Mylom

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Medically reviewed

Marina Burgos

Last updated on 10/01/2026

This page provides general, reference-level information compiled from official medical sources. It is not a substitute for professional medical advice, diagnosis, or treatment. For decisions about your health, please consult a qualified healthcare professional.

Overview of Mylom

Property Description
Active ingredient Simethicone
Form Oral suspension, emulsion (drops), chewable tablets, capsules
Pharmacological class Antiflatulent Agent
Common use Relief of gas, bloating, and abdominal pressure
Origin Synthetic silicone polymer

Defining Mylom: Identity and Pharmacological Class

Mylom is a pharmaceutical preparation whose single active component is Simethicone, placing it in the therapeutic class of antiflatulent agents or gastrointestinal agents. Simethicone is a synthetic, activated silicone polymer that is chemically a mixture of polydimethylsiloxane and silica gel, a composition clinically recognized for its defoaming properties in the gastrointestinal tract. This classification means the drug is designed to physically intervene against the symptoms associated with excessive gas accumulation and meteorism (bloating and fullness). Simethicone is used to relieve the pressure caused by excess gas in the stomach and intestines.

Composition and Available Forms of Simethicone

The drug’s formulation centers on the Simethicone compound, which acts entirely locally within the gastrointestinal tract and is not systemically absorbed into the bloodstream. Mylom is intended for oral administration and is manufactured in several standard dosage forms, including liquid preparations such as an oral suspension and emulsion (drops), alongside solid forms like chewable tablets and capsules. These various forms ensure the active substance can be delivered effectively to the site of gas accumulation to address symptoms such as post-meal abdominal pressure, supporting its function as an over-the-counter option.

General Purpose: Relieving Gas and Bloating Discomfort

The overall purpose of Mylom is to mitigate the physical symptoms—specifically bloating, fullness, and abdominal pressure—caused by trapped gas. Simethicone achieves this by acting as a surface-active substance that reduces the surface tension of small, foamy gas bubbles, causing them to collapse and coalesce. This anti-foaming action transforms the difficult-to-pass, trapped gas into larger, free gas pockets that the body can easily expel through natural processes like eructation or flatus. This immediate, physical mechanism of action provides a focused, direct benefit for gastrointestinal discomfort.

Regulatory References

  1. MedlinePlus: Simethicone
  2. NIH/StatPearls

What side effects are possible with Mylom?

Possible Side Effects and Safety Information

The safety profile of Mylom, which contains B vitamins (Thiamine/B1, Pyridoxine/B6, and Cyanocobalamin/B12), is documented in regulatory sources based on official classifications of adverse reactions and population-specific restrictions. Adverse effects are generally grouped by the body systems affected (System-Organ Classes).

Commonly Documented Adverse Reactions

The official labeling notes the possibility of non-serious effects primarily affecting the Gastrointestinal System, such as mild transient diarrhea, nausea, and vomiting. Skin and Subcutaneous Tissue Disorders may also occur, including itching (pruritus), rash, and urticaria.


Serious Adverse Reactions and Duration-Related Risks

While considered rare, the regulatory data documents potentially serious events. These include Anaphylactic Shock (a severe allergic reaction) and Peripheral Vascular Thrombosis. The Nervous System Disorders class includes the risk of developing severe peripheral neuropathies (nerve damage). This specific risk is explicitly linked to long-term intake of high doses of the Vitamin B6 component over periods of six months or longer, a pattern detailed in official prescribing information.


Safety Restrictions and Special Populations

Use of Mylom requires consideration of certain pre-existing conditions as stated in regulatory documents. It is contraindicated in individuals with a known hypersensitivity to any of the active components. Cyanocobalamin (B12) should not be used in patients with Leber's disease (hereditary optic nerve atrophy) as it may exacerbate the condition. Furthermore, the administration of B12 can potentially mask the symptoms of subacute degeneration of the spinal cord or certain types of anemia (such as folate deficiency), necessitating established diagnosis prior to treatment.

Overdose and Emergency Response

Mylom Overdose and when to seek help

This information is based exclusively on official regulatory labeling regarding documented overdose conditions for the B-vitamin complex, with a focus on Pyridoxine (Vitamin B6) toxicity.

Overdose Scope

Domain Regulatory Statements / Documented Entities
Documented Overdose Presentations Sensory neuropathy; paresthesia (tingling/numbness); gait disturbances; loss of deep tendon reflexes.
Physiological Systems Affected Peripheral nervous system (neurotoxicity).
Dose-related or Exposure-related Factors The primary risk is associated with prolonged, excessive intake over time.
Emergency-response statements Immediate discontinuation of the product is required; symptomatic and supportive treatment is necessary.
When immediate medical help is required Seek immediate medical attention upon the onset of sensory neuropathy or persistent neurological symptoms.

Overdose Classifications (High-level)

Classification Regulatory Statements / Documented Entities
Severity classification Potential for severe outcomes, specifically chronic or irreversible nerve damage associated with continued high exposure.
Overdose-context constraints Overdose management must proceed under the constraint that no specific antidote is known.

Resulting Overdose Structure

Official overdose statements:

  • Overdose may manifest as sensory neuropathy, presenting with signs such as paresthesia and difficulty with coordination or gait.
  • The primary serious outcome documented is the potential for irreversible nerve damage following chronic, excessive intake.
  • Immediate medical attention must be sought if symptoms of sensory neuropathy or other persistent neurological impairments occur.
  • The management intervention is limited to symptomatic and supportive treatment, as no specific antidote is known.

Connection to the Overall Overdose Profile

Regulatory documents define the Mylom overdose profile by the specific neurotoxicity linked to excessive B6 exposure, which dictates the required emergency actions. The profile mandates that patients seek immediate medical attention if documented neurological manifestations are observed, establishing a clear link between the onset of symptoms and the requirement for urgent, non-antidotal, supportive clinical management.

Therapeutic Uses of Mylom

Quick Facts

  • Support for nerve health: Used to provide nutritional support for the nervous system.
  • Metabolic support: Utilized to support key metabolic processes.
  • Nutritional supplementation: Indicated for managing or preventing specific vitamin deficiencies.

Mylom is a pharmaceutical preparation utilized in patient care to address deficiencies of certain B vitamins. Its primary therapeutic domains involve supporting the health and function of the nervous system and contributing to essential metabolic processes.

It is applied when a medical professional determines there is a requirement for supplementation with thiamine (B1), pyridoxine (B6), and cyanocobalamin (B12). This combination is specifically intended to support the body's natural processes that depend on these micronutrients. The therapy is used to help address symptoms associated with confirmed B vitamin deficits, assisting in the maintenance of proper nervous system function and the restoration of nutritional balance.

Eligibility and Restrictions for Use

Who Can and Cannot Use Mylom?

Mylom, which contains the active ingredient Simethicone, is an antiflatulent agent with a broad eligibility profile due to its lack of systemic absorption. Eligibility is primarily determined by allergy status and age.

Absolute Contraindication

Classification Population Status
Hypersensitivity Patients with a known allergy to Simethicone or any other component in the Mylom formulation. Must not use

Established Eligibility

Use is established across a wide range of age groups for the relief of gas and bloating. This includes adults, teenagers, children, and infants, though specific formulations (such as drops or suspension) are typically labeled for younger ages. Simethicone's regulatory status is consistent with its non-systemic action. Consequently, official prescribing information documents no specific restrictions for patients with impaired hepatic (liver) or renal (kidney) function.

Conditional Use

Classification Population Condition
Physiological State Pregnant individuals Use requires caution and should be assessed by a healthcare provider.
Physiological State Breastfeeding mothers Use is generally acceptable as the drug is not absorbed into the bloodstream.

What should I know about interactions with other medicines?

Mylom Interactions with Other Medicines and Products: Official Regulatory Information

This section outlines the officially documented interaction profile for the active ingredient, Simethicone (Mylom), based strictly on government regulatory documentation.

Simethicone is a locally acting agent that is not absorbed systemically, resulting in an interaction profile limited to physical effects within the gastrointestinal tract. No formal contraindications are listed regarding co-administration with other medicines, and no metabolic or transporter-based interactions are documented in regulatory sources.


Documented Pharmacokinetic Interaction

Property Description
Medicinal Product Category Thyroid replacement hormones (e.g., Levothyroxine).
Interaction Mechanism Decreased oral bioavailability/absorption of the co-administered thyroid medication.
Interaction Restriction Required time separation to prevent reduced exposure of the thyroid medication.

Timing-Based Administration Rules

The regulatory requirement for managing this absorption interaction specifies that medications containing thyroid replacement hormones must be administered at least 4 hours before or after the dose of Mylom. This rule is in place to ensure that the absorption of the thyroid medication is not compromised.

This limited structure confirms that the primary interaction concern defined by regulatory bodies is the physical interference with the absorption of only certain co-administered oral medications.

Mechanism of Action

How Mylom Works at a Biological Level

Mylom functions as a targeted proteasome inhibitor, a mechanism that profoundly disrupts the cell's main recycling and regulatory system, the Ubiquitin-Proteasome System (UPS). It selectively binds to and inhibits the 20S proteasome core, blocking the breakdown of essential regulatory proteins.

This primary interaction leads to the rapid accumulation of misfolded and ubiquitinated proteins within the cell. The buildup of proteins initiates severe Endoplasmic Reticulum (ER) stress and simultaneously blocks pro-survival signaling by preventing the degradation of IkappaB, thereby trapping the transcription factor NF-kappaB in the cytoplasm.

This mechanistic cascade culminates in two critical physiological consequences: cell cycle arrest (halting cell division) through the stabilization of inhibitors like p21, and the induction of programmed cell death (apoptosis) in susceptible cells.

Dosage and Administration Information

How to Use Mylom

Mylom (Simethicone) administration is governed by high-level, label-based instructions defining its use as an oral, non-systemic agent for managing gas and bloating discomfort. The medication is used intermittently, or on an as-needed basis (PRN), rather than as a continuous therapy.


Administration and Dosage Regimens

Mylom is intended exclusively for the oral route of administration. Dosing is typically scheduled after meals and at bedtime to coincide with the periods when gas discomfort is most prevalent. Official product labeling specifies dosage according to age group and product form:

  • Adults and Children 12 Years and Older: The usual dose ranges from 40 mg to 250 mg per intake. The total intake is constrained by a maximum daily dose of up to 500 mg to 640 mg in a 24-hour period, depending on the specific formulation strength. Doses can be taken up to four times daily (QID).

  • Children 2 to 12 Years: The label-specified dose is typically 40 mg per intake, with a maximum limit of 480 mg per day.

  • Infants Under 2 Years: The standard dose for the oral suspension/drops is 20 mg per intake, with a maximum daily limit of 240 mg.


Procedural and Duration Constraints

Specific instructions must be followed based on the dosage form. Chewable tablets must be thoroughly chewed before swallowing, while liquid oral suspensions must be shaken well and accurately measured using the provided dosing device. For self-medication, Mylom should generally not be taken for more than 14 consecutive days.

Recent Clinical Evidence

Research Evidence / Overview of Studies for Mylom


Research Evidence for Simethicone (Antiflatulent Agent)

Research on Relief of Gas and Bloating

Research examined short-term study patterns focusing on patient-reported outcomes describing perceived discomfort associated with gas, bloating, fullness, and abdominal pressure. These investigations was observed in as short-term Randomized Controlled Trials (RCTs) over defined time intervals, typically lasting a few weeks. Studies reported measurements of symptom changes and how symptoms evolved in the observed populations during the study period.

However, research exploring short-term symptom changes provides limited information for long-term outcomes or sustained management. Evidence remains limited and heterogeneous regarding its use for more complex, chronic conditions characterized by fluctuating or episodic manifestations.

Research on Use in Medical Procedures

Simethicone was studied for use as an additive to the bowel preparation process ahead of procedures like colonoscopy. These studies monitored the measurements of mucosal visualization within the intestinal tract. Studies exploring short-term symptom changes reported measurements of mucosal visualization when Simethicone was co-administered with the standard preparation regimen. These studies primarily serve the purpose of research into procedural outcomes and do not address the drug's use for general, daily gas discomfort.


Research Evidence for the B Vitamin Combination (B1, B6, B12)

Research on Correcting Nutritional Deficiencies

The B vitamin combination was evaluated in studies examining patient-reported experiences and monitoring outcomes related to systemic or functional imbalance caused by confirmed deficits of Thiamine (B1), Pyridoxine (B6), or Cyanocobalamin (B12). Findings help contextualize how patients reported their experience and consistently indicate changes measured during the study period related to correcting these imbalances in deficient populations.

Research so far suggests that results apply primarily to populations with confirmed, measurable deficiencies. Research highlights what is known—and what is still uncertain—about the optimal duration and regimen needed to maintain the corrected levels over extended periods.

Research on Nervous System and Pain Support

The B vitamin combination was observed in research contexts involving fluctuating or unstable symptoms, applied in studies examining outcomes linked to inflammatory or irritative states such as peripheral neuropathy. In the context of pain, the combination was studied for an adjuvant (add-on) role, often alongside standard pain relievers in short-term RCTs. Studies reported measurements related to symptom severity when the B vitamins were co-administered. However, comparative evidence is lacking when the B vitamin combination is used alone for pain relief. For nerve health, research provides insight into short-term changes, but long-term effects are not fully established.

Key Studies & References

  1. Simethicone - StatPearls - NCBI Bookshelf
  2. Efficacy and Safety of Combining NSAIDs with Vitamin B for Musculoskeletal Pain: A Systematic Review and Meta-Analysis
  3. Vitamin B12 in low back pain: a randomised, double-blind, placebo-controlled study
  4. Simethicone: MedlinePlus Drug Information

Frequently Asked Questions (FAQ)

Common questions about Mylom (FAQ)

Q: Are there any long-term health effects associated with taking Mylom for many years?

The active ingredient in Mylom, Simethicone, is not systemically absorbed into the bloodstream. Information regarding long-term systemic side effects is limited in the regulatory literature, given the non-systemic nature of the drug. Official guidance defines the intended duration of use as typically not exceeding 14 consecutive days.

Q: What should a patient know about the risks versus the benefits of Mylom?

The primary benefit of Mylom is providing relief from the physical symptoms of gas, such as pressure and bloating. Due to the lack of systemic absorption of the active ingredient, the risk profile is considered low compared to absorbed drugs. The main potential risk noted in official regulatory information is the possibility of reduced absorption of co-administered thyroid replacement hormones.

Q: What is the typical long-term outcome described for people using Mylom?

Mylom is intended for use on an as-needed or short-term basis to address acute gastrointestinal discomfort. Because the medication is non-systemic and acts only physically in the digestive tract, its official regulatory profile does not focus on long-term systemic health outcomes.

Q: Does Mylom have specific warnings for older adults (geriatric population)?

Official product information does not contain specific data comparing the use of Mylom's active ingredient in older adults to its use in younger age groups. However, the ingredient is generally available for use in the overall adult population.

Q: What is the expected timeline before a person might notice effects from Mylom?

Mylom works by a physical anti-foaming mechanism directly within the digestive tract. This local action, combined with its short duration of action, generally suggests the potential for prompt local relief from symptoms like bloating and pressure.

Q: What happens if a dose of Mylom is missed?

General regulatory guidance often notes that if a dose is missed, it may be taken when remembered. However, if the time for the next scheduled dose is near, the missed dose is typically skipped to prevent accidentally exceeding the recommended intake. The individual’s established dosing routine is then maintained.

Q: Can Mylom interact with common over-the-counter (OTC) medicines?

Official regulatory information indicates that Mylom is generally noted to have a limited interaction profile with other medicines. The only widely documented pharmaceutical interaction involves the potential for Mylom to reduce the absorption of certain prescription thyroid replacement hormones. It remains important to check the product formulation for other active ingredients that may carry broader interaction profiles.

Q: Is the consumption of alcohol generally advised against while taking Mylom?

Due to the active ingredient not being systemically absorbed into the bloodstream and lacking effects on the central nervous system (CNS), official regulatory information for the single-ingredient product does not typically include standard warnings about alcohol consumption.

Q: Does Mylom carry any warnings about operating machinery or driving?

Warnings regarding activities like driving or operating heavy machinery are usually reserved for medications that are absorbed systemically and affect the central nervous system. Because Mylom's active ingredient is non-systemic and does not typically cause CNS side effects, such warnings are not commonly listed in the official labeling.

Q: What kind of monitoring (e.g., blood tests) is typically required when taking Mylom?

Since the active ingredient in Mylom is not systemically absorbed into the bloodstream, no blood tests or specific systemic monitoring requirements are described in the regulatory literature for the single-ingredient product.

Q: Is Mylom an FDA-approved drug?

Yes, the active component of Mylom, Simethicone, is a substance that has been in use for many decades. Official records indicate that the ingredient was granted FDA approval in 1952.

Q: Does the official information for Mylom describe a risk of dependence or withdrawal?

Official regulatory labeling does not list any risks related to dependence, tolerance, or withdrawal for the active ingredient. This is consistent with its pharmacological class, as the medication is non-systemic and acts only physically in the digestive tract.

Q: Does Mylom interact with any herbal remedies like St. John’s Wort?

Regulatory sources typically state that due to a lack of specific testing, sufficient information is not available to confirm the co-administration of herbal remedies or supplements alongside Mylom. This is because such products are often not tested under the same strict regulatory standards as standardized medications.

How should Mylom be stored and disposed of?

How to Store and Dispose of Mylom (Simethicone)

The official labeling defines specific storage and disposal requirements for Mylom to ensure its stability and safe handling.

Storage Conditions

Detail Regulatory Requirement
Temperature Store at controlled room temperature, between 68°F and 77°F (20°C and 25°C).
Protection Do not freeze and avoid excessive heat. Keep the container tightly closed and away from high humidity.
Safety Store the medication out of the sight and reach of children.

Disposal Instructions

Unused or expired Mylom should be disposed of via a drug take-back program. If a program is unavailable, mix the product with an undesirable substance (e.g., dirt) in a sealed bag before placing it in the household trash. Do not flush the medication down a toilet or pour it into any drain.

Attention! Always consult to a doctor or pharmacist before using pills or medicines.

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