Components:
Medically reviewed by Kovalenko Svetlana Olegovna, PharmD. Last updated on 29.05.2022
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Norgesic Forte 50 mg/770mg/60 mg Tablets are indicated in:
- Symptomatic relief of mild to moderate pain of acute musculoskeletal disorders.
- The orphenadrine component is indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute painful musculoskeletal conditions.
The mode of action of orphenadrine has not been clearly identified, but may be related to its analgesic properties. Norgesic Forte Tablets do not directly relax tense skeletal muscles in man.
Aspirin (Norgesic Forte) is in a class of drugs called salicylates. Aspirin (Norgesic Forte) works reducing substances in the body that cause pain and inflammation. It is used to reduce pain, inflammation, and fever.
Caffeine (Norgesic Forte) is used in this combination to increase the pain relieving effects of Aspirin (Norgesic Forte) and orphenadrine.
Orphenadrine is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) that are sent to the brain.
Aspirin (Norgesic Forte)/Caffeine (Norgesic Forte)/orphenadrine is used, along with rest and physical therapy, to treat injuries and other painful muscular conditions.
Aspirin (Norgesic Forte)/Caffeine (Norgesic Forte)/orphenadrine may also be used for purposes other than those listed in this medication guide.
Norgesic Forte Tablets: Adults 1/2 to 1 tablet 3 to 4 times daily.
Further information
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Medical Disclaimer
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What is the most important information I should know about Norgesic Forte?
Because of the mild anti-cholinergic effect of orphenadrine, Norgesic Forte Tablets should not be used in patients with glaucoma, pyloric or duodenal obstruction, achalasia, prostatic hypertrophy, or obstructions at the bladder neck. Norgesic Forte Tablets are also contraindicated in patients with myasthenia gravis and in patients known to be sensitive to Aspirin (Norgesic Forte) or Caffeine (Norgesic Forte).
The drug is contraindicated in patients who have demonstrated a previous hypersensitivity to the drug.
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What are the possible side effects of Norgesic Forte?
Side effects of Norgesic Forte Tablets are those seen with Aspirin (Norgesic Forte) and Caffeine (Norgesic Forte) or those usually associated with mild anticholinergic agents. These may include tachycardia, palpitation, urinary hesitancy or retention, dry mouth, blurred vision, dilation of the pupil, increased intraocular tension, weakness, nausea, vomiting, headache, dizziness, constipation, drowsiness, and rarely, urticaria and other dermatoses. Infrequently, an elderly patient may experience some degree of confusion. Mild central excitation and occasional hallucinations may be observed. These mild side effects can usually be eliminated by reduction in dosage. One case of aplastic anemia associated with the use of Orphenadrine citrate (Norgesic Forte), Aspirin (Norgesic Forte), and Caffeine (Norgesic Forte) Tablets has been reported. No causal relationship has been established. Rare G.I. hemorrhage due to Aspirin (Norgesic Forte) content may be associated with the administration of Norgesic Forte Tablets. Some patients may experience transient episodes of lightheadedness, dizziness or syncope.