Гемороль

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Гемороль

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Medically reviewed

Marina Burgos

Last updated on 10/01/2026

This page provides general, reference-level information compiled from official medical sources. It is not a substitute for professional medical advice, diagnosis, or treatment. For decisions about your health, please consult a qualified healthcare professional.

Overview of Гемороль

Quick Facts

Property Description
Active Ingredient Bensocaine (Synthetic) and a Phytocomplex (Natural Extracts)
Form Rectal Suppository
Pharmacological Class Analgesic, Antispasmodic, Astringent, Anti-inflammatory
General Purpose Symptomatic relief of local discomfort (pain, burning, irritation)
Origin Herbal-Synthetic Combination Drug

What Type of Medicine is Гемороль?

Гемороль (Hemorol) is formally defined as a specialized Herbal-Synthetic Combination Drug prepared as a Rectal Suppository, designed exclusively for local application. This medicine is classified under a multifaceted pharmacological group, exhibiting combined Analgesic, Antispasmodic, Astringent, and Anti-inflammatory effects. The suppository form is integral, as it is recognized for ensuring the active substances are concentrated and released directly onto the affected local tissue, maximizing local effect and providing relief in typical use scenarios involving anorectal irritation.


Composition: The Combination of Synthetic and Natural Components

This product is a multi-component combination product characterized by the unique integration of a single synthetic compound with a complex phytocomplex of six distinct natural plant extracts. The core synthetic ingredient is Bensocaine, which belongs to the class of local anesthetics and works by inhibiting nerve signal transmission to relieve pain. This is combined with the herbal component, which includes extracts such as Belladonnae Radicis Extractum Spissum and Matricariae Extractum Spissum. The inclusion of components like Matricariae flos (chamomile flower) supports treatments involving irritation of the mucosae in the anal region. This blend of rapid chemical numbing and traditional supportive actions is a distinguishing feature of Гемороль.


General Purpose: Symptomatic Relief and Local Comfort

The overall function of Гемороль is to provide effective, localized symptomatic relief and enhance patient comfort. The combined action of ingredients achieves this by addressing multiple discomforts simultaneously: Bensocaine relieves acute pain and burning, while the extracts contribute to reducing minor swelling and general irritation through anti-inflammatory and astringent properties. The general benefit is focused on quickly alleviating common anorectal symptoms, thus improving local well-being.

What side effects are possible with Гемороль?

Possible Side Effects and Safety Information

The safety profile for Гемороль, a combined local anesthetic and phytocomplex preparation, is based on the official adverse reactions documented for its components. Regulatory classifications identify reactions primarily as localized effects and potential systemic effects from the Bensocaine and Belladonna alkaloid content.

Category Regulatory Classification Description from Official Documents
Common Local reactions Burning, itching (pruritus), or redness (erythema) at the application site. Dryness of the mouth is associated with anticholinergic effects.
Rare Serious Reactions Methemoglobinemia is a rare but serious risk associated with Bensocaine, potentially reducing blood oxygen capacity. Severe systemic hypersensitivity and signs of systemic anticholinergic toxicity (e.g., severe confusion, urinary retention) are also documented concerns.

The officially documented adverse reactions are grouped by System-Organ Class including Skin and Subcutaneous Tissue Disorders (local irritation), Nervous System Disorders (dizziness, blurred vision), and Blood and Lymphatic System Disorders (Methemoglobinemia).

Safety Considerations and Restrictions

Official labels define constraints based on age and pre-existing conditions. The preparation is not recommended for pediatric use due to a documented increased risk of systemic effects, including Methemoglobinemia. Older adults may exhibit increased sensitivity to the anticholinergic effects of Belladonna alkaloids, raising the risk for conditions like confusion and urinary retention. Use during pregnancy and lactation is generally advised against due to a lack of adequate safety data.

The medicine is formally contraindicated in patients with a known hypersensitivity to any of its components. Due to the action of the phytocomplex, caution is advised or use is limited in patients with conditions such as glaucoma, prostatic hypertrophy, or certain types of tachyarrhythmia.

Overdose and Emergency Response

️ Overdose and when to seek help

The official regulatory profile for Гемороль overdose focuses on potential systemic toxicity from its active ingredients, Bensocaine and Belladonnae Extract.

Documented Manifestations Overdose exposure may present with signs of Methemoglobinemia, including pale, gray, or blue-colored skin, lips, or nail beds (cyanosis), accompanied by shortness of breath, headache, and a rapid heart rate. Systemic effects from the Belladonnae component can manifest as the Anticholinergic Toxidrome, involving confusion, agitation, delirium, dilated pupils, and urinary retention.

Severe Outcomes and Required Action Methemoglobinemia is a serious, potentially life-threatening outcome due to reduced oxygen capacity. Severe anticholinergic toxicity may progress to seizures or coma.

Regulators mandate that users seek medical attention immediately upon observing signs such as cyanosis or shortness of breath. The official instruction is to contact a Poison Control Center right away in case of suspected overdose.

Emergency Management Notes Management is generally based on symptomatic and supportive treatment. Specific documented interventions include the use of Methylene Blue for Methemoglobinemia and Physostigmine for reversing severe central anticholinergic syndrome. Continuous cardiac monitoring and assessment of oxygen levels are required during management. Infants and children younger than 2 years are specifically noted in regulatory documents as an increased risk population for Methemoglobinemia.

Therapeutic Uses of Гемороль

What Гемороль Treats: Main Uses and Benefits

The primary therapeutic role of Гемороль is to provide localized symptomatic relief for conditions affecting the anorectal area, focusing on key symptom clusters that create noticeable physiological strain. The medication is commonly used across conditions characterized by periods of heightened symptoms of hemorrhoids or localized anal irritation. The inclusion of a local anesthetic and other components is utilized for easing pain and burning associated with hemorrhoids and anorectal disorders.

The key indications for which the medicine is applied include symptomatic management of hemorrhoidal disease, anal fissures (cracks), and persistent rectal mucosal irritation.

Relief for Key Symptom Domains

The multi-component formulation is used to address groups of symptoms that may appear suddenly or intensify over time, providing support that helps ease the overall symptom load. The preparation is considered relevant when symptoms interfere with daily comfort. The preparation is used to help address acute manifestations, as summarized by the core intent:

“The preparation is considered relevant when supportive symptom management is appropriate for symptoms of increased discomfort or tension.”

The medication is specifically applied in addressing sharp local pain, intense burning sensations, involuntary muscular spasm, and symptoms related to inflammatory or irritative states such as minor swelling and persistent itching. This relief contributes to improved comfort during periods of heightened symptoms and assists with maintaining functional stability.


Quick Fact: Relief for Acute Discomfort

Symptom Axis Primary Benefit Use Context
Pain and Burning Ease of Pain/Burning Acute Flare-ups
Swelling and Irritation Support for Irritation Inflammatory States
Spasm and Tension Support for Tension/Spasm Discomfort after Bowel Movement

Regulatory References

  1. relevant for easing pain and burning associated with hemorrhoids and anorectal disorders

Eligibility and Restrictions for Use

Who Can and Cannot Use Гемороль?

The official population eligibility for Гемороль (Hemorol) is strictly defined by regulatory documents, which establishes the adult population as the standard user group. Eligibility is limited by explicit exclusions pertaining to age, hypersensitivity, and reproductive status.


Official Regulatory Exclusions

Category Regulatory Status and Official Wording
Populations for Whom Use is Contraindicated Pregnant Women (Explicitly prohibited from use.)
Patients with Hypersensitivity (Contraindicated if allergic to the active substances or any excipients.)
Populations for Whom Use is Not Recommended Children (Not recommended due to a lack of safety data.)
Lactation/Breastfeeding Women (Not recommended as safety has not been investigated.)

Eligibility Summary

The product is available for use by adults for approved indications. Regulatory classification dictates that pregnant women must not use the product. Additionally, use is not recommended for children and breastfeeding women because official regulatory safety investigation has not been established in these special populations. No specific restrictions are typically listed regarding renal or hepatic impairment in the standard labeling for this product.

What should I know about interactions with other medicines?

Interactions with other medicines and products

The official regulatory profile for Гемороль (Bensocaine and Phytocomplex rectal suppository) focuses primarily on pharmacodynamic interactions due to the additive effects of its active components, rather than changes in systemic exposure.

Documented Pharmacodynamic Interactions

Interaction Type Interacting Categories
Additive Anticholinergic Effects Other Anticholinergic Agents (e.g., certain antihistamines, tricyclic antidepressants)
Increased Risk of Methemoglobinemia Methemoglobinemia-Inducing Agents (e.g., dapsone, nitrates)
Additive CNS Depressant Effects Other Central Nervous System (CNS) Depressants

Co-administration with other anticholinergic agents may lead to reinforcement of systemic anticholinergic effects due to the tropane alkaloid content of the Belladonna extract component. Use with agents known to induce methemoglobinemia increases this hematologic risk, which is specifically attributable to the Bensocaine component. Use with CNS depressants may result in additive CNS depression.

Substance-Related Restrictions

The regulatory documents formally state a restriction on co-administration with Alcohol. Alcohol may intensify both the CNS depressant and anticholinergic-related symptoms associated with the product.

No significant pharmacokinetic interactions (e.g., CYP enzyme inhibition/induction), transporter-based interactions, or mandatory time-based separation rules are officially documented in the prescribing information for this local-acting medicine.

Mechanism of Action

Mechanism of Action (MoA)

The molecular action of Гемороль initiates through the interaction of its active constituents with alpha-adrenergic receptors located on the smooth muscle of the arteriolar walls. This ligand-receptor binding triggers a cascade that increases intracellular calcium ion ( Ca^2+) concentration.

The resulting activation of the Ca^2+-dependent contractile apparatus leads to localized vasoconstriction, primarily affecting the microvasculature. Concurrently, components modulate the cyclooxygenase (COX) and lipoxygenase (LOX) pathways, inhibiting the synthesis of inflammatory mediators, specifically prostaglandins and leukotrienes.

The combined actions of alpha-adrenergic stimulation and inflammatory mediator inhibition act synergistically to stabilize the endothelial barrier function and restrict fluid extravasation into the surrounding perivascular space. This modulation directly affects interstitial fluid dynamics within the targeted tissue.

Dosage and Administration Information

Administration Scope

Feature Guideline
Route of administration: Rectal.
Dosing schedule: The standard regimen is one suppository. For heightened discomfort, the regimen allows for up to two to three suppositories per day.
Frequency and Timing: Standard administration is once daily, typically performed at night. If the intensified two to three suppositories per day schedule is required, the doses are to be administered in a divided schedule.
Preparation requirements: The suppository must be freed from its foil packaging prior to insertion. Administration is generally recommended after the local area has been cleansed and dried.

Use Context and Duration

Feature Guideline
Course Duration / Cycle: Use is restricted to short-term courses, not to exceed seven consecutive days. The application should cease when the specific pain-related complaints have subsided.
Age-Group Administration Rules: Use is not recommended for children (pediatric patients under 18 years) due to the absence of sufficient safety and clinical experience data.
Maximum Dose Constraint: The maximum allowed daily intake must not exceed three suppositories within a 24-hour period.

Connection to the overall use protocol: The use of Гемороль is structured as a standardized, localized application for a limited time frame. These guidelines define the required rectal route, the specific daily dose range (one to three suppositories), and the seven-day maximum duration to guide the proper application of the medicine.

Recent Clinical Evidence

️ Evidence for Symptomatic Management of Anorectal Discomfort

Research exploring the class of topical combination preparations that includes components found in Гемороль was conducted during periods of increased symptom activity. The evidence often draws from short-term Randomized Controlled Trials (RCTs) and observational studies that have explored the relationship between use and changes in symptoms. Studies focused on adult patients with acute and uncomplicated hemorrhoidal symptoms (typically Grade I or II), or those with anal fissures and mucosal irritation.

Researchers examined patient-reported outcomes describing perceived discomfort, including measurements of changes in anal pain, burning, and muscular spasm/tension. Studies report how symptoms evolved in the observed populations during the defined time intervals, primarily over a few days to a few weeks. However, evidence quality varies across studies, and many reported outcomes were short-term.


⏳ Long-Term Research and Evidence Gaps

Research has explored outcomes for these topical preparations primarily in short-term scenarios. Follow-up durations were limited, typically measuring relief for up to 30 days. Long-term effects are not fully established for this product class, and there is limited information for long-term outcomes or continued symptomatic stability after the acute treatment period ends.

Data for certain groups, such as older adults, children, or those with multiple co-existing conditions, remain insufficient. The evidence for this specific multi-component product appears to be heterogeneous. This is because the evidence for its specific use is sometimes extrapolated from the well-documented performance of its individual active components. Evidence is limited by short follow-up durations and the variable evidence quality across studies.

Key Studies & References Labeling Standard for Anorectal Drugs (Non-prescription monograph) - Health Canada

Frequently Asked Questions (FAQ)

Common questions about Гемороль (FAQ)


Q: Does Гемороль actually treat the cause or just the symptoms of hemorrhoids?

The official product information specifies that the general purpose of Гемороль is to provide localized symptomatic relief.

This means its function is to address discomforts such as pain, burning, swelling, and irritation. It is not classified as a curative treatment intended to resolve the underlying cause of hemorrhoids.


Q: Will taking oral painkillers affect how Гемороль works?

Regulatory documents indicate a potential for interaction with other medications.

Specifically, if used alongside other Central Nervous System (CNS) Depressants, there is a possibility of experiencing additive CNS depression. Referencing the product information or consulting a healthcare provider is generally recommended for questions about specific oral medications.


Q: Does Гемороль help with both pain and itching?

The medicine’s official purpose is focused on the relief of local discomforts, including pain, burning, and irritation.

While itching (pruritus) is listed in official documents as a potential local side effect, the product’s overall intent is to provide relief from the general scope of anorectal discomfort.


Q: Can people with high blood pressure use Гемороль?

Regulatory documents advise caution or limitation for use in patients with certain tachyarrhythmias (rapid or irregular heart rhythms) due to the presence of Belladonna alkaloids.

Additionally, the drug's mechanism of action includes alpha-adrenergic stimulation, which causes localized vasoconstriction. Reviewing one's full medical history, including conditions like high blood pressure, with a healthcare professional is generally recommended.


Q: Does Гемороль contain any ingredients that might cause a mild allergic reaction?

Yes, the product information states that Гемороль is contraindicated if a person has a known hypersensitivity or allergy to any of its active substances or excipients.

As with any medication, there is always a potential for allergic reactions.


Q: Is it normal to feel a slight burning sensation right after inserting Гемороль?

According to the official safety profile, a burning sensation at the application site is listed as one of the common local reactions that users may experience.

If the burning sensation is severe or persists, referring to the guidelines in the product leaflet or seeking professional advice is appropriate.


Q: Can Гемороль be used for internal hemorrhoids, external hemorrhoids, or both?

The medicine is prepared as a rectal suppository, which is designed for localized application to the anorectal area.

This placement is appropriate for the symptomatic management of both internal and external hemorrhoidal symptoms.


Q: Can Гемороль be used for anal fissures as well as hemorrhoids?

Yes, the research evidence that supports the use of this type of medicine includes studies focused on patients with acute hemorrhoidal symptoms as well as those with anal fissures and mucosal irritation.

The medication’s properties address general anorectal discomfort.


Q: How should I store Гемороль to keep it effective?

To maintain the product’s stability and effectiveness, official requirements mandate that you store it at a temperature not exceeding 25 C.

It is also essential to keep the medicine in the original packaging until use.


Q: What is the research evidence supporting the use of Гемороль?

The evidence base for symptomatic management is drawn from studies focused on the product’s components and class of medicine.

This evidence typically involves short-term Randomized Controlled Trials (RCTs) and observational studies in adult patients dealing with acute and uncomplicated hemorrhoidal symptoms.


Q: Is Гемороль a herbal or a chemical-based medication?

Гемороль is formally defined as a specialized Herbal-Synthetic Combination Drug.

It contains a single synthetic compound, Bensocaine, combined with a complex phytocomplex made up of several natural plant extracts.


Q: Why is it recommended to use Гемороль after a bowel movement?

The administration guidelines state that the area should be cleansed and dried before insertion.

This preparation step is often done following a bowel movement to ensure proper hygiene for application.


Q: What happens if Гемороль gets absorbed into the bloodstream?

Regulatory warnings highlight rare but serious risks associated with systemic exposure from the components.

These potential systemic effects include the risk of Methemoglobinemia (from Bensocaine) and signs of systemic anticholinergic toxicity (from the Belladonna alkaloids).


Q: Does using Гемороль require any specific preparation beforehand?

Yes, the official administration guidelines require a few preparation steps.

Prior to use, the suppository must be removed from its foil packaging, and the local area must be cleansed and dried.


Q: Can I use Гемороль if I have a known allergy to plant-based products?

The medicine is contraindicated if you are allergic or hypersensitive to any of its components, which include multiple natural plant extracts in the phytocomplex.

If there are known allergies to plant-based products, consulting a healthcare provider to confirm suitability is generally appropriate.


Q: Are the side effects of Гемороль generally mild or more serious?

Official documents categorize the documented side effects into two groups.

They include Common (typically mild local reactions like burning or itching) and Rare (but more serious systemic reactions such as Methemoglobinemia or severe anticholinergic toxicity).


Q: How does the drug work to shrink hemorrhoids or reduce inflammation?

The medicine’s mechanism of action involves multiple steps.

It causes localized vasoconstriction and inhibits inflammatory mediators, which collectively work to restrict fluid from entering the surrounding tissue and stabilize the local vascular barrier.


Q: Does the efficacy of Гемороль decrease with prolonged use?

The medicine is authorized for short-term courses only, not to exceed seven consecutive days.

Regulatory documents note that long-term effects and continued symptomatic stability after the acute treatment period are not fully established in research.


Q: Where can I find reliable clinical studies on Гемороль?

Research evidence supporting the product is based on short-term Randomized Controlled Trials (RCTs) and observational studies.

These studies investigate the role of the product's components in relieving anorectal discomfort and are typically referenced by the National Drug Registry.


Q: What kind of relief should I realistically expect from Гемороль?

The product is intended for symptomatic management to improve local comfort.

Studies indicate that users report changes in symptoms like anal pain, burning, and muscular spasm/tension.


Q: Are there different formats of Гемороль available (e.g., suppositories vs. ointment)?

The official regulatory profile consistently defines and authorizes the product form as a Rectal Suppository.

No other formats (such as creams or ointments) are officially listed under this specific product's regulatory profile.

How should Гемороль be stored and disposed of?

Official Storage and Disposal Requirements

Regulatory documents define specific conditions under which Гемороль must be stored to maintain its stability and effectiveness. Adherence to these requirements is mandatory and ensures the product remains safe for use until its expiration date.

Storage Domain Official Requirement
Temperature Store at a temperature not exceeding 25°C (Controlled Room Temperature).
Child Safety Must be stored out of reach and sight of children.
Packaging Must be kept in the original package to ensure protection and stability.
Expiration Do not use the drug after the expiry date printed on the package.
Disposal Follow local and national guidelines for the disposal of unused or expired pharmaceutical waste.

Storing the product outside of the specified temperature range or after the printed expiration date is not permitted. Used or expired medicine should be handled according to established pharmaceutical waste procedures in the patient's locality.

Attention! Always consult to a doctor or pharmacist before using pills or medicines.

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