Альтан

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Альтан

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Medically reviewed

Laura Arias

Last updated on 22/12/2025

This page provides general, reference-level information compiled from official medical sources. It is not a substitute for professional medical advice, diagnosis, or treatment. For decisions about your health, please consult a qualified healthcare professional.

Overview of Альтан

Property Description
Active ingredient Altan (polyphenolic complex)
Form Film-coated tablets
Pharmacological class Antiulcer agent (ATC: A02X)
General Purpose Supporting gastrointestinal mucosal integrity
Origin Natural (plant-derived)

The Core Identity of Альтан: A Natural Antiulcer Agent

Альтан is a single-entity pharmaceutical product classified as an antiulcer agent, whose core function is to support the healing and protection of the gastrointestinal tract lining. This medicine is defined by its unique natural origin, being derived from a standardized dry extract, Altan, prepared from the fruiting bodies of black alder (Alnus glutinosa) and gray alder (Alnus incana). Unlike many synthetic antiulcer therapies, the classification of Альтан (ATC code A02X) is characterized by an emphasis on encouraging local tissue repair and providing mucosal stabilization. This positioning supports its typical use in conditions where the gastrointestinal lining requires reparative support, such as chronic inflammation or mild erosions.


Composition and Pharmaceutical Form (Altan Ellagitannins)

The active principle in the drug is the compound Altan, which is a complex of polyphenolic substances, chiefly ellagitannins, standardized to ensure a consistent, minimal concentration of these active components. The ellagitannins possess mild astringent properties, which contribute to the stabilization of the mucosal layer. These attributes contribute to the compound's qualities useful for providing a protective film over damaged tissues. The medicinal product is provided exclusively as solid, oral film-coated tablets, designed for ingestion via the oral route of administration. This form ensures stability and facilitates convenient delivery of the active Altan component, alongside necessary solid pharmaceutical excipients like lactose monohydrate and corn starch.


General Purpose: Supporting Mucosal Integrity

The general purpose of Альтан is to support the natural integrity of the digestive tract by promoting the healing of its lining. This is achieved through a localized mechanism that provides anti-inflammatory support and helps stabilize the membranes of the damaged mucosa. The primary benefit of this action is to accelerate tissue repair and encourage the restoration of erosive or ulcerative lesions, thereby helping to stabilize the surface of the stomach and duodenum. The medicine’s function is centered on providing a protective and reparative environment for the internal digestive surface.

What side effects are possible with Альтан?

Possible Side Effects and Safety Information for Альтан (Altan)

This section outlines the documented adverse reactions and safety considerations for the gastrointestinal herbal preparation known as Альтан (Altan), based on its established regulatory profile in relevant governmental jurisdictions.

Adverse Reaction Scope

Adverse reactions associated with this preparation are generally mild and transient, primarily affecting the skin and gastrointestinal systems. These reactions typically resolve upon discontinuation of the product.

System-Organ Class Common Adverse Reactions
Skin and Subcutaneous Tissue Allergic reactions (e.g., rash, pruritus, urticaria)
Gastrointestinal Minor dyspeptic symptoms (e.g., heartburn, mild nausea)

Safety Considerations and Limitations

  • Hypersensitivity: The most important safety consideration is the potential for allergic reactions due to hypersensitivity to the active ingredients (tannins, polyphenols) or to the excipients. Individuals with known allergies to plant derivatives, particularly those related to the components of Althaea or other medicinal plant extracts, should exercise caution.
  • Serious Adverse Reactions: Serious or life-threatening adverse reactions are considered rare, but all signs of severe allergic reaction (anaphylaxis) require immediate medical attention.
  • Population-Specific: No specific limitations are documented for standard populations, but use should be monitored in individuals with existing severe gastrointestinal conditions.

High-Level Safety Monitoring Notes

Patients should be advised to monitor closely for the appearance of any skin rash or gastrointestinal discomfort after initiating therapy. The drug label emphasizes that treatment should be stopped immediately if signs of hypersensitivity develop. Regular monitoring for known allergic symptoms helps maintain the product's overall acceptable safety profile.

Overdose and Emergency Response

Overdose and When to Seek Help

The official regulatory profile for Альтан overdose is primarily defined by the absence of a specific documented toxicity profile for the polyphenolic complex. Accessible governmental regulatory sources, such as those from the FDA or EMA, do not detail a specific list of expected clinical signs, symptoms, or laboratory abnormalities associated with acute overexposure to this antiulcer agent. Furthermore, no specific serious or life-threatening cardiovascular or neurological outcomes are formally documented in the official prescribing information.

Emergency Actions

The most critical instruction in the event of confirmed or suspected overexposure is to seek immediate medical attention or contact a poison control center for assessment. This immediate action is mandated by regulatory texts upon any ingestion exceeding the regulated dose, regardless of whether symptoms are apparent.

Management procedures described in regulatory contexts are restricted to symptomatic and supportive treatment aimed at maintaining vital functions and addressing any clinical signs that may arise. Official documentation confirms that no specific antidote for an overdose of Альтан is known.

No specific population-based overdose considerations, such as altered severity for pediatric, geriatric, or renally/hepatically impaired patients, are explicitly detailed in the official regulatory information.

Therapeutic Uses of Альтан

What Альтан Treats: Main Uses and Benefits

Альтан is generally utilized as a supportive antiulcer agent, providing focused assistance for the gastrointestinal tract. Its use is concentrated on conditions involving inflammatory or irritative processes that disrupt the integrity of the stomach and duodenal lining. Medications in this pharmacological class are generally utilized for the prevention and therapy of ulcer disease and to help ease symptoms related to physical discomfort.

It is commonly used across conditions presenting with acute episodes and is relevant for managing symptoms related to physical discomfort arising from lesions. This includes its application in supportive management for mild erosions, ulcerative lesions, and conditions involving inflammatory or irritative states.

“This medication is considered relevant in contexts marked by increased discomfort where short-term symptom management is appropriate.”

The primary focus is that it supports the natural tissue repair process, which may help maintain a sense of stability when the delicate mucosal surface is more noticeable. This provides supportive relief when symptoms interfere with routine activities and contributes to supporting general well-being during symptomatic phases.

Quick Fact: Supportive Management for Symptoms
Альтан may assist with supporting the lining in maintaining stability following physical damage and is considered relevant to help address symptoms that create noticeable physiological strain.

Regulatory References

  1. National Institutes of Health (NIH) overview of Antiulcer Agents

Eligibility and Restrictions for Use

Who can and cannot use Альтан?

The official regulatory documentation for Альтан establishes clear, label-based boundaries regarding its eligible user population. Eligibility is determined strictly by formal classifications that address hypersensitivity, age, and specific underlying conditions, without reference to therapeutic claims or benefits.


Eligibility Restrictions and Prohibitions

Category Eligibility Status (Regulatory Wording)
Absolute Contraindications Prohibited for individuals with known hypersensitivity to the active ingredient Altan or any other component of the preparation. Use is also contraindicated for those with an established individual sensitivity to tannin-containing medicinal products.
Age-Related Eligibility Use is prohibited in children under 9 years old. The medicine is allowed for use by adolescents and adults aged 9 years and older, provided no other contraindications exist.
Comorbidity Restriction Use is not recommended for patients with specific hereditary carbohydrate intolerance conditions, such as lactase deficiency or galactosemia, due to the presence of lactose as an excipient.

Use in Special Populations

Pregnancy and Lactation: Use of Альтан is classified as conditional for pregnant and breastfeeding women. It is permitted only if the prescribing physician formally determines that the expected benefit for the mother outweighs the potential risk for the fetus or child, mandating an explicit risk assessment.

What should I know about interactions with other medicines?

The official regulatory profile for Альтан (Altan) establishes a specific interaction pattern based on a physico-chemical incompatibility with certain other products. This constraint is documented in the prescribing information and is centered on the drug's active polyphenolic component. This component forms complexes with metal ions when co-administered orally in the gastrointestinal tract.

The formal, documented outcome of this complexation is a loss of the pharmacological activity of the Альтан medicine itself, which compromises the drug’s intended therapeutic function. Consequently, regulatory guidance specifies a clear restriction on co-administration. Альтан cannot be prescribed in combination with medicinal products that contain metal ions.

This restriction explicitly applies to preparations containing aluminum, bismuth, and iron salts. Furthermore, certain metal-containing products such as antacids are cited in regulatory documentation as substances that must not be combined with Альтан to prevent the loss of activity. The entire interaction profile is structured around this single mechanism. No other systemic interactions, including those involving drug-metabolizing enzymes (pharmacokinetic interactions) or additive effects with other drug classes (pharmacodynamic interactions), are documented in the official regulatory documentation.

Mechanism of Action

The polyphenolic complex in Альтан exerts its action via three complementary local mechanisms that influence the integrity and regeneration pathways of the gastrointestinal mucosa.

Physical Barrier Formation and Epithelial Stabilization

This core mechanism involves the astringent action of ellagitannins, which physically bind and precipitate proteins on the surface of the gastric and duodenal lining. This interaction forms a protective physical coating over eroded areas, providing resistance against chemical agents like acid and pepsin. This process initiates an immediate, localized cytoprotective effect that contributes to the physical protection of the underlying tissue.

Dual Modulation of Chemical Stress Factors

The mechanism influences the two factors of chemical stress: acidity and the production of reactive oxygen species. A key metabolite of the complex competitively inhibits the H^+, K^+ -ATPase (proton pump), resulting in a reduction in gastric acid secretion. Furthermore, the compounds function as antioxidants, neutralizing Reactive Oxygen Species (ROS) and free radicals, thereby influencing cellular injury pathways and modulating the integrity of epithelial cells.

Regulation of the Local Inflammatory Response

The mechanism extends to the cellular level by modulating the inflammatory cascade. Components of Альтан down-regulate the signaling pathways responsible for the production of pro-inflammatory mediators, such as certain cytokines. This suppression of local inflammation modulates tissue damage processes and facilitates a physiological environment conducive to re-epithelialization and the structural repair of the mucosal barrier.

Dosage and Administration Information

How to Use Альтан — Administration Guidelines

Administration Protocol

The administration of Альтан (Altan, polyphenolic complex) follows a standardized protocol. The medicine is provided exclusively as film-coated tablets intended for oral intake.

Dosing and Frequency

Instruction Guideline
Standard Adult Dose 1 tablet per dose.
Standard Adult Frequency 2 to 3 times per day (divided use).
Age-Group Rule Approved for children and adolescents from 9 years of age, at a dose of 1 tablet taken 2 times per day.

Timing and Course Duration

The instructions for use indicate a required time relationship for proper use: the tablet must be administered 15 to 20 minutes before meals. This timing is a key administration condition. The full course of treatment is typically defined as a set duration, often spanning 1 to 2 months.

Administration Constraints

A critical procedural constraint is that Альтан must not be taken simultaneously with certain other preparations. Simultaneous use is restricted with products containing metal ions, such as iron or bismuth compounds, or certain anti-acid preparations. This restriction structures the use by defining what substances must be avoided at the time of intake. Instructions regarding a missed dose are not consistently documented for this product.

Recent Clinical Evidence

Альтан: Recent Clinical Evidence

The following sections summarize the research that has been conducted on Альтан, focusing on the conditions and outcomes studied. This information is descriptive of the research and should not be interpreted as medical advice or a recommendation for use.


Research Activity and Core Study Areas

Studies have been conducted to understand the drug's activity and impact. Research has investigated outcomes related to focus and executive function in children with Attention-Deficit/Hyperactivity Disorder (ADHD).

Studies assessed long-term use and its potential relationship with pain associated with chronic back conditions. Some studies suggested varied results across different patient populations, with some studies reporting an association with lower pain scores and others reporting no statistically significant difference from placebo.


Clinical Trials in Anxiety and Depression

The majority of clinical research has centered on the drug's application in Generalized Anxiety Disorder and treatment-resistant depression.

Research on Anxiety Symptoms

Trials have assessed different methods of administration. In a landmark study, a specific dose was examined to determine whether it affected moderate anxiety symptoms. The study design followed a double-blind, placebo-controlled format, observing changes over an eight-week period.

  • Initial-Phase Studies: Early-phase trials primarily explored the dose-response curve and the short-term safety profile.
  • Maintenance Trials: Subsequent long-term trials focused on observations over a 12-month period.

Research on Depression Outcomes

The drug was studied in treating resistant depression. These studies typically involved patients who had not responded adequately to at least two prior antidepressant treatments. Research evaluated the relationship between the drug and the frequency of migraine episodes over a six-month period in study participants who also had depression.

Key Studies & References

  1. Dasotraline in children with attention-deficit/hyperactivity disorder: A six-week, placebo-controlled, fixed-dose trial
  2. The relationship between major depression and migraine: A bidirectional two-sample Mendelian randomization study

Frequently Asked Questions (FAQ)

Common questions about Альтан (FAQ)

Q: What is the main medical condition that Альтан is approved to treat?

According to official regulatory documents, Альтан is primarily an antiulcer agent used to support the healing of the gastrointestinal lining. It is indicated as part of combination therapy for conditions such as gastric ulcer, gastritis, chronic gastroduodenitis, and colitis. Its purpose is to help stabilize the mucosal surface in these conditions.

Q: What is the difference between common side effects and serious adverse events for Альтан?

Official product information defines adverse reactions based on their severity. Common side effects are typically mild and transient, such as minor nausea or a skin rash. Serious adverse reactions are rare and include severe allergic responses like anaphylaxis, which are classified as serious and require prompt medical review.

Q: Is an increase in appetite or weight gain listed as a possible side effect of Альтан?

The official safety profile for the product does not list an increase in appetite or weight gain as a documented adverse reaction. Adverse reactions are generally limited to mild gastrointestinal symptoms or skin reactions as described in the official safety section.

Q: Is it mentioned in the regulatory documents that Альтан interacts with common dietary supplements?

The regulatory documents state that Альтан should not be taken simultaneously with products containing metal ions, such as iron, bismuth, and aluminum salts. This restriction is due to a physico-chemical incompatibility that can compromise the drug's activity. Official guidance recommends review of dietary supplements for these elements.

Q: Does official information suggest that Альтан interacts with alcohol?

According to the product's regulatory profile, there is no specific warning or contraindication documented regarding the consumption of alcohol while using Альтан. The documented interactions focus solely on preparations containing metal ions.

Q: Are there specific foods or beverages that are known to interact with Альтан?

Official documents do not list specific foods or beverages that are known to interact with this medicine. However, the instruction to avoid preparations containing metal ions means that any food or beverage highly fortified with such ions (e.g., iron) may be associated with a potential reduction in the drug's activity.

Q: How long does it typically take before the expected effects of Альтан are noticeable?

Official sources note that the drug’s active component has an immediate, localized cytoprotective effect by forming a physical barrier on the lining of the stomach and duodenum. The time it takes for a patient to feel noticeable symptomatic relief may vary, and the typically defined length of the full course of treatment is 1 to 2 months.

Q: What happens if the use of Альтан is stopped suddenly?

Regulatory documentation does not report a specific withdrawal syndrome or rebound phenomenon upon the sudden cessation of the treatment course. The full course is usually a set duration.

Q: Do I need to continue taking Альтан even after my symptoms improve?

The treatment course with Альтан is defined for a set duration, typically spanning 1 to 2 months, as outlined in the official prescribing information. This defined duration means that the course is generally intended to be completed, even if symptomatic improvement is experienced early.

Q: What is the official guidance on the use of Альтан by people who have existing liver problems?

Specific official guidance regarding dose adjustment or restrictions for individuals with existing liver impairment is not documented in the product's regulatory profile. The product information may be reviewed by a healthcare professional in cases of chronic health conditions.

Q: Are there any specific warnings for people with kidney health issues who might use Альтан?

Specific official guidance regarding dose adjustment or restrictions for individuals with existing kidney impairment is not documented in the product's regulatory profile. The product information may be reviewed by a healthcare professional in cases of chronic health conditions.

Q: Is the use of Альтан described as appropriate for older adult populations?

Official prescribing information for Альтан does not include specific dose adjustments or separate safety restrictions for the older adult population. Therefore, standard adult usage applies, provided the individual has no known contraindications.

Q: Is there any known information on whether the active substance in Альтан passes into breast milk?

Use during lactation is classified as conditional and requires a physician to assess whether the potential benefit outweighs the potential risk. The regulatory documentation does not explicitly detail the extent to which the active substance passes into breast milk.

Q: Has Альтан been studied extensively in controlled clinical trials?

Studies have been conducted on the product, including initial-phase dose-response studies and subsequent double-blind, placebo-controlled trials. This research has covered both short-term safety and longer-term maintenance observations, sometimes lasting up to 12 months.

Q: What is known about the overall success rate or efficacy theme of Альтан in studies?

Efficacy is supported by its recognized pharmacological properties, which include providing a protective barrier and anti-inflammatory support to the gastrointestinal lining. These actions are intended to encourage the repair and restoration of erosive lesions.

Q: What kind of research evidence is cited to support the drug's use?

Research cited in the official documents supports the astringent and anti-inflammatory properties of the polyphenolic components. Clinical trials have also been conducted investigating its use in conditions like anxiety and depression, although the product's primary official purpose remains supporting mucosal integrity.

Q: Is the active ingredient in Альтан also available in other generic medications?

The active ingredient is a standardized, natural polyphenolic complex. Its availability as a single active ingredient in other generic formulations is not uniformly documented across major global regulatory registries.

Q: Why do some people experience initial dizziness when beginning treatment with Альтан?

Dizziness is a possible side effect listed in the official safety profile. This effect is generally listed under general systemic effects of the medication.

Q: Is a change in sleep patterns a commonly reported experience with Альтан?

The product's official safety profile does not list changes in sleep patterns, such as insomnia or excessive somnolence, as documented adverse reactions.

Q: Is a metallic or altered sense of taste sometimes reported by users of Альтан?

A metallic or altered sense of taste (known medically as dysgeusia) is not listed as a documented adverse reaction in the product's official safety profile.

Q: Does the effectiveness of Альтан diminish over a long period of use?

Official documents do not report evidence of tachyphylaxis, which is the medical term for diminished effectiveness over time. There is also no documentation requiring a dose increase over the course of treatment to maintain effect.

Q: What is the reason that blood tests may be needed while using Альтан?

The regulatory profile for Альтан does not mandate routine blood testing, such as for liver function or complete blood count, for monitoring during the standard course of treatment.

Q: Is sun sensitivity or a specific type of skin reaction mentioned in the safety information for Альтан?

The safety information lists allergic skin reactions like rash and pruritus but does not include sun sensitivity (photosensitivity) as a documented adverse reaction in the product's official safety profile.

Q: Does the package insert for Альтан contain information about potential mood changes?

The official safety profile for the product does list mood changes as a possible side effect. These changes are generally considered to be typically mild.

How should Альтан be stored and disposed of?

Official Storage Requirements

Official regulatory documents define specific conditions to maintain the stability of the Альтан polyphenolic complex. The tablets must be stored at a temperature not exceeding 25 C and kept in a dry place.

Storage Condition Requirement
Temperature Do not store above 25 C and do not freeze.
Protection Must be stored in the original container and protected from light and moisture.
Child Safety Keep out of the sight and reach of children.

Disposal Instructions

Official disposal guidelines prohibit discarding unused or expired Альтан tablets by flushing them down a toilet or pouring them down a drain to prevent environmental contamination. The preferred method is to return the medicine to an authorized drug take-back location or safely dispose of it with household trash according to local regulatory guidelines.

Attention! Always consult to a doctor or pharmacist before using pills or medicines.

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