine
• difficult, burning, or painful urination
• frequent urge to urinate
• lower back or side pain
• shakiness and unsteady walk
• slurred speech
• trembling or shaking of the hands or feet
• unsteadiness, trembling, or other problems with muscle control or coordination

If any of the following symptoms of overdose occur while taking Sanor, get emergency help immediately:

Symptoms of overdose:

• Change in consciousness
• drowsiness
• loss of consciousness
• relaxed and calm
• sleepiness

Minor Side Effects

Some of the side effects that can occur with Sanor may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common:

• Blurred vision
• diarrhea
• discouragement
• dizziness
• double vision
• dry mouth
• feeling sad or empty
• headache
• indigestion
• irritability
• loss of appetite
• loss of interest or pleasure
• mental confusion
• nausea or vomiting
• nervousness
• passing of gas
• seeing double
• skin rash
• sleeplessness
• stomach pain, fullness, or discomfort
• trouble with concentrating
• trouble with sleeping
• unable to sleep
• unusual tiredness or weakness