Quadriderm AF

Each gram of Betamethasone (Betamethasone Topical (Quadriderm AF)*) Cream* contains: 640 mcg betamethasone dipropionate (equivalent to 500 mcg betamethasone).

Each gram of Betamethasone (Betamethasone Topical (Quadriderm AF)*) Ointment* contains: 640 mcg betamethasone dipropionate (equivalent to 500 mcg betamethasone).

Betamethasone (Betamethasone Topical (Quadriderm AF)*) Cream and Ointment contain betamethasone dipropionate, a synthetic corticosteroid with anti-inflammatory activity to be administered topically.

Betamethasone dipropionate is a white to creamy white odorless crystalline powder insoluble in water; freely soluble in acetone and in chloroform; sparingly soluble in alcohol. It has a molecular weight of 504.16 and the empirical formula C₂₈H₃₇FO₇; a chemical name of 9-fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione,17,21-dipropionate.

Each gram of cream and topical powder contains clotrimazole 0.01 g.

Clotrimazole Topical (Quadriderm AF) Cream is odourless, can be washed off and does not stain.

A complex of three different closely related aminoglycoside sulfates, G-Myticins C1, C2, and C1(subA), obtained from Micromonospora purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit protein synthesis (genetic translation).

Betamethasone Topical (Quadriderm AF) is a potent topical corticosteroid indicated for adults, elderly and children >1 year for the relief of inflammatory and pruritic manifestations of steriod responsive dermatoses. These include atopic dermatitis (including infantile atopic dermatitis), nummular dermatitis (discoid eczema), prurigo nodularis, psoriasis (excluding widespread plague psoriasis), lichen simplex chronicus (neurodermatitis) and lichen planus, seborrhoeic dermatitis, irritant or allergic contact dermatitis, discoid lupus erythomatosus, adjunct to systemic steroid therapy in generalized erythroderma, insect bite reactions and miliaria (prickly heat).

Clotrimazole Topical (Quadriderm AF) Cream: Clotrimazole Topical (Quadriderm AF) cream is an antifungal cream used to treat skin infections caused by dermatophytes, fungi, yeasts, moulds, etc [eg, athlete's foot, jock itch, ringworm of the body, cutaneous candidiasis (candida infection of the skin which may occur in diaper areas in babies, in armpits, groins or areas under the breasts)], pityriasis versicolor (commonly called white spots).

Clotrimazole Topical (Quadriderm AF) cream can also be used for erythrasma (a skin infection caused by the bacteria Corynebacterium minutissimum and usually affects areas with skin folds eg, the groin, armpits, between toes).

Clotrimazole Topical (Quadriderm AF) cream can also be used for female fungal infections of the vaginal area. It can also be used in males where inflammation is present in the penis, caused by yeast fungi (Candida vulvitis and Candida balanitis).

Clotrimazole Topical (Quadriderm AF)

Topical Powder:

Clotrimazole Topical (Quadriderm AF) powder may be used as an adjuvant to the previously mentioned treatment or as a follow-up treatment (prevention of reinfection) of the previously mentioned fungal infections (dermatomycoses) and erythrasma.

Gentamicin Topical (Quadriderm AF) is indicated in a variety of infections caused by gentamicin-sensitive pathogens which includes the following: Infections of the respiratory tract eg, bronchitis and pneumonias, particularly those of a relapsing nature; prevention of pneumonia secondary to endotracheal intubation; infections of the urogenital tract eg, pyelonephritis, cystitis, urethritis and prostatitis; gonococcal infections including those caused by strains resistant to penicillin and other antibiotics; high-grade or deep-seated bacterial infections of the eyes; infections associated with severe burns; systemic septicemic infections.

Gentamicin Topical (Quadriderm AF) is excellently suited for controlling hospital infections, because it is active against the causative agents involved and because these have shown little loss of susceptibility to Gentamicin Topical (Quadriderm AF).

Betamethasone is a topical steroid. It reduces the actions of chemicals in the body that cause inflammation, redness, and swelling.

Betamethasone Topical (Quadriderm AF) is used to treat the inflammation caused by a number of conditions such as allergic reactions, eczema, and psoriasis. The dental paste form of betamethasone is used to treat mouth ulcers.

Betamethasone Topical (Quadriderm AF) may also be used for other purposes not listed in this medication guide.

Clotrimazole Topical (Quadriderm AF) is an antifungal medication that fights infections caused by fungus.

Clotrimazole Topical (Quadriderm AF) (for the skin) is used to treat skin infections such as athlete's foot, jock itch, ringworm, and yeast infections.

Clotrimazole Topical (Quadriderm AF) may also be used for purposes not listed in this medication guide.

Gentamicin is an antibiotic that fights bacteria.

Gentamicin Topical (Quadriderm AF) (for use on the skin) is used to treat skin infections caused by bacteria.

Gentamicin Topical (Quadriderm AF) may also be used for purposes not listed in this medication guide.

Shake well before use.

Apply Betamethasone Topical (Quadriderm AF) Spray to the affected skin areas twice daily and rub in gently.

Use Betamethasone Topical (Quadriderm AF) Spray for up to 4 weeks of treatment. Treatment beyond 4 weeks is not recommended.

Discontinue Betamethasone Topical (Quadriderm AF) Spray when control is achieved.

Do not use if atrophy is present at the treatment site.

Do not bandage, cover, or wrap the treated skin area unless directed by a physician.

Avoid use on the face, scalp, axilla, groin, or other intertriginous areas.

Betamethasone Topical (Quadriderm AF) Spray is for topical use only. It is not for oral, ophthalmic, or intravaginal use.

How supplied

Dosage Forms And Strengths

Spray, 0.05% for topical use. Each gram of Betamethasone Topical (Quadriderm AF) Spray contains 0.643 mg betamethasone dipropionate USP (equivalent to 0.5 mg betamethasone) in a slightly thickened, white to off-white oil-in-water emulsion.

Storage And Handling

Betamethasone Topical (Quadriderm AF) Spray is a slightly thickened, white to off-white, non-sterile emulsion supplied in high density polyethylene bottles with a heat induction seal lined polypropylene cap. The drug is supplied in the following volumes:

60 mL (NDC 67857-808-17)

120 mL (NDC 67857-808-04)

Store at controlled room temperature of 20°C to 25°C (68°F to 77°F), excursions permitted to 15°C to 30°C (59°F to 86°F).

Each unit is co-packaged with a manual spray pump for installation by the pharmacist prior to dispensing.

Handling/Instructions For The Pharmacist

1. Remove the spray pump from the wrapper.
2. Remove and discard the cap from the bottle.
3. Keeping the bottle upright, insert the spray pump into the bottle and turn clockwise until it is closed tightly.
4. Dispense the bottle with the spray pump inserted.
5. Include the date dispensed in the space provided on the carton.

Manufactured by: DPT Laboratories, Ltd., San Antonio, TX 78215 Distributed by: Promius Pharma, LLC., Princeton, NJ 08540. Revised: Jan 2016.

Usual Adult Dose for Tinea Corporis:

Apply Clotrimazole Topical (Quadriderm AF) in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 4 weeks, depending on the nature and severity of the infection.

Usual Adult Dose for Tinea Cruris:

Apply Clotrimazole Topical (Quadriderm AF) in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 2 weeks, depending on the nature and severity of the infection.

Usual Adult Dose for Tinea Pedis:

Apply Clotrimazole Topical (Quadriderm AF) in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 4 to 8 weeks, depending on the nature and severity of the infection.

Usual Adult Dose for Cutaneous Candidiasis:

Apply Clotrimazole Topical (Quadriderm AF) in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 2 to 4 weeks, depending on the nature and severity of the infection.

Usual Adult Dose for Tinea Versicolor:

Apply Clotrimazole Topical (Quadriderm AF) in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 2 to 4 weeks, depending on the nature and severity of the infection.

Usual Adult Dose for Vaginal Candidiasis:

Regimen 1: 100 mg (one 100 mg vaginal suppository) intravaginally once a day for 7 consecutive days alone or in combination with topical application of 1% clotrimazole cream to affected area two times daily for 7 consecutive days.

Regimen 2: 200 mg (one 200 mg vaginal suppository) intravaginally once a day for 3 consecutive days alone or in combination with topical application of 1% clotrimazole cream to affected area two times daily for 7 consecutive days.

Regimen 3: 500 mg (one 500 mg vaginal suppository) intravaginally once.

Regimen 4: One applicatorful of 1% clotrimazole vaginal cream intravaginally once daily (preferably at bedtime) for 7 consecutive days.

Regimen 5: One applicatorful of 2% clotrimazole vaginal cream intravaginally once daily (preferably at bedtime) for 3 consecutive days.

Studies have shown the three and seven day courses of clotrimazole to be equally effective. Patient compliance may be increased with a three day course. Patients who fail to achieve a cure with a single 500 mg dose should be treated with a 3 or 7 day course of clotrimazole.

Weekly or monthly clotrimazole vaginal suppositories appear to be effective topical regimens for chronic suppressive therapy in female patients with HIV.

Usual Pediatric Dose for Tinea Corporis:

> 3 years: Apply Clotrimazole Topical (Quadriderm AF) in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 4 weeks, depending on the nature and severity of the infection.

Usual Pediatric Dose for Tinea Cruris:

> 3 years: Apply Clotrimazole Topical (Quadriderm AF) in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 2 weeks, depending on the nature and severity of the infection.

Usual Pediatric Dose for Tinea Pedis:

> 3 years: Apply Clotrimazole Topical (Quadriderm AF) in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 4 to 8 weeks, depending on the nature and severity of the infection.

Usual Pediatric Dose for Cutaneous Candidiasis:

> 3 years: Apply Clotrimazole Topical (Quadriderm AF) in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 2 to 4 weeks, depending on the nature and severity of the infection.

Usual Pediatric Dose for Tinea Versicolor:

> 3 years: Apply Clotrimazole Topical (Quadriderm AF) in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 2 to 4 weeks, depending on the nature and severity of the infection.

Usual Pediatric Dose for Vaginal Candidiasis:

> 12 years: Regimen 1: 100 mg (one 100 mg vaginal suppository) intravaginally once a day for 7 consecutive days alone or in combination with topical application of 1% clotrimazole cream to affected area two times daily for 7 consecutive days.

Regimen 2: 200 mg (one 200 mg vaginal suppository) intravaginally once a day for 3 consecutive days alone or in combination with topical application of 1% clotrimazole cream to affected area two times daily for 7 consecutive days.

Regimen 3: 500 mg (one 500 mg vaginal suppository) intravaginally once.

Regimen 4: One applicatorful of 1% clotrimazole vaginal cream intravaginally once daily (preferably at bedtime) for 7 consecutive days.

Studies have shown the three and seven day courses of clotrimazole to be equally effective. Patient compliance may be increased with a three day course. Patients who fail to achieve a cure with a single 500 mg dose should be treated with a 3 or 7 day course of clotrimazole.

Weekly or monthly clotrimazole vaginal suppositories appear to be effective topical regimens for chronic suppressive therapy in female patients with HIV.

Topical Dosage

Medically reviewed on August 13, 2018.

Applies to the following strengths: 0.1%

Usual Adult Dose for:

• Skin and Structure Infection

Usual Pediatric Dose for:

• Skin and Structure Infection

Additional dosage information:

• Renal Dose Adjustments
• Liver Dose Adjustments
• Precautions
• Dialysis
• Other Comments

Usual Adult Dose for Skin and Structure Infection

Apply a small amount topically to lesions 3 to 4 times a day

Comments:

-Cream or ointment should be applied gently.

-Area may be covered with a gauze dressing if desired.

-In the treatment of impetigo contagiosa, the crusts should be removed prior to application of this drug to permit maximum contact between antibiotic and infection.

Uses: For the treatment of primary skin infections (e.g., impetigo contagiosa, superficial folliculitis, ecthyma, furunculosis, sycosis barbae, and pyoderma gangrenosum); for the treatment of secondary skin infections (e.g., infectious eczematoid dermatitis, pustular acne, pustular psoriasis, infected seborrheic dermatitis, infected contact dermatitis [including poison ivy], infected excoriations, and bacterial superinfections of fungal or viral infections)

Usual Pediatric Dose for Skin and Structure Infection

Greater than 1 year: Apply a small amount topically to lesions 3 to 4 times a day

Comments:

-Cream or ointment should be applied gently.

-Area may be covered with a gauze dressing if desired.

-In the treatment of impetigo contagiosa, the crusts should be removed prior to application of this drug to permit maximum contact between antibiotic and infection.

Uses: For the treatment of primary skin infections (e.g., impetigo contagiosa, superficial folliculitis, ecthyma, furunculosis, sycosis barbae, and pyoderma gangrenosum); for the treatment of secondary skin infections (e.g., infectious eczematoid dermatitis, pustular acne, pustular psoriasis, infected seborrheic dermatitis, infected contact dermatitis [including poison ivy], infected excoriations, and bacterial superinfections of fungal or viral infections)

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Safety and efficacy have not been established in patients younger than 1 year.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

-For topical use only.

-Care should be taken to avoid further contamination of the infected skin.

-Infected stasis ulcers have responded adequately to this drug under gelatin packing.

General:

-This drug is a bactericidal agent that is not effective against viruses or fungi in skin infections.

-This drug is useful in the treatment of infected skin cysts and certain other skin abscesses when preceded by incision and drainage to permit adequate contact between the antibiotic and the infecting bacteria.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

More about Gentamicin Topical (Quadriderm AF)

• Gentamicin Topical (Quadriderm AF) Side Effects
• During Pregnancy or Breastfeeding
• Drug Interactions
• Pricing & Coupons
• En Español
• 1 Review
• Drug class: topical antibiotics

Consumer resources

• Gentamicin Topical (Quadriderm AF)
• Gentamicin (Topical)
• Gentamicin

  Topical (Advanced Reading)

Other brands: Gentamicin Topical (Quadriderm AF), Garamycin

Topical

Professional resources

• Gentamicin Sulfate topical (AHFS Monograph)
• ... +3 more

Related treatment guides

• Paronychia
• Skin and Structure Infection

See also:
What is the most important information I should know about Betamethasone Topical (Quadriderm AF)?

Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts or for longer than recommended.

Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to. If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Covering the skin that is treated with Betamethasone Topical (Quadriderm AF) can increase the amount of the drug your skin absorbs, which may lead to unwanted side effects. Follow your doctor's instructions.

Avoid using this medication on your face, near your eyes, or on body areas where you have skin folds or thin skin.

Do not use this medication on a child without a doctor's advice. Children are more sensitive to the effects of Betamethasone Topical (Quadriderm AF).

Betamethasone Topical (Quadriderm AF) will not treat a bacterial, fungal, or viral skin infection.

Contact your doctor if your condition does not improve or if it gets worse after using this medication for several days.

See also:
What is the most important information I should know about Clotrimazole Topical (Quadriderm AF)?

Clotrimazole Topical (Quadriderm AF) Cream: Hypersensitivity to clotrimazole, cetostearyl alcohol or to any other components of Clotrimazole Topical (Quadriderm AF) Cream.

Clotrimazole Topical (Quadriderm AF)

Topical Powder:

See also:
What is the most important information I should know about Gentamicin Topical (Quadriderm AF)?

Hypersensitivity to gentamicin is a contraindication to its use. A history of hypersensitivity or serious toxic reactions to other aminoglycosides may contraindicate use of gentamicin because of the known cross-sensitivity of patients to drugs in this class.

This medicine is usually applied 1 or 2 times daily. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Do not take by mouth. Betamethasone Topical (Quadriderm AF) is for use only on the skin.

Wash your hands before and after using this medicine, unless you are using the medicine to treat the skin on your hands.

Apply a small amount to the affected area and rub it gently into the skin. Do not apply Betamethasone Topical (Quadriderm AF) over a large area of skin.

To use Betamethasone Topical (Quadriderm AF) foam, spray some of the foam onto a plate or other cool surface. Pick up a small amount of the foam with your fingers and gently massage it into your scalp. Repeat until all affected areas are treated.

Do not cover the treated skin area unless your doctor tells you to. Covering the skin that is treated with Betamethasone Topical (Quadriderm AF) can increase the amount of medicine your skin absorbs, which may lead to unwanted side effects. Follow your doctor's instructions.

When treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers.

Use Betamethasone Topical (Quadriderm AF) regularly to get the most benefit. Stop using the medicine once your symptoms clear up.

You should not use Betamethasone Topical (Quadriderm AF) for longer than 4 weeks.

Call your doctor if your skin condition does not improve after several days of treatment, or if it gets worse while using Betamethasone Topical (Quadriderm AF).

Store at room temperature away from moisture and heat.

The foam is flammable. Do not use near high heat or open flame. Do not smoke until the foam has completely dried on your skin.

Use Clotrimazole Topical (Quadriderm AF) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Clotrimazole Topical (Quadriderm AF). Talk to your pharmacist if you have questions about this information.
• Clotrimazole Topical (Quadriderm AF) is for vaginal use only. Do not use it rectally or take by mouth.
• Suppositories - Using the applicator provided, insert 1 suppository high into the vagina at bedtime for 7 days.
• Clotrimazole Topical (Quadriderm AF) comes with one applicator to be used for all 7 days of treatment. Do not throw away applicator after use. Separate the pieces of the applicator and wash with warm, soapy water immediately after use. Rinse thoroughly. Make sure the applicator is completely dry before the next use.
• External cream - Squeeze a small amount of cream onto your finger and gently spread the cream onto the itchy, irritated skin outside the vagina as directed by your doctor or on the packaging.
• Wash your hands immediately after using Clotrimazole Topical (Quadriderm AF).
• To clear up your infection completely, use Clotrimazole Topical (Quadriderm AF) for the full course of treatment. Keep using it even if you feel better in a few days.
• If you miss a dose of Clotrimazole Topical (Quadriderm AF), use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Clotrimazole Topical (Quadriderm AF).

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Before you apply Gentamicin Topical (Quadriderm AF), wash and thoroughly dry the infected skin.

Gently wash away any crusts from the infected skin. This will help the medicine better penetrate the infection more easily

Apply a small amount of Gentamicin Topical (Quadriderm AF) to the affected area.

Cover the skin with a gauze dressing if desired.

Keep your hands and skin clean to avoid further infection.

Store at room temperature away from moisture and heat.

This medication is used to treat a variety of skin conditions (e.g., eczema, dermatitis, allergies, rash). Betamethasone reduces the swelling, itching, and redness that can occur in these types of conditions. This medication is a strong corticosteroid.

How to use Betamethasone Topical (Quadriderm AF) topical

Use this medication on the skin only. However, do not use it on the face, groin, or underarms or for diaper rash unless directed to do so by your doctor.

Wash and dry your hands. Before applying the medication, clean and dry the affected area. Apply a thin film of the medication to the affected area and gently rub in, usually 1-2 times daily or as directed by your doctor.

Do not cover, bandage, or wrap the area unless directed to do so by your doctor. If your doctor directs you to use this medication in the diaper area on an infant, do not use tight-fitting diapers or plastic pants.

If you are using the lotion form of this medication, shake the bottle well before each dose.

After applying the medication, wash your hands unless you are using this medication to treat the hands. When applying this medication near the eyes, avoid getting it in the eyes as this may worsen or cause glaucoma. Also, avoid getting this medication in the nose or mouth. If you get the medication in these areas, rinse with plenty of water.

Use this medication only for the condition for which it was prescribed. Do not use it for longer than prescribed.

Inform your doctor if your condition persists or worsens after 2 weeks.

Clotrimazole Topical (Quadriderm AF) is used for the treatment of fungal infections of the vagina, mouth, ear and skin, such as athlete's foot, jock itch, ringworm, thrush, or otitis externa (inflammation of outer ear).

This medication is used to treat minor skin infections (such as impetigo, folliculitis) or minor infections related to some skin conditions (such as eczema, psoriasis, minor burns/cuts/wounds). Gentamicin works by stopping the growth of certain bacteria. It belongs to a class of drugs known as aminoglycoside antibiotics.

This antibiotic only treats bacterial infections. It will not work for virus or fungus infections. Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness.

How to use Gentamicin Topical (Quadriderm AF) topical

This medication is for use on the skin only.

Wash your hands before using. Clean and dry the affected area as directed. If you are treating impetigo, remove any dried, crusty skin to increase contact between the antibiotic and the infected area. Then gently apply a small amount of medication in a thin layer as directed by your doctor, usually 3 to 4 times a day. You may cover the area with a sterile gauze bandage if so directed. Keep the infected area clean. Wash your hands after use, unless you are using this product to treat the hands.

Avoid getting this medication in your eyes, nose, or mouth. If this occurs, wipe off the medication and rinse thoroughly with water.

Dosage and length of treatment is based on your medical condition and response to treatment.

Use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day. Do not apply large amounts of this medication, use it more often, or use it for longer than prescribed. Your condition will not improve any faster, and your risk of side effects may increase.

Continue to use this medication for the full length of treatment prescribed, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a return of the infection.

Tell your doctor if your skin infection persists or if it worsens.

See also:
What other drugs will affect Betamethasone Topical (Quadriderm AF)?

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to salicylic acid or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Young children may be at increased risk of unwanted effects because of increased absorption of salicylic acid through the skin. Also, young children may be more likely to get skin irritation from salicylic acid. Salicylic acid should not be applied to large areas of the body, used for long periods of time, or used under occlusive dressing (air-tight covering, such as kitchen plastic wrap) in infants and children. Salicylic acid should not be used in children younger than 2 years of age.

Geriatric

Elderly people are more likely to have age-related blood vessel disease. This may increase the chance of problems during treatment with salicylic acid.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

See also:
What other drugs will affect Clotrimazole Topical (Quadriderm AF)?

Simultaneous administration of Clotrimazole Topical (Quadriderm AF) with amphotericin B, nystatin, natamycin activity of clotrimazole decreases.

See also:
What other drugs will affect Gentamicin Topical (Quadriderm AF)?

The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring.

To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval.

Some products that may interact with this drug include: aminoglycoside antibiotics given by injection (such as amikacin, gentamicin, tobramycin).

This document does not contain all possible drug interactions. Keep a list of all the products you use. Share this list with your doctor and pharmacist to lessen your risk for serious medication problems.

See also:
What are the possible side effects of Betamethasone Topical (Quadriderm AF)?

Clinical Trials Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.

In two randomized, multicenter, prospective vehicle-controlled clinical trials, subjects with moderate plaque psoriasis of the body applied Betamethasone Topical (Quadriderm AF) Spray or vehicle spray twice daily for 4 weeks. A total of 352 subjects applied Betamethasone Topical (Quadriderm AF) Spray and 180 subjects applied vehicle spray.

Adverse reactions that occurred in at least 1% of subjects treated with Betamethasone Topical (Quadriderm AF) Spray for up to 28 days are presented in Table 1.

Less common adverse reactions (with occurrence lower than 1% but higher than 0.1%) in subjects treated with Betamethasone Topical (Quadriderm AF) spray were application site reactions including telangiectasia, dermatitis, discoloration, folliculitis and skin rash, in addition to dysgeusia and hyperglycemia. These adverse reactions were not observed in subjects treated with vehicle.

Postmarketing Experience

Because adverse reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Postmarketing reports for local adverse reactions to topical corticosteroids have also included striae, irritation, dryness, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, secondary infection, hypertrichosis, and miliaria.

See also:
What are the possible side effects of Clotrimazole Topical (Quadriderm AF)?

Applies to Clotrimazole Topical (Quadriderm AF): topical cream, topical lotion, topical solution

In addition to its needed effects, some unwanted effects may be caused by Clotrimazole Topical (Quadriderm AF) (the active ingredient contained in Clotrimazole Topical (Quadriderm AF)). In the event that any of these side effects do occur, they may require medical attention.

Severity: Moderate

If any of the following side effects occur while taking Clotrimazole Topical (Quadriderm AF), check with your doctor or nurse as soon as possible:

• Skin rash, hives, blistering, burning, itching, peeling, redness, stinging, swelling, or other sign of skin irritation not present before use of this medicine

See also:
What are the possible side effects of Gentamicin Topical (Quadriderm AF)?

Applies to Gentamicin Topical (Quadriderm AF): topical cream, topical ointment

In addition to its needed effects, some unwanted effects may be caused by Gentamicin Topical (Quadriderm AF) (the active ingredient contained in Garamycin

Topical). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking Gentamicin Topical (Quadriderm AF):

Less common:

• Itching, redness, swelling, or other sign of irritation not present before use of this medicine