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Method of action:
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Medically reviewed by Militian Inessa Mesropovna, PharmD. Last updated on 12.03.2022
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Inside.
Children over 6 years old and adults : initial dose - 5 mg (1/2 table. or 10 drops) once a day, if necessary, can be increased to 10 mg (1 table. or 20 drops) 1 time a day. Sometimes the initial dose is 5 mg (1/2 tab. or 10 drops) may be sufficient to achieve a therapeutic effect. Daily dose - 10 mg (1 table. or 20 drops).
Children from 6 to 12 months : 2.5 mg (5 drops) 1 time per day.
Children from 1 year to 2 years : 2.5 mg (5 drops) up to 2 times a day.
Children from 2 to 6 years old : 2.5 mg (5 drops) 2 times a day or 5 mg (10 drops) 1 time a day.
Sick with renal failure, the dose decreases depending on the creatinine clearance: with Cl creatinine 30–49 ml / min - 5 mg 1 time per day, at 10–29 ml / min - 5 mg per day.
Because of Ricam® excreted by kidneys, when prescribing the drug, patients with renal failure and elderly patients should be adjusted to the extent of creatinine clearance. Creatinin clearance for men can be calculated based on the concentration of serum creatinine, according to the following formula:
Cl creatinine, ml / min
Creatinine clearance for women can be calculated by multiplying the value obtained by a coefficient of 0.85.
Renal failure | Cl creatinine, ml / min | Dosing mode |
Missing (norm) | ≥80 | 10 mg / day |
Easy | 50–79 | 10 mg / day |
Medium | 30–49 | 5 mg / day |
Heavy | 10–29 | 5 mg per day |
The terminal stage is patients on hemodialysis | <10 | taking the drug is contraindicated |
For adult patients with renal and liver failure, dosing is carried out according to the table above.
Children with renal failure are adjusted for creatinine clearance and body weight.
Patients with impaired liver function only do not need to correct the dosing mode.
Inside.
Drops dissolve in a small amount of water before taking.
Adults and adolescents over 12 years old: 10 mg (20 drops or 1 table.) once a day, preferably at night.
Children aged 6–12 years: 5 mg each (10 drops or 1/2 table.) 2 times a day (morning and evening) or 10 mg (20 drops or 1 whole tablet) in the evening.
Children aged 1-6 years recommended to assign Ricam® in the medicinal form of a drop for taking in.
Children aged 2–6 years: 5 mg (10 drops per day) once. You can also divide this dose by 2 doses of 2.5 mg (5 drops in the morning and evening).
Children aged 1-2 years: 2.5 mg (5 drops) 2 times a day.
Special patient groups
It may be necessary to reduce the dose of y elderly patients.
At kidney function violation the dose should be set individually, in accordance with the function of the kidneys. The table below will assist in the selection of doses. To use this table, you should evaluate Cl creatinine in a patient in ml / min. After determining the concentration of creatinine of blood serum (mg / dl), the value of Cl creatinine can be estimated using the following formula:
Cl creatinine = [(140 − age, years) × body weight, kg) / (72 − creatinine blood serum, mg / dl]
When calculating creatinine clearance for women, the result must be multiplied by 0.85. The table shows the doses depending on Cl creatinine.
Table
The dose selection depending on the clearance of creatinine
Cl creatinine, ml / min | Dosage |
≥80 | 10 mg 1 time per day |
50–79 | 10 mg 1 time per day |
30–49 | 5 mg 1 time per day |
11–29 | 5 mg 1 time in 2 days |
≤10 (hemodialysis) | contraindicated |
Inside, dig into a spoon or dissolve in water.
The amount of water for dissolving the drug must correspond to the amount of fluid that the patient (especially the child) is able to swallow. The solution should be taken immediately after preparation.
Adults. 10 mg (20 drops) 1 time per day. Sometimes an initial dose of 5 mg (10 drops) can be enough if this allows satisfactory control of the symptoms.
Elderly age. In elderly patients with normal kidney function, there is no need to reduce the dose.
Violation of the function of the kidneys. When prescribing the drug to patients with impaired renal function, in the case when alternative treatment cannot be prescribed, the dose should be adjusted depending on the value of Cl creatinine, since cetyrizin is removed from the body mainly by the kidneys.
The Cl creatinine indicator for men can be calculated based on the concentration of serum creatinine in the blood plasma according to the following formula:
Cl creatinine, ml / min = (140 - age, years) × body weight, kg) / (72 × Cl creatinineserum, mg / dl).
Cl creatinine for women can be calculated by multiplying the value obtained by a coefficient of 0.85.
Renal failure | Cl creatinine, ml / min | Dosing mode |
Norma | ≥80 | 10 mg / day |
Easy | 50–79 | 10 mg / day |
Medium | 30–49 | 5 mg / day |
Heavy | <30 | 5 mg per day |
The terminal stage is patients on hemodialysis | <10 | The drug is contraindicated |
Violation of liver function. Patients with impaired liver function do not need to correct the dosing mode. In patients with impaired liver function and kidneys, dosing correction is recommended (see. table above).
Children. The use of children from 6 to 12 months is possible only by appointment of a doctor and under strict medical supervision. Children from 6 to 12 months — 2.5 mg (5 drops) 1 time a day; from 1 year to 6 years — 2.5 mg (5 drops) 2 times a day; from 6 to 12 years — 5 mg (10 drops) 2 times a day; over 12 years old — 10 mg (20 drops) 1 time a day, sometimes the initial dose is 5 mg (10 drops) may be enough, if this allows satisfactory control of the symptoms.
Children with renal failure are adjusted for Cl creatinine and body weight.
Instructions for opening a bottle
The bottle is closed with a lid with a safety device that prevents children from opening it. The bottle opens when the lid is pressed heavily down, followed by screwing it off counterclockwise. After using the bottle cover, you must screw it tight again.
Inside, swallowing in its entirety, drinking with a small amount of water, regardless of the time of eating.
Zinzet is used as prescribed by a doctor (to avoid complications).
Children from 2 to 6 years old: 2.5 mg each (1/2 h.syrup spoons) 2 times a day or 5 mg (1 h.spoon) 1 time per day; from 6 to 12 years: 10 mg each (1 table. or 2 hours. syrup spoons) 1 time per day or 5 mg (1/2 table. or 1 h.spoon syrup) 2 times a day, morning and evening; adults and children over 12 years old: 10 mg each (1 table. or 2 hours. spoons of syrup) 1 time per day.
For elderly people or patients with severe impaired liver and / or kidney function, the drug is prescribed individually by a doctor, in a reduced dose.
If the time of taking the drug is accidentally missed, the next dose should be taken as soon as possible. In the event that the time for the next drug is approaching, the next dose should be taken on schedule, without increasing the total dose.
Inside, swallowing in its entirety, drinking with a small amount of water, regardless of the time of eating.
Ricam is used as prescribed by a doctor (to avoid complications).
Children from 2 to 6 years old: 2.5 mg each (1/2 h.syrup spoons) 2 times a day or 5 mg (1 h.spoon) 1 time per day; from 6 to 12 years: 10 mg each (1 table. or 2 hours. syrup spoons) 1 time per day or 5 mg (1/2 table. or 1 h.spoon syrup) 2 times a day, morning and evening; adults and children over 12 years old: 10 mg each (1 table. or 2 hours. spoons of syrup) 1 time per day.
For elderly people or patients with severe impaired liver and / or kidney function, the drug is prescribed individually by a doctor, in a reduced dose.
If the time of taking the drug is accidentally missed, the next dose should be taken as soon as possible. In the event that the time for the next drug is approaching, the next dose should be taken on schedule, without increasing the total dose.