Q-TOX

Calcium chloride is an ionic compound of calcium and chlorine. It is highly soluble in water and it is deliquescent. It is a salt that is solid at room temperature, and it behaves as a typical ionic halide. It has several common applications such as brine for refrigeration plants, ice and dust control on roads, and in cement. It can be produced directly from limestone, but large amounts are also produced as a by-product of the Solvay process. Because of its hygroscopic nature, it must be kept in tightly-sealed containers.

Each film-coated tablet contains EGb 761^® [dry extract from Ginkgo biloba (Q-TOX) leaves (35-67:1)]; Extraction Agent: Acetone 60% (m/m).

The extract in each film-coated tablet is quantified to flavonoids 26.4-32.4 mg, calculated as flavone glycosides, and terpene lactones 6.48-7.92 mg of which gingkgolides A, B, C 3.36-4.08 mg as well as bilobalide 3.12-3.84 mg, and contains ginkgolic acids <0.6 mcg.

Ginkgo biloba (Q-TOX) also contains the following excipients: Croscarmellose sodium, colloidal silica; hypromellose, lactose monohydrate, macrogol 1500; magnesium stearate; maize starch, microcrystalline cellulose, dimethicone, α-octadecyl-ω-hydroxypoly(oxyethylene)-5; talcum; titanium dioxide E171; iron oxide E172.

Lycopene (Q-TOX), an antioxidant, is indicated for the treatment and prevention of cancer, cataract, asthma, HPV infection, atherosclerosis, CVD and prostate cancer. Lycopene (Q-TOX) is a good anti-inflammatory agent and anti-oxidant.

Each ampoule also contains D-mannitol 50 mg as an additive. pH 5.3-7.3. Osmotic Pressure (to physiological saline): Approximately 1.

Mecobalamin is α-(5,6-dimethylbenzimidazolyl)-Co-methyl-cobamide.

Molecular Formula: C₆₃H₉₁CoN₁₃O₁₄P.

Molecular Weight: 1344.4.

Mecobalamin occurs as a dark red, odorless and almost tasteless crystal or crystalline powder. It is sparingly soluble in water, methanol and ethanol and practically insoluble in acetone, ether and chloroform. Mecobalamin is hygroscopic and decomposes upon exposure to light.

Each capsule contains Co-enzyme Q10 25 mg and 50 mg, respectively.

Ubidecarenone (Q-TOX) also contains fractionated coconut oil as an inactive ingredient.

Vitamin B12 (Q-TOX) (commonly known as Vitamin B12 (Q-TOX)) is the most chemically complex of all the vitamins. Vitamin B12 (Q-TOX)'s structure is based on a corrin ring, which, although similar to the porphyrin ring found in heme, chlorophyll, and cytochrome, has two of the pyrrole rings directly bonded. The central metal ion is Co (cobalt). Vitamin B12 (Q-TOX) cannot be made by plants or by animals, as the only type of organisms that have the enzymes required for the synthesis of cyanocobalamin are bacteria and archaea. Higher plants do not concentrate cyanocobalamin from the soil and so are a poor source of the substance as compared with animal tissues. Vitamin B12 (Q-TOX) is naturally found in foods including meat (especially liver and shellfish), eggs, and milk products.

A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Vitamin E (Q-TOX)&

Zinc (Q-TOX) Capsule: Each capsule contains Zinc (Q-TOX) sulphate monohydrate 54.93 mg, thiamine nitrate 10 mg, riboflavin 10 mg, pyridoxine hydrochloride 3 mg, Zinc (Q-TOX) (coated) equivalent to cyanocobalamin 15 mcg, ascorbic acid 150 mg, folic acid 1 mg, nicotinamide 50 mg and calcium pantothenate 12.5 mg.

Zinc (Q-TOX) Syrup: Each 5 mL contains Zinc (Q-TOX) gluconate 34.9 mg, thiamine mononitrate 2.5 mg, riboflavin 2.5 mg, pyridoxine hydrochloride 1 mg, cyanocobalamin 3 mcg, ascorbic acid 50 mg, d-panthenol 12.5 mg and niacinamide 25 mg in a flavoured liquid glucose sorbitol syrup base.

Ascorbate calcium is the calcium salt form of ascorbic acid (also known as vitamin C) that is used to prevent and treat scurvy, a vitamin C deficiency. Vitamin C may also be used in persons with chronic illness, burns, certain blood disorders, or as dietary supplement.

Oral

Nutritional supplementation

Adult: Usual dose range: 125-250 mg 1-2 times daily. Dosing instruction may vary according to the product used.

dietary supplement

Improvement of memory, concentration and mental alertness.

Prevention of further degeneration of cognitive function, social functioning ability and depressive mood associated with dementia syndromes eg, Alzheimer's and vascular dementia. Tinnitus, vertigo, peripheral arterial occlusive disease, improves blood circulation.

Note: Prior to starting treatment with Ginkgo extract, clarification should be obtained as to whether the pathological symptoms encountered are not based on an underlying disease requiring a specific treatment.

Improvement of the pain-free walking distance in peripheral arterial occlusive disease in Fontaine stage II (intermittent claudication) within the framework of physical therapeutic measures, in particular walking training.

Vertigo of vascular and involutional origin.

Adjuvant treatment in case of tinnitus of vascular and involutional origin.

Frequently occurring dizziness and tinnitus always need to be clarified by a physician.

In case of sudden hearing deficit or hearing loss, patient should immediately consult a physician.

These compounds act mainly as normalizatoare of cellular metabolic process. ale fenomenelor oxidative si de imbatranire. Alterations mentioned processes underlying degenerative processes of cell aging and oxidative phenomena

Tab: Treatment of peripheral neuropathies. Inj: Megaloblastic anemia due to vit B₁₂ deficiency, peripheral neuropathies.

Oral

Selenium (Q-TOX) deficiency

Adult: 100-500 mcg of Selenium (Q-TOX) daily.

Intramuscular

Selenium (Q-TOX) deficiency

Adult: 100-500 mcg of Selenium (Q-TOX) daily.

Intravenous

Selenium (Q-TOX) deficiency

Adult: 100-500 mcg of Selenium (Q-TOX) daily.

R & D - Ubidecarenone (Q-TOX) (Origin) is used as a heart energizer and antioxidant to fight against free radicals in the body. It serves as an energy booster for patients suffering from high-cholesterol, hypertension, congestive heart failure (CHF), and other heart related problems.

Pernicious anemia, both uncomplicated and accompanied by nervous system involvement.

Dietary deficiency of Vitamin B12 (Q-TOX), occurring in strict vegetarians and in their breast-fed infants. (Isolated Vitamin B12 (Q-TOX) deficiency is very rare).

Malabsorption of Vitamin B12 (Q-TOX), resulting from structural or functional damage to the stomach, where intrinsic factor is secreted or to the ileum, where intrinsic factor facilitates Vitamin B12 (Q-TOX) absorption. These conditions include tropical sprue, and nontropical sprue (idiopathic steatorrhea, gluten-induced enteropathy). Folate deficiency in these patients is usually more severe than Vitamin B12 (Q-TOX) deficiency.

Inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (ingestion of corrosives, extensive neoplasia), and a number of conditions associated with a variable degree of gastric atrophy (such as multiple sclerosis, certain endocrine disorders, iron deficiency, and subtotal gastrectomy). Total gastrectomy always produces Vitamin B12 (Q-TOX) deficiency.

Structural lesions leading to Vitamin B12 (Q-TOX) deficiency include regional ileitis, ileal resections, malignancies, etc.

Competition for Vitamin B12 (Q-TOX) by intestinal parasites or bacteria.

The fish tapeworm (Diphyilobothrium latum) absorbs huge quantities of Vitamin B12 (Q-TOX) and infested patients often have associated gastric atrophy. The blind-loop syndrome may produce deficiency of Vitamin B12 (Q-TOX) or folate.

Inadequate utilization of Vitamin B12 (Q-TOX). This may occur if antimetabolites for the vitamin are employed in the treatment of neoplasia.

For the Schilling Test.

Oral

Vitamin E (Q-TOX) deficiency

Adult: 40-50 mg of d-α tocopherol daily.

Child: Neonate: 10 mg/kg once daily; 1 mth-18 yr: 2-10 mg/kg/day, up to 20 mg/kg.

Oral

Supplementation in cystic fibrosis

Adult: 100-200 mg daily of dl-α-tocoferil acetate or 67-135 mg daily of d-α-tocopherol.

Child: As α- tocopheryl acetate: 1 mth-1 yr 50 mg once daily; 1-12 yr 100 mg once daily; 12-18 yr 200 mg once daily. Dose to be adjusted as needed.

Oral

Abetalipoproteinaemia

Adult: 50-100 mg/kg daily of dl-α-tocoferil acetate or about 33-67 mg/kg daily of d-α-tocopherol.

Child: Neonate: 100 mg/kg once daily; 1 mth-18 yr: 50-100 mg/kg once daily.

Patients with deficiency of B-complex vitamins, vitamin C and Zinc (Q-TOX) or where supplementation of these vitamins and Zinc (Q-TOX) can be beneficial. Such patients and conditions include: Patients who are on prolonged antibiotic therapy; those who are suffering from infection, injuries, burns, fever, illness; patients with diarrhoea and GI disorders; patients who have undergone surgical operations; patients on diet restrictions eg, in diabetes, anorexia and alcoholism and in elderly persons; pregnant and lactating women due to increased nutritional needs.

Circulation and memory loss due to brain conditions such as stroke, Alzheimer disease, and dementia. It may also have other uses. Check with your pharmacist for more details regarding the particular brand you use.

Ginkgo biloba (Q-TOX) is an herbal product. It works by increasing blood flow to the brain.

Methylcobalamin (Q-TOX) is a form of vitamin B12. Vitamin B12 is important for the brain and nerves, and for the production of red blood cells.

Methylcobalamin (Q-TOX) is used to treat vitamin B12 deficiency. Methylcobalamin (Q-TOX) is sometimes used in people with pernicious anemia, diabetes, and other conditions.

Methylcobalamin (Q-TOX) may also be used for purposes not listed in this medication guide.

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Selenium (Q-TOX) is mineral that is found in soil and occurs naturally in certain foods (such as whole grains, Brazil nuts, sunflower seeds, and seafood). Selenium (Q-TOX) is not produced in the body, but it is needed for proper thyroid and immune system function.

Selenium (Q-TOX) is used to treat or prevent Selenium (Q-TOX) deficiency.

Selenium (Q-TOX) has been used in alternative medicine as an aid to treat Hashimoto's thyroiditis (an autoimmune disorder of the thyroid), and to treat high cholesterol.

Not all uses for Selenium (Q-TOX) have been approved by the FDA. Selenium (Q-TOX) should not be used in place of medication prescribed for you by your doctor.

Selenium (Q-TOX) may also be used for purposes not listed in this product guide.

Ubiquinone is a vitamin-like substance that is made naturally in the body. Ubiquinone is also known as Coenzima, Ubidcarenone, Ubidécarénone, and Ubiquinol.

Ubiquinone has been used in alternative medicine as a likely effective aid in treating coenzyme Q-10 deficiency, or reducing the symptoms of mitochondrial disorders (conditions that affect energy-production in the cells of the body).

Ubiquinone is also possibly effective in preventing migraine headaches, lowering blood pressure, preventing a second heart attack, or slowing the progression of early Parkinson's disease. Ubiquinone is also possibly effective in improving symptoms in people with congestive heart failure, nerve problems caused by diabetes, Huntington's disease, muscular dystrophy, or macular degeneration (age-related vision loss).

Ubiquinone has also been used to treat Alzheimer's disease, high cholesterol, or amyotrophic lateral sclerosis (Lou Gehrig's disease). However, research has shown that ubiquinone may not be effective in treating these conditions.

Research also has shown that ubiquinone is not likely to be effective in increasing athletic performance.

Other uses not proven with research have included treating asthma, COPD, cancer, diabetes, certain heart problems, fibromyalgia, hepatitis C, kidney problems, high blood pressure during pregnancy, muscle problems caused by taking "statin" cholesterol medicine, and other conditions.

Ubiquinone is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

Ubiquinone may also be used for purposes not listed in this product guide.

Cyanocobalamin is a man-made form of Vitamin B12 (Q-TOX). Vitamin B12 (Q-TOX) is important for growth, cell reproduction, blood formation, and protein and tissue synthesis.

Cyanocobalamin is used to treat Vitamin B12 (Q-TOX) deficiency in people with pernicious anemia and other conditions.

Cyanocobalamin may also be used for purposes not listed in this medication guide.

Vitamin E (Q-TOX) is an antioxidant that occurs naturally in foods such as nuts, seeds, and leafy green vegetables. Vitamin E (Q-TOX) is a fat-soluble vitamin important for many processes in the body.

Vitamin E (Q-TOX) is used to treat or prevent Vitamin E (Q-TOX) deficiency. People with certain diseases may need extra Vitamin E (Q-TOX).

Vitamin E (Q-TOX) may also be used for purposes not listed in this medication guide.

Zinc (Q-TOX) is a naturally occurring mineral. Zinc (Q-TOX) is important for growth and for the development and health of body tissues.

Zinc (Q-TOX) sulfate is used to treat and to prevent Zinc (Q-TOX) deficiency.

Zinc (Q-TOX) sulfate may also be used for purposes not listed in this medication guide.

Caplet Adult 1 caplet 1-2 times daily. Adolescent & childn >8 yr ½ caplet 1-2 times daily. Susp Childn 1-3 tsp once daily.

Oral

Nutritional supplementation

Adult: Usual dose range: 125-250 mg 1-2 times daily. Dosing instruction may vary according to the product used.

Normal

Dosage: 1 tab daily. For more intensive use, 1 tab may be taken twice daily. The intake of Ginkgo biloba (Q-TOX) is independent of meals.

Tablet: Adults: Usual Daily Dose: 3 tabs, equivalent to a total of 1500 mcg of mecobalamin, administered orally in 3 divided doses. The dose should be adjusted according to age of patient and severity of symptoms.

Injection: Peripheral Neuropathies: The usual adult dosage is 1 amp, equivalent to 500 mcg of mecobalamin administered IM or IV 3 times a week. The dosage should be adjusted according to age of patient and severity of symptoms.

Megaloblastic Anemia: The usual adult dosage is 1 amp, equivalent to 500 mcg of mecobalamin administered IM or IV 3 times a week. After approximately 2 months of medication, the dose should be reduced to a single administration of 1 amp at 1- to 3-month intervals for maintenance therapy.

Selenium (Q-TOX) Injection provides 40 mcg Selenium (Q-TOX)/mL. For metabolically stable adults receiving TPN, the suggested additive dosage level is 20 to 40 mcg Selenium (Q-TOX)/day. For pediatric patients, the suggested additive dosage level is 3 mcg/kg/day.

In adults, Selenium (Q-TOX) deficiency states resulting from long-term TPN support, Selenium (Q-TOX) as selenomethionine or selenious acid, administered intravenously at 100 mcg/day for a period of 24 and 31 days, respectively, has been reported to reverse deficiency symptoms without toxicity.

Aseptic addition of Selenium (Q-TOX) Injection to the TPN solution under laminar flow hood is recommended. Selenium (Q-TOX) is physically compatible with the electrolytes and other trace elements usually present in amino-acid/dextrose solution used for TPN. Frequent monitoring of plasma Selenium (Q-TOX) levels is suggested as a guideline for subsequent administration. The normal whole blood range for Selenium (Q-TOX) is approximately 10 to 37 mcg/100 mL.

Parenteral drug products should be inspected visually for particulate matter and discoloration, whenever solution and container permit.

Oral

Heart failure

Adult: 50-150 mg daily in 2-3 divided doses.

Oral

Angina pectoris

Adult: 150-600 mg daily in divided doses.

Vitamin B12 (Q-TOX) Atlantic Laboratories is used as injections SC, IV, IM, intralumbar, and also oral. With anemia associated with Vitamin B12 (Q-TOX) deficiency is introduced on 100-200 mcg in 2 days. In anemia with symptoms of funicular myelosis and megalocytic anemia with diseases of the nervous system - 400-500 micrograms in the first 7 days daily, then 1 time every 5-7 days. In the period of remission in the absence of events funicular myelosis maintenance dose - 100 mcg 2 times a month, in the presence of neurological symptoms - at 200-400 mcg 2-4 times a month. In acute post-hemorrhagic anemia and iron anemia by 30-100 mcg 2-3 times a week. When aplastic anemia (especially in children) - 100 micrograms before clinical improvement. When nutritional anemia in infants and preterm - 30 mcg / day during 15 days.

In diseases of the central and peripheral nervous system and neurological diseases with a pain syndrome is administered in increasing doses - 200-500 mcg, with the improvement in the state - 100 mcg / day. The course of treatment with Vitamin B12 (Q-TOX) Atlantic Laboratories is 2 weeks. In traumatic lesions of peripheral nervous system - at 200-400 mcg every other day for 40-45 days.

When hepatitis and cirrhosis - 30-60 mcg / day or 100 mg every other day for 25-40 days.

Dystrophy in young children, Down syndrome and cerebral palsy - by 15-30 mcg every other day.

When funicular myelosis, amyotrophic lateral sclerosis can be introduced into the spinal canal at 15-30 mcg, gradually increasing the dose of 200-250 micrograms.

In radiation sickness, diabetic neuropathy, sprue - by 60-100 mcg daily for 20-30 days.

When deficiency of Vitamin B12 (Q-TOX) to prevent - IV or IM for 1 mg 1 time a month; for treatment - IV or IM for 1 mg daily for 1-2 weeks, the maintenance dose is 1-2 mg IV or IM from 1 per week, up to 1 per month. Duration of treatment is determined individually.

Usual Adult Dose for Vitamin E (Q-TOX) Deficiency

Treatment: 60 to 75 units orally once daily.

Prevention: 30 units orally once daily.

Usual Adult Dose for Tardive Dyskinesia

600 to 1600 units orally per day.

Usual Adult Dose for Sickle Cell Anemia

450 units orally per day.

Usual Adult Dose for Alzheimer's Disease

1000 units orally twice daily.

Usual Adult Dose for Dietary Supplement

Oral liquid formulation (Vitamin E (Q-TOX)): 200 units (10 mL) orally once daily.

Usual Pediatric Dose for Vitamin E (Q-TOX) Deficiency

1 unit/kg/day orally of water-miscible Vitamin E (Q-TOX).

Usual Pediatric Dose for Retinopathy Prophylaxis

Prevention of retinopathy of prematurity or Bronchopulmonary dysplasia (BPD) secondary to oxygen therapy: 15 to 30 units/kg/day to maintain plasma levels between 1.5 to 2 mcg/mL (may need as high as 100 units/kg/day). Note: AAP considers this use investigational and routine use is not recommended.

Usual Pediatric Dose for Cystic Fibrosis

100 to 400 units/day orally.

Usual Pediatric Dose for Dietary Supplement

Dosing: 1 unit Vitamin E (Q-TOX) = 1 mg dl-alpha-tocopherol acetate.

Oral:

Adequate Intake (AI):

1 to less than 6 months: 4 units daily

6 to less than 12 months: 5 units daily

Recommended Daily Allowance (RDA):

1 to 3 years: 6 units daily

4 to 8 years: 7 units daily

9 to 13 years: 11 units daily

13 years and Older: 15 units daily

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Although no longer available in the U.S., Vitamin E (Q-TOX) injectable administered intravenously to premature infants may result in a potentially fatal syndrome consisting of thrombocytopenia, hepatomegaly, splenomegaly, ascites, and renal, hepatic, and pulmonary dysfunction.

Oral administration of large doses (200 mg per day) of a hyperosmolar Vitamin E (Q-TOX) preparation to low-birthweight infants has been associated with the development of necrotizing enterocolitis.

Dialysis

Data not available

Other Comments

The oral liquid formulation (Vitamin E (Q-TOX) [R]) is intended to enhance absorption in patients with conditions associated with malabsorption (e.g., Crohn's disease, ulcerative colitis ) or for patients who have difficulty swallowing capsules.

The oral liquid formulation (Vitamin E (Q-TOX) [R]) may be taken directly or mixed with water or other beverage. It must be shaken well prior to each use and refrigerated after opening.

Zinc (Q-TOX) 1 mg/mL (Zinc (Q-TOX) Chloride Injection, USP) contains 1 mg Zinc (Q-TOX)/mL and is administered intravenously only after dilution. The additive should be diluted prior to administration in a volume of fluid not less than 100 mL. For the metabolically stable adult receiving TPN, the suggested intravenous dosage is 2.5 to 4 mg Zinc (Q-TOX)/day (2.5 to 4 mL/day). An additional 2 mg Zinc (Q-TOX)/day (2 mL/day) is suggested for acute catabolic states. For the stable adult with fluid loss from the small bowel, an additional 12.2 mg Zinc (Q-TOX)/liter of small bowel fluid lost (12.2 mL/liter of small bowel fluid lost), or an additional 17.1 mg Zinc (Q-TOX)/kg of stool or ileostomy output (17.1 mL/kg of stool or ileostomy output) is recommended. Frequent monitoring of Zinc (Q-TOX) blood levels is suggested for patients receiving more than the usual maintenance dosage level of Zinc (Q-TOX).

For full term infants and children up to 5 years of age, 100 mcg Zinc (Q-TOX)/kg/day

(0.1 mL/kg/day) is recommended. For premature infants (birth weight less than 1500 g) up to 3 kg in body weight, 300 mcg Zinc (Q-TOX)/kg/day (0.3 mL/kg/day) is suggested.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. See PRECAUTIONS.

How supplied

Zinc (Q-TOX) 1 mg/mL (Zinc (Q-TOX) Chloride Injection, USP) is supplied in 10 mL Plastic Vials (List No. 4090).

Store at 20 to 25°C (68 to 77°F).

HOSPIRA, INC., LAKE FOREST, IL 60045 USA. Revised: October, 2004

. Hypersensitivity to the active substances or to any of the excipients of the effervescent tablet

. Diseases and/or conditions resulting in hypercalcaemia and/or hypercalciuria

. Nephrocalcinosis, nephrolithiasis

Hypersensitivity to Ginkgo biloba (Q-TOX) or to any of the excipients of Ginkgo biloba (Q-TOX).

Use in lactation: It is unknown whether Ginkgo biloba (Q-TOX)/metabolites are excreted in human milk. A risk to the newborns/infants cannot be excluded. Ginkgo biloba (Q-TOX) should not be used during breastfeeding.

Most Significant

Lactating Mother, Pregnancy, Prostatic Carcinoma, Selenium Toxicity, Wilson’s Disease

Possibly Significant

Vitamin K Deficiency Induced Hypoprothrombinemia

See also:
What is the most important information I should know about Selenium (Q-TOX)?

Selenium (Q-TOX) Injection should not be given undiluted by direct injection into a peripheral vein because of the potential for infusion phlebitis.

See also:
What is the most important information I should know about Ubidecarenone (Q-TOX)?

Young children, pregnant or lactating women or those with severe liver or kidney diseases.

Hypersensitivity to the components of the formula. History of allergy to the cobalamins (Vitamin B12 (Q-TOX) and similar substances). Malignant tumors. By stimulating the growth of tissues, the Cobamamide could increase the high rate of cell multiplication. Sensitivity to cobalt. History of allergies to cobalamin (Vitamin B12 (Q-TOX) and related substances).

- Malignant tumor: Due to the action of Vitamin B12 (Q-TOX) on the growth of tissue cell multiplication rate high, the risk of exacerbation should be taken into account.

- Children under 6 years because of the dosage form

See also:
What is the most important information I should know about Vitamin E (Q-TOX)?

Hypersensitivity to Vitamin E (Q-TOX) or any component of the formulation

See also:
What is the most important information I should know about Zinc (Q-TOX)?

Hypersensitivity to any of the ingredients of Zinc (Q-TOX).

Use Ginkgo biloba (Q-TOX) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Dosing depends on the use and the source of the product.
• Use as directed on the package, unless instructed otherwise by your doctor.
• If you miss taking a dose of Ginkgo biloba (Q-TOX) for 1 or more days, there is no cause for concern. If your doctor recommended that you take it, try to remember your dose every day.

Ask your health care provider any questions you may have about how to use Ginkgo biloba (Q-TOX).

Use Selenium (Q-TOX) lotion as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Shake well before each use.
• Remove jewelry before using Selenium (Q-TOX) lotion.
• Do not use on broken or inflamed skin or scalp.
• To use Selenium (Q-TOX) lotion on the scalp - Massage 1 or 2 teaspoonfuls of the medicine on the wet scalp. Leave on the scalp for 2 to 3 minutes. Rinse scalp thoroughly. Wash hands well after treatment. If you are using Selenium (Q-TOX) lotion before or after bleaching, tinting, or permanent waving of hair, rinse hair for at least 5 minutes in cool running water.
• To use Selenium (Q-TOX) lotion on the skin - Apply a sufficient amount to cover affected areas of the body. Lather well with a small amount of water. Leave the medicine on the skin for 10 minutes. Rinse thoroughly in the shower. Wash hands well after treatment.
• If you miss a dose of Selenium (Q-TOX) lotion, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once

Ask your health care provider any questions you may have about how to use Selenium (Q-TOX) lotion.

This medication is used to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets. It may be used to treat conditions caused by low calcium levels such as bone loss (osteoporosis), weak bones (osteomalacia/rickets), decreased activity of the parathyroid gland (hypoparathyroidism), and a certain muscle disease (latent tetany). It may also be used in certain patients to make sure they are getting enough calcium (e.g., women who are pregnant, nursing, or postmenopausal, people taking certain medications such as phenytoin, phenobarbital, or prednisone).

Calcium plays a very important role in the body. It is necessary for normal functioning of nerves, cells, muscle, and bone. If there is not enough calcium in the blood, then the body will take calcium from bones, thereby weakening bones. Having the right amount of calcium is important for building and keeping strong bones.

How to use Calcium ascorbate (Q-TOX)

Take this medication by mouth with food. If your product contains calcium citrate, then it may be taken with or without food. Follow all directions on the product package, or take as directed by your doctor. For best absorption, if your daily dose is more than 600 milligrams, then divide your dose and space it throughout the day. If you are uncertain about any of the information, consult your doctor or pharmacist.

If you are using the chewable product, chew it well before swallowing.

If you are using the effervescent tablet, allow the tablet to fully dissolve in a glass of water before drinking it. Do not chew or swallow the tablet whole.

If you are using the liquid product or powder, measure the medication with a dose-measuring spoon or device to make sure you get the correct dose. Do not use a household spoon. If the liquid product is a suspension, shake the bottle well before each dose.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

If your doctor has recommended that you follow a special diet, it is very important to follow the diet to get the most benefit from this medication and to prevent serious side effects. Do not take other supplements/vitamins unless ordered by your doctor.

If you think you may have a serious medical problem, seek immediate medical attention.

Docosahexaenoic acid (Q-TOX) (DHA) is used to prevent age related macular degeneration (loss of vision due to aging), coronary artery disease (blockage in arteries supplying blood to the heart), high cholesterol, type II diabetes, attention deficit hyperactive disorder (a type of brain disorder in which there are problems paying attention, excessive activity or difficulty controlling behavior), stroke, menstrual pain (dysmenorrhea) and memory disorders. DHA in combination with Eicosapentaenoic acid (EPA) is prescribed for the treatment of heart diseases, bipolar disorders (a mental condition marked by alternating periods of elation and depression), rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints), renal diseases, Systemic lupus erythematosus (a type of autoimmune disorder), asthma and ulcerative colitis (disease causing inflammation and ulcer in the colon).

To delay the progression and reduce symptoms of diabetic neuropathy and other associated symptoms of diabetes mellitus particularly in subjects with good blood sugar control and limited microangiopathy.

Cerebrovascular and peripheral activator, dementia.

Methylcobalamin (Q-TOX) is an active form of vitamin B12, which is used to treat anemia as well as nerve damage with numbness, tingling, pain in various neurological disorders.

Selenium (Q-TOX) is used as a dietary supplement mainly in the treatment of Selenium (Q-TOX) deficiency affecting young women and children with Keshan disease. It is also used for treatment of osteoarthiritis associated with poor Selenium (Q-TOX) levels in body called Kashin-Beck Disease. Selenium (Q-TOX) supplements are also used in patients with HIV/ AIDS to maintain the adequate Selenium (Q-TOX) levels.

Coenzyme Q10 has been used for heart problems (e.g., heart failure, angina), high blood pressure, Parkinson's disease, gum disease, and certain diseases passed down through families (Huntington's disease, muscular dystrophy). It has also been used for preventing migraine headaches and for preventing cell damage that may occur after surgery or treatment with certain anti-cancer drugs. If you have or think you have any of the conditions listed above, consult your doctor for advice on proper care and treatment.

Coenzyme Q10 is a substance that your body normally makes. Your body uses it to help keep in good health.

Some herbal/diet supplement products have been found to contain possibly harmful impurities/additives. Check with your pharmacist for more details about the brand you use.

The FDA has not reviewed this product for safety or effectiveness. Consult your doctor or pharmacist for more details.

How to use Ubidecarenone (Q-TOX)

This product is taken by mouth as directed. Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.

If you are using a liquid or powder form, carefully measure your dose using a medication-measuring device or spoon. Do not use a household spoon because you may not get the correct dose. If your liquid form is a suspension, shake the bottle well before measuring each dose. If your liquid comes in a tube/ampule, take the dose immediately after opening and discard any left over liquid. Follow the manufacturer's directions for mixing the powder form.

If you are using chewable tablets or wafers, chew each dose thoroughly before swallowing.

If you are using a tablet made to dissolve in the mouth, dry your hands before handling the tablet. Place each dose on the tongue and allow to dissolve completely, then swallow it with saliva or water.

Do not crush or chew extended-release tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.

If your condition persists or worsens, or if you think you may have a serious medical problem, seek immediate medical attention.

This supplement is used to prevent or treat a lack of Vitamin E (Q-TOX) in the body. A low body level of Vitamin E (Q-TOX) is rare. Most people who eat a normal diet do not need extra Vitamin E (Q-TOX). However, Vitamin E (Q-TOX) supplements are used in premature newborns and in people who have problems absorbing enough Vitamin E (Q-TOX) from their diets. Vitamin E (Q-TOX) is important in protecting your body's cells from damage. It is known as an antioxidant.

How to use Vitamin E (Q-TOX)

Take this product by mouth as directed. Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.

If you are using a liquid form of this product, carefully measure your dose using a medication-measuring device or spoon. Do not use a household spoon because you may not get the correct dose. If your liquid form is a suspension, shake the bottle well before each dose.

Dosage is based on your medical condition and response to treatment. Do not increase your dose or take it more often than recommended. Taking too much Vitamin E (Q-TOX) may increase your risk of side effects.

High doses of Vitamin E (Q-TOX) (400 units or more per day) may increase the chance of rare but very serious side effects. There is no proof that high doses of Vitamin E (Q-TOX) help to prevent or treat heart disease. There is very little evidence that it helps prevent or treat Alzheimer's disease. In some people, taking these high doses may even be harmful. Talk to your doctor or pharmacist and discuss the risks and benefits before taking Vitamin E (Q-TOX) supplements.

If your doctor prescribes this product for Vitamin E (Q-TOX) deficiency, use it regularly to get the most benefit from it. To help you remember, take it at the same time each day. You should see improvement of symptoms such as numbness/tingling of the hands/feet and weakness. If your condition persists or worsens, or if you think you may have a serious medical problem, seek immediate medical attention.

Tell your doctor of all prescription and nonprescription drugs you may use, especially of: vitamin and mineral supplements. If you take aspirin on a regular schedule, consult your doctor before taking ascorbic acid. This product can affect the results of certain lab tests, including tests for blood sugar. Diabetics should consult their doctor or pharmacist for the correct way to test their blood sugar levels while taking large amounts of ascorbic acid. Make sure laboratory personnel and your doctor(s) know you use this product. Do not start or stop any medicine without doctor or pharmacist approval.

Monitor prothrombin time when used with anticoagulant medications (including warfarin), aspirin or aspirin-containing products, NSAIDs, antiplatelet agents (e.g. ticlopidine, clopidogrel, dipyridamole). May increase hypotension when used with antihypertensive medications.

In case of simultaneous application of Ginkgo biloba (Q-TOX) with coagulation-inhibiting drugs (eg, phenprocoumon, warfarin, clopidogrel, acetylsalicylic acid and other nonsteroidal antirheumatics) it cannot be excluded that the effect of these medicines are enhanced.

As for all medicinal preparations, it cannot be excluded that Ginkgo biloba (Q-TOX) acts on the metabolization of other different medicinal preparations which may influence the potency and/or duration of the effect of the preparation concerned. There are no sufficient investigations available on these effects. Inform the physician if administering or have recently taken any other medicines including medicines obtained without prescription.

ALPHA TOCOPHERYL/SELECTED ANTICOAGULANTS - Increased effect of the latter drug

DI-TRIVALENT CATIONS/TETRACYCLINES - Decreased effect of the latter drug

Moderate Interaction:

Assess the risk to the patient and take action as needed.

POLYVALENT CATIONS/ELTROMBOPAG - Decreased effect of the latter drug

SELECTED MINERALS/ORAL IRON SUPPLEMENTS - Decreased effect of the latter drug

DI-; TRIVALENT CATIONS/CHLOROQUINE; HYDROXYCHLOROQUINE - Decreased effect of the former drug

ORAL MULTIVALENT CATIONS/ORAL BISPHOSPHONATES - Decreased effect of the latter drug

FAT SOLUBLE VITAMINS/ORLISTAT - Decreased effect of the former drug

ORAL ZINC PRODUCTS/SELECTED ORAL QUINOLONES - Decreased effect of the latter drug

See also:
What other drugs will affect Selenium (Q-TOX)?

Baloxavir Marboxil: Polyvalent Cation Containing Products may decrease the serum concentration of Baloxavir Marboxil. Avoid combination

Bictegravir: Polyvalent Cation Containing Products may decrease the serum concentration of Bictegravir. Management: Administer bictegravir under fasting conditions at least 2 hours before or 6 hours after polyvalent cation containing products. Coadministration of bictegravir with or 2 hours after most polyvalent cation products is not recommended. Consider therapy modification

Bisphosphonate Derivatives: Polyvalent Cation Containing Products may decrease the serum concentration of Bisphosphonate Derivatives. Management: Avoid administration of oral medications containing polyvalent cations within: 2 hours before or after tiludronate/clodronate/etidronate; 60 minutes after oral ibandronate; or 30 minutes after alendronate/risedronate. Exceptions: Pamidronate; Zoledronic Acid. Consider therapy modification

Deferiprone: Polyvalent Cation Containing Products may decrease the serum concentration of Deferiprone. Management: Separate administration of deferiprone and oral medications or supplements that contain polyvalent cations by at least 4 hours. Consider therapy modification

Dolutegravir: Selenium (Q-TOX) may decrease the serum concentration of Dolutegravir. Management: Administer dolutegravir at least 2 hours before or 6 hours after oral Selenium (Q-TOX). Administer the dolutegravir/rilpivirine combination product at least 4 hours before or 6 hours after oral Selenium (Q-TOX). Consider therapy modification

Eltrombopag: Polyvalent Cation Containing Products may decrease the serum concentration of Eltrombopag. Management: Administer eltrombopag at least 2 hours before or 4 hours after oral administration of any polyvalent cation containing product. Consider therapy modification

Elvitegravir: Polyvalent Cation Containing Products may decrease the serum concentration of Elvitegravir. Management: Administer elvitegravir 2 hours before or 6 hours after the administration of polyvalent cation containing products. Consider therapy modification

PenicillAMINE: Polyvalent Cation Containing Products may decrease the serum concentration of PenicillAMINE. Management: Separate the administration of penicillamine and oral polyvalent cation containing products by at least 1 hour. Consider therapy modification

Raltegravir: Polyvalent Cation Containing Products may decrease the serum concentration of Raltegravir. Management: Administer raltegravir 2 hours before or 6 hours after administration of the polyvalent cations. Dose separation may not adequately minimize the significance of this interaction. Consider therapy modification

Trientine: Polyvalent Cation Containing Products may decrease the serum concentration of Trientine. Management: Avoid concomitant administration of trientine and oral products that contain polyvalent cations. If oral iron supplements are required, separate the administration by 2 hours. If other oral polyvalent cations are needed, separate administration by 1 hour. Consider therapy modification

See also:
What other drugs will affect Ubidecarenone (Q-TOX)?

If you are taking this product under your doctor's direction, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

Before using this product, tell your doctor or pharmacist of all prescription and nonprescription medications you may use, especially of: drugs for high blood pressure, "blood thinners" (e.g., warfarin), drugs for diabetes, drugs for high cholesterol (e.g., atorvastatin, lovastatin).

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

In an application of Vitamin B12 (Q-TOX) Atlantic Laboratories with hormonal contraceptives for oral administration may decrease the concentration of cyanocobalamin in plasma.

In an application with anticonvulsant drugs decreased cyanocobalamin absorption from the gut.

In an Vitamin B12 (Q-TOX) Atlantic Laboratories application with neomycin, aminosalicylic acid, colchicine, cimetidine, ranitidine, drugs potassium decreased cyanocobalamin absorption from the gut.

Cyanocobalamin may exacerbate allergic reactions caused by thiamine.

When parenteral application of chloramphenicol may decrease the hematopoietic effects of cyanocobalamin with anemia.

See also:
What other drugs will affect Vitamin E (Q-TOX)?

Agents with Antiplatelet Properties (e.g., P2Y12 inhibitors, NSAIDs, SSRIs, etc.): Vitamin E (Q-TOX) (Systemic) may enhance the antiplatelet effect of Agents with Antiplatelet Properties. Monitor therapy

Anticoagulants: Vitamin E (Q-TOX) (Systemic) may enhance the anticoagulant effect of Anticoagulants. Monitor therapy

CycloSPORINE (Systemic): Vitamin E (Q-TOX) (Systemic) may decrease the serum concentration of CycloSPORINE (Systemic). Monitor therapy

Ibrutinib: Vitamin E (Q-TOX) (Systemic) may enhance the antiplatelet effect of Ibrutinib. Monitor therapy

Orlistat: May decrease the serum concentration of Vitamins (Fat Soluble). Management: Administer oral fat soluble vitamins at least 2 hours before or after the administration of orlistat. Similar precautions do not apply to parenterally administered fat soluble vitamins. Consider therapy modification

Tipranavir: May enhance the adverse/toxic effect of Vitamin E (Q-TOX) (Systemic). Management: Patients taking tipranavir oral solution are advised to avoid taking additional Vitamin E (Q-TOX), beyond the amounts contained in a multivitamin product. This interaction does not apply to tipranavir capsules. Consider therapy modification

See also:
What other drugs will affect Zinc (Q-TOX)?

Pyridoxine reduces the effects of levodopa (but this does not occur if a dopa decarboxylase is also given); decreases serum concentrations of phenobarbitone. Concurrent administration of drugs eg, isoniazid, penicillamine and oral contraceptives increase the requirement for pyridoxine.

Absorption of cyanocobalamin from the GIT may be reduced by neomycin, aminosalicylic acid, histamine H₂-receptor antagonists and colchicine. Serum concentrations may be decreased by concurrent administration of oral contraceptives. Many of these interactions are unlikely to be of clinical significance but should be taken into account when performing assays for blood concentrations.

Parenteral chloramphenicol may attenuate the effect of Zinc (Q-TOX) in anaemia.

Folate deficiency states may be produced by a number of drugs including antiepileptics, oral contraceptives, antituberculous drugs, alcohol and folic acid antagonists eg, aminopterin, methotrexate, pyrimethamine, trimethoprim and sulphonamides; folic acid may decrease serum-phenytoin concentrations.

There may be an increased risk of myopathy or rhabdomyolysis when nicotinic acid is used concurrently with statins. Nicotinamide may increase the requirements for insulin or oral hypoglycaemics.

Ascorbic acid may increase the absorption of iron-deficiency states.

Ascorbic acid is often given in addition to desferrioxamine to patients with iron overload (thalassemia) to achieve better iron excretion. However, early on in treatment when there is excess tissue iron, there is some evidence that ascorbic acid may worsen the iron toxicity, particularly to the heart. Thus, ascorbic acid should not be given for the first month after starting desferrioxamine treatment.

The absorption of Zinc (Q-TOX) may be reduced by iron supplements, penicillamine, phosphorus-containing preparations and tetracyclines. Zinc (Q-TOX) supplements reduce the absorption of copper, ciprofloxacin, iron, norfloxacin, penicillamine and tetracyclines.

See also:
What are the possible side effects of Calcium ascorbate (Q-TOX)?

Stomach upset, diarrhea, and frequent urination may occur. If any of these effects persist or worsen, notify your doctor promptly. Tell your doctor immediately if this serious side effect occurs: kidney stones. If you notice other effects not listed above, contact your doctor or pharmacist.

GI disturbances (especially at high doses) e.g. nausea, eructation, vomiting, abdominal distension, diarrhoea and constipation.

Nausea, Gastrointestinal discomfort, Belching, Vomiting, Constipation, Diarrhoea

There are no verified data on the frequency of the undesirable effects observed during treatment with Ginkgo biloba (Q-TOX)-containing preparations, since these adverse effects have become known through single reports from patients, physicians or pharmacists. According to these reports, the following side effects may occur during treatment with Ginkgo biloba (Q-TOX): Nervous System Disorders: Headache.

Vascular Disorders: Bleeding from single organs has been reported.

Gastrointestinal Disorders: Mild gastrointestinal disturbances.

Skin and Subcutaneous Tissue Disorders: Allergic skin reactions (reddening, swelling, itching).

Rare:

Abdominal Pain with Cramps, Back Pain, Blurred Vision, Constipation, Diarrhea, Dizziness, Dysuria, Erectile Dysfunction, Fatigue, Headache Disorder, Hypertension, Libido Changes, Nausea, Urinary Retention

See also:
What are the possible side effects of Methylcobalamin (Q-TOX)?

Tablet: Gastrointestinal: Symptoms eg, anorexia, nausea or diarrhea may occur infrequently.

Dermatological: Skin rash may occur rarely.

Others: Prolonged use of larger doses of Methylcobalamin (Q-TOX) is not recommended for patients whose occupation requires handling of mercury or its compounds.

Injection: Hypersensitivity: Use of Methylcobalamin (Q-TOX) should be discontinued if symptoms of hypersensitivity eg, eruptions, occur.

Others: Pain and induration may infrequently occur at the site of IM injection and headache, sweating or hot sensation may rarely occur.

See also:
What are the possible side effects of Selenium (Q-TOX)?

Applies to Selenium (Q-TOX) sulfide topical: topical cream, topical foam, topical lotion, topical shampoo, topical suspension

As well as its needed effects, Selenium (Q-TOX) sulfide topical may cause unwanted side effects that require medical attention.

Severity: Moderate

If any of the following side effects occur while taking Selenium (Q-TOX) sulfide topical, check with your doctor or nurse as soon as possible:

Less common or rare:

• Skin irritation

Minor Side Effects

Some Selenium (Q-TOX) sulfide topical side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common:

• Unusual dryness or oiliness of hair or scalp

• Increase in normal hair loss

See also:
What are the possible side effects of Ubidecarenone (Q-TOX)?

This product usually has very few side effects. Nausea, loss of appetite, upset stomach, or diarrhea may rarely occur. If any of these effects persist or worsen, contact your doctor promptly.

A very serious allergic reaction to this product is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

See also:
What are the possible side effects of Vitamin B12 (Q-TOX)?

Applies to cyanocobalamin: intramuscular solution

Other dosage forms:

• nasal gel/jelly, nasal spray

As well as its needed effects, cyanocobalamin (the active ingredient contained in Vitamin B12 (Q-TOX)) may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking cyanocobalamin, check with your doctor or nurse immediately:

Incidence not known:

• Abdominal or stomach pain
• bleeding from the gums or nose
• blue lips and fingernails
• chest pain
• cough
• coughing that sometimes produces a pink frothy sputum
• decreased urine output
• difficult, fast, noisy breathing, sometimes with wheezing
• difficulty with swallowing
• dilated neck veins
• dizziness
• extreme fatigue
• eye pain
• fast heartbeat
• headache
• hives, itching, or skin rash
• increased sweating
• irregular breathing
• irregular heartbeat
• pale skin
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• ringing in the ears
• swelling of the face, fingers, feet, or lower legs
• tightness in the chest
• unusual tiredness or weakness
• weight gain

Minor Side Effects

Some cyanocobalamin side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Incidence not known:

• Diarrhea
• skin rash with a general disease

See also:
What are the possible side effects of Vitamin E (Q-TOX)?

Applies to Vitamin E (Q-TOX): oral capsule, oral capsule liquid filled, oral liquid, oral powder for solution, oral solution, oral tablet, oral tablet chewable

In addition to its needed effects, some unwanted effects may be caused by Vitamin E (Q-TOX) (the active ingredient contained in Centrum Singles-Vitamin E (Q-TOX)). In the event that any of these side effects do occur, they may require medical attention.

Severity: Moderate

If any of the following side effects occur while taking Vitamin E (Q-TOX), check with your doctor or nurse as soon as possible:

With doses greater than 400 Units a day and long-term use

• Blurred vision
• diarrhea
• dizziness
• headache
• nausea or stomach cramps
• unusual tiredness or weakness

See also:
What are the possible side effects of Zinc (Q-TOX)?

Applies to Zinc (Q-TOX) sulfate: capsules, tablets

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur while taking Zinc (Q-TOX) sulfate (the active ingredient contained in Zinc (Q-TOX))

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe vomiting; unusual restlessness; very dry mouth, eyes, or skin.